Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis

Human ASPL/TUG interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the ER-associated degradation defect

(2014) Louise Madsen et al.   BMC CELL BIOLOGY

The Intraflagellar Transport Protein IFT27 Promotes BBSome Exit from Cilia through the GTPase ARL6/BBS3

(2014) Gerald M. Liew et al.   DEVELOPMENTAL CELL

IFT27 Links the BBSome to IFT for Maintenance of the Ciliary Signaling Compartment

(2014) Thibaut Eguether et al.   DEVELOPMENTAL CELL

Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators

(2014) Yangfan P. Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

The Membrane Proteome of Sensory Cilia to the Depth of Olfactory Receptors

(2014) Katja Kuhlmann et al.   MOLECULAR & CELLULAR PROTEOMICS

Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extension

(2014) Kousuke Kasahara et al.   Nature Communications

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy

(2014) Koji Yamano et al.   eLife

Assembling a primary cilium

(2013) Sehyun Kim et al.   CURRENT OPINION IN CELL BIOLOGY

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

(2013) Paola Magnaghi et al.   Nature Chemical Biology

Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover

(2013) James A. Olzmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization

(2012) Mallikarjun Patil et al.   CELL CYCLE

Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity

(2012) Alexia Mahuzier et al.   JOURNAL OF CELL BIOLOGY

Control of vertebrate intraflagellar transport by the planar cell polarity effector Fuz

(2012) Eric R. Brooks et al.   JOURNAL OF CELL BIOLOGY

Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology

(2012) Kenta Onoue et al.   JOURNAL OF CELL SCIENCE

CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development

(2012) Chelsea B. Backer et al.   MOLECULAR BIOLOGY OF THE CELL

The BBSome controls IFT assembly and turnaround in cilia

(2012) Qing Wei et al.   NATURE CELL BIOLOGY

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

(2012) Hemmo Meyer et al.   NATURE CELL BIOLOGY

Exploring the Transcriptome of Ciliated Cells Using In Silico Dissection of Human Tissues

(2012) Alexander E. Ivliev et al.   PLoS One

Crystal structure of human FAF1 UBX domain reveals a novel FcisP touch-turn motif in p97/VCP-binding region

(2011) Wonchull Kang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

(2011) Liyun Sang et al.   CELL

Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II

(2011) Rati Verma et al.   MOLECULAR CELL

Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations

(2011) Danilo Ritz et al.   NATURE CELL BIOLOGY

Defining human ERAD networks through an integrative mapping strategy

(2011) John C. Christianson et al.   NATURE CELL BIOLOGY

The Tissue-Specific Rep8/UBXD6 Tethers p97 to the Endoplasmic Reticulum Membrane for Degradation of Misfolded Proteins

(2011) Louise Madsen et al.   PLoS One

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

(2011) T.-F. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hierarchical Binding of Cofactors to the AAA ATPase p97

(2011) Petra Hänzelmann et al.   STRUCTURE

Phosphorylation of p37 is important for Golgi disassembly at mitosis

(2010) Yayoi Kaneko et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Signaling Pathways Regulating Primary Cilium Length and Flow-Mediated Adaptation

(2010) Tatiana Y. Besschetnova et al.   CURRENT BIOLOGY

Imbalances in p97 co-factor interactions in human proteinopathy

(2010) Vanesa Fernández-Sáiz et al.   EMBO REPORTS

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

The ubiquitin conjugation system is involved in the disassembly of cilia and flagella

(2009) Kaiyao Huang et al.   JOURNAL OF CELL BIOLOGY

Intraflagellar Transport (IFT) Protein IFT25 Is a Phosphoprotein Component of IFT Complex B and Physically Interacts with IFT27 in Chlamydomonas

(2009) Zhaohui Wang et al.   PLoS One

Insights into adaptor binding to the AAA protein p97

(2008) Heidi O. Yeung et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

UBXD7 Binds Multiple Ubiquitin Ligases and Implicates p97 in HIF1α Turnover

(2008) Gabriela Alexandru et al.   CELL

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

(2008) C. Schuberth et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY