Journal
JOURNAL OF APPLIED ORAL SCIENCE
Volume 17, Issue 1, Pages 1-7Publisher
UNIV SAO PAULO FAC ODONTOLOGIA BAURU
DOI: 10.1590/S1678-77572009000100002
Keywords
Biofilm; Intracanal medicaments; Antimicrobial efficacy
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The purpose of this paper is to discuss critically the antibacterial efficacy of intracanal medicaments on bacterial biofilm. Longitudinal studies were evaluated by a systematic review of English-language articles retrieved from electronic biomedical journal databases ( MEDLINE, EMBASE, CENTRAL) and handsearching records, using different matches of keywords for root canal biofilm, between 1966 and August 1(st), 2007. The selected articles were identified from titles, abstracts and full-text articles by two independent reviewers, considering the tabulated inclusion and exclusion criteria. Disagreements were resolved by consensus. The search retrieved 91 related articles, of which 8.8% referred to in vivo studies demonstrating the lack of efficacy of endodontic therapy on bacterial biofilm. Intracanal medicaments were found to have a limited action against bacterial biofilm.
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