Article
Polymer Science
Nidambur Vasudev Ballal, Amal Roy, Matthias Zehnder
Summary: This study evaluated the impact of root canal wall conditioning on the adhesion of different root canal sealers, finding that the use of NaOCl with HEDP was beneficial for both types of sealers. The adhesion of the epoxy resin sealer was negatively affected by NaOCl deproteinization in a dose-dependent manner, while the CaSi sealer showed the opposite effect.
Article
Medicine, General & Internal
Nuha S. Alghamdi, Youssef A. Algarni, Tasneem Sakinatul Ain, Haifa M. Alfaifi, Alaa A. AlQarni, Jamilah Q. Mashyakhi, Sara E. Alasmari, Muhanned M. Alshahrani
Summary: Endodontic mishaps, especially related to obturation, are common during root canal treatment performed by undergraduate dental students, with a higher frequency among level 9 students. The study highlights the importance of guidance for students, particularly during root canal obturation.
Review
Infectious Diseases
Dirk-Joachim Drews, Anh Duc Nguyen, Antje Diederich, Christian Ralf Gernhardt
Summary: In recent years, sodium hypochlorite and chlorhexidine digluconate have been widely used as irrigation solutions in root canal treatments. However, it has been found that the consecutive application of these two solutions can lead to the formation of a potentially harmful precipitate. This article reviews the literature on the interaction between sodium hypochlorite and chlorhexidine digluconate, discusses the effects of the precipitate formed during root canal treatment, and provides alternative irrigation solutions that do not interact with these chemicals.
Article
Chemistry, Multidisciplinary
Ali A. Assiry, Mohmed Isaqali Karobari, Galvin Sim Siang Lin, Rumesa Batul, Niher Tabassum Snigdha, Alexander Maniangat Luke, Krishna Prasad Shetty, Giuseppe Alessandro Scardina, Tahir Yusuf Noorani
Summary: This study analyzed new root canal sealers using techniques such as Fourier transform infrared spectroscopy and scanning electron microscopy. The results showed that these sealers had diverse surface morphologies, consisting of irregular micro-sized particles, and they lacked heavy metals. The main components of these sealers were calcium, oxygen, and carbon.
APPLIED SCIENCES-BASEL
(2023)
Article
Multidisciplinary Sciences
Rafaela Fernandes Zancan, Mohammed Hadis, David Burgess, Zhenyu Jason Zhang, Alessandro Di Maio, Phillip Tomson, Marco Antonio Hungaro Duarte, Josette Camilleri
Summary: This study investigated the impact of irrigating solutions on dentin and the optimal irrigation-obturation strategy for root canal treatment. Results showed that hydraulic calcium silicate cement sealers did not rely on chelator irrigating solutions for good material adaptation to dentin.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, Research & Experimental
Gisele Jung Franciscatto, Giampiero Rossi-Fedele, Manuela Favarin Santini, Mariana de Carlo Bello, Mineia Weber Blattes, Carlos Alexandre Souza Bier
Summary: This study compared the impact of a final rinse with EDTA or CA with and without PUI on the sealing ability of root canal fillings. Results showed that PUI groups had lower infiltration values compared to non-PUI groups, with EDTA demonstrating less glucose infiltration than CA. The use of EDTA or CA with PUI enhanced the sealing of root canal fillings.
INVESTIGACION CLINICA
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mehdi Dastorani, Behnam Malekpour, Mohsen AminSobhani, Mohammadsadegh Alemrajabi, Arezoo Mahdian, Behrooz Malekpour
Summary: This study assessed bacterial microleakage of different sealers under different pressure conditions, finding that the single-cone obturation technique using nano-MTA as a sealer had lower resistance to bacterial microleakage, and pressure changes in simulated underwater diving and aviation conditions did not significantly affect bacterial microleakage.
Article
Polymer Science
Ruan Ferreira Sampaio, Ceci Nunes Carvalho, Vivian Bradaschia-Correa, Bruna Lais Lins Goncalves, Victor Arana-Chavez, Alexandre P. Lima de Carvalho, Amanda Palmeira Arruda Nogueira, Renata Grazziotin-Soares, Jose Bauer, Giulio Gavini, Edilausson Moreno Carvalho
Summary: This study evaluated the apical sealing ability and bioactivity of an experimental gutta-percha containing niobium phosphate bioglass. The results showed that the gutta-percha containing niobophosphate bioglass demonstrated a similar apical sealing ability to the bioceramic gutta-percha and exhibited bioactivity by depositing hydroxyapatite on the surface of the material in simulated body fluid.
Article
Dentistry, Oral Surgery & Medicine
Miriam Zaccaro Scelza, Natalia L. P. P. Iorio, Pantaleo Scelza, Helvecio C. C. Povoa, Caroline S. R. Adeodato, Ana Carolina N. Souza, Ana Carolina Batista, Sandro Tavares, Gutemberg Alves
Summary: This study evaluated the antibacterial ability and cytocompatibility of a new irrigant solution consisting of 10% citric acid and 1% chlorhexidine for endodontic treatment. The results showed that the solution was cytocompatible with human periodontal ligament fibroblasts and had comparable antibacterial activity to other commonly used irrigants. The combination of 10% citric acid and 1% chlorhexidine showed potential as a solution for microbiological control during endodontic treatment.
JOURNAL OF DENTISTRY
(2022)
Article
Chemistry, Physical
Sandro Tavares, Andrea Pintor, Carlos Fernando de Almeida Barros Mourao, Marcela Magno, Pietro Montemezzi, Roberto Sacco, Gutemberg Alves, Miriam Zaccaro Scelza
Summary: This review compared the release of growth factors using different root canal irrigant solutions and found that 10% EDTA showed higher levels of TGF-1 release compared to 10% citric acid. However, the evidence certainty was identified as low to very low, demanding further studies before EDTA can be recommended as a better irrigant for regenerative endodontics.
Article
Dentistry, Oral Surgery & Medicine
Nancy Kudsy Carvalho, Ana Flavia Almeida Barbosa, Barbara de Paula Coelho, Lucio de Souza Goncalves, Luciana Moura Sassone, Emmanuel Joao Nogueira Leal Silva
Summary: The study demonstrates that incorporation of chlorhexidine-hexametaphosphate nanoparticles can enhance the antimicrobial performance of endodontic sealers without impairing other biological and physicochemical properties.
Article
Chemistry, Multidisciplinary
Keerthika Rajamanickam, Kavalipurapu Venkata Teja, Sindhu Ramesh, Sahil Choudhari, Mariangela Cernera, Niccolo Giuseppe Armogida, Mohammed Mustafa, Gianrico Spagnuolo
Summary: This study aimed to evaluate the canal cleanliness using a novel irrigation device with ultrasonic and manual irrigation in extracted teeth. The results showed that passive ultrasonic irrigation significantly reduced the smear layer and debris scores in the root canal compared to the other two methods.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Multidisciplinary
Svetlana Razumova, Anzhela Brago, Dimitriy Serebrov, Haydar Barakat, Yuliya Kozlova, Ammar Howijieh, Zoya Guryeva, Yulianna Enina, Vasiliy Troitskiy
Summary: This study aimed to evaluate the penetration and fixation of nano-silver solution on the dentinal surface during endodontic treatment. The results showed that the 1-2nm nano-silver solution could be fixed on dentin with a removed and preserved smear layer and leave a film on the dentinal surface.
Review
Chemistry, Physical
Germain Sfeir, Carla Zogheib, Shanon Patel, Thomas Giraud, Venkateshbabu Nagendrababu, Frederic Bukiet
Summary: Calcium silicate-based materials have gained popularity as root canal sealers due to their biocompatibility, antimicrobial properties, and certain bioactivity, but their higher solubility may impact their long-term sealing ability. Unlike conventional sealers, these sealers are hydraulic and require humidity for setting. Limited research has been conducted on the clinical outcomes of calcium silicate-based sealers, with current usage mainly based on clinical practices rather than recommendations or evidence.
Article
Chemistry, Physical
Abhishek Isaac Mathew, Silvia Chamin Lee, Giampiero Rossi-Fedele, George Bogen, Venkateshbabu Nagendrababu, William Nguyen Ha
Summary: This study compared the density and radiopacity of mineral trioxide aggregate (MTA) used as a root canal filling material with different compaction techniques. The Lawaty technique group demonstrated the highest mass and radiopacity but required more time for obturation.
Article
Dentistry, Oral Surgery & Medicine
Marlos Barbosa-Ribeiro, Rodrigo Arruda-Vasconcelos, Lidiane M. Louzada, Danielle G. dos Santos, Fernando D. Andreote, Brenda P. F. A. Gomes
Summary: The study found that the microbiota of teeth with endodontic treatment failure is polymicrobial, with Enterococcus faecalis and Porphyromonas gingivalis predominating in all phases of retreatment. Specific bacteria were associated with certain clinical and radiographic features.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
R. Arruda-Vasconcelos, L. M. Louzada, M. Feres, P. L. Tomson, P. R. Cooper, B. P. F. A. Gomes
Summary: The microbial profile, and levels of endotoxin (LPS) and lipoteichoic acid (LTA), in infected dentine and root canals of teeth with irreversible pulpitis were investigated. Root canal preparation effectively reduced the levels of bacteria, LPS and LTA, while intracanal medication did not significantly reduce bacterial levels but led to a significant decrease in LTA levels.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
J. D. Bronzato, M. E. S. Davidian, M. de Castro, A. De-Jesus-Soares, C. C. R. Ferraz, J. F. A. Almeida, M. A. Marciano, B. P. F. A. Gomes
Summary: The study identified a diverse microbial composition in periapical lesions, regardless of the type of root canal treatment. Levels of LPS and LTA in periapical lesions were associated with clinical symptoms, but no specific bacteria were linked to clinical features.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Priscila Amanda Francisco, Pedro Ivo da Graca Fagundes, Joao Carlos Lemes-Junior, Augusto Rodrigues Lima, Maicon Ricardo Zieberg Passini, Brenda P. F. A. Gomes
Summary: The study evaluated Enterococcus faecalis strains isolated from endodontic failures for the presence of virulence genes, biofilm formation capacity, and activity of gelatinase and beta-lactamase. Results showed diverse patterns of virulence gene detection among the strains, with most capable of forming biofilm. Some strains exhibited gelatinase production, while beta-lactamase resistance was detected in different isolates.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
T. B. M. Antunes, A. C. P. Janini, L. E. Pelepenko, G. F. Abuna, E. M. Paiva, M. A. C. Sinhoreti, I. M. Raimundo, B. P. F. A. Gomes, A. de-Jesus-Soares, M. A. Marciano
Summary: The study evaluated modifications in root canal sealers under different heating conditions using vibrational spectroscopy and chemical analysis. Heating significantly changed the flowability and solubility of calcium silicate-based sealers, with AH Plus being the only stable sealer after heating. Calcium silicate-based sealers exhibited high solubility, raising concerns for their clinical use.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Review
Dentistry, Oral Surgery & Medicine
Juliana D. Bronzato, Rafael A. Bomfim, Giovanna Z. P. Hayasida, Mariana Curi, Carlos Estrela, Bruce J. Paster, Brenda P. F. A. Gomes
Summary: The study systematically reviewed the literature on the prevalence of microorganisms in endodontic periapical lesions and found that the prevalence was high, with 87% of lesions containing microorganisms. The prevalence of viable/active microorganisms was slightly lower at 82%. Different geographic areas showed statistical differences, as did viable bacteria compared to active viruses. The most common detection method for microorganisms was molecular, with Actinomyces, Fusobacterium, and Prevotella being the most prevalent bacteria.
ARCHIVES OF ORAL BIOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Brenda P. F. A. Gomes, Juliana D. Bronzato, Rebecca F. Almeida-Gomes, Ericka T. Pinheiro, Ezilmara L. R. Sousa, Rogerio C. Jacinto
Summary: This study evaluated the presence of Fusobacterium nucleatum in primary and secondary endodontic infections in a Brazilian population using both culture and nested PCR methods. The results showed a higher detection rate of F. nucleatum in primary infections compared to secondary ones, with nested PCR method detecting a higher prevalence. The presence of F. nucleatum was associated with various clinical features in root canals.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Rodrigo Arruda-Vasconcelos, Marlos Barbosa-Ribeiro, Lidiane M. Louzada, Beatriz I. N. Lemos, Adriana de-Jesus-Soares, Caio C. R. Ferraz, Jose F. A. Almeida, Marina A. Marciano, Brenda P. F. A. Gomes
Summary: This study aimed to monitor the effects of chemomechanical preparation and intracanal medication on the levels of bacteria, endotoxins, and lipoteichoic acid in teeth with symptomatic irreversible pulpitis. The results showed that chemomechanical preparation and intracanal medication effectively reduced the microbial load and levels of endotoxins and lipoteichoic acid in the root canals of the affected teeth.
JOURNAL OF ENDODONTICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Brenda P. F. A. Gomes, Vanessa B. Berber, Ariane C. S. Marinho, Lidiane M. Louzada, Rodrigo Arruda-Vasconcelos, Maicon R. Z. Passini, Erica M. Lopes, Vanessa G. A. Pecorari, Tsute Chen, Bruce J. Paster
Summary: The study compared the microbiomes, levels of LPS, LTA, and cytokines before and after chemomechanical preparation of the root canals in teeth with combined EPL. Results showed that CMP effectively reduced microbial load and LPS levels, leading to decreased cytokine levels in both the root canals and periodontal pockets.
JOURNAL OF PERIODONTAL RESEARCH
(2022)
Article
Electrochemistry
Jessica Luzardo, Danielle Aguiar, Alexander Silva, Sanair Oliveira, Braulio Archanjo, Renata Simao, Joyce Araujo
Summary: In the study of enzyme immobilization, two different graphene oxide papers were used to immobilize beta-galactosidase, with electrochemical synthesis (EG) paper showing more efficient enzyme immobilization. Cyclic voltammetry analysis indicated that enzymes immobilized on GO paper exhibited improved beta-galactose activity compared to free enzyme solution and enzyme immobilized on a glassy carbon electrode.
JOURNAL OF ELECTROCHEMICAL SCIENCE AND ENGINEERING
(2022)
Review
Dentistry, Oral Surgery & Medicine
Maarten A. Meire, Juliana D. Bronzato, Rafael A. Bomfim, Brenda P. F. A. Gomes
Summary: This systematic review analyzed the effectiveness of adjunct therapy for apical periodontitis in permanent teeth, but there is currently insufficient evidence to recommend any specific adjunct therapy.
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Article
Chemistry, Physical
Douglas Rocha, Jessica Luzardo, Daniele Aguiar, Sanair Massafra, Rogerio Valaski, Alexander Silva, Erlon Ferreira, Renata Simao, Braulio Archanjo, Alexei Kuznetsov, Joyce Araujo
Summary: A new approach to synthesize lignin-derived nanocarbon crystals based on lignin depolymerization is proposed in this study. The chemical structure of lignin was modified using a controlled routine involving UV light irradiation, hydrothermal carbonization, vacuum degassing, pyrolysis, and mechanical exfoliation. This method resulted in a lignin-based nanocarbon with a nanoporous framework structure and oxygenated functional groups. The catalyst-free route used in this study showed high nanocarbon yields and is an eco-friendly strategy for synthesizing low-cost carbon materials. The characterization of the lignin-derived nanocarbon included X-ray diffraction, infrared, Raman, and X-ray photoelectron spectroscopies, as well as scanning and transmission electron microscopy. The developed transformation method has the potential to provide large amounts of carbon-based materials for industrial applications, and it can be adapted to various biomass feedstocks with suitable aromatic groups for high yield polycondensation. The achieved nano-carbon yield ranged from 50 wt% to 70 wt% when starting from a commercial purified lignin.
Review
Dentistry, Oral Surgery & Medicine
Lucas Peixoto de Araujo, Leandro Bueno Gobbo, Tamares Andrade da Silva, Wellington Luiz de Oliveira da Rosa, Jose Flavio Affonso de Almeida, Brenda P. F. A. Gomes, Caio Cezar Randi Ferraz
Summary: The aim of this study was to evaluate the efficacy of supplementary photodynamic therapy (PDT) on primary tooth pulpectomy through a systematic review. Four studies met the inclusion criteria, but no significant conclusions could be drawn due to the moderate-to-low certainty of the available evidence.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2023)
Article
Oncology
Esdras Gabriel Alves-Silva, Rodrigo Arruda-Vasconcelos, Lidiane Mendes Louzada, Adriana de-Jesus-Soares, Caio Cezar Randi Ferraz, Jose Flavio Affonso Almeida, Marina Angelica Marciano, Carolina Steiner-Oliveira, Joao Miguel Marques Santos, Brenda P. F. A. Gomes
Summary: This study evaluated the effectiveness of supplemental photodynamic therapy (aPDT) in improving bacterial removal and reducing the levels of lipopolysaccharide (LPS) and lipoteichoic acid (LTA) in root canals. The results showed that aPDT significantly decreased bacterial counts and levels of LPS and LTA.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2023)
Article
Polymer Science
Isabella de Almeida Guimaraes Passos, Juliana das Neves Marques, Joao Victor Frazao Camara, Renata Antoun Simao, Maira do Prado, Gisele Damiana da Silveira Pereira
Summary: This study evaluated the influence of non-thermal argon plasma on dentin and found that the shear strength significantly increased when dentin was treated with plasma, regardless of the application time.
POLIMEROS-CIENCIA E TECNOLOGIA
(2022)
