Article
Biochemistry & Molecular Biology
Wenyu Liang, Wenjuan Yang, Sadman Sakib, Igor Zhitomirsky
Summary: This research reports the advanced pseudocapacitive properties of magnetic CuFe2O4 nanoparticles in the negative potential range, suggesting their potential as a promising MOPC and advanced electrode material for supercapacitors. The material exhibits high capacitance and nearly ideal pseudocapacitive behavior in a large potential window, and good electrochemical performance is achieved with the use of additives and co-dispersants.
Article
Chemistry, Multidisciplinary
Mohamad Zandieh, Juewen Liu
Summary: Nanozyme refers to various catalysts, including immobilized inorganic metal complexes, immobilized enzymes, and inorganic nanoparticles. This article provides a detailed history of nanozymes and categorizes them into two types. The definition of nanozymes is evolving and can cover most claimed nanozymes based on the same substrates and products as enzymes, although with different mechanisms. A broader definition can inspire application-based research using nanomaterials for analytical, environmental, and biomedical purposes. Understanding the catalytic mechanism of nanozymes is crucial for further engineering of active sites, and the future perspective of the nanozyme field is discussed.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Analytical
Yingjie Zhao, Li Tian, Shiqi Wu, Xin Zhang, Zhuo Sun, Yue Hu, Yue Wang, Ruizhan Chen, Juan Lu
Summary: A sensitive ECL sensor for permethrin detection was developed based on Fe2O3 and Au NPs, showing enhanced ECL response and efficient detection of permethrin within a certain concentration range. The proposed strategy can provide a simple and reliable approach for pesticide detection, indicating great application prospects.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Physical
Zhe Yang, Shuwang Wu, Yun Gao, Dandan Kou, Kuan Lu, Can Chen, Yi Zhou, Dandan Zhou, Lei Chen, Jianxian Ge, Cang Li, Jianfeng Zeng, Mingyuan Gao
Summary: This study investigates the degradation of iron oxide nanoparticles under biologically relevant conditions, revealing that acidic environment, presence of bovine serum albumin, glutathione, and sodium citrate all have different effects on the degradation rate. The dissolution and aggregation of nanoparticles significantly impact their relaxivity, which has implications for their use as magnetic resonance imaging contrast agents.
Review
Materials Science, Biomaterials
Ruixue Wei, Youzhi Xu, Mengzhou Xue
Summary: Hollow iron oxide nanoparticles are a promising class of nanostructures with low toxicity, good biocompatibility, and intrinsic magnetic properties, making them attractive in biomedical applications. Various strategies for synthesis, surface functionalization, and biomedical applications of hollow iron oxide nanoparticles have been reviewed, highlighting their potential in magnetic resonance imaging, drug delivery, and cancer therapy. Prospects for further development of hollow iron oxide nanoparticles have also been discussed.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Environmental Sciences
Mei Li, Yan Kang, Haoqin Ma, Jiahao Dong, Yuqi Wang, Shaoping Kuang
Summary: The treatment of heavy metal ion contamination in aquatic ecosystems has been a global concern. Iron oxide nanomaterials are effective in heavy metals removal, but face challenges due to Fe(III) precipitation and poor reusability. To improve the removal of heavy metals, iron-manganese oxide material (FMBO) was prepared. FMBO showed higher removal capacities for Cd(II), Ni(II), and Pb(II) compared to FeOOH. Mass spectrometry analysis revealed that the surface hydroxyls of FeOOH and FMBO provided active sites for metal complexation. FMBO, with its improved properties, is efficient for removing heavy metals from wastewater.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Physical
Russell J. Wilson, Yue Hui, Andrew K. Whittaker, Chun-Xia Zhao
Summary: A novel biomimetic method for preparing silica nanocapsules loaded with iron oxide nanoparticles is reported in this study, showing excellent stability and drug loading efficiency for drug delivery applications.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Review
Engineering, Chemical
Jesus Roberto Vargas-Ortiz, Carmen Gonzalez, Karen Esquivel
Summary: This review discusses the role, physicochemical properties, potential applications, and toxicological effects of magnetic nanoparticles (MNPs) in complex biological systems. MNPs have been widely used in various industries, leading to increased interactions with biological organisms. However, the full impact of these particles on complex biological systems and the toxicology aspects of their biomedical applications remain unclear, with mixed and inconclusive results. A consolidative framework that considers the physicochemical properties and potential risks of MNPs is necessary for their future manageable applications.
Article
Biochemistry & Molecular Biology
Jaewook Lee, Ji-Heon Lee, Seung-Yeul Lee, Sin A. Park, Jae Hoon Kim, Dajeong Hwang, Kyung A. Kim, Han Sang Kim
Summary: In this study, biocompatible nanomaterials were synthesized using gallic acid (GA) and coated onto iron oxide nanoparticles (IONPs). The GA-IONPs exhibited excellent biocompatibility and antioxidant activity, effectively attenuating exosome secretion induced by H2O2-induced oxidative stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Sathya Ramalingam, Kalarical Janardhanan Sreeram, Jonnalagadda Raghava Rao
Summary: This study explored the interaction mechanism and structural changes in BSA caused by silica nanoparticles with different functional groups, providing insights into the potential of silica nanoparticles for targeted delivery applications. Various techniques were used to evaluate the structural changes induced by the interaction between BSA and silica nanoparticles, highlighting the promising application prospects in cell imaging.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Analytical
Gabriel J. Mattos, Carlos A. R. Salamanca-Neto, Eduardo C. M. Barbosa, Pedro H. C. Camargo, Robert F. H. Dekker, Aneli M. Barbosa-Dekker, Elen R. Sartori
Summary: A photoelectrochemical biosensing strategy was developed for highly sensitive detection of the flavonoid rutin. By integrating hematite decorated with palladium nanoparticles and biocatalysis towards laccase-based reactions, a novel biosensing platform was created, showing good sensitivity, selectivity, repeatability, and storage stability.
Article
Environmental Sciences
Wenlin Zhao, Bozhi Ren, Andrew Hursthouse, Zhenghua Wang
Summary: The study successfully synthesized magnetic nanoadsorption materials with high adsorption capacity and easy separation, characterized by flower-like gamma-Fe2O3 microspheres composed of petal-shaped nanosheets. The material has strong magnetic response for rapid solid-liquid separation under external magnetic field, showing promising potential for treating polluted wastewater.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Environmental Sciences
Ana Carolina de Lima Barizao, Jairo Pinto de Oliveira, Ricardo Franci Goncalves, Servio Tulio Cassini
Summary: Microalgae biomass is a versatile option for various purposes, and magnetic harvesting is a promising low-cost, high-efficiency method that can improve results of other harvesting methods. Detailed approaches involving different nanomaterials and their synthesis, as well as recycling methods, are discussed in this overview of the state of the art of magnetic harvesting method.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Energy & Fuels
Rasha A. Al-husseiny, Sabreen L. Kareem, Ahmed Samir Naje, Shahlaa E. Ebrahim
Summary: In this study, two types of iron oxide nanomaterial (Fe3O4) and nanocomposite (T-Fe3O4) were synthesized from tangerine peel bio-waste and used for adsorption of cefixime (CFX) from aqueous solution. The adsorbents were characterized by various techniques, confirming the mesoporous nano-crystalline structure. The optimal conditions for CFX removal were determined, resulting in high q(e) max values of 41.322 and 56.49 mg g(-1) for Fe3O4 and T-Fe3O4, respectively.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Biotechnology & Applied Microbiology
Hoonsub Kim, Pyung Won Im, Yuanzhe Piao
Summary: Uniform-sized iron oxide nanoparticles were encapsulated inside a silica shell using the reverse microemulsion technique, then transformed into iron nitride through thermal treatment under NH3. The resulting core/shell nanostructures exhibited high uniformity in particle-size distribution. The acid-resistant properties of the iron nitride at silica core/shell nanostructures were significantly higher than the starting iron oxide at silica.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Environmental Sciences
W. Mueller, M. Loh, S. Vardoulakis, H. J. Johnston, S. Steinle, N. Precha, W. Kliengchuay, K. Tantrakarnapa, J. W. Cherrie
ENVIRONMENTAL HEALTH
(2020)
Article
Chemistry, Physical
Elisa Giubilato, Virginia Cazzagon, Monica J. B. Amorim, Magda Blosi, Jacques Bouillard, Hans Bouwmeester, Anna Luisa Costa, Bengt Fadeel, Teresa F. Fernandes, Carlos Fito, Marina Hauser, Antonio Marcomini, Bernd Nowack, Lisa Pizzol, Leagh Powell, Adriele Prina-Mello, Haralambos Sarimveis, Janeck James Scott-Fordsmand, Elena Semenzin, Burkhard Stahlmecke, Vicki Stone, Alexis Vignes, Terry Wilkins, Alex Zabeo, Lang Tran, Danail Hristozov
Article
Nanoscience & Nanotechnology
Rachel Verdon, Suzanne L. Gillies, David M. Brown, Theodore Henry, Lang Tran, Charles R. Tyler, Adriano G. Rossi, Vicki Stone, Helinor J. Johnston
Summary: The study compared responses to different nanomaterials between HL-60 cell line and primary neutrophils, finding a similar pattern of response. Some nanomaterials can stimulate neutrophil activation, but some functions may be compromised in HL-60 cells.
Article
Environmental Sciences
Simon Little, Helinor J. Johnston, Vicki Stone, Teresa F. Fernandes
Summary: The study revealed that silver nanomaterials exhibited toxicity towards freshwater oligochaetes in acute and chronic exposures, with potential alleviation of toxicity by the presence of humic acid in the environment. Titanium dioxide nanomaterials did not show toxicity in aquatic or sediment exposures at high concentrations.
Article
Environmental Sciences
William Mueller, Kraichat Tantrakarnapa, Helinor Jane Johnston, Miranda Loh, Susanne Steinle, Sotiris Vardoulakis, John W. Cherrie
Summary: This study found associations between exposure to air pollution and biomass burning during pregnancy and reduced birth weight and low birth weight. However, the effects differed by trimester and sex, suggesting the need for further investigation in Thailand and other low- and middle-income countries.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2021)
Article
Environmental Sciences
Fiona Murphy, Susan Dekkers, Hedwig Braakhuis, Lan Ma-Hock, Helinor Johnston, Gemma Janer, Luisana di Cristo, Stefania Sabella, Nicklas Raun Jacobsen, Agnes G. Oomen, Andrea Haase, Teresa Fernandes, Vicki Stone
Summary: The development of an Integrated Approach to Testing and Assessment (IATA) aimed to support the grouping of different types of High Aspect Ratio Nanomaterials (HARNs) based on their potential to cause mesothelioma. The approach is hypothesis-driven, linking critical physicochemical descriptors for NFs to defined fate/toxicokinetic and hazard outcomes.
Article
Toxicology
Victor C. Ude, David M. Brown, Vicki Stone, Helinor J. Johnston, Martin Leonard
Summary: The study found that copper oxide nanomaterials induced a range of cellular responses in different cell models, with a responsive expression of HMOX1, IL8, and MT2A at 4 to 12 hours post-exposure. These findings can guide the selection of endpoints, timepoints, and models for future investigations on nanomaterial toxicity in the intestine in vitro.
TOXICOLOGY IN VITRO
(2021)
Article
Chemistry, Multidisciplinary
Luisana Di Cristo, Agnes G. Oomen, Susan Dekkers, Colin Moore, Walter Rocchia, Fiona Murphy, Helinor J. Johnston, Gemma Janer, Andrea Haase, Vicki Stone, Stefania Sabella
Summary: The article presents nine integrated approaches to testing and assessment (IATAs) for grouping ingested nanomaterials, using decision trees and tiered testing strategies to support grouping decisions and indicate implications per group.
Article
Toxicology
Rachel Verdon, Vicki Stone, Fiona Murphy, Emily Christopher, Helinor Johnston, Shareen Doak, Ulla Vogel, Andrea Haase, Ali Kermanizadeh
Summary: The incorporation of nanomaterials in consumer products has proven valuable, but their unique physicochemical properties can pose hazards. Due to the large number of nanomaterials available, risk assessment on an individual basis is not feasible, and alternative methods such as grouping are necessary. A three-tiered testing strategy is proposed to determine the similarity of nanomaterials and understand their effects on DNA.
PARTICLE AND FIBRE TOXICOLOGY
(2022)
Article
Engineering, Biomedical
Abdulkader Masri, David M. M. Brown, David G. E. Smith, Vicki Stone, Helinor J. J. Johnston
Summary: The antibacterial properties of nanomaterials are important in consumer products and infectious disease treatments. Currently, there is a lack of standardized methods for evaluating the antibacterial activity of nanomaterials. By comparing the antibacterial effects of copper oxide nanomaterials on different strains of bacteria using various tests, it was found that the time-kill and OD assays were the most sensitive. Standard operating protocols should be developed for a harmonized assessment of nanomaterials' antibacterial activity.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
Article
Medicine, Research & Experimental
Fiona A. Murphy, Helinor J. Johnston, Susan Dekkers, Eric A. J. Bleeker, Agnes G. Oomen, Teresa F. Fernandes, Kirsten Rasmussen, Paula Jantunen, Hubert Rauscher, Neil Hunt, Luisana di Cristo, Hedwig M. Braakhuis, Andrea Haase, Danail Hristozov, Wendel Wohlleben, Stefania Sabella, Vicki Stone
Summary: Manufacturing and functionalizing materials at the nanoscale has led to the generation of various nanoforms of substances. Testing every unique nanoform for adverse effects is impossible, thus hypothesis-driven grouping and read-across approaches supported by the GRACIOUS Framework are promising alternatives for efficient risk assessment. The framework enables the assessment of similarity between nanoforms, minimizing the need for new testing and aligning with the 3R principles. The template used to generate GRACIOUS grouping hypotheses and the IATAs provide a structured approach for data gathering, facilitating decision-making.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
(2023)
Article
Nanoscience & Nanotechnology
Suzanne Gillies, Rachel Verdon, Vicki Stone, David M. Brown, Theodore Henry, Lang Tran, Carl Tucker, Adriano G. Rossi, Charles R. Tyler, Helinor J. Johnston
Summary: This study used transgenic zebrafish as a model to evaluate the toxicity of nanomaterials by assessing inflammatory responses. The results showed that silver and zinc oxide nanomaterials could induce inflammatory responses in zebrafish, with silver nanomaterials having a stronger effect.
Article
Nanoscience & Nanotechnology
Luisana Di Cristo, Gemma Janer, Susan Dekkers, Matthew Boyles, Anna Giusti, Johannes G. Keller, Wendel Wohlleben, Hedwig Braakhuis, Lan Ma-Hock, Agnes G. Oomen, Andrea Haase, Vicki Stone, Fiona Murphy, Helinor J. Johnston, Stefania Sabella
Summary: This study presents four grouping hypotheses for dermal toxicity of nanoforms (NFs) and develops tailored Integrated Approach to Testing and Assessment (IATA) for each hypothesis. The importance of considering NF dissolution in sweat fluids for dermal exposure is demonstrated. It is expected that these approaches will expedite the risk assessment of dermal toxicity for NFs.
Article
Chemistry, Multidisciplinary
Leagh G. Powell, Cameron Alexander, Vicki Stone, Helinor J. Johnston, Claudia Conte
Summary: Delivering drugs to cancer cells in an effective manner can be challenging. Polymeric nanoparticles (NPs) have shown promise as drug delivery systems that can be targeted to cancer cells. This study aimed to assess the toxicity of polymeric NP delivery systems with and without a redox sensitive element. The results showed that adding a redox responsive element to the NPs can reduce their toxicity, which is important for the development of safer nanomedicines.