4.4 Article

Two new flavan-4-ol glycosides from Abacopteris penangiana

Journal

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 12, Issue 5, Pages 355-359

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/10286021003764453

Keywords

Amaranthaceae; Abacopteris penangiana; flavan-4-ol glycoside; antitumor activity

Funding

  1. Scientific Research Foundation of Tianjin Medical University

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Two new flavan-4-ol glycosides, (2R,4S)-6,8-dimethyl-7-hydroxy-4'-methoxy-4,2''-oxidoflavan-5-O--d-6''-O-acetyl-glucopyranoside (1) and (2R,4S)-5,7-O--d-di-glucopyranosyloxy-4'-methoxy-6,8-dimethyl-4,2''-oxidoflavane (2), were isolated from the rhizomes of Abacopteris penangiana. Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 showed significant anticancer activities against HeLa and L929 cell lines in vitro.

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