Article
Plant Sciences
Ying Qi, Lingling Ma, Muhammad Imran Ghani, Qiang Peng, Ruidong Fan, Xiaojing Hu, Xiaoyulong Chen
Summary: The study found that drought stress has a significant impact on the growth and physiological indices of passion fruit. Drought stress induced by PEG can significantly decrease fresh weight, chlorophyll content, and root vitality, while increasing the contents of soluble protein, proline, and malondialdehyde. The activities of antioxidant enzymes showed an increasing trend and then a decreasing trend, with the highest value at the sixth day of drought stress. Among all the stress treatments, 20% PEG had the most significant effect on passion fruit seedlings.
Article
Biochemistry & Molecular Biology
Ahlem Meziadi, Navid Zuberi, Hendrick W. de Haan, Marc A. Gauthier
Summary: This study reveals that the inefficiency of bioconjugation reactions, such as protein PEGylation, is caused by the excluded volume effect (EVE) between methoxy poly(ethylene glycol) (mPEG) and proteins. The researchers found that this EVE leads to the self-assembly of proteins and reactive mPEG into separate protein-rich and mPEG-rich domains. By adding unreactive low-molecular weight mPEG as a co-solvent, the association between the larger protein and reactive mPEG can be promoted, resulting in improved reaction efficiency.
Article
Forestry
Ladislav Reinprecht, Miroslav Repak, Jan Izdinsky, Zuzana Vidholdova
Summary: European beech wood has potential for construction and decorative materials, but its resistance to decaying fungi and insects is low. The study shows that treating beech wood with nano-zinc oxide can significantly improve its resistance to brown-rot and white-rot fungi, especially when combined with thermal modification.
Article
Multidisciplinary Sciences
Novilda Elizabeth Mustamu, Koko Tampubolon, Alridiwirsah, Mohammad Basyuni, Duraid K. A. AL-Taey, Haider Jawad Kadhim A. L. Janabi, Mohammad Mehdizadeh
Summary: Drought stress has a negative impact on maize growth and yield. This study aimed to identify drought-tolerant maize varieties and found that local accessions BI3, SB5, DS2, and MN3, as well as the hybrid variety H, showed tolerance to drought stress. Increasing levels of Polyethylene glycol 6000 caused a decrease in germination characteristics and growth parameters. The drought tolerance indexes indicated that H, SB5, DS2, MN3, and BI3 are drought-tolerant maize varieties.
Article
Chemistry, Multidisciplinary
Morgan D. McSweeney, Limei Shen, Alexander C. DeWalle, Jordan B. Joiner, Elizabeth C. Ciociola, Dharmendra Raghuwanshi, Matthew S. Macauley, Samuel K. Lai
Summary: This study explored the effectiveness of prophylaxis with free PEG or tolerogenic PEGylated liposomes as a strategy to reduce the amount of APA induced by subsequently administered PEGylated liposomes. The results showed that a single administration of free PEG alone was capable of markedly reducing the APA response to PEG-liposomes for up to 2 months, which was comparable to, and often exceeded, interventions with different tolerogenic PEG-liposomes. These findings support further research on free PEG prophylaxis as a potential strategy to mitigate the APA response to sensitizing PEGylated therapeutics.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Biochemistry & Molecular Biology
Asim Mushtaq, Li Li, A. Anitha, Lisbeth Grondahl
Summary: This study synthesized methoxy polyethyleneglycol grafted chitosan (mPEG-CHI) using carbodiimide-mediated coupling and evaluated the effect of reaction conditions on the degree of substitution and PEGylation yield. The optimized conditions resulted in a high DS and PEGylation yield, making the product suitable for medical applications. The cytotoxicity of mPEG-CHI was also assessed and found to be non-toxic against breast cancer cell lines.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Taro Shimizu, Mizuki Awata, Amr S. Abu Lila, Chihiro Yoshioka, Yoshino Kawaguchi, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida
Summary: In this study, we developed a delivery system using hydroxy PEG-modified liposomes (HO-PEG-Lip) that efficiently activated the complement system, facilitated the association with MZ-B cells, and significantly enhanced antigen delivery in vivo. The manipulation of HO-PEG density at 2 mol% in total lipids led to a successful induction of OVA-specific IgG response after a single intravenous injection. This new delivery technique may provide a simple and effective way to deliver antigens to MZ-B cells, inducing a significant humoral immune response.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Materials Science, Biomaterials
Kai Sugiura, Toshiki Sawada, Yuuki Hata, Hiroshi Tanaka, Takeshi Serizawa
Summary: This study demonstrates a simple method for distinguishing anti-PEG antibodies using antibiofouling cello-oligosaccharide assemblies tethering specific one-terminal methoxy oligo(ethylene glycol) ligands. The method allows for quantitative detection of the antibodies, even in the presence of serum.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Environmental Sciences
S. P. Keerthana, R. Yuvakkumar, P. Senthil Kumar, G. Ravi, S. Hong, Dhayalan Velauthapillai
Summary: In this study, polyethylene glycol-assisted antimony tungstate nanorod photocatalysts were prepared via a hydrothermal route. The properties of the catalysts were investigated, and it was found that the 10 ml PEG-assisted sample exhibited a narrow bandgap and nanorod growth without agglomeration. Fourier transform infrared spectroscopy and Raman spectroscopy confirmed the composition and vibrational modes of the samples. Furthermore, the prepared 10 ml PEG-Sb2WO6 photocatalyst showed high efficiency and stability in degrading toxic pollutants in wastewater, making it a promising candidate for water treatment applications.
Article
Medicine, Research & Experimental
Tien-Ching Chang, Bing-Mae Chen, Jer-Yuan Wu, Tian-Lu Cheng, Steve Roffler
Summary: Antibodies that bind polyethylene glycol (PEG) can accelerate the clearance of pegylated medicines, with higher affinity antibodies leading to greater clearance and reduced drug efficacy. The molar ratio of high affinity anti-PEG antibodies to PEG-EPO correlates with accelerated blood clearance in mice.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Chemistry, Multidisciplinary
Anne M. Talkington, Morgan D. McSweeney, Timothy Wessler, Marielle K. Rath, Zibo Li, Tao Zhang, Hong Yuan, Jonathan E. Frank, M. Gregory Forest, Yanguang Cao, Samuel K. Lai
Summary: PEGylation is commonly used to prolong the circulation time of protein therapeutics and nanomedicines. However, individuals exposed to PEGylated therapeutics may develop antibodies specific to PEG, increasing the risk of hypersensitivity and accelerated drug clearance. In this study, a PBPK model was developed to investigate the impact of anti-PEG antibodies on the pharmacokinetics and biodistribution of PEGylated drugs.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Plant Sciences
Yuhui Guo, Dongxiao Li, Liantao Liu, Hongchun Sun, Lingxiao Zhu, Ke Zhang, Haiming Zhao, Yongjiang Zhang, Anchang Li, Zhiying Bai, Liwen Tian, Hezhong Dong, Cundong Li
Summary: The study shows that seed priming with melatonin can alleviate the adverse effects of drought stress on seed germination and seedling growth in triticale. Melatonin treatment improves germination rate and growth indicators, and enhances photosynthesis and antioxidant enzyme activities in seedlings.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Electrochemistry
Muhammad Ibadurrohman, Klaus Hellgardt
Summary: This paper investigates the effects of polyethylene glycol (PEG) as a template on the morphology and photoelectrochemical properties of spray-pyrolyzed TiO2 films. The results show that the concentration of PEG plays a more important role than its molecular weight in enhancing the morphology and PEC properties of the films. PEG-modified TiO2 films exhibit higher PEC efficiency and lower charge-transfer resistance.
JOURNAL OF APPLIED ELECTROCHEMISTRY
(2022)
Article
Polymer Science
Chen Zhang, Zhanping Zhang, Yuhong Qi
Summary: Introducing polystyrene microspheres into hydrogels can significantly improve the compressive strength and swelling degree, while gradually reducing the surface energy of the hydrogels.
Article
Construction & Building Technology
Zhaohui Min, Qichang Wang, Yuxiang Xie, Jiaqin Xie, Bo Zhang
Summary: In this study, the toughness and low-temperature resistance of epoxy asphalt have been successfully improved by introducing PEG with different molecular weights, showing great potential for practical applications.
CONSTRUCTION AND BUILDING MATERIALS
(2021)
Article
Ecology
Narendra Nelli, Diana Francis, Ricardo Fonseca, Olivier Masson, Mamadou Sow, Emmanuel Bosc
Summary: This study investigates the changes in the atmospheric electric field (Ez) during foggy conditions in the hyperarid region of the United Arab Emirates. The results show that as fog persists, Ez becomes more variable due to the absorption and redistribution of charges by the fog, which alters the ion balance and affects electrical conductivity in the atmosphere.
JOURNAL OF ARID ENVIRONMENTS
(2024)
Article
Ecology
Ezra Hadad, Amir Balaban, Jakub Z. Kosicki, Reuven Yosef
Summary: This study investigated whether the prey of striped hyenas has adapted to the change in the natural environment caused by human activities, particularly artificial light at night (ALAN). The results showed that ALAN had no impact on the diet or den distribution of the hyenas in central Israel. The study also found that domestic animals were the most common prey, and there were also some vegetative species in their diet. Overall, the feeding behavior of striped hyenas is influenced by geographical region, habitat, and human activities.
JOURNAL OF ARID ENVIRONMENTS
(2024)
Article
Ecology
Rahim Najafi Tireh Shabankareh, Pardis Ziaee, Mohammad Javad Abedini
Summary: This study evaluated the IMERG satellite-based precipitation product in the Fars province of Iran using daily rain gauges as reference data. The results showed that the product tends to overestimate light rainfall and underestimate heavy rainfall, with the best performance in the 40-80 mm/day range. The accuracy of the product varies by month and is less biased in months with milder temperatures. Additionally, there was a higher correlation in mid-elevated areas, positive bias in low-elevated areas, and negative bias in high-elevated areas. Longer time scales showed considerable improvement in the IMERG estimates.
JOURNAL OF ARID ENVIRONMENTS
(2024)
