Lack of mitochondrial toxicity of darunavir, raltegravir and rilpivirine in neurons and hepatocytes: a comparison with efavirenz

Neuronal Bioenergetics and Acute Mitochondrial Dysfunction: A Clue to Understanding the Central Nervous System Side Effects of Efavirenz

(2014) Haryes A. Funes et al.   JOURNAL OF INFECTIOUS DISEASES

Rilpivirine Versus Efavirenz in HIV-1–Infected Subjects Receiving Emtricitabine/Tenofovir DF: Pooled 96-Week Data from ECHO and THRIVE Studies

(2013) M.R. Nelson et al.   HIV CLINICAL TRIALS

Neurological and psychiatric tolerability of rilpivirine (TMC278)vs.efavirenz in treatment-naïve, HIV-1-infected patients at 48 weeks

(2013) AM Mills et al.   HIV MEDICINE

Durable Efficacy and Safety of Raltegravir Versus Efavirenz When Combined With Tenofovir/Emtricitabine in Treatment-Naive HIV-1–Infected Patients

(2013) Jürgen K. Rockstroh et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

ER stress in human hepatic cells treated with Efavirenz: Mitochondria again

(2013) Nadezda Apostolova et al.   JOURNAL OF HEPATOLOGY

HIV-AIDS: much accomplished, much to do

(2013) Anthony S Fauci et al.   NATURE IMMUNOLOGY

Twenty Years of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Time to Reevaluate their Toxicity

(2012) A. Blas-Garcia et al.   CURRENT MEDICINAL CHEMISTRY

Antiretroviral neurotoxicity

(2012) Kevin Robertson et al.   JOURNAL OF NEUROVIROLOGY

96 Week Follow-Up of HIV-Infected Patients in Rescue with Raltegravir Plus Optimized Backbone Regimens: A Multicentre Italian Experience

(2012) Amedeo Capetti et al.   PLoS One

Liver Toxicity of Antiretroviral Drugs

(2012) Michelle Jones et al.   SEMINARS IN LIVER DISEASE

Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy

(2011) Nadezda Apostolova et al.   HEPATOLOGY

Efavirenz and 8-hydroxyefavirenz induce cell death via a JNK- and BimEL-dependent mechanism in primary human hepatocytes

(2011) Namandjé N. Bumpus   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition

(2011) Nadezda Apostolova et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Enhanced oxidative stress and increased mitochondrial mass during Efavirenz-induced apoptosis in human hepatic cells

(2010) N Apostolova et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells

(2010) Ana Blas-García et al.   HEPATOLOGY