Article
Chemistry, Multidisciplinary
Yuya Sato, Kenta Asawa, Tianwei Huang, Makoto Noiri, Naoko Nakamura, Kristina N. Ekdahl, Bo Nilsson, Kazuhiko Ishihara, Yuji Teramura
Summary: The study characterized Tat peptide-conjugated PEG-lipids for surface modification of liposomes, showing that the number of incorporated Tat-PEG-lipid moieties strongly influenced the amount of adsorbed liposomes. Additionally, the introduction of a collagenase-cleavable amino acid sequence allowed for efficient harvesting of adsorbed liposomes from the substrate. Overall, Tat-PEG-lipid was found to be a suitable tool for manipulation of liposomes and cells.
Article
Biophysics
Emanuelle D. Freitas, Rogerio A. Rataglioli, Josephine Oshodi, Marisa M. Beppu
Summary: The coronavirus pandemic has highlighted the importance of bioactive materials in mitigating viral infections. Bioinspired antimicrobial peptides (AMPs) have emerged as suitable building blocks for antimicrobial coatings due to their versatile design and environmentally friendly features. This review discusses the advances and opportunities in using AMPs to create virucidal coatings, including the fundamental characteristics of peptide structure, advances in coating medical devices, and the role of different materials in designing antiviral coatings.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Biophysics
Mariia Svyntkivska, Tomasz Makowski, Roza Pawlowska, Dorota Kregiel, Ele L. de Boer, Ewa Piorkowska
Summary: Novel PEF nonwovens were successfully produced by solution electrospinning and further modification, showing excellent performance. The hydrophilicity of the nonwovens was improved by sodium hydroxide treatment, and silver particles were deposited on the fiber surfaces through two-step modification with compounds and silver ions, exhibiting good antibacterial activity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biochemistry & Molecular Biology
Yu Rao, Jinghong Wang, Huanhuan Wang, Hong Wang, Rong Gu, Jie Shen, Qing Hao, John L. Brash, Hong Chen
Summary: The study demonstrates a new antibacterial agent PGB polymer, which achieves broad-spectrum antibacterial activity and excellent biocompatibility through structural optimization, making it suitable for designing antibacterial surfaces on medical devices.
Article
Environmental Sciences
Camelia Ungureanu, Laura Barbulescu, Cristina Dumitriu, Claudiu Manole, Cristian Pirvu
Summary: In this study, a new material obtained from titanium ingots residue was coated with natural carotenoids having antibacterial properties. The waste material was transformed into nanostructured titanium dioxide surface with photocatalytic and antibacterial properties. The impurities in the titanium scrap were found to improve the properties of the residue surfaces, and the addition of carotenoids enhanced the antibacterial effects of the titanium surface.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Infectious Diseases
Haixin Qin, Hantian Fang, Xiaoling Chen, Lei Wang, Chengbang Ma, Xinping Xi, Tianbao Chen, Chris Shaw, Mei Zhou
Summary: Amphibian skin-derived antimicrobial peptides are gaining increasing attention for their low drug resistance and potential for further bioactivity optimization. This study isolated a novel dermaseptin peptide with antimicrobial and antiproliferative activities, and designed cationicity-enhanced analogues to explore activity enhancement thresholds. The research suggests that improving net charge can enhance bioactivities up to a certain limit, beyond which bioactivities decrease or remain constant.
Article
Chemistry, Multidisciplinary
Ana Margarida Pereira, Diana Gomes, Andre da Costa, Simoni Campos Dias, Margarida Casal, Raul Machado
Summary: The text discusses the use of genetically engineered recombinant protein polymers with antimicrobial peptides for the production of new antimicrobial materials. These polymers demonstrate antimicrobial activity, indicating their potential for the development of advanced antimicrobial materials.
APPLIED SCIENCES-BASEL
(2021)
Article
Biotechnology & Applied Microbiology
Lin Hou, Wei Wang, Mei-Kun Wang, Xue-Song Song
Summary: This study reports a multifunctional composite wound dressing loaded with chitosan-binding bFGF and antimicrobial peptides. The dressing exhibited excellent antibacterial activity, effectively inhibiting the growth of bacteria, and accelerated wound healing. Cell experiments and animal experiments demonstrated the positive effects of the composite dressing on cell growth and tissue repair.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Polymer Science
Pedro Salas-Ambrosio, Antoine Tronnet, Mostafa Badreldin, Luzangel Reyes, Marc Since, Sandra Bourgeade-Delmas, Bruno Dupuy, Pierre Verhaeghe, Colin Bonduelle
Summary: New macromolecular engineering approaches were developed to prepare star-like polypeptoids through ring-opening polymerization. Evaluation of their cytotoxicity on HepG2 human cell line and screening against a variety of Gram-positive and Gram-negative bacteria identified several compounds with both good and selective antimicrobial activity.
Article
Pharmacology & Pharmacy
Mariana Barbosa, Pedro M. Alves, Fabiola Costa, Claudia Monteiro, Paula Parreira, Catia Teixeira, Paula Gomes, Maria Cristina L. Martins
Summary: Surface immobilization of antimicrobial peptides is a promising strategy to prevent biofilm formation on biomaterials. This study demonstrates that direct surface immobilization of Dhvar5 peptide using copper-catalyzed azide-alkyne cycloaddition method improves antimicrobial activity of chitosan ultrathin coatings.
Article
Materials Science, Composites
Xiangming Feng, Qingyi Liu, Jinyun Zheng, Yongkai Xu, Weihua Chen
Summary: By adding the solid cosolvent ethylene carbonate (EC), the conductivity and operating temperature of Poly(ethylene oxide) (PEO) solid electrolyte can be improved significantly. Additionally, overcoming the poor wettability between the electrolyte and the polyolefin separator can be achieved through facile surface modification.
COMPOSITES COMMUNICATIONS
(2022)
Article
Food Science & Technology
Xiaohan Ge, Xueying Huang, Liping Zhou, Yi Wang
Summary: The study investigates the use of active food packaging with antimicrobial compounds to prolong shelf life and improve product quality. Mixing PLA, zein, and PEG to create a composite film enhances water barrier properties and reduces brittleness of the film.
FOOD PACKAGING AND SHELF LIFE
(2022)
Article
Materials Science, Multidisciplinary
Zijiao Zhang, Ni Kou, Weilong Ye, Shuo Wang, Jiaju Lu, Yun Lu, Huiying Liu, Xiumei Wang
Summary: In this study, antimicrobial peptides were self-assembled on gold substrates to form good antibacterial surfaces with stable antibacterial behavior. The grafted AMPs showed potential as a novel therapeutic method for the treatment of implanted biomaterial infections, with good biocompatibility and enhanced bactericidal performance.
Article
Polymer Science
Johan Stanley, Eleftheria Xanthopoulou, Matjaz Finsgar, Lidija Fras Zemljic, Panagiotis A. Klonos, Apostolos Kyritsis, Savvas Koltsakidis, Dimitrios Tzetzis, Dimitra A. Lambropoulou, Diana Baciu, Theodore A. Steriotis, Georgia Charalambopoulou, Dimitrios N. Bikiaris
Summary: Poly(ethylene 2,5-furandicarboxylate) (PEF)-based nanocomposites containing Ce-bioglass, ZnO, and ZrO2 nanoparticles were synthesized via in situ polymerization, and their structures, thermal properties, and antimicrobial abilities were extensively characterized.
Review
Chemistry, Medicinal
Jose Maria Garcia-Beltran, Marta Arizcun, Elena Chaves-Pozo
Summary: Aquaculture production is increasing, but infectious diseases pose a threat. Antimicrobial peptides (AMPs) from photosynthetic marine organisms have potential as alternatives to antibiotics in aquaculture due to their defense mechanisms and additional activities. This study reviews the knowledge about AMPs from photosynthetic marine organisms and evaluates their suitability for aquaculture.
