Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer’s

Altered apolipoprotein E glycosylation is associated with Aβ(42) accumulation in an animal model of Niemann-Pick Type C disease

(2010) Ching-Ching Chua et al.   JOURNAL OF NEUROCHEMISTRY

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Decreased Npc1 Gene Dosage in Mice Is Associated With Weight Gain

(2009) David Jelinek et al.   Obesity

Intracerebroventricular amyloid-  antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice

(2009) D. R. Thakker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of cholesterol level upon APP and BACE proximity and APP cleavage

(2008) Christine A.F. von Arnim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

(2008) Emyr Lloyd-Evans et al.   NATURE MEDICINE

Variation in NPC1, the gene encoding Niemann–Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population

(2008) Robert P. Erickson et al.   NEUROSCIENCE LETTERS

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE