Autophagy in toxicology: self-consumption in times of stress and plenty

Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor

(2014) Jinghui Zhao et al.   Autophagy

Autophagy protects renal tubular cells against cyclosporine toxicity

(2014) Nicolas Pallet et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

(2014) Wen-Xing Ding et al.   Autophagy

A dual role of p53 in the control of autophagy

(2014) Ezgi Tasdemir et al.   Autophagy

Involvement of ROS in Curcumin-induced Autophagic Cell Death

(2011) Youn Ju Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study

(2011) S Shen et al.   ONCOGENE

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Cadmium-Induced Autophagy in Rat Kidney: An Early Biomarker of Subtoxic Exposure

(2011) Abderrahman Chargui et al.   TOXICOLOGICAL SCIENCES

Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway

(2010) Li-Hsin Chen et al.   BIOCHEMICAL PHARMACOLOGY

Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy

(2010) Manuel Rieber et al.   CANCER BIOLOGY & THERAPY

Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells

(2010) D M Smith et al.   CELL DEATH AND DIFFERENTIATION

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

Peroxisomes as dynamic organelles: autophagic degradation

(2010) Masahide Oku et al.   FEBS Journal

The role of autophagy in follicular development and atresia in rat granulosa cells

(2010) Jong Yeob Choi et al.   FERTILITY AND STERILITY

LAMP-2-deficient human B cells exhibit altered MHC class II presentation of exogenous antigens

(2010) Victoria L. Crotzer et al.   IMMUNOLOGY

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

(2010) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

HIF-1α-dependent autophagy protects HeLa cells from fenretinide (4-HPR)-induced apoptosis in hypoxia☆

(2010) Xiao-Wen Liu et al.   PHARMACOLOGICAL RESEARCH

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Autophagy involvement in cadmium resistance through induction of multidrug resistance-associated protein and counterbalance of endoplasmic reticulum stress WI38 lung epithelial fibroblast cells

(2010) Sung-Chul Lim et al.   TOXICOLOGY

Autophagy plays an important role in Sunitinib-mediated cell death in H9c2 cardiac muscle cells

(2010) Yuqin Zhao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Autophagy is the predominant process induced by arsenite in human lymphoblastoid cell lines

(2010) Alicia M. Bolt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenite exposure in human lymphoblastoid cell lines induces autophagy and coordinated induction of lysosomal genes

(2010) Alicia M. Bolt et al.   TOXICOLOGY LETTERS

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Cadmium adaptation is regulated by multidrug resistance-associated protein-mediated Akt pathway and metallothionein induction

(2009) Seon-Hee Oh et al.   ARCHIVES OF PHARMACAL RESEARCH

Autophagy maintains cardiac function in the starved adult

(2009) Genzou Takemura et al.   Autophagy

A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses

(2009) Bénédicte F. Py et al.   Autophagy

PARP-1 is involved in autophagy induced by DNA damage

(2009) José Antonio Muñoz-Gámez et al.   Autophagy

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

(2009) E Laane et al.   CELL DEATH AND DIFFERENTIATION

Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila

(2009) Donna Denton et al.   CURRENT BIOLOGY

Hypoxia-induced autophagy: cell death or cell survival?

(2009) Nathalie M Mazure et al.   CURRENT OPINION IN CELL BIOLOGY

The IKK complex contributes to the induction of autophagy

(2009) Alfredo Criollo et al.   EMBO JOURNAL

Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux

(2009) M. Rossi et al.   JOURNAL OF CELL SCIENCE

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

p65/RelA Modulates BECN1 Transcription and Autophagy

(2009) T. Copetti et al.   MOLECULAR AND CELLULAR BIOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Enhanced sensitivity of celecoxib in human glioblastoma cells: Induction of DNA damage leading to p53-dependent G1 cell cycle arrest and autophagy

(2009) Khong Kang et al.   Molecular Cancer

Autophagy Facilitates the Development of Breast Cancer Resistance to the Anti-HER2 Monoclonal Antibody Trastuzumab

(2009) Alejandro Vazquez-Martin et al.   PLoS One

Autophagy is required during cycling hypoxia to lower production of reactive oxygen species

(2009) Kasper M.A. Rouschop et al.   RADIOTHERAPY AND ONCOLOGY

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

(2008) M. Kundu et al.   BLOOD

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

(2008) Y. Li et al.   CANCER RESEARCH

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L

(2008) I Papandreou et al.   CELL DEATH AND DIFFERENTIATION

Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification

(2008) C. Settembre et al.   GENES & DEVELOPMENT

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Functional interaction between FOXO3a and ATM regulates DNA damage response

(2008) Wen-Bin Tsai et al.   NATURE CELL BIOLOGY

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

(2008) Andrea Williams et al.   Nature Chemical Biology

Autophagy Is Essential for Preimplantation Development of Mouse Embryos

(2008) S. Tsukamoto et al.   SCIENCE

Autophagy as an ultrastructural marker of heavy metal toxicity in human cord blood hematopoietic stem cells

(2008) Mario Di Gioacchino et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cell death and autophagy: Cytokines, drugs, and nutritional factors

(2008) Wilfried Bursch et al.   TOXICOLOGY

Suppression of autophagy enhances the cytotoxicity of the DNA-damaging aromatic amine p-anilinoaniline

(2008) Althea Elliott et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulation of macroautophagy by mTOR and Beclin 1 complexes

(2007) Sophie Pattingre et al.   BIOCHIMIE

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

(2007) Kirsteen H. Maclean et al.   JOURNAL OF CLINICAL INVESTIGATION