The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

Integrative DNA, RNA, and Protein Evidence Connects TREML4 to Coronary Artery Calcification

(2014) Shurjo K. Sen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

STAT1 plays a role in TLR signal transduction and inflammatory responses

(2014) Kevin Luu et al.   IMMUNOLOGY AND CELL BIOLOGY

A New Triggering Receptor Expressed on Myeloid Cells (Trem) Family Member, Trem-Like 4, Binds to Dead Cells and Is a DNAX Activation Protein 12-Linked Marker for Subsets of Mouse Macrophages and Dendritic Cells

(2014) H. Hemmi et al.   JOURNAL OF IMMUNOLOGY

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

(2014) G. Kleinberger et al.   Science Translational Medicine

Novel genes detected by transcriptional profiling from whole-blood cells in patients with early onset of acute coronary syndrome

(2013) Vivian N. Silbiger et al.   CLINICA CHIMICA ACTA

TLRs and interferons: a central paradigm in autoimmunity

(2013) Dwight H. Kono et al.   CURRENT OPINION IN IMMUNOLOGY

Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12

(2013) Agnieszka Paradowska-Gorycka et al.   HUMAN IMMUNOLOGY

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

(2013) Zaida G Ramirez-Ortiz et al.   NATURE IMMUNOLOGY

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nucleic Acid Recognition by the Innate Immune System

(2011) Roman Barbalat et al.   Annual Review of Immunology

Treml4, an Ig Superfamily Member, Mediates Presentation of Several Antigens to T Cells In Vivo, Including Protective Immunity to HER2 Protein

(2011) H. Hemmi et al.   JOURNAL OF IMMUNOLOGY

TLR9 Regulates TLR7- and MyD88-Dependent Autoantibody Production and Disease in a Murine Model of Lupus

(2010) Kevin M. Nickerson et al.   JOURNAL OF IMMUNOLOGY

TREM and TREM-like receptors in inflammation and disease

(2009) Jill W Ford et al.   CURRENT OPINION IN IMMUNOLOGY

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

(2009) Elsa-Noah N'Diaye et al.   JOURNAL OF CELL BIOLOGY

TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans

(2009) A. Valance Washington et al.   JOURNAL OF CLINICAL INVESTIGATION

Cross-regulation of signaling by ITAM-associated receptors

(2009) Lionel B Ivashkiv   NATURE IMMUNOLOGY

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

(2008) Laura Piccio et al.   BRAIN

T Cell-Independent and Toll-like Receptor-Dependent Antigen-Driven Activation of Autoreactive B Cells

(2008) Robin A. Herlands et al.   IMMUNITY

IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice

(2008) Donna L. Thibault et al.   JOURNAL OF CLINICAL INVESTIGATION

Highly parallel identification of essential genes in cancer cells

(2008) B. Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA