Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 10, Issue 11, Pages 1003-1008Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020802242364
Keywords
Paulownia tomentosa var; tomentosa; epimeric phenylethanoid glycoside; isoilicifolioside A; anti-complementary activity
Funding
- China Postdoctoral Science Foundation [20070410198]
- Natural Science Foundation of Tianjin City and Scientific Research Foundation
- State Education Ministry, China [2008-101]
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Four epimeric phenylethanoid glycosides, including a new one, R,S--ethoxy--(3,4-dihydroxyphenyl)-ethyl-O--l-rhamnopyranosyl(13)--d-(6-O-E-caffeoyl)-glucopyranoside named isoilicifolioside A (1), and three known compounds, ilicifolioside A (2), campneoside II (3), and isocampneoside II (4), were isolated from Paulownia tomentosa var. tomentosa wood. The structures of the four compounds were elucidated by the interpretation of 1D and 2D NMR and MS spectra. This is the first report of the chemical profile of this tree. Compounds 1-4 exhibited excellent anti-complement activity with IC50 values less than 74M, compared with tiliroside (IC50=104M) and rosmarinic acid (IC50=182M) that were used as positive controls.
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