Determining a clinical framework for use of cefepime and  -lactam/ -lactamase inhibitors in the treatment of infections caused by extended-spectrum- -lactamase-producing Enterobacteriaceae

Prevalence of β-Lactamase-Encoding Genes among Enterobacteriaceae Bacteremia Isolates Collected in 26 U.S. Hospitals: Report from the SENTRY Antimicrobial Surveillance Program (2010)

(2013) Mariana Castanheira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Background and Rationale for Revised Clinical and Laboratory Standards Institute Interpretive Criteria (Breakpoints) for Enterobacteriaceae andPseudomonas aeruginosa:I. Cephalosporins and Aztreonam

(2013) Michael N. Dudley et al.   CLINICAL INFECTIOUS DISEASES

Impact of Cefepime Therapy on Mortality among Patients with Bloodstream Infections Caused by Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae and Escherichia coli

(2012) Teena Chopra et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Outcomes With Extended or Continuous Versus Short-term Intravenous Infusion of Carbapenems and Piperacillin/Tazobactam: A Systematic Review and Meta-analysis

(2012) Matthew E. Falagas et al.   CLINICAL INFECTIOUS DISEASES

Editorial Commentary: Saving Lives With Optimal Antimicrobial Chemotherapy

(2012) G. L. Drusano et al.   CLINICAL INFECTIOUS DISEASES

Transmission Dynamics of Extended-Spectrum β-lactamase–Producing Enterobacteriaceae in the Tertiary Care Hospital and the Household Setting

(2012) Markus Hilty et al.   CLINICAL INFECTIOUS DISEASES

Cefepime Therapy for Monomicrobial Bacteremia Caused by Cefepime-Susceptible Extended-Spectrum Beta-Lactamase–Producing Enterobacteriaceae: MIC Matters

(2012) Nan-Yao Lee et al.   CLINICAL INFECTIOUS DISEASES

Carbapenems versus alternative antibiotics for the treatment of bacteraemia due to Enterobacteriaceae producing extended-spectrum  -lactamases: a systematic review and meta-analysis

(2012) K. Z. Vardakas et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Effects of confounders and intermediates on the association of bacteraemia caused by extended-spectrum β-lactamase-producing Enterobacteriaceae and patient outcome: a meta-analysis

(2012) Wouter C. Rottier et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Are susceptibility tests enough, or should laboratories still seek ESBLs and carbapenemases directly?

(2012) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Piperacillin–tazobactam as an initial empirical therapy of bacteremia caused by extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae

(2012) Cheol-In Kang et al.   JOURNAL OF INFECTION

 -Lactam/ -Lactam Inhibitor Combinations for the Treatment of Bacteremia Due to Extended-Spectrum  -Lactamase-Producing Escherichia coli: A Post Hoc Analysis of Prospective Cohorts

(2011) J. Rodriguez-Bano et al.   CLINICAL INFECTIOUS DISEASES

Can We Really Use ss-Lactam/ss-Lactam Inhibitor Combinations for the Treatment of Infections Caused by Extended-Spectrum ss-Lactamase-Producing Bacteria?

(2011) F. Perez et al.   CLINICAL INFECTIOUS DISEASES

The role of pharmacokinetics/pharmacodynamics in setting clinical MIC breakpoints: the EUCAST approach

(2011) J.W. Mouton et al.   CLINICAL MICROBIOLOGY AND INFECTION

Revisiting Beta-lactams – PK/PD improves dosing of old antibiotics

(2011) Alasdair MacGowan   CURRENT OPINION IN PHARMACOLOGY

Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective

(2011) Johan W. Mouton et al.   DRUG RESISTANCE UPDATES

Effects of clinical breakpoint changes in CLSI guidelines 2010/2011 and EUCAST guidelines 2011 on antibiotic susceptibility test reporting of Gram-negative bacilli

(2011) M. Hombach et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Susceptibility of Gram-Negative Pathogens Isolated from Patients with Complicated Intra-Abdominal Infections in the United States, 2007-2008: Results of the Study for Monitoring Antimicrobial Resistance Trends (SMART)

(2010) D. J. Hoban et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Antimicrobial susceptibility of intra-abdominal Gram-negative bacilli from Europe: SMART Europe 2008

(2010) S. Hawser et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Extended-Spectrum- -Lactamase, AmpC, and Carbapenemase Issues

(2010) K. S. Thomson   JOURNAL OF CLINICAL MICROBIOLOGY

Pharmacokinetics, Pharmacodynamics, and Monte Carlo Simulation

(2010) John S. Bradley et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Population Pharmacokinetics of High-Dose, Prolonged-Infusion Cefepime in Adult Critically Ill Patients with Ventilator-Associated Pneumonia

(2009) A. M. Nicasio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Community‐Onset Bacteremia Due to Extended‐Spectrum β‐Lactamase–ProducingEscherichia coli:Risk Factors and Prognosis

(2009) Jesús Rodríguez‐Baño et al.   CLINICAL INFECTIOUS DISEASES

Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion

(2009) Leonardo Lorente et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The changing epidemiology of resistance

(2009) P. M. Hawkey et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cephalosporin MIC Distribution of Extended-Spectrum- -Lactamase- and pAmpC-Producing Escherichia coli and Klebsiella Species

(2009) P. C. Kohner et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Extended-spectrum β-Lactamases: Implications for the Clinical Laboratory and Therapy

(2009) Sohei Harada et al.   Korean Journal of Laboratory Medicine

Community Infections Caused by Extended-Spectrum β-Lactamase–Producing Escherichia coli

(2008) Jesús Rodríguez-Baño et al.   ARCHIVES OF INTERNAL MEDICINE

Breakpoints for extended-spectrum β-lactamase-producing Enterobacteriacae: pharmacokinetic/pharmacodynamic considerations

(2008) A. MacGowan   CLINICAL MICROBIOLOGY AND INFECTION

Breakpoints for intravenously used cephalosporins in Enterobacteriaceae—EUCAST and CLSI breakpoints

(2008) G. Kahlmeter   CLINICAL MICROBIOLOGY AND INFECTION

Cefepime: a reappraisal in an era of increasing antimicrobial resistance

(2008) Andrea Endimiani et al.   Expert Review of Anti-Infective Therapy

Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic–pharmacodynamic models with Monte Carlo simulation

(2008) Christopher R. Frei et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Rapid Emergence of blaCTX-M Among Enterobacteriaceae in U.S. Medical Centers: Molecular Evaluation from the MYSTIC Program (2007)

(2008) Mariana Castanheira et al.   Microbial Drug Resistance