Impact of drug transporters on cellular resistance towards saquinavir and darunavir

Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines

(2010) W. F. W. Bierman et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

P-Glycoprotein Mediates Efflux Transport of Darunavir in Human Intestinal Caco-2 and ABCB1 Gene-Transfected Renal LLC-PK1 Cell Lines

(2009) Hiromi Fujimoto et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Intracellular ‘boosting’ of darunavir using known transport inhibitors in primary PBMC

(2009) Wai San Kwan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Darunavir

(2009) Kate McKeage et al.   DRUGS

Induction of Multiple Drug Transporters by Efavirenz

(2009) Johanna Weiss et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The complexities of antiretroviral drug–drug interactions: role of ABC and SLC transporters

(2009) Olena Kis et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Sertraline and Its Metabolite Desmethylsertraline, but not Bupropion or Its Three Major Metabolites, Have High Affinity for P-Glycoprotein

(2008) Jun-Sheng Wang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Intestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease Inhibitors

(2008) A. Gupta et al.   DRUG METABOLISM AND DISPOSITION

Comparison of the induction of P-glycoprotein activity by nucleotide, nucleoside, and non-nucleoside reverse transcriptase inhibitors

(2007) Johanna Weiss et al.   EUROPEAN JOURNAL OF PHARMACOLOGY