Journal
NATURE GENETICS
Volume 47, Issue 8, Pages 853-855Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.3364
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A major challenge in human genetics is pinpointing which non-coding genetic variants affect gene expression and disease risk. A new study in this issue describes a broadly applicable approach for this task that explicitly models cell type-specific regulatory motifs and generates variant effect predictions that are more accurate and interpretable than those of alternative tools.
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