Differential impact of the HIV-1 non-nucleoside reverse transcriptase inhibitor mutations K103N and M230L on viral replication and enzyme function

Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled Phase III clinical studies

(2010) Johan Vingerhoets et al.   AIDS

Combinations of Mutations in the Connection Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Assessing the Impact on Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitor Resistance

(2010) S. Gupta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The M230L Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutation in HIV-1 Reverse Transcriptase Impairs Enzymatic Function and Viral Replicative Capacity

(2010) H. T. Xu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor

(2010) H. Javanbakht et al.   ANTIVIRAL RESEARCH

Constrained patterns of covariation and clustering of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations

(2010) Elizabeth C. Reuman et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design

(2010) Eric B. Lansdon et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Novel Molecular Mechanism of Dual Resistance to Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors

(2010) G. N. Nikolenko et al.   JOURNAL OF VIROLOGY

Nonnucleoside Reverse Transcriptase Inhibitor Resistance and the Role of the Second-Generation Agents

(2009) Jessica Adams et al.   ANNALS OF PHARMACOTHERAPY

Factors Associated with Virological Response to Etravirine in Nonnucleoside Reverse Transcriptase Inhibitor-Experienced HIV-1-Infected Patients

(2009) A.-G. Marcelin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Solution characterization of [methyl-13C]methionine HIV-1 reverse transcriptase by NMR spectroscopy

(2009) Xunhai Zheng et al.   ANTIVIRAL RESEARCH

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989–2009)

(2009) Marie-Pierre de Béthune   ANTIVIRAL RESEARCH

Etravirine, a Next‐Generation Nonnucleoside Reverse‐Transcriptase Inhbitor

(2009) Leonard B. Johnson et al.   CLINICAL INFECTIOUS DISEASES

Phenotypic impact of resistance mutations on etravirine susceptibility in HIV patients with prior failure to nonnucleoside analogues

(2008) Eva Poveda et al.   AIDS

Impact of Residues in the Nonnucleoside Reverse Transcriptase Inhibitor Binding Pocket on HIV-1 Reverse Transcriptase Heterodimer Stability

(2008) Anna Figueiredo et al.   CURRENT HIV RESEARCH

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

(2008) Nicolas Sluis-Cremer et al.   VIRUS RESEARCH

Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase

(2008) Jingshan Ren et al.   VIRUS RESEARCH