Isoform diversity in the Arp2/3 complex determines actin filament dynamics

Single-molecule imaging of a three-component ordered actin disassembly mechanism

(2015) Silvia Jansen et al.   Nature Communications

Interactions with Actin Monomers, Actin Filaments, and Arp2/3 Complex Define the Roles of WASP Family Proteins and Cortactin in Coordinately Regulating Branched Actin Networks

(2014) Luke A. Helgeson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural analysis of the transitional state of Arp2/3 complex activation by two actin-bound WCAs

(2014) Malgorzata Boczkowska et al.   Nature Communications

Electron Tomography and Simulation of Baculovirus Actin Comet Tails Support a Tethered Filament Model of Pathogen Propulsion

(2014) Jan Mueller et al.   PLOS BIOLOGY

Arp2/3-Mediated Actin-Based Motility: A Tail of Pathogen Abuse

(2013) Matthew D. Welch et al.   Cell Host & Microbe

WIP Provides an Essential Link between Nck and N-WASP during Arp2/3-Dependent Actin Polymerization

(2013) Sara K. Donnelly et al.   CURRENT BIOLOGY

Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation

(2013) A. C. Humphries et al.   JOURNAL OF CELL SCIENCE

Dimeric WH2 domains in Vibrio VopF promote actin filament barbed-end uncapping and assisted elongation

(2013) Julien Pernier et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP

(2013) Luke A Helgeson et al.   eLife

Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin

(2012) Keefe T. Chan et al.   BIOCHEMICAL JOURNAL

Clathrin Potentiates Vaccinia-Induced Actin Polymerization to Facilitate Viral Spread

(2012) Ashley C. Humphries et al.   Cell Host & Microbe

The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration

(2012) Praveen Suraneni et al.   JOURNAL OF CELL BIOLOGY

Actin branching in the initiation and maintenance of lamellipodia

(2012) M. Vinzenz et al.   JOURNAL OF CELL SCIENCE

Cortactin Releases the Brakes in Actin- Based Motility by Enhancing WASP-VCA Detachment from Arp2/3 Branches

(2011) Orit Siton et al.   CURRENT BIOLOGY

Three-dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors

(2011) Xiao-Ping Xu et al.   EMBO JOURNAL

Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex

(2011) S.-C. Ti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arp2/3 complex is bound and activated by two WASP proteins

(2011) S. B. Padrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unraveling the enigma: progress towards understanding the coronin family of actin regulators

(2011) Keefe T. Chan et al.   TRENDS IN CELL BIOLOGY

Cortactin

(2011) Kellye C. Kirkbride et al.   Cell Adhesion & Migration

Two-color Photoactivatable Probe for Selective Tracking of Proteins and Cells

(2010) Arkadiusz Welman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A nucleator arms race: cellular control of actin assembly

(2010) Kenneth G. Campellone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyond

(2010) Klemens Rottner et al.   TRENDS IN CELL BIOLOGY

The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility

(2009) Ina Weisswange et al.   NATURE

Coronin 1B Antagonizes Cortactin and Remodels Arp2/3-Containing Actin Branches in Lamellipodia

(2008) Liang Cai et al.   CELL

Arp2/3 complex interactions and actin network turnover in lamellipodia

(2008) Frank PL Lai et al.   EMBO JOURNAL

The structural basis of actin filament branching by the Arp2/3 complex

(2008) Isabelle Rouiller et al.   JOURNAL OF CELL BIOLOGY

X-Ray Scattering Study of Activated Arp2/3 Complex with Bound Actin-WCA

(2008) Malgorzata Boczkowska et al.   STRUCTURE