Journal
JOURNAL OF ANIMAL BREEDING AND GENETICS
Volume 131, Issue 4, Pages 249-257Publisher
WILEY
DOI: 10.1111/jbg.12089
Keywords
Genomic selection; multibreed; marker-based relationship matrix; linkage disequilibrium phase consistence
Categories
Funding
- Green Development and Demonstration Programme by the Danish Directorate for Food, Fisheries and Agri Business (Copenhagen, Denmark) [3405-10-0137]
- Milk Levy Fund (Aarhus, Denmark) [3405-10-0137]
- VikingGenetics (Randers, Denmark) [3405-10-0137]
- Nordic Cattle Genetic Evaluation (Aarhus, Denmark) [3405-10-0137]
- Aarhus University (Aarhus, Denmark) [3405-10-0137]
- Chinese Scholarship Council
Ask authors/readers for more resources
This study investigated genomic predictions across Nordic Holstein and Nordic Red using various genomic relationship matrices. Different sources of information, such as consistencies of linkage disequilibrium (LD) phase and marker effects, were used to construct the genomic relationship matrices (G-matrices) across these two breeds. Single-trait genomic best linear unbiased prediction (GBLUP) model and two-trait GBLUP model were used for single-breed and two-breed genomic predictions. The data included 5215 Nordic Holstein bulls and 4361 Nordic Red bulls, which was composed of three populations: Danish Red, Swedish Red and Finnish Ayrshire. The bulls were genotyped with 50 000 SNP chip. Using the two-breed predictions with a joint Nordic Holstein and Nordic Red reference population, accuracies increased slightly for all traits in Nordic Red, but only for some traits in Nordic Holstein. Among the three subpopulations of Nordic Red, accuracies increased more for Danish Red than for Swedish Red and Finnish Ayrshire. This is because closer genetic relationships exist between Danish Red and Nordic Holstein. Among Danish Red, individuals with higher genomic relationship coefficients with Nordic Holstein showed more increased accuracies in the two-breed predictions. Weighting the two-breed G-matrices by LD phase consistencies, marker effects or both did not further improve accuracies of the two-breed predictions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available