In vitro activities of the novel bicyclolides modithromycin (EDP-420, EP-013420, S-013420) and EDP-322 against MDR clinical Neisseria gonorrhoeae isolates and international reference strains

First Three Neisseria gonorrhoeae Isolates with High-Level Resistance to Azithromycin in Sweden: a Threat to Currently Available Dual-Antimicrobial Regimens for Treatment of Gonorrhea?

(2013) Magnus Unemo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

2012 European guideline on the diagnosis and treatment of gonorrhoea in adults

(2013) C Bignell et al.   INTERNATIONAL JOURNAL OF STD & AIDS

Neisseria gonorrhoeae Treatment Failure and Susceptibility to Cefixime in Toronto, Canada

(2013) Vanessa G. Allen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Phenotypic and genetic characterization of the first two cases of extended-spectrum-cephalosporin-resistant Neisseria gonorrhoeae infection in South Africa and association with cefixime treatment failure

(2013) D. A. Lewis et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Failure of 500 mg of ceftriaxone to eradicate pharyngeal gonorrhoea, Australia

(2013) M. Y. Chen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

One confirmed and one suspected case of pharyngeal gonorrhoea treatment failure following 500mg ceftriaxone in Sydney, Australia

(2013) Phillip J. Read et al.   Sexual Health

Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea

(2012) Magnus Unemo et al.   Future Microbiology

Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain

(2012) J. Camara et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In VitroAntibacterial Activity of Modithromycin, a Novel 6,11-Bridged Bicyclolide, against Respiratory Pathogens, Including Macrolide-Resistant Gram-Positive Cocci

(2011) Takafumi Sato et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

(2011) Makoto Ohnishi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: NovelpenAMosaic Allele in a Successful International Clone Causes Treatment Failure

(2011) Magnus Unemo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro antibacterial activities of S-013420, a novel bicyclolide, against respiratory tract pathogens

(2010) T. Homma et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pharmacokinetics of EDP-420 after Ascending Single Oral Doses in Healthy Adult Volunteers

(2009) L.-J. Jiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of EDP-420 after Multiple Oral Doses in Healthy Adult Volunteers and in a Bioequivalence Study

(2009) L.-J. Jiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phenotypic and genetic characterization of the 2008 WHO Neisseria gonorrhoeae reference strain panel intended for global quality assurance and quality control of gonococcal antimicrobial resistance surveillance for public health purposes

(2009) M. Unemo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY