Article
Respiratory System
Jennifer A. Bartell, Lea M. Sommer, Rasmus L. Marvig, Marianne Skov, Tacjana Pressler, Soren Molin, Helle Krogh Johansen
Summary: The study reveals that some CF patients may continue to be infected with Pseudomonas aeruginosa even after antibiotic therapy, suggesting the need for tailored antibiotic treatment. It also finds that most patients' infections are associated with surgery, and persistent infection is due to the re-emergence of the same strain rather than re-infection from the environment.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Multidisciplinary Sciences
Naoki Ashida, Yohei Maeda, Takahiro Kitamura, Masaki Hayama, Takeshi Tsuda, Ayaka Nakatani, Sho Obata, Kazuya Takeda, Hitoshi Akazawa, Fumitaka Inaba, Naohiro Hosomi, Atsuhiko Uno, Hidenori Inohara
Summary: Isolated sphenoid sinus opacifications (ISSOs) can lead to serious complications, but many patients are asymptomatic and may not receive proper treatment from otolaryngologists. This study revealed that a significant number of patients with ISSOs who should be treated by otolaryngologists were not referred to the otolaryngology department, emphasizing the importance of raising awareness among other clinicians.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Dmitry Tretiakow, Krzysztof Tesch, Karolina Markiet, Andrzej Skorek
Summary: This study analyzed the aeration of the maxillary sinuses using computational fluid dynamics (CFD) method based on individual adult patients' CT scans, and found that the lower part of nasal septal deviation (NSD) has the most significant impact on airflow change.
SCIENTIFIC REPORTS
(2022)
Article
Biology
Barak M. Spector, Dennis J. Shusterman, Andrew N. Goldberg, Edward M. Weaver, Alexander A. Farag, Bradley A. Otto, Kai Zhao
Summary: This study measured exhaled nasal NO tracings and performed computational fluid dynamics NO emission simulations to reveal that ethmoid sinuses contribute the most to total nasal NO emission and diffusion plays a greater role than convective transport. Turning off diffusion reduced the NO emission peaks by over 70%. These findings may significantly impact our understanding of nasal NO emission mechanisms and sinus physiopathology.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Medicine, General & Internal
Jin Youp Kim, Su Hwan Kim, Pilkeun Jang, Yuju Seo, Sung-Woo Cho, Jeong-Whun Kim, Doo Hee Han, Hyun Jik Kim, Dong-Young Kim, Chae-Seo Rhee, Tae-Bin Won
Summary: This study compared the recurrence rates of inverted papillomas (IPs) originating from the maxillary sinus (MS) according to different surgical approaches. The results showed that expanded endoscopic approaches (ExEAs) had significantly lower recurrence rates compared to endoscopic resection via middle or inferior meatus antrostomy (ESS) and ESS with Caldwell-Luc approach or canine fossa trephination (ESS with CL) groups. Additionally, the ExEA group had a shorter postoperative hospitalization period.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Prashant Gupta, Hardeep Singh Malhotra, Priyamvada Saxena, Riddhi Singh, Deeksha Shukla, Mohd Saqib Hasan, Veerendra Verma, Gopa Banerjee, Bipin Puri, Himanshu Dandu
Summary: An epidemic of mucormycosis occurred in Uttar Pradesh, India after the second wave of COVID-19. This study aimed to assess the trends in minimum inhibitory concentration (MIC) of antifungal agents and provide a template for personalized therapy. The results showed that identification at the species level is necessary, as fungal susceptibility varies among different species.
JOURNAL OF INVESTIGATIVE MEDICINE
(2022)
Article
Otorhinolaryngology
A. Vinciguerra, D. Mattavelli, M. Turri-Zanoni, M. Ferrari, A. Schreiber, V. Rampinelli, I. Dohin, M. Valentini, V. Pontillo, P. Gaudioso, A. Karligkiotis, S. Atallah, F. Chatelet, T. Saccardo, C. Piazza, B. Verillaud, P. Nicolai, P. Castelnuovo, P. Herman
Summary: This study aimed to describe the outcomes and major prognostic factors of patients with inverted papilloma of the maxillary sinus (IPMS) treated with trans-nasal endoscopic medial maxillectomy (EMMs). The results showed that EMMs tailored to the surgical insertion point can effectively control IPMS and reduce the risk of recurrence.
Review
Medicine, General & Internal
Vini Mehta, Gargi S. Sarode, Vishnu Teja Obulareddy, Tanvi Sharma, Shruti Kokane, Marco Cicciu, Giuseppe Minervini
Summary: This review aims to investigate the complications, survival, recurrence rate, and outcomes of sinonasal ameloblastoma (SNA). The study found that SNA has similar histological features to gnathic ameloblastoma but presents different clinical characteristics. It may cause nasal cavity and sinus obstruction and primarily affects older patients. Treatment may involve excising a significant portion of the maxilla, requiring maxillofacial prosthetic rehabilitation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Ali Hassan A. Ali, Omar O. Serhan, Mohammed H. Karrar Alsharif, Abubaker Y. Elamin, Sameer Al-Ghamdi, Khaled K. Aldossari, Naif Alrudian, Mansour Alajmi, Bader A. Alhariqi, Mohammad Mokhatrish, Velmurugan Palanivel
Summary: The paranasal sinuses are air-filled cavities surrounding the nasal cavity. Inflammatory conditions are the most common pathological processes affecting the sinuses. Our study aimed to determine the prevalence of incidental paranasal sinuses abnormalities among patients who underwent head CT scanning. The results revealed a high prevalence of sinus abnormalities in asymptomatic Saudi patients, with a higher rate in males.
Article
Veterinary Sciences
Lisa Koehler, Ellen Schulz-Kornas, Ingrid Vervuert, Claudia Gittel, Karsten Winter, Dagmar Berner, Kerstin Gerlach
Summary: The study found that the structure and shape of the paranasal sinus system in Shetland ponies is similar to large horses, with seven sinus compartments and a bilateral cranial and caudal system. There is a positive correlation between the size of the paranasal sinuses and head length, but the relationship between sinus volumes and age in adult ponies over six years old could not be proven.
BMC VETERINARY RESEARCH
(2021)
Review
Clinical Neurology
Mahmoud S. Taha, Mahmoud Haddad, Ali A. Almomen, Marwa M. Abdulkader, Rami A. Alhazmi
Summary: Invasive aspergillosis of the central nervous system is rare in immunocompetent patients and commonly originates from nasal sinus infection. Despite surgical intervention and long courses of antifungal treatment, the clinical prognosis remains unfavorable in many cases.
Article
Otorhinolaryngology
Agata Kaluzna-Mlynarczyk, Beata Pucher, Jakub Sroczynski, Michal Kotowski, Katarzyna Jonczyk-Potoczna, Jaroslaw Szydlowski
Summary: This study evaluated the development of paranasal sinuses in pediatric population with cystic fibrosis (CF) compared to healthy children through CT scans. The results showed that the volume and development of sinuses increased with age in both groups, with statistically significant differences between the CF group and the control group.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Engineering, Biomedical
Andrea L. Schilling, Erin Cannon, Stella E. Lee, Eric W. Wang, Steven R. Little
Summary: Controlled drug delivery is an important strategy for increasing local therapeutic concentrations in hard-to-reach areas. This review focuses on biomaterial-based systems for delivering anti-inflammatory, antibiotic, decongestant, and antihistamine medications to the sinonasal mucosa. Various delivery vehicles, including nasal packs, dressings, sinus stents, polymeric meshes, nanoparticles, microparticles, and in situ hydrogels, are discussed. The combination of these vehicles offers enhanced therapeutic delivery and greater control of release duration.
Review
Oncology
Florian Chatelet, Francois Simon, Vincent Bedarida, Nicolas Le Clerc, Homa Adle-Biassette, Philippe Manivet, Philippe Herman, Benjamin Verillaud
Summary: Sinonasal cancers are rare and require surgery as the first step of the therapeutic strategy, possibly accompanied by adjuvant therapies. Surgical excision can be performed through open, endoscopic, or combined approaches, with the choice based on general and specific criteria related to tumor characteristics, patient status, and surgeon preference. This review provides an overview of surgical techniques for sinonasal malignant tumors, with a focus on recent advancements in transnasal endoscopic surgery, and discusses criteria for selecting appropriate techniques based on oncological outcomes, morbidity, and histologic subtypes.
Article
Oncology
Ahmed S. Abdelmeguid, Watchareporn Teeramatwanich, Dianna B. Roberts, Moran Amit, Renata Ferraroto, Bonnie S. Glisson, Michael E. Kupferman, Shirley Y. Su, Jack Phan, Adam S. Garden, Shaan M. Raza, Franco DeMonte, Ehab Y. Hanna
Summary: Induction chemotherapy plays a significant role in locally advanced sinonasal squamous cell carcinoma, leading to improved outcomes and organ preservation.
Article
Biochemistry & Molecular Biology
Maja Krzewinska, Anna Kjellstrom, Torsten Guenther, Charlotte Hedenstierna-Jonson, Torun Zachrisson, Ayca Omrak, Reyhan Yaka, Gulsah Merve Kilinc, Mehmet Somel, Veronica Sobrado, Jane Evans, Conine Knipper, Mattias Jakobsson, Jan Stora, Anders Gotherstrom
Article
Genetics & Heredity
Magdalena M. Bus, Maria Lembring, Anna Kjellstrom, Christina Strobl, Bettina Zimmermann, Walther Parson, Marie Allen
FORENSIC SCIENCE INTERNATIONAL-GENETICS
(2019)
Article
Paleontology
Anne-Marijn Van Spelde, Hannes Schroeder, Anna Kjellstrom, Kerstin Liden
Summary: This paper reviews the evolution and application of research methods on bone loss in the past, as well as the challenges and limitations. Paleopathology studies have revealed differences in bone loss between different archaeological populations, but methodological diversity has also introduced complexity in interpreting the results.
INTERNATIONAL JOURNAL OF PALEOPATHOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Ricardo Rodriguez-Varela, Kristjan H. S. Moore, S. Sunna Ebenesersdottir, Gulsah Merve Kilinc, Anna Kjellstrom, Ludvig Papmehl-Dufay, Clara Alfsdotter, Birgitta Berglund, Loey Alrawi, Natalija Kashuba, Veronica Sobrado, Vendela Kempe Lagerholm, Edmund Gilbert, Gianpiero L. Cavalleri, Eivind Hovig, Ingrid Kockum, Tomas Olsson, Lars Alfredsson, Thomas F. Hansen, Thomas Werge, Arielle R. Munters, Carolina Bernhardsson, Birgitte Skar, Axel Christophersen, Gordon Turner-Walker, Shyam Gopalakrishnan, Eva Daskalaki, Ayca Omrak, Patxi Perez-Ramallo, Pontus Skoglund, Linus Girdland-Flink, Fredrik Gunnarsson, Charlotte Hedenstierna-Jonson, M. Thomas P. Gilbert, Kerstin Liden, Mattias Jakobsson, Lars Einarsson, Helena Victor, Maja Krzewinska, Torun Zachrisson, Jan Stora, Kari Stefansson, Agnar Helgason, Anders Gotherstrom
Summary: We analyze a 2,000-year genetic study of Scandinavia, using 48 new and 249 published ancient genomes and genotypes from 16,638 modern individuals. Our findings reveal regional variation in gene flow from the eastern Baltic, the British-Irish Isles, and southern Europe. British-Irish ancestry was common in Scandinavia during the Viking period, while eastern Baltic ancestry was more localized to Gotland and central Sweden. We also observe a decrease in current levels of external ancestry in some regions, suggesting less contribution from ancient immigrants to the modern Scandinavian gene pool compared to earlier periods.
Article
Anthropology
Rose Drew, Anna Kjellstrom
Summary: This study compares sacra and lower lumbar vertebrae from two historical shipwrecks and finds a true prevalence of complete sacralization of 16.7% in both crews, with variations of LSTV present in 38.3% of one crew and 26.7% of the other. The high rates of sacralization in both crews may be related to their similar populations.
INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY
(2021)
Article
Archaeology
Elin Ahlin Sundman, Anna Kjellstrom
EUROPEAN JOURNAL OF ARCHAEOLOGY
(2020)
Article
Archaeology
Clara Alfsdotter, Anna Kjellstrom
EUROPEAN JOURNAL OF ARCHAEOLOGY
(2019)
Article
Anthropology
Neil Price, Charlotte Hedenstierna-Jonson, Torun Zachrisson, Anna Kjellstrom, Jan Stora, Maja Krzewinska, Torsten Guenther, Veronica Sobrado, Mattias Jakobsson, Anders Gotherstrom
Meeting Abstract
Anthropology
Anna S. E. Kjellstrom
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2019)
Article
Archaeology
Maja Krzewinska, Anna Kjellstrom, Ylva Backstrom, Anne Ingvarsson, Natalija Kashuba, Ricardo Rodriguez Varela, Linus Girdland-Flink, Anders Gotherstrom
JOURNAL OF ARCHAEOLOGICAL SCIENCE-REPORTS
(2018)
Meeting Abstract
Anthropology
Fredrik Hallgren, Sara Gummesson, Anna Kjellstrom
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2018)
Article
Anthropology
Sara Gummesson, Fredrik Hallgren, Anna Kjellstrom
Meeting Abstract
Anthropology
Anna S. E. Kjellstrom, Sara Gummesson, Fredrik Hallgren
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2017)
Meeting Abstract
Anthropology
Clara Alfsdotter, Anna Kjellstrom
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2017)
Article
Anthropology
Charlotte Hedenstierna-Jonson, Anna Kjellstrom, Torun Zachrisson, Maja Krzewinska, Veronica Sobrado, Neil Price, Torsten Gunther, Mattias Jakobsson, Anders Gotherstrom, Jan Stora
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2017)
Article
Anthropology
Julia Becher, Alex Schoeman, Gavin Whitelaw, Stephen Buckley, Jean-Pierre Celliers, Sara Cafisso, Matthias Belser, Maxime Rageot, Cynthianne Spiteri
Summary: This study represents the first application of Organic Residue Analysis (ORA) to southern African early farming pottery to gain a deeper understanding of past human behavior and subsistence patterns. The study found evidence of dairy processing and multi-purpose functionality of the ceramics. It also discovered potential medicinal use and the involvement of dung in pottery sealing and mending.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2024)
Article
Anthropology
Jon Clindaniel, Matthew Magnani
Summary: Large sources of digital trace data have become important in the study of material culture. The authors introduce a computational method to observe digital formation processes and highlight the importance of accounting for these processes in studies utilizing digital trace data.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2024)
Article
Anthropology
Rebecca A. G. Reid, Miranda M. E. Jans, Lesley A. Chesson, Rebecca J. Taylor, Gregory E. Berg
Summary: Chemical treatment of skeletal remains can reduce overall DNA quality and quantity but has no significant impact on stable isotope ratio analysis. Examination of treated and untreated human remains through histological and stable isotope analysis reveals that treated remains exhibit better preservation compared to untreated remains. Stable isotope ratio analysis is viable for both treated and untreated remains, regardless of their origin.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2024)
Article
Anthropology
Laura Tome, Eneko Iriartec, Antonio Blanco-Gonzalez, Margarita Jambrina-Enriquez, Natalia Eguez, Antonio V. Herrera-Herrera, Carolina Mallola
Summary: This paper presents the outcomes of a microcontextual geoarchaeological study conducted on earthen dwellings from the Early Iron Age village of Cerro de San Vicente. The study employed soil micromorphology, lipid biomarker analysis, XRD, and XRF analyses to investigate various aspects of the dwellings, including construction materials, site formation processes, and daily life practices. The results have shed light on the construction layers, floor use, maintenance, repaving, periods of abandonment and decay, and the presence of lipid biomarkers associated with dwelling functionality. The study significantly contributes to our understanding of ancient construction practices and the utilization of domestic spaces during the Early Iron Age.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2024)
