Antiviral applications of Toll-like receptor agonists

The Innate Immune Response, Clinical Outcomes, and Ex Vivo HCV Antiviral Efficacy of a TLR7 Agonist (PF-4878691)

(2011) M D Fidock et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV™ safety and efficacy

(2011) Curtis Cooper et al.   Expert Review of Vaccines

Randomized Phase III Trial of Paclitaxel/Carboplatin With or Without PF-3512676 (Toll-Like Receptor 9 Agonist) As First-Line Treatment for Advanced Non–Small-Cell Lung Cancer

(2011) Vera Hirsh et al.   JOURNAL OF CLINICAL ONCOLOGY

The Structural Biology of Toll-like Receptors

(2011) Istvan Botos et al.   STRUCTURE

Telaprevir: a new hope in the treatment of chronic hepatitis C?

(2010) Andrew J. Fowell et al.   ADVANCES IN THERAPY

Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States

(2010) S. A. Grossman et al.   CLINICAL CANCER RESEARCH

Localisation and trafficking of Toll-like receptors: an important mode of regulation

(2010) Anne F McGettrick et al.   CURRENT OPINION IN IMMUNOLOGY

Synthesis and Biological Evaluation of 8-Oxoadenine Derivatives as Toll-like Receptor 7 Agonists Introducing the Antedrug Concept

(2010) Ayumu Kurimoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of Nature and Length of Linker Incorporated in Agonists on Toll-Like Receptor 9-Mediated Immune Responses

(2010) Mallikarjuna Reddy Putta et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure−Activity Relationships in Human Toll-Like Receptor 7-Active Imidazoquinoline Analogues

(2010) Nikunj M. Shukla et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting Toll-like receptors: emerging therapeutics?

(2010) Elizabeth J. Hennessy et al.   NATURE REVIEWS DRUG DISCOVERY

A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma

(2010) M. R. Rosenfeld et al.   NEURO-ONCOLOGY

The discovery of a novel prototype small molecule TLR7 agonist for the treatment of hepatitis C virus infection

(2010) David C. Pryde et al.   MedChemComm

Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma

(2009) Jonathan W. Friedberg et al.   BRITISH JOURNAL OF HAEMATOLOGY

Antiviral Role of Toll-Like Receptor-3 Agonists Against Seasonal and Avian Influenza Viruses

(2009) J. Wong et al.   CURRENT PHARMACEUTICAL DESIGN

Activation of Interferon Response Through Toll-Like Receptor 3 Impacts Viral Pathogenesis and Pulmonary Toll-Like Receptor Expression During Respiratory Syncytial Virus and Influenza Infections in the Cotton Rat Sigmodon hispidus Model

(2009) Marina S. Boukhvalova et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Toll-like Receptor 7 Selective Synthetic Oligoribonucleotide Agonists: Synthesis and Structure−Activity Relationship Studies

(2009) Tao Lan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small Molecule Modulators of Toll-like Receptors

(2008) Michael Czarniecki   JOURNAL OF MEDICINAL CHEMISTRY