DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells

(2015) Fabio R. Santori et al.   Cell Metabolism

Involvement of RORγt-overexpressing T cells in the development of autoimmune arthritis in mice

(2015) Yuya Kondo et al.   ARTHRITIS RESEARCH & THERAPY

Regulation of Transcription by Long Noncoding RNAs

(2014) Roberto Bonasio et al.   Annual Review of Genetics

The Transcription Factors T-bet and Runx Are Required for the Ontogeny of Pathogenic Interferon-γ-Producing T Helper 17 Cells

(2014) Yan Wang et al.   IMMUNITY

Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

(2014) Linyan Meng et al.   NATURE

RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

(2014) Eliezer Calo et al.   NATURE

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

(2014) Yi Yang et al.   NATURE

Dissecting noncoding and pathogen RNA–protein interactomes

(2014) Ryan A. Flynn et al.   RNA

Targeting Th17 cells in autoimmune diseases

(2014) Jianfei Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

RNA Helicases DDX5 and DDX17 Dynamically Orchestrate Transcription, miRNA, and Splicing Programs in Cell Differentiation

(2014) Etienne Dardenne et al.   Cell Reports

The NeST Long ncRNA Controls Microbial Susceptibility and Epigenetic Activation of the Interferon-γ Locus

(2013) J. Antonio Gomez et al.   CELL

Profiling of Glucose-Sensing Neurons Reveals that GHRH Neurons Are Activated by Hypoglycemia

(2013) Sarah Stanley et al.   Cell Metabolism

ATP-Dependent roX RNA Remodeling by the Helicase maleless Enables Specific Association of MSL Proteins

(2013) Sylvain Maenner et al.   MOLECULAR CELL

Tandem Stem-Loops in roX RNAs Act Together to Mediate X Chromosome Dosage Compensation in Drosophila

(2013) Ibrahim Avsar Ilik et al.   MOLECULAR CELL

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

(2013) You Jeong Lee et al.   NATURE IMMUNOLOGY

A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes

(2013) S. Carpenter et al.   SCIENCE

GPR15-Mediated Homing Controls Immune Homeostasis in the Large Intestine Mucosa

(2013) S. V. Kim et al.   SCIENCE

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

mrhl RNA, a Long Noncoding RNA, Negatively Regulates Wnt Signaling through Its Protein Partner Ddx5/p68 in Mouse Spermatogonial Cells

(2012) G. Arun et al.   MOLECULAR AND CELLULAR BIOLOGY

The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage

(2012) S M Nicol et al.   ONCOGENE

The natural and the inducible: interleukin (IL)-17-producing γδ T cells

(2012) Yueh-hsiu Chien et al.   TRENDS IN IMMUNOLOGY

Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors

(2012) Jun R. Huh et al.   ACS Medicinal Chemistry Letters

RNA helicases p68 and p72: multifunctional proteins with important implications for cancer development

(2011) Frances V Fuller-Pace et al.   Future Oncology

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions

(2011) Ci Chu et al.   MOLECULAR CELL

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

(2011) Jun R. Huh et al.   NATURE

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RMRP Is a Non-Coding RNA Essential for Early Murine Development

(2011) Joseph Rosenbluh et al.   PLoS One

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Of proteins and RNA: The RNase P/MRP family

(2010) O. Esakova et al.   RNA

Nuclear Receptor Coregulators in Cancer Biology

(2009) B. W. O'Malley et al.   CANCER RESEARCH

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Prolonged Impact of Antibiotics on Intestinal Microbial Ecology and Susceptibility to Enteric Salmonella Infection

(2009) A. Croswell et al.   INFECTION AND IMMUNITY

The DEAD-box protein p72 regulates ERα-/oestrogen-dependent transcription and cell growth and is associated with improved survival in ERα-positive breast cancer

(2009) N C Wortham et al.   ONCOGENE

Autoimmune hypoparathyroidism in a 12-year-old girl with McKusick cartilage hair hypoplasia

(2009) Justine Bacchetta et al.   PEDIATRIC NEPHROLOGY

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

(2008) Dmitry V. Ostanin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The RNA Helicase p68 Is a Novel Androgen Receptor Coactivator Involved in Splicing and Is Overexpressed in Prostate Cancer

(2008) E. L. Clark et al.   CANCER RESEARCH

RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F

(2008) Moritz Leppkes et al.   GASTROENTEROLOGY

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

(2008) Hiroaki Takatori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin

(2008) Carmelo Luci et al.   NATURE IMMUNOLOGY

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation

(2007) Eric D. Jensen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY