In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir

Transmission of influenza A(H1N1) 2009 pandemic viruses in Australian swine

(2012) Yi-Mo Deng et al.   Influenza and Other Respiratory Viruses

Cluster of Oseltamivir-Resistant 2009 Pandemic Influenza A (H1N1) Virus Infections on a Hospital Ward among Immunocompromised Patients—North Carolina, 2009

(2011) Luke F. Chen et al.   JOURNAL OF INFECTIOUS DISEASES

Real Time Enzyme Inhibition Assays Provide Insights into Differences in Binding of Neuraminidase Inhibitors to Wild Type and Mutant Influenza Viruses

(2011) Susan Barrett et al.   PLoS One

Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition

(2011) Christopher J. Vavricka et al.   PLoS Pathogens

Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice

(2010) Donald F. Smee et al.   ANTIVIRAL RESEARCH

Rapid Selection of Oseltamivir‐ and Peramivir‐Resistant Pandemic H1N1 Virus during Therapy in 2 Immunocompromised Hosts

(2010) Matthew J. Memoli et al.   CLINICAL INFECTIOUS DISEASES

Recovery of a Multidrug‐Resistant Strain of Pandemic Influenza A 2009 (H1N1) Virus Carrying a Dual H275Y/I223R Mutation from a Child after Prolonged Treatment with Oseltamivir

(2010) Ha T. Nguyen et al.   CLINICAL INFECTIOUS DISEASES

Oseltamivir-resistant 2009–2010 pandemic influenza A (H1N1) in an immunocompromised patient

(2010) P.A Chan et al.   CLINICAL MICROBIOLOGY AND INFECTION

In vitro selection of influenza B viruses with reduced sensitivity to neuraminidase inhibitors

(2010) S. Hatakeyama et al.   CLINICAL MICROBIOLOGY AND INFECTION

Pandemic H1N1 2009 influenza virus with the H275Y oseltamivir resistance neuraminidase mutation shows a small compromise in enzyme activity and viral fitness

(2010) D. W. Brookes et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

First case in Italy of acquired resistance to oseltamivir in an immunocompromised patient with influenza A/H1N1v infection

(2010) Giulia Campanini et al.   JOURNAL OF CLINICAL VIROLOGY

Generation and Characterization of Recombinant Pandemic Influenza A(H1N1) Viruses Resistant to Neuraminidase Inhibitors

(2010) Andrés Pizzorno et al.   JOURNAL OF INFECTIOUS DISEASES

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

(2010) Aaron J. Oakley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Altered Receptor Specificity and Cell Tropism of D222G Hemagglutinin Mutants Isolated from Fatal Cases of Pandemic A(H1N1) 2009 Influenza Virus

(2010) Y. Liu et al.   JOURNAL OF VIROLOGY

The Case for Integrated Delivery Systems

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Emergence of a Multidrug-Resistant Pandemic Influenza A (H1N1) Virus

(2010) Erhard van der Vries et al.   NEW ENGLAND JOURNAL OF MEDICINE

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

Efficacy of Oseltamivir-Zanamivir Combination Compared to Each Monotherapy for Seasonal Influenza: A Randomized Placebo-Controlled Trial

(2010) Xavier Duval et al.   PLOS MEDICINE

In Vitro Generation of Neuraminidase Inhibitor Resistance in A(H5N1) Influenza Viruses

(2009) A. C. Hurt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa

(2009) Aeron C. Hurt et al.   ANTIVIRAL RESEARCH

Detection of antiviral resistance and genetic lineage markers in influenza B virus neuraminidase using pyrosequencing

(2009) Tiffany G. Sheu et al.   ANTIVIRAL RESEARCH

Generation of Live Attenuated Novel Influenza Virus A/California/7/09 (H1N1) Vaccines with High Yield in Embryonated Chicken Eggs

(2009) Z. Chen et al.   JOURNAL OF VIROLOGY

A Novel Neuraminidase Deletion Mutation Conferring Resistance to Oseltamivir in Clinical Influenza A/H3N2 Virus

(2008) Yacine Abed et al.   JOURNAL OF INFECTIOUS DISEASES

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

(2008) Patrick J. Collins et al.   NATURE

Enzymatic Properties of the Neuraminidase of Seasonal H1N1 Influenza Viruses Provide Insights for the Emergence of Natural Resistance to Oseltamivir

(2008) Marie-Anne Rameix-Welti et al.   PLoS Pathogens