Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia

B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity

(2014) Jason Qian et al.   CELL

Clonal origins of ETV6-RUNX1+ acute lymphoblastic leukemia: studies in monozygotic twins

(2014) D Alpar et al.   LEUKEMIA

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

(2014) Elli Papaemmanuil et al.   NATURE GENETICS

Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics

(2014) Charles Gawad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny

(2013) S. Kumar et al.   GENES & DEVELOPMENT

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

(2011) Malay Mandal et al.   NATURE IMMUNOLOGY

Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia

(2010) C. M. Bateman et al.   BLOOD

Activation-Induced Cytidine Deaminase Accelerates Clonal Evolution in BCR-ABL1-Driven B-Cell Lineage Acute Lymphoblastic Leukemia

(2010) T. A. Gruber et al.   CANCER RESEARCH

A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia

(2010) K. Y. Urayama et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

BCL6 is critical for the development of a diverse primary B cell repertoire

(2010) Cihangir Duy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

(2010) Arito Yamane et al.   NATURE IMMUNOLOGY

Dicer1 functions as a haploinsufficient tumor suppressor

(2009) M. S. Kumar et al.   GENES & DEVELOPMENT

Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity

(2008) Albert G. Tsai et al.   CELL

Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling

(2008) Kristen Johnson et al.   IMMUNITY

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

(2008) Charles G. Mullighan et al.   NATURE

SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway

(2008) Sebastian Herzog et al.   NATURE IMMUNOLOGY

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

(2008) Rupesh H Amin et al.   NATURE IMMUNOLOGY