Article
Agriculture, Dairy & Animal Science
Xiufen Zhang, Qilin Wu, Wenxuan Zheng, Chuang Liu, Liang Huang, Xin Zuo, Wenquan Xiao, Xiaofeng Han, Hui Ye, Wence Wang, Lin Yang, Yongwen Zhu
Summary: This study investigated the effects of exogenous fatty acid intervention on embryonic development in an avian embryo model. It was found that hepatic lipid and fatty acid metabolism play critical roles in embryogenesis. The intervention with oleic acid affected lipid metabolism and gene expression related to fatty acid uptake, synthesis, and oxidation in the embryos.
Article
Chemistry, Physical
Fazhan Wang, Meng Zhang, Meiling Tian, Jia Lou, Longze Pan, Xiaoke Gao, Lijing Zhang, Xiaohan Lou, Linyu Zhu, Yuqiao Sheng, Ming Wang, Rui Xue, Wenjing Deng, Shuai Shao, Zhihai Qin
Summary: Based on the metabolic behavior of long-chain saturated fatty acids, we developed fatty acid-doped lipid nanoparticles capable of mediating differential protein expressions in the liver and spleen. Using these spleen-selective nanoparticles for immunization in a mouse model showed enhanced antigen-specific T cell immune responses and potent immunotherapeutic and immunoprophylactic effects.
Article
Environmental Sciences
Murugesan Sobanaa, Ragothaman Prathiviraj, Joseph Selvin, Munisamy Prathaban
Summary: The unprecedented growth in population and anthropogenic activities have posed challenges to the future climate patterns, particularly the emissions of methane. However, various mitigation strategies can significantly reduce the global methane burden and have positive impacts on climate change, economy, human health, and agriculture.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Muyu Yu, Miriayi Alimujiang, Lili Hu, Fang Liu, Yuqian Bao, Jun Yin
Summary: The study indicated that BBR inhibits complex I in the gut and liver, leading to the suppression of lipid metabolism and improvement in obesity and fatty liver, independently of intestinal bacteria.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Oncology
Lisa Lemberger, Renate Wagner, Gerwin Heller, Dietmar Pils, Thomas W. Grunt
Summary: Ovarian cancer is a deadly gynecological cancer with late diagnosis often leading to peritoneal metastasis. The growth of ovarian cancer cells depends on lipid nutrients, either synthesized within the cells or imported from the surrounding tissues. Inhibiting lipid uptake and transport proteins reduces cell growth, induces cell cycle arrest and apoptosis, indicating the high sensitivity of ovarian cancer cells to lipid deficiency. These findings provide a theoretical basis for the development of novel lipid-antimetabolic strategies against ovarian cancer.
Article
Chemistry, Applied
Laura Boetje, Xiaohong Lan, Fitrilia Silvianti, Jur van Dijken, Michael Polhuis, Katja Loos
Summary: This study presents a series of starch esters synthesized through transesterification reactions catalyzed by TBD in DMSO. By purging the reaction flask with nitrogen, the degree of substitution was increased. Long-chain fatty acids exhibited the most significant increase in DS, while starch esters from unsaturated fatty acids showed lower Tg and higher hydrophobicity compared to pristine starch.
CARBOHYDRATE POLYMERS
(2022)
Review
Plant Sciences
Yingqi Cai, Xiao-Hong Yu, John Shanklin
Summary: Plants convert carbohydrates into energy-dense lipids through photosynthesis, making plant oils an economically and sustainably attractive feedstock for biofuels and value-added bioproducts. Various strategies have been developed to enhance lipid accumulation and produce specialty lipids with increased uses and value. Successful metabolic engineering involves expression of lipogenic factors from other sources or with specialized functionality.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Environmental Sciences
Chen Xu, Susu Shen, Beibei Zhou, Yuanyuan Feng, Zhu He, Linlin Shi, Yu Wang, Haihou Wang, Tripti Mishra, Lihong Xue
Summary: Long-term non-P application in rice paddy fields significantly increases methane emissions and affects the abundance and diversity of methane-producing microorganisms. A study conducted in the Tai Lake region showed that appropriate phosphorus application can reduce methane emissions while ensuring crop yield.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Agronomy
Le Qi, Prem Pokharel, Rong Huang, Scott X. Chang, Xiaoqiang Gong, Tao Sun, Yueqiang Wu, Zifang Wang, Ming Gao
Summary: Retaining crop residues and reducing chemical fertilizer application can maintain crop yield and agronomic efficiency in a vegetable-rice rotation, but may increase methane emissions during the rice cultivation season.
AGRICULTURAL AND FOREST METEOROLOGY
(2023)
Article
Agricultural Engineering
Kun Wu, Weijia Xu, Chun Wang, Jian Lu, Xia He
Summary: The study demonstrates that the formation of calcium palmitate can significantly enhance the efficiency of methane production from LCFAs, primarily due to enhanced bio-aggregation and significant changes in microbial community. Conversely, the formation of calcium oleate decreases the efficiency of methane production from LCFAs, resulting in a small difference in methane recovery.
BIORESOURCE TECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Guangyuan Zhao, Yuying Tan, Horacio Cardenas, David Vayngart, Yinu Wang, Hao Huang, Russell Keathley, Jian-Jun Wei, Christina R. Ferreira, Sandra Orsulic, Ji-Xin Cheng, Daniela Matei
Summary: Fatty acids are an important energy source and component of cell membranes. This study investigates the impact of the balance between saturated fatty acids (SFAs) and unsaturated fatty acids (UFAs), regulated by stearoyl Co-A desaturase (SCD), on ovarian cancer cell survival and tumor progression. Depletion or inhibition of SCD leads to lower levels of UFAs, triggering endoplasmic reticulum (ER) stress response and cell death. However, supplementation with UFAs and reequilibration of SFA/UFA levels rescues stress and apoptosis. This research highlights the importance of targeting lipid balance in the treatment of ovarian cancer.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Agriculture, Dairy & Animal Science
D. W. Pitta, A. Melgar, A. N. Hristov, N. Indugu, K. S. Narayan, C. Pappalardo, M. L. Hennessy, B. Vecchiarelli, V Kaplan-Shabtai, M. Kindermann, N. Walker
Summary: The study investigated the effect of 3-nitrooxypropanol (3-NOP) on different methanogenic lineages in the rumen of dairy cows, revealing variations in metabolic activities and sensitivities to 3-NOP among methanogens. The abundance of individual methanogens was driven by dietary composition, dry matter intake, and hydrogen concentrations in the rumen.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Plant Sciences
Renato Crespo Pereira, Wladimir Costa Paradas, Rodrigo Tomazetto de Carvalho, Davyson de Lima Moreira, Alphonse Kelecom, Raoni Moreira Ferreira Passos, Georgia Correa Atella, Leonardo Tavares Salgado
Summary: The brown marine macroalga Padina gymnospora produces defensive chemicals and calcium carbonate on its surface as potential protections against herbivory. The chemical compounds extracted from P. gymnospora showed a significant reduction in consumption by the sea urchin Lytechinus variegatus, while the calcium carbonate did not provide physical protection. A specific hydrocarbon compound, 5Z,8Z,11Z,14Z-heneicosatetraene, exhibited a significant defensive property against the sea urchin.
Article
Chemistry, Medicinal
Wen Yanran, Soohan Jung, Kwang Suk Ko
Summary: Obesity-associated nonalcoholic fatty liver disease (NAFLD) is characterized by excessive intrahepatic lipid accumulation. This study found that Prohibitin 1 (PHB1) plays an important role in hepatocyte proliferation and lipid metabolism. Inhibition of PHB1 led to decreased cell viability, increased expression of lipid metabolism enzymes, activation of endoplasmic reticulum (ER) stress response, and altered triglyceride synthesis. These cytotoxic effects were further exacerbated by excessive palmitic acid treatment.
JOURNAL OF MEDICINAL FOOD
(2022)
Article
Environmental Sciences
Mengdie Jiang, Peng Xu, Lei Wu, Jinsong Zhao, Hongtao Wu, Shan Lin, Tewu Yang, Junming Tu, Ronggui Hu
Summary: Appropriate crop rotation in rice field is important for maintaining soil fertility and rice productivity. This study found that changing rice rotation patterns can reduce methane emissions by regulating soil properties and altering methanogenic and methanotrophic communities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Zoology
Annelies De Cuyper, Daniela E. Winkler, Thomas Tuetken, Guido Bosch, Juergen Hummel, Michael Kreuzer, Arturo Munoz Saravia, Geert P. J. Janssens, Marcus Clauss
Summary: The study demonstrates that although guinea pigs increase their dry matter intake on bamboo diet, the lignin and silica in bamboo have negative effects on digestion, resulting in low digestibility and slower body weight gain.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
M. Heuel, C. Sandrock, F. Leiber, A. Mathys, M. Gold, C. Zurbrueegg, I. D. M. Gangnat, M. Kreuzer, M. Terranova
Summary: Due to the increasing global demand for sustainable animal protein, there is a search for alternatives to soybeans in animal feed. This study compared the nutritional value of black soldier fly larvae (BSFL) with soybeans in feeding organic broilers. The results suggest that BSFL may be superior to soybeans, but the high lauric acid content in BSFL-fed broilers could negatively impact meat quality.
BRITISH POULTRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
I. M. D. Gangnat, M. Kreuzer
Summary: This study investigated the effect of Solanum glaucophyllum in the diet of sows on farrowing duration and progeny survival and growth. The results showed that Solanum glaucophyllum had no positive effect on these factors.
JOURNAL OF ANIMAL AND FEED SCIENCES
(2022)
Article
Biodiversity Conservation
Caren M. Pauler, Tobias Zehnder, Markus Staudinger, Andreas Luescher, Michael Kreuzer, Joeel Berard, Manuel K. Schneider
Summary: This study finds that green alder shrubs overgrow European mountain pastures, and while cattle cannot prevent their expansion, sheep are better suited for clearing green alder than goats. In terms of forest regeneration, sheep are more effective than goats as they can debark green alder without damaging other valuable plants.
JOURNAL OF APPLIED ECOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Enyew Negussie, Oscar Gonzalez-Recio, Mara Battagin, Ali-Reza Bayat, Tommy Boland, Yvette de Haas, Aser Garcia-Rodriguez, Philip C. Garnsworthy, Nicolas Gengler, Michael Kreuzer, Bjoern Kuhla, Jan Lassen, Nico Peiren, Marcin Pszczola, Angela Schwarm, Helene Soyeurt, Amelie Vanlierde, Tianhai Yan, Filippo Biscarini
Summary: This study compares the performance of machine learning algorithm random forest (RF) and multiple linear regression (MLR) models in predicting methane emissions from dairy cows. The results show that RF models outperform MLR models in accuracy when dry matter intake (DMI) is included in the model. Imputing missing data points improves prediction accuracy.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Food Science & Technology
R. Lugara, L. Realini, M. Kreuzer, K. Giller
Summary: This study found a sex-specific programming effect on offspring growth in response to maternal spirulina intake, but high energy intake had no effect. Spirulina intake did not affect meat quality, but it may improve the ratio of polyunsaturated fatty acids/saturated fatty acids in offspring meat.
Article
Food Science & Technology
M. Keller, M. Kreuzer, B. Reidy, A. Scheurer, B. Guggenbuhl, M. Luder, J. Frank, K. Giller
Summary: This study investigated the use of grass silage in intensive beef production. The results showed that grass silage did not significantly impair the growth performance and meat quality of cattle compared to maize silage. Moreover, increasing the proportion of grass silage in the diet improved meat tenderness and fatty acid profiles.
Article
Veterinary Sciences
M. Bertsch, M. Terranova, M. Kreuzer, M. Clauss
Summary: This study analyzed the particle size of Swiss pig feed and found that most of the feeds did not meet the recommended particle size. Wet sieving should be considered the standard analysis method, and material loss should be taken into account when calculating particle size.
SCHWEIZER ARCHIV FUR TIERHEILKUNDE
(2022)
Article
Agriculture, Dairy & Animal Science
M. Keller, A. Scheurer, B. Reidy, A. Liesegang, S. L. Amelchanka, K. Giller
Summary: Diets based on grassland-based feed are not common in intensive beef production, but they have potential benefits in terms of reducing nitrogen emissions and avoiding the need for additional protein sources. However, more research is needed to understand the effects of grassland-based diets on nitrogen and energy utilization as well as methane emissions.
Article
Green & Sustainable Science & Technology
Alejandro Belanche, Alexander N. Hristov, Henk J. van Lingen, Stuart E. Denman, Ermias Kebreab, Angela Schwarm, Michael Kreuzer, Mutian Niu, Maguy Eugene, Vincent Niderkorn, Cecile Martin, Harry Archimede, Mark McGee, Christopher K. Reynolds, Les A. Crompton, Ali Reza Bayat, Zhongtang Yu, Andre Bannink, Jan Dijkstra, Alex Chaves, Harry Clark, Stefan Muetzel, Vibeke Lind, Jon M. Moorby, John A. Rooke, Aurelie Aubry, Walter Antezana, Min Wang, Roger Hegarty, V Hutton Oddy, Julian Hill, Philip E. Vercoe, Jean Victor Savian, Adibe Luiz Abdalla, Yosra A. Soltan, Alda Lucia Gomes Monteiro, Juan Carlos Ku-Vera, Gustavo Jaurena, Carlos A. Gomez-Bravo, Olga L. Mayorga, Guilhermo F. S. Congio, David R. Yanez-Ruiz
Summary: This study developed empirical models to predict enteric methane emissions from sheep using a global database. The models showed that including variables such as body weight and organic matter digestibility improved prediction accuracy. Age-specific equations were also found to enhance prediction performance. The study concluded that predicting sheep methane production requires considering variables such as dry matter intake, body weight, and rumen propionate proportion, and appropriate universal equations can be used across different diets and climatic conditions.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Agriculture, Dairy & Animal Science
G. Lazzari, A. Munger, D. Heimo, J. Seifert, A. Camarinha-Silva, D. Borda-Molina, M. Zahner, S. Schrade, M. Kreuzer, F. Dohme-Meier
Summary: This study investigated the effects of Acacia mearnsii extract on nitrogen partitioning and ammonia volatilization in dairy cows. It found that the effects of Acacia were consistent regardless of the type of silage. However, Acacia supplementation resulted in a decrease in dry matter intake and milk production, while sainfoin supplementation resulted in lower organic matter digestibility.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Xiaoyu Zhang, Yang Li, Melissa Terranova, Sylvia Ortmann, Saskia Kehraus, Christian Gerspach, Michael Kreuzer, Marcus Clauss, Juergen Hummel
Summary: Sheep with low methane yield had shorter retention times. Pilocarpine, a saliva stimulant, was applied to sheep to reduce retention times and methane yield. Increasing pilocarpine dosage linearly decreased the retention times but did not affect feed intake or methane yield.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Article
Multidisciplinary Sciences
Amy Birkinshaw, Michael Sutter, Beat Reidy, Laurence Jungo, Stefanie Mueller, Michael Kreuzer, Melissa Terranova
Summary: This study aims to predict the proportion of grassland-based feeds in dairy cow diets using milk biomarkers. The associations between biomarkers and %GB were evaluated and quantified. The results show that certain fatty acids, color indices, and other biomarkers can be used to accurately predict %GB.
Article
Agriculture, Dairy & Animal Science
M. Heuel, M. Kreuzer, I. D. M. Gangnat, E. Frossard, C. Zurbrugg, J. Egger, B. Dortmans, M. Gold, A. Mathys, J. Jaster-Keller, S. Weigel, C. Sandrock, M. Terranova
Summary: Replacing soybeans with insects in egg and poultry meat production could improve environmental sustainability. This study assesses the transfer of contaminants from larval substrates to poultry-derived food. Despite the increase in cadmium and lead concentrations in chicken tissue, the levels in meat and eggs were below the maximum content, suggesting a lower risk than expected in poultry food chains.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
T. Zehnder, M. K. Schneider, A. Luscher, K. Giller, P. Silacci, J. Messadene-Chelali, J. Berard, M. Kreuzer
Summary: Climate and economic changes promote the encroachment of woody plants on marginal mountain pastures. In the Alps, the main woody invader is the nitrogen-fixing shrub Alnus viridis (green alder). Robust breeds of different ruminant species may perform well on these shrub-encroached pastures.
ANIMAL PRODUCTION SCIENCE
(2023)
