Review
Agronomy
Kasinathan Rakkammal, Theivanayagam Maharajan, Stanislaus Antony Ceasar, Manikandan Ramesh
Summary: Biostimulants are products that reduce fertilizer requirements, stimulate plant growth, and protect crops from abiotic stress by increasing tolerance. They have various effects on plant growth, including promoting growth, enhancing nutrient absorption and utilization, increasing photosynthetic activity, and improving tolerance to biotic and abiotic stressors.
CEREAL RESEARCH COMMUNICATIONS
(2023)
Article
Engineering, Chemical
Prabu Baskar, Periyasamy Rathinapriya, Mayakrishnan Prabakaran
Summary: This study reports the use of Trochodendron aralioides extract as a cost-effective and environmentally friendly corrosion inhibitor in a 1M HCl medium. The results showed that the inhibitory efficiency increased with increasing concentration of the extract. The plant extract was found to form a protective film on the surface of the specimens, enhancing the inhibition and reducing corrosion.
Review
Biology
Pandiyan Muthuramalingam, Rajendran Jeyasri, Kasinathan Rakkammal, Lakkakula Satish, Sasanala Shamili, Adhimoolam Karthikeyan, Alaguvel Valliammai, Arumugam Priya, Anthonymuthu Selvaraj, Pandiyan Gowri, Qiang-Sheng Wu, Shunmugiah Karutha Pandian, Hyunsuk Shin, Jen-Tsung Chen, Venkidasamy Baskar, Muthu Thiruvengadam, Manoharan Akilan, Manikandan Ramesh
Summary: Rice is an important food crop in Asian countries, but its growth and yield are affected by salinity stress. Understanding the mechanisms of salinity stress and developing salinity-tolerant rice varieties are crucial for future food security. This review discusses the use of high-throughput technologies and multi-omics approaches to study salinity stress in rice and highlights the potential ways to enhance salt tolerance and develop salt-tolerant varieties. The review also emphasizes the importance of incorporating the latest advancements and knowledge in plant stress biology to further understand the mechanisms of salinity stress in rice.
Review
Plant Sciences
Theivanayagam Maharajan, T. P. Ajeesh Krishna, Kasinathan Rakkammal, Stanislaus Antony Ceasar, Manikandan Ramesh
Summary: Application of CRISPR/Cas tools can enhance cereals' growth and yield under biotic and abiotic stresses. However, studies on the mechanism of biotic and abiotic stress tolerance in cereals using the CRISPR/Cas system are limited. Rice is the most studied cereal in this aspect, while other major cereals have not been extensively explored. Understanding the role of specific genes in response to stresses through the CRISPR/Cas system may help improve cereals' growth and yield under various stress conditions.
Review
Polymer Science
M. Rama, U. Vijayalakshmi
Summary: Human osteology is the study of the minerals and non-collagenous organic components in human bones that protect organs and aid in blood cell production. Bone defects often require the use of biomaterial matrices and bioactive signaling molecules to promote regenerative healing. This review focuses on the development of drug delivery systems and their interaction with scaffolding surfaces in bone tissue engineering, as well as potential strategies for controlling bone-related infections.
Article
Multidisciplinary Sciences
Murali Aarthy, Pandiyan Muthuramalingam, Manikandan Ramesh, Sanjeev Kumar Singh
Summary: A molecular-level understanding of how viral infections cause cervical cancer is crucial for the development of effective treatments. Systems pharmacology and multi-omics approaches have been used to investigate the mechanisms of biologically active compounds against cervical cancer. The study identified immune genes that play a significant role in cervical cancer, and found that certain compounds from medicinal plants target these genes. The findings provide potential therapeutic targets for cervical cancer caused by HPV and suggest that the identified compounds could be used as anti-HPV drugs.
SCIENTIFIC REPORTS
(2022)
Review
Plant Sciences
Kasinathan Rakkammal, Arumugam Priya, Subramani Pandian, Theivanayagam Maharajan, Periyasamy Rathinapriya, Lakkakula Satish, Stanislaus Antony Ceasar, Soo-In Sohn, Manikandan Ramesh
Summary: Cereals have developed various tolerance mechanisms to cope with abiotic stress. The omics field, including genomics, transcriptomics, and proteomics, has made significant progress in understanding these mechanisms. Integrated omics and bioinformatics approaches are crucial for studying genome-wide stress-regulation mechanisms.
Article
Biochemistry & Molecular Biology
Shaily Tyagi, Maniraj Rathinam, Narasimham Dokka, Nidhee Chaudhary, Lakkakula Satish, Prasanta K. K. Dash, Ajit Kumar Shasany, Rohini Sreevathsa
Summary: This study identified a gene CpF3 ' 5 ' H_2 from a wild relative of pigeonpea that showed a robust chemical resistance response to the pod borer Helicoverpa armigera. Transgenic tobacco overexpressing the CpF3 ' 5 ' H_2 gene exhibited reduced leaf damage and increased larval mortality, suggesting its potential role in the management of H. armigera.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agronomy
Theivanayagam Maharajan, Thumadath Palayullaparambil Ajeesh Krishna, Kasinathan Rakkammal, Muthusamy Ramakrishnan, Stanislaus Antony Ceasar, Manikandan Ramesh, Savarimuthu Ignacimuthu
Summary: This study identified quantitative trait loci (QTL) for various agro-morphological and phosphorus-content traits in finger millet under low phosphorus (LP) and high phosphorus (HP) conditions using linkage mapping. A total of 55 QTL associated with agro-morphological and phosphorus-content traits were detected under LP conditions, and 37 QTL were detected under HP conditions. Biotic and abiotic stress-responsive candidate genes linked to some of the QTL were also identified. These findings can be utilized in breeding programs to develop finger millet with better phosphorus use efficiency and improve the lives of poor farmers.
Review
Biotechnology & Applied Microbiology
Rajendran Jeyasri, Pandiyan Muthuramalingam, Kannan Karthick, Hyunsuk Shin, Sung Hwan Choi, Manikandan Ramesh
Summary: Plant secondary metabolites are crucial for plant survival and defense mechanism, and have a wide variety of therapeutic values for humans. Due to their affordability and vital role in traditional remedies, medicinal plants are widely exploited, leading to their threat. Elicitation, using biotic and abiotic elicitors, can be employed to enhance the levels of bioactive compounds. This comprehensive review provides an overview of elicitation strategies and their effects on medicinal plants, serving as a significant groundwork for researchers in the field.
PLANT CELL TISSUE AND ORGAN CULTURE
(2023)
Article
Plant Sciences
Kasinathan Rakkammal, Theivanayagam Maharajan, R. N. Shriram, P. S. Jeevan Ram, Stanislaus Antony Ceasar, Manikandan Ramesh
Summary: Drought is a dangerous abiotic stress that negatively affects the growth, development, and yield of major cereals like finger millet. This study conducted physiological and molecular analyses to examine the responses of ten finger millet genotypes to drought. The results showed that drought significantly reduced the physiological traits of the genotypes, but the tolerant genotype (IC 87469) exhibited higher chlorophyll pigment contents, antioxidant enzyme activities, and proline accumulation compared to the susceptible genotype (IC 49940). The study also identified and analyzed four classical drought-responsive genes from the finger millet genome sequence. These findings provide valuable insights for future biotechnological approaches to improve drought tolerance in finger millet.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Infectious Diseases
Sarath Praseetha, Swapna Thacheril Sukumaran, Mathew Dan, Akshaya Rani Augustus, Shunmugiah Karutha Pandian, Shiburaj Sugathan
Summary: This study found that the essential oil extracted from the plant Hedychium larsenii has potential anti-biofilm and anti-virulence effects against Streptococcus pyogenes. Linalool, a compound in the oil, showed concentration-dependent inhibition of biofilm formation. Linalool treatment also affected the expression of genes associated with virulence and biofilm formation.
Article
Biotechnology & Applied Microbiology
Arunachalam Kannappan, Ravi Jothi, Xiaorong Tian, Shunmugiah Karutha Pandian, Shanmugaraj Gowrishankar, Shi Chunlei
Summary: This study reveals the antibacterial efficacy of 2-hydroxy-4-methoxybenzaldehyde (HMB) isolated from Hemidesmus indicus against Staphylococcus aureus. HMB inhibits bacterial growth, disrupts cell membrane, and eradicates preformed biofilms. Furthermore, HMB enhances the sensitivity of MRSA cells to tetracycline, indicating its potential as a lead structure for developing new antibacterial drugs.
JOURNAL OF APPLIED MICROBIOLOGY
(2023)
Article
Environmental Sciences
Ravi Jothi, Ravichellam Sangavi, Veerapandian Raja, Ponnuchamy Kumar, Shunmugiah Karutha Pandian, Shanmugaraj Gowrishankar
Summary: The present study investigated the antifungal efficacy and action mechanism of the QAS cetyltrimethylammonium chloride (CTAC) against three clinically important Candida species. CTAC exhibited phenomenal antifungal activity against all tested Candida spp., and its effectiveness was not mediated via oxidative stress. CTAC also showed potential as a disinfectant for Candida-associated healthcare infections.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)