A unified survival theory of the functioning of the hypocretinergic system

Pontine Reticular Formation (PnO) Administration of Hypocretin-1 Increases PnO GABA Levels and Wakefulness

(2017) Christopher J. Watson et al.   SLEEP

Eszopiclone Prevents Excitotoxicity and Neurodegeneration in the Hippocampus Induced by Experimental Apnea

(2017) Simon J. Fung et al.   SLEEP

The Injection of Hypocretin-1 into the Nucleus Pontis Oralis Induces either Active Sleep or Wakefulness Depending on the Behavioral State when it is Administered

(2017) Mingchu Xi et al.   SLEEP

Motor control during sleep and wakefulness: Clarifying controversies and resolving paradoxes

(2013) Michael H. Chase   SLEEP MEDICINE REVIEWS

Control of cardiovascular variability during undisturbed wake-sleep behavior in hypocretin-deficient mice

(2012) Alessandro Silvani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

What ethologically based models have taught us about the neural systems underlying fear and anxiety

(2012) N.S. Canteras et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Mechanism for Hypocretin-mediated sleep-to-wake transitions

(2012) M. E. Carter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CSF Levels of Hypocretin-1 (Orexin-A) Peak during Early Infancy in Humans

(2012) Adi Aran et al.   SLEEP

Abnormal Sleep-Cardiovascular System Interaction in Narcolepsy with Cataplexy: Effects of Hypocretin Deficiency in Humans

(2012) Daniela Grimaldi et al.   SLEEP

Noradrenergic modulation of wakefulness/arousal

(2012) Craig W. Berridge et al.   SLEEP MEDICINE REVIEWS

Hypothalamus-Olfactory System Crosstalk: Orexin A Immunostaining in Mice

(2012) Jean Gascuel et al.   Frontiers in Neuroanatomy

Evidence for the role of hindbrain orexin-1 receptors in the control of meal size

(2011) Eric M. Parise et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Neuroprotective Effect of Orexin-A Is Mediated by an Increase of Hypoxia-inducible Factor-1 Activity in Rat

(2011) Li-bang Yuan et al.   ANESTHESIOLOGY

Orexin Receptors: Pharmacology and Therapeutic Opportunities

(2011) Thomas E. Scammell et al.   Annual Review of Pharmacology and Toxicology

The periaqueductal gray as a critical site to mediate reward seeking during predatory hunting

(2011) Sandra Regina Mota-Ortiz et al.   BEHAVIOURAL BRAIN RESEARCH

Harnessing neuroplasticity for clinical applications

(2011) S. C. Cramer et al.   BRAIN

Orexin Is Required for Brown Adipose Tissue Development, Differentiation, and Function

(2011) Dyan Sellayah et al.   Cell Metabolism

Orexins and their receptors from fish to mammals: A comparative approach

(2011) Kari K.Y. Wong et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Intracellular energy status regulates activity in hypocretin/orexin neurones: a link between energy and behavioural states

(2011) Zhong-Wu Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Role for Orexin in Central Vestibular Motor Control

(2011) Jun Zhang et al.   NEURON

Orexin microinjection in the medullary raphe increases heart rate and arterial pressure but does not reduce tail skin blood flow in the awake rat

(2011) L.N.L. Luong et al.   NEUROSCIENCE

Hypocretinergic neurons are activated in conjunction with goal-oriented survival-related motor behaviors

(2011) Pablo Torterolo et al.   PHYSIOLOGY & BEHAVIOR

The lateral hypothalamus as integrator of metabolic and environmental needs: From electrical self-stimulation to opto-genetics

(2011) Hans-Rudi Berthoud et al.   PHYSIOLOGY & BEHAVIOR

Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal

(2011) Takeshi Sakurai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Structural dynamics of the cell nucleus

(2011) Gillian Queisser et al.   Nucleus

The orexin system: roles in sleep/wake regulation

(2010) Takeshi Sakurai et al.   Annals of the New York Academy of Sciences

Angiogenic role of orexin-A via the activation of extracellular signal-regulated kinase in endothelial cells

(2010) Mi-Kyoung Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cerebellar Nuclei: Key Roles for Strategically Located Structures

(2010) Mario Manto et al.   CEREBELLUM

HYPOCRETIN DEFICIENCY IN NARCOLEPSY WITH CATAPLEXY IS ASSOCIATED WITH A NORMAL BODY CORE TEMPERATURE MODULATION

(2010) Daniela Grimaldi et al.   CHRONOBIOLOGY INTERNATIONAL

Central chemoreception in wakefulness and sleep: evidence for a distributed network and a role for orexin

(2010) Eugene Nattie et al.   JOURNAL OF APPLIED PHYSIOLOGY

Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins

(2010) H. Schwimmer et al.   JOURNAL OF APPLIED PHYSIOLOGY

Julius H. Comroe, Jr., Distinguished Lecture: Central chemoreception: then … and now

(2010) Eugene Nattie   JOURNAL OF APPLIED PHYSIOLOGY

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

(2010) Feng Zhang et al.   Nature Protocols

The role of orexin-A in food motivation, reward-based feeding behavior and food-induced neuronal activation in rats

(2010) D.L. Choi et al.   NEUROSCIENCE

General Anesthesia, Sleep, and Coma

(2010) Emery N. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Low cerebrospinal fluid and plasma orexin-A (hypocretin-1) concentrations in combat-related posttraumatic stress disorder

(2010) Jeffrey R. Strawn et al.   PSYCHONEUROENDOCRINOLOGY

Interactions of orexins/hypocretins with adrenocortical functions

(2009) S. M. Kagerer et al.   Acta Physiologica

Orexins/hypocretins and orexin receptors in apoptosis: a mini-review

(2009) M. Laburthe et al.   Acta Physiologica

Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction

(2009) Gary Aston-Jones et al.   BRAIN RESEARCH

Orexins Excite Neurons of the Rat Cerebellar Nucleus Interpositus Via Orexin 2 Receptors In Vitro

(2009) Lei Yu et al.   CEREBELLUM

Integrative Physiology of Orexins and Orexin Receptors

(2009) Michihiro Mieda et al.   CNS & Neurological Disorders-Drug Targets

Hypocretin /orexin contributes to the expression of some but not all forms of stress and arousal

(2009) Teri M. Furlong et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

State-dependent control of lumbar motoneurons by the hypocretinergic system

(2009) Jack Yamuy et al.   EXPERIMENTAL NEUROLOGY

Immunohistochemical localization of orexins (hypocretins) in the brain of reptiles and its relation to monoaminergic systems

(2009) Laura Domínguez et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Quantification of Tonic and Phasic Muscle Activity in REM Sleep Behavior Disorder

(2009) Geert Mayer et al.   JOURNAL OF CLINICAL NEUROPHYSIOLOGY

Orexin-A inputs onto visuomotor cell groups in the monkey brainstem

(2009) S. Schreyer et al.   NEUROSCIENCE

The role of the superior colliculus in predatory hunting

(2009) I.C. Furigo et al.   NEUROSCIENCE

Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Reward System

(2009) N. Tsujino et al.   PHARMACOLOGICAL REVIEWS

Dissecting the brain's fear system reveals the hypothalamus is critical for responding in subordinate conspecific intruders

(2009) S. C. Motta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions of orexins in peripheral tissues

(2008) M. V. Heinonen et al.   Acta Physiologica

Modulation of Cortical Activation and Behavioral Arousal by Cholinergic and Orexinergic Systems

(2008) Barbara E. Jones   Annals of the New York Academy of Sciences

Emotional and state-dependent modification of cardiorespiratory function: Role of orexinergic neurons

(2008) Tomoyuki Kuwaki et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Investigation of the hypothalamic defensive system in the mouse

(2008) Raquel C.R. Martinez et al.   BEHAVIOURAL BRAIN RESEARCH

Olfactory dysfunction in patients with narcolepsy with cataplexy is restored by intranasal Orexin A (Hypocretin-1)

(2008) Paul Christian Baier et al.   BRAIN

Human time perception and its illusions

(2008) David M Eagleman   CURRENT OPINION IN NEUROBIOLOGY

Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy

(2008) Massoud Akhtari et al.   EPILEPSIA

Hypothalamic orexins/hypocretins as regulators of breathing

(2008) Rhîannan H. Williams et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism

(2008) Thierry Voisin et al.   FASEB JOURNAL

Relation of Locus Coeruleus Neurons in Monkeys to Pavlovian and Operant Behaviors

(2008) Sebastien Bouret et al.   JOURNAL OF NEUROPHYSIOLOGY

Maternal High-Fat Diet and Fetal Programming: Increased Proliferation of Hypothalamic Peptide-Producing Neurons That Increase Risk for Overeating and Obesity

(2008) G.-Q. Chang et al.   JOURNAL OF NEUROSCIENCE

CSF hypocretin-1 assessment in sleep and neurological disorders

(2008) Patrice Bourgin et al.   LANCET NEUROLOGY

I.c.v. administration of orexin-A induces an antidepressive-like effect through hippocampal cell proliferation

(2008) N. Ito et al.   NEUROSCIENCE

Novel functions of orexigenic hypothalamic peptides: From genes to behavior

(2008) Stephen C. Benoit et al.   NUTRITION

Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglandins, sensory afferent neuropeptides and nitric oxide

(2008) Tomasz Brzozowski et al.   REGULATORY PEPTIDES

Orexin neuronal circuitry: Role in the regulation of sleep and wakefulness

(2007) Kousaku Ohno et al.   FRONTIERS IN NEUROENDOCRINOLOGY