Journal
NATURAL PRODUCT RESEARCH
Volume 30, Issue 1, Pages 7-12Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1026340
Keywords
Brevibacterium sp; L-4; coral derived endophytic bacteria; tetrapeptide; 3-ylidene-2; 5-piperazinediones
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Funding
- National Natural Science Foundation of China [81001370]
- Collaborative Fund of marine Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences [LMB101002]
- Special Funds from Central Finance of China in Support of the Development of Local Colleges and University [276(2014)]
- Natural Science Foundation of Guangdong Province [2014A030313411]
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One new cyclic tetrapeptide cyclic-(Tyr-Ala-Leu-Ser) (1) along with four natural compounds firstly obtained 3H-imidazole-4-carboxylic acid (2), 2-methyl-3H-imidazole-4-carboxylic acid (3), 3-ethylidene-6-isopropyl-piperazine-2,5-dione (4), and 3-isobutylidene-6-methyl piperazine-2,5-dione (5) have been isolated from the coral derived endophytic bacteria Brevibacterium sp. L-4 collected from the South China Sea. Their structures were elucidated through spectroscopic techniques including NMR (1D and 2D), MS, and EA, and their relative configurations were also assigned by NMR analysis.
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