Article
Veterinary Sciences
Donald Sockett, Ryan M. Breuer, Lindsey W. Smith, Nicholas S. Keuler, Thomas Earleywine
Summary: This study investigates the use of a digital Brix refractometer to predict colostrum IgG concentration. The results show that the refractometer is not suitable for predicting IgG concentration, but different %Brix cutoffs can be used for estimating minimum colostral IgG concentrations.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Review
Developmental Biology
Lawrence P. Reynolds, Wellison J. S. Diniz, Matthew S. Crouse, Joel S. Caton, Carl R. Dahlen, Pawel P. Borowicz, Alison K. Ward
Summary: Developmental programming refers to the long-term changes in gene expression caused by stressors during development, which can affect organ structure and function. Maternal nutrition plays a crucial role in the developmental program. Future research should focus on the effects of developmental programming on the offspring's life course and subsequent generations, as well as utilizing the positive aspects of developmental programming.
REPRODUCTION FERTILITY AND DEVELOPMENT
(2023)
Article
Agriculture, Dairy & Animal Science
Do T. Hue, Rebel Skirving, Tong Chen, John L. Williams, Cynthia D. K. Bottema, Kiro Petrovski
Summary: This study compared the absorption of nutrients from colostrum in different sources in newborn dairy bull calves, finding that calves receiving identical colostrum from the same cow had similar IgG levels, and even the pooled colostrum provided sufficient transfer of IgG when fed within 4 hours after birth.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Veterinary Sciences
Han Wang, Samy A. Elsaadawy, Zhaohai Wu, Dengpan P. Bu
Summary: This study shows that providing ruminally-protected amino acids to transition dairy cows can have positive effects on the immunity and performance of their offspring, including colostrum quality, serum total protein concentrations, plasma immunoglobulin G concentrations, and average daily gain. Maternal supplementation with RPM or RPL, or the combination of both, could be a beneficial strategy for improving calf performance.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Review
Nutrition & Dietetics
Long T. Nguyen, Carol A. Pollock, Sonia Saad
Summary: The developmental programming hypothesis suggests that adverse environmental insults during critical developmental periods increase the risk of diseases in later life. Kidneys are susceptible to such insults, particularly due to peri-gestational nutrition, which affects kidney development and metabolism. Recent studies have identified oxidative stress, mitochondrial dysfunction, epigenetic modifications, and metabolic changes as potential novel pathways for therapeutic intervention.
Article
Genetics & Heredity
Wellison J. S. Diniz, Gerd Bobe, Joseph J. Klopfenstein, Yunus Gultekin, T. Zane Davis, Alison K. Ward, Jean A. Hall
Summary: The study investigated the effects of maternal organic selenium supplementation during different pregnancy trimesters on genome-wide transcriptome profiles of beef calf. The results showed that organic selenium supplementation can impact immune function and muscle development in newborn calves depending on the trimester of supplementation.
Review
Agriculture, Dairy & Animal Science
A. J. Lopez, A. J. Heinrichs
Summary: Feeding maternal colostrum to newborn calves in their first hours of life is crucial for their development. Colostrum contains various nutrients and immunoglobulins, which play a significant role in building the calves' immune system. The successful transfer of passive immunity is determined by the calf's consumption of an adequate amount of immunoglobulins. Factors such as colostrum IgG concentration, quantity fed, and age of the calf at colostrum feeding influence the outcome of passive immunity. Monitoring serum IgG concentrations is recommended to assess the overall management of colostrum. Apparent efficiency of immunoglobulin absorption can be determined through direct or indirect methods and used to evaluate the prevalence of successful or failed passive immunity transfer.
JOURNAL OF DAIRY SCIENCE
(2022)
Review
Agriculture, Dairy & Animal Science
Sarah McCoski, Amanda Bradbery, Rodrigo da Silva Marques, Christian Posbergh, Carla Sanford
Summary: Current research on the interaction between maternal nutrition and developmental programming in male offspring primarily focuses on the effects of maternal diet on female offspring, with less attention on male offspring. Poor maternal nutrition can lead to various maladaptive phenotypes in offspring, but the specific outcomes in male offspring remain poorly understood.
Article
Biochemistry & Molecular Biology
Josip Novoselec, Zeljka Klir Salavardic, Mislav Didara, Maja Novoselec, Rosemary Vukovic, Suzana Cavar, Zvonko Antunovic
Summary: This study investigated the effects of dietary selenium supplementation in late-gestation ewes on blood selenium concentrations and indicators of metabolic and antioxidant status in both ewes and their lambs. It was found that selenium supplementation significantly increased selenium concentration and antioxidant enzyme activity, while decreasing malondialdehyde concentration in both ewes and their lambs. The transfer of selenium from ewes to lambs during the suckling period was found to be more efficient when the diet was supplemented with organic selenium compared to inorganic selenium.
Article
Virology
Seyit Ahmet Erol, Naci Polat, Sevginur Akdas, Pelin Aribal Ayral, Ali Taner Anuk, Eda Ozden Tokalioglu, Sule Goncu Ayhan, Burcu Kesikli, Merve Nur Ceylan, Atakan Tanacan, Ozlem Moraloglu Tekin, Nuray Yazihan, Dilek Sahin
Summary: This study investigated the selenium status of pregnant women with COVID-19 and found that their serum selenium levels were significantly lower in the second and third trimesters compared to healthy pregnant women. Maternal selenium level was negatively correlated with gestational week, D-dimer, and IL-6 level, while positively correlated with white blood cell, neutrophil, lymphocyte count, and other parameters. Serum selenium level gradually decreased during pregnancy, with a more pronounced decrease in the presence of COVID-19 infection.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Biochemistry & Molecular Biology
Charlotte Lauridsen, Anna Amanda Schonherz, Soren Hojsgaard
Summary: The study found that the high antioxidant treatment increased selenium and alpha-tocopherol concentrations in piglets' plasma compared to the low treatment. It also showed that the high treatment affected the immunoglobulins in milk and sow plasma, and influenced the activity of glutathione peroxidase, levels of inflammatory markers, and cytokines in piglets. Overall, the study suggests that improving antioxidant status through maternal dietary provision enhances the robustness of offspring through immunomodulatory mechanisms.
Article
Virology
Laura Marchi, Annalisa Vidiri, Emanuele Arturo Fera, Marta Pallottini, Federica Perelli, Monica Gardelli, Tamara Brunelli, Paolo Dal Poggetto, Elena Martelli, Gianluca Straface, Fabrizio Signore, Ismaele Fusco, Pier Luigi Vasarri, Giovanni Scambia, Anna Franca Cavaliere
Summary: This study describes the transplacental passage of specific SARS-CoV-2 IgG antibodies from mothers to their newborns during pregnancy. Analysis of 143 mother-infant dyads showed that 86% of pregnant women with a positive SARS-CoV-2 PCR >14 days before delivery developed specific IgG, and 84% of their infants showed transplacental passage of IgG.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Review
Immunology
Qihui Li, Siwang Yang, Xiaoli Zhang, Xinghong Liu, Zhihui Wu, Yingao Qi, Wutai Guan, Man Ren, Shihai Zhang
Summary: Immature immune system and environmental stress increase infection risk in nursing pigs. Nutritional and physiological conditions of sows affect the growth, development, and disease resistance of the offspring. Studies have shown that providing sows with certain nutrients can regulate piglets' immunity and inflammatory response.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Laura G. Sherlock, Durganili Balasubramaniyan, Lijun Zheng, Miguel Zarate, Thomas Sizemore, Cassidy Delaney, Trent E. Tipple, Clyde J. Wright, Eva Nozik-Grayck
Summary: Maternal selenium deficiency leads to decreased neonatal selenium levels and increased risk for neonatal morbidities. The impact of maternal selenium deficiency varies across different organs and selenoproteins. Research suggests that neonates experience earlier depletion of selenoenzyme activity in the liver and circulation after maternal selenium deficiency, indicating a potential escalation of risk to the neonate with prolonged maternal selenium deficiency.
Article
Immunology
Daniel C. Payne, Monica McNeal, Mary Allen Staat, Alexandra M. Piasecki, Allison Cline, Emily DeFranco, Michelle G. Goveia, Umesh D. Parashar, Rachel M. Burke, Ardythe L. Morrow
Summary: Rotavirus-specific antibodies continue to be transferred from US mothers to their offspring in the post-rotavirus vaccine era, despite significant decreases in childhood rotavirus gastroenteritis.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Agriculture, Dairy & Animal Science
Kacie L. McCarthy, Ana Clara B. Menezes, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, Alison K. Ward, Pawel P. Borowicz, Lawrence P. Reynolds, Kevin K. Sedivec, J. Chris Forcherio, Ronald Scott, Joel S. Caton, Carl R. Dahlen
Summary: Maternal vitamin and mineral supplementation during pre-breeding and the first trimester of gestation resulted in higher concentrations of selenium, copper, and cobalt in beef heifers and their fetuses. These trace minerals are essential components of the antioxidant system and may have positive impacts on the immune system of the future offspring. Additionally, low rates of gain during gestation resulted in higher concentrations of molybdenum and cobalt in fetal liver.
Article
Biochemistry & Molecular Biology
Matthew S. Crouse, Kacie L. McCarthy, Ana Clara B. Menezes, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri Dorsam, Tammi L. Neville, Alison K. Ward, Pawel P. Borowicz, Lawrence P. Reynolds, Kevin K. Sedivec, J. Chris Forcherio, Ronald Scott, Joel S. Caton, Carl R. Dahlen
Summary: The objective of this study was to evaluate the effects of feeding heifers a vitamin and mineral supplement and targeting divergent rates of weight gain during early gestation on the fetal liver amino acid, carbohydrate, and energy profile at d 83 of gestation. The results showed that both rate of weight gain and vitamin/mineral supplementation significantly affected the metabolites in the fetal liver. In addition, the study found that vitamin and mineral supplementation had different effects on the TCA cycle and Oxidative Phosphorylation pathways within the Energy Metabolism superpathway.
Review
Nutrition & Dietetics
Carl R. Dahlen, Lawrence P. Reynolds, Joel S. Caton
Summary: Selenium is an essential micronutrient in both vertebrates and invertebrates, and its deficiency or excess can lead to reproductive insufficiency and dysfunction in both males and females. It is associated with various complications during pregnancy and affects gamete and embryo development. Selenium has positive effects on fertility, embryonic development, and antioxidant properties. Supplementation of selenium can improve fetal growth and development, as well as influence placental and mammary gland growth. Further research is needed to explore the potential benefits of selenium supplementation in reproductive processes across different species.
FRONTIERS IN NUTRITION
(2022)
Article
Agriculture, Dairy & Animal Science
Matthew S. Crouse, Harvey C. Freetly, Amanda K. Lindholm-Perry, Bryan W. Neville, William T. Oliver, Robert T. Lee, Jessica G. Syring, Layla E. King, Lawrence P. Reynolds, Carl R. Dahlen, Joel S. Caton, Alison K. Ward, Robert A. Cushman
Summary: The study aimed to determine the optimal doses of vitamins B-12 and folate for beef heifers to maintain increased levels of these nutrients in circulation. Results showed that weekly injections of 20 mg of B-12 and 320 mg of folate were effective in sustaining elevated concentrations of these nutrients in serum.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Natalie B. Duncan, Katy S. Stoecklein, Andrew P. Foote, Allison M. Meyer
Summary: This study compared the effects of dam parity on perinatal nutrient availability in beef cattle. The results showed that calves born to first-parity dams were smaller at birth, had smaller placentas, but required more energy and exhibited more stress as neonates. These findings provide opportunities for improved management of first-parity dams.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
A. R. Tanner, M. L. Bauer, K. C. Swanson, V. C. Kennedy, J. D. Kirsch, J. Gaspers, N. Negrin-Pereira, A. B. P. Fontoura, G. A. Perry, G. Stokka, A. Rodas-Gonzalez, A. Ward, C. R. Dahlen, B. Neville, P. P. Borowicz, L. P. Reynolds, K. H. Ominski, K. A. Vonnahme
Summary: The purpose of this study was to evaluate the effects of supplementing corn to gestating beef cows fed low-quality forage on uterine and mammary hemodynamics and neonatal performance. The results showed that corn supplementation enhanced uterine and mammary hemodynamics and increased placental microvascularity. Corn can be a good substitute for hay when cost and availability are economically advantageous to the producer.
Review
Developmental Biology
Lawrence P. Reynolds, Wellison J. S. Diniz, Matthew S. Crouse, Joel S. Caton, Carl R. Dahlen, Pawel P. Borowicz, Alison K. Ward
Summary: Developmental programming refers to the long-term changes in gene expression caused by stressors during development, which can affect organ structure and function. Maternal nutrition plays a crucial role in the developmental program. Future research should focus on the effects of developmental programming on the offspring's life course and subsequent generations, as well as utilizing the positive aspects of developmental programming.
REPRODUCTION FERTILITY AND DEVELOPMENT
(2023)
Article
Biochemistry & Molecular Biology
Ana Clara B. Menezes, Carl R. Dahlen, Kacie L. McCarthy, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, Alison K. Ward, Pawel P. Borowicz, Lawrence P. Reynolds, Kevin K. Sedivec, J. Chris Forcherio, Ronald Scott, Joel S. Caton, Matthew S. Crouse
Summary: In this study, the hepatic lipid metabolic profiles of bovine fetuses were evaluated in response to maternal vitamin and mineral supplementation and different rates of gain. The results showed that maternal body weight gain had a greater influence on fetal lipid profiles than vitamin and mineral supplementation, with lower rates of gain resulting in increased lipid composition.
Article
Agriculture, Dairy & Animal Science
Colby A. Redifer, Lindsey G. Wichman, Abigail R. Rathert-Williams, Harvey C. Freetly, Allison M. Meyer
Summary: Beef heifers experiencing late gestational nutrient restriction prioritize fetal growth and colostrum production over maternal growth. The restricted nutrient intake during late gestation results in the catabolism of maternal tissue stores to meet the demands of the fetus and colostrum production.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Wellison J. S. Diniz, Alison K. Ward, Kacie L. McCarthy, Cierrah J. Kassetas, Friederike Baumgaertner, Lawrence P. Reynolds, Pawel P. Borowicz, Kevin K. Sedivec, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, J. Chris Forcherio, Ronald Scott, Joel S. Caton, Carl R. Dahlen
Summary: Maternal nutrient supply during the periconceptual period has long-term effects on fetal development and tissue function. Our study investigated the impacts of maternal vitamin and mineral supplementation and rate of body-weight gain during early pregnancy on fetal liver development and gene expression profiles. We found that maternal nutrition during the periconceptual period affects fetal hepatic function through altered expression of energy- and lipid-related genes.
Review
Biochemistry & Molecular Biology
Muhammad Anas, Wellison J. S. Diniz, Ana Clara B. Menezes, Lawrence P. Reynolds, Joel S. Caton, Carl R. Dahlen, Alison K. Ward
Summary: Maternal mineral nutrition during critical phases of fetal development can have lifelong impacts on individual productivity. Research has focused on the role of macronutrients in genome function and fetal programming, but little is known about the role of micronutrients and minerals in livestock species. This review will address the effects of maternal dietary mineral supply on fetal development in cattle and draw parallels with research in other animals and cell lines.
Article
Agriculture, Dairy & Animal Science
Lindsey G. Wichman, Colby A. Redifer, Allison M. Meyer
Summary: Nutrient restriction during late gestation negatively affects the growth and immune function of calves, resulting in weaker vigor and more trauma after birth.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Abigail R. Rathert-Williams, Ann L. Kenny, Bongkosh Vardhanabhuti, Thomas B. McFadden, Allison M. Meyer
Summary: The objective of this study was to develop colorimetric methods to accurately measure the nutrient concentrations of beef cow colostrum and milk and evaluate if the yield of colostrum from a single rear quarter is representative of the complete collection. The developed colorimetric methods were compared to Fourier transform infrared spectroscopy (FTIR) analysis to determine the accuracy of FTIR for beef cow colostrum and milk. The results showed that the colorimetric methods had good accuracy for lactose, triglyceride, protein, and urea nitrogen measurements, and were more accurate than FTIR analysis.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Colby A. Redifer, Daniel D. Loy, Curtis R. Youngs, Chong Wang, Allison M. Meyer, Heather A. Tucker, Patrick J. Gunn
Summary: The objective of this study was to evaluate the effects of peripartum supplementation of a methionine hydroxy analogue (MHA) on dam and progeny performance in primiparous, spring-calving beef females. Results showed that supplementation of MHA from 45 to 81 days pre-calving increased milk fat concentration post-calving, but did not improve progeny growth or dam reproductive performance.
TRANSLATIONAL ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Emma L. Stephenson, Abigail R. Rathert-Williams, Ann L. Kenny, Dusty W. Nagy, Brian M. Shoemake, Thomas B. Mcfadden, Heather A. Tucker, Allison M. Meyer
Summary: The effects of Cu, Zn, and Mn source and inclusion during late gestation on maternal and neonatal calf mineral status were evaluated in this study. The results showed that the source and inclusion of Cu, Zn, and Mn altered the mineral status of cows and calves, but had no significant effects on calf size, vigor, passive transfer, and pre-weaning growth.
TRANSLATIONAL ANIMAL SCIENCE
(2023)