Article
Environmental Sciences
Ghanim Al-Thani, Adel Ehab Ibrahim, Mohammed Alomairi, Baher I. Salman, Mostafa M. Hegazy, Ahmed Al-Harrasi, Sami El Deeb
Summary: The use of weight loss herbal preparations is increasing due to the consumption of high-calorie junk food. However, the regulations governing the quality control of these products may be minimal. This study investigated the elemental contents in these products and found that some macro-elements were present at safe levels, while some micro-elements and other elements showed concerning levels. Stricter surveillance of herbal products is necessary.
Article
Biochemistry & Molecular Biology
Magdalena Ligor, Tomasz Kowalkowski, Boguslaw Buszewski
Summary: The main aim of this study was to analyze and quantify potentially toxic elements (PTEs) in honey from Poland. The honey samples from different parts of Poland were compared to samples from other countries. The results showed that most honey samples had moderate levels of PTEs, with only a few samples having higher concentrations of copper and manganese.
Article
Chemistry, Applied
Jiahui An, Zhao Liu, Gang Xie, Yi Zhu
Summary: The concentrations of 26 elements in imported and domestic infant cereals were evaluated and risk assessment was performed based on the measurements. For toxic elements, Cd and Pb had exceedance rates of 20% and 16.7% respectively, and all toxic elements showed ingestion risk. For potentially toxic elements, no detectable levels were obtained for Be, Co, Ga, Sb, and Tl. Only 10% of the samples indicated a potential health risk from long-term intake of Al. Despite better performance of domestic samples in essential elements like Na, Ca, and Zn, none of the elements fully met the intake requirements. The standards for complementary foods for infants and young children are not sufficiently regulated, and infant cereals as the first weaning food should receive more attention in terms of safety and nutritional properties, especially the potentially toxic elements.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Agronomy
Muhammad Moaaz Ali, Raheel Anwar, Muhammad Waleed Shafique, Ahmed Fathy Yousef, Faxing Chen
Summary: This study analyzed the effects of magnesium, zinc, and boron on the levels of various nutrients and heavy metals in loquat leaves and fruit tissues. The results showed that the application of these elements significantly influenced the mineral concentrations in loquats, while heavy metal concentrations in the fruits remained within safe limits for human consumption.
Article
Biochemistry & Molecular Biology
Semiha Kopru, Mehmet Cadir, Mustafa Soylak
Summary: Veganism, a diet that excludes animal foods, is gaining popularity worldwide. However, long-term adherence to a vegan diet may lead to nutrient and mineral deficiencies, impacting health. A study analyzed the trace element content in various vegan foods purchased from Turkey and found that the levels were below legal limits. These findings highlight the importance of considering nutrient intake in vegan nutrition.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2022)
Review
Chemistry, Medicinal
U. Holzgrabe
Summary: The presence of N-nitrosodialkylamines in pharmaceutical ingredients and drug products has raised concerns about the quality of drugs. It has been discovered that the quality control tests specified in international pharmacopoeias may not be sufficient. These N-nitrosodialkylamines are not limited by compendial tests, but by the ICH guideline M7 due to their mutagenic properties. Nitrosamine impurities related to the drug substances have been detected during the risk assessment process required by regulatory authorities. This review focuses on the formation, toxicity, and mitigation of these N-nitrosodialkylamine impurities.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2023)
Article
Materials Science, Multidisciplinary
Natalia A. Korotkova, Vasilisa B. Baranovskaya, Kseniya Petrova
Summary: In this article, an analytical procedure for the analysis of waste Sm-Co magnets was developed using ICP-MS and ICP-OES. The experimental parameters related to microwave digestion and acid concentrations were optimized. The matrix effect on the ICP-MS analysis and optimal instrumental parameters were investigated. The proposed method was validated through recovery tests and inter-method experiments.
Article
Biochemistry & Molecular Biology
Cezara Voica, Constantin Nechita, Andreea Maria Iordache, Carmen Roba, Ramona Zgavarogea, Roxana Elena Ionete
Summary: This study found that the daily intake of chromium and copper exceeded the recommended dietary allowances in many food items, and consuming nickel and copper through seeds and fruits could have adverse health effects. Additionally, a strong correlation between copper and arsenic was established. The cancer risk index for all elements investigated was within safe limits, indicating that lifetime consumption does not increase the risk of carcinogens.
Article
Food Science & Technology
Rui Azevedo, Ana Rafaela Oliveira, Agostinho Almeida, Ligia Rebelo Gomes
Summary: Gums and carrageenans are widely used food additives to improve texture and viscosity in food preparations. The content of trace elements in commercial products containing these additives was analyzed in this study. The consumption of these additives can contribute to the daily requirements of essential trace elements, but additional research is needed to assess the potential risk of introducing toxic trace elements.
Article
Engineering, Environmental
Mark Honti, Marton Zsugyel, Carolin Seller, Kathrin Fenner
Summary: This study developed the concept of persistence benchmarking for organic micropollutants in large rivers. By observing the dissipation rates of compounds, the researchers were able to distinguish between fast- and slow-degrading compounds and provide reasonable estimates on system half-lives.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Baljit Kaur, Palwinder Singh
Summary: This study compiles information about the application of the epoxide functional group in medicinal compounds and biochemical probes, and explores the related advantages and challenges. It also analyzes the strategies that have been adopted for the successful development of epoxide-based compounds within drug discovery programs.
BIOORGANIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Taiyu Wang, Hailong Yang, Jie Yang, Ningjie Guo, Guodong Wu, Xueyu Xu, Ming An
Summary: A novel UPLC-MS/MS method was developed for the identification and quantification of four potential genotoxic impurities in the active pharmaceutical ingredients of a novel P2Y(12) receptor antagonist. This validated method showed low limits of detection, excellent linearity, and satisfactory recovery range, making it highly practical for pharmaceutical quality control of TSD-1.
Review
Multidisciplinary Sciences
Anand S. Burange, Sameh M. Osman, Rafael Luque
Summary: This review discusses the advantages and disadvantages of flow chemistry in today's scenario and recent developments in flow devices. It primarily focuses on the recent advancements in the flow synthesis of pharmaceutically important products in the last five years, as well as the critical steps and new developments in the flow synthesis of selected compounds.
Article
Biochemistry & Molecular Biology
Davide Spanu, Alessandro Palestra, Veronica Prina, Damiano Monticelli, Simone Bonanomi, Sandro Usseglio Nanot, Gilberto Binda, Laura Rampazzi, Gianluca Sessa, David Callejo Munoz, Sandro Recchia
Summary: The unsuitability of microwave-assisted acid digestion followed by ICP-MS analysis for quantifying trace elements in ultrapure SiC was demonstrated due to contamination from memory effects of PTFE microwave vessels and the purity levels of acids. A new analytical protocol using LA-ICP-MS was found to be more effective, especially when the SiC samples were embedded in epoxy resin. The optimized protocol allows for accurate determination of elements at sub-mg/kg levels.
Article
Chemistry, Applied
Patrick J. Gray
Summary: A non-targeted convenience survey was conducted in 2021 to estimate the range of total arsenic (As), cadmium (Cd), total mercury (Hg), and lead (Pb) concentrations in ready-to-eat baby foods. The survey analyzed 400 samples purchased from both online and brick-and-mortar retail, including organic and non-organic products packaged in different materials. Results showed that foods containing rice were more likely to contain arsenic, while foods with leafy greens were more likely to contain cadmium, and foods with root vegetables had the highest concentrations of lead.
FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE
(2023)
Article
Environmental Sciences
Altevir Rossato Viana, Bruna Godoy Noro, Daniel Santos, Katianne Wolf, Yasmin Sudatti Das Neves, Rafael Noal Moresco, Aline Ferreira Ourique, Erico Marlon Moraes Flores, Cristiano Rodrigo Bohn Rhoden, Luciana Maria Fontanari Krause, Bruno Stefanello Vizzotto
Summary: This study investigated the phytochemical compositions and biological activities of Vassobia breviflora extract. The extract exhibited excellent antioxidant and antimicrobial activities, as well as cytotoxic effects against various tumor cells. Moreover, it also increased the production of reactive oxygen species.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
(2023)
Article
Chemistry, Analytical
Felipe A. Silva, Beatriz R. Rigui, Cristian R. Andriolli, Erico M. M. Flores, Paola A. Mello, Rochele S. Picoloto
Summary: A miniaturized liquid-liquid extraction (LLE) method was proposed for pre-concentration of Na, K, Ca, and Mg in crude oil. The method showed no statistical difference compared to the reference values, with relative standard deviations lower than 6%. The proposed miniaturized LLE method presents several advantages, such as ease-of-use, high throughput, and low limits of quantification, making it an environmentally friendly and cost-effective alternative for routine analyses.
Article
Chemistry, Analytical
Jaime S. Mandlate, Alessandra S. Henn, Paola A. Mello, Erico M. M. Flores, Juliano S. Barin, Fabio A. Duarte
Summary: A simple and fast sample preparation method called microwave-induced combustion in disposable vessels (MIC-DV) was developed for Cl and S determination in crude oil using ICP-OES. The method allows efficient digestion of up to 10 mg of crude oil per cycle, reaching a total sample mass of 50 mg.
ANALYTICA CHIMICA ACTA
(2023)
Article
Environmental Sciences
Jorge Osorio-Martinez, Luis F. F. Silva, Erico M. M. Flores, Gabriel T. T. Druzian, Jesus Olivero-Verbel
Summary: This study assessed the concentrations and toxicity of potentially toxic elements (PTEs) in urban dust from Barranquilla, Colombia. The results showed that the PTEs in the dust had negative effects on the physiological parameters of Caenorhabditis elegans, indicating that it can be used as a sensitive organism for warning systems related to biota risks associated with air pollution.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Food Science & Technology
Adrieni Santos de Oliveira, Bibiana Alves dos Santos, Carla Andressa Almeida Farias, Leticia Pereira Correa, Madison Willy Silva Cordeiro, Mariana Basso Pinton, Milene Teixeira Barcia, Roger Wagner, Alexandre Jose Cichoski, Juliano Smanioto Barin, Jose Manuel Lorenzo, Gema Nieto, Paulo Cezar Bastianello Campagnol
Summary: Hydrogelled emulsions (HEs) of linseed oil and pea protein (PP) were produced with raspberry extract obtained by a green extraction technique. The HEs were used to replace 50% of pork backfat in burgers. The reformulation showed benefits such as reduced fat content, improved PUFA ratio, increased cooking yield, and decreased oxidative defects.
Article
Food Science & Technology
Yasmim Sena Vaz Leaes, Jose Manuel Lorenzo, Ana Carolina Mendes Dias Seibt, Mariana Basso Pinton, Silvino Sasso Robalo, Renius De Oliveira Mello, Roger Wagner, Juliano Smanioto Barin, Cristiano Ragagnin De Menezes, Paulo Cezar Bastianello Campagnol, Alexandre Jose Cichoski
Summary: The effects of ultrasound on myoglobin modification, nitrous pigment formation, color, and sulfhydryl content in nitrite-free pork meat batter were investigated. It was found that ultrasound can enhance the red color of nitrite-free meat products.
Article
Food Science & Technology
Bibiana Alves dos Santos, Andrine Menna da Fontoura, Leticia Pereira Correa, Mariana Basso Pinton, Milena Padilha, Priscila Rossato Fracari, Stephanie Reis Ribeiro, Roger Wagner, Alexandre Jose Cichoski, Juliano Smanioto Barin, Paulo Cezar Bastianello Campagnol
Summary: This study examined the effects of reducing sodium nitrite by 50% and adding nisin (200 mg/kg) and different concentrations (0, 0.5%, 0.75%, and 1%) of jabuticaba peel extract (JPE) on the attributes of Bologna-type sausages. The modified treatments resulted in approximately 50% lower residual nitrite levels and showed color stability during storage. Physicochemical and sensory analyses indicated that JPE exhibited antioxidant activity comparable to sodium nitrite. The microbiological quality of the reformulated products was similar to the control, but further studies are needed to assess the impact on pathogenic microorganisms affected by nitrite.
Article
Multidisciplinary Sciences
Debora P. de Moraes, Daniele F. Ferreira, Carla Andressa A. Farias, Priscila Nehring, Milene T. Barcia, Alexandre Jose Cichoski, Juliano S. Barin
Summary: An ultrasound pretreatment was used to increase anthocyanins content in blackberry juice. The whole fruits were subjected to sonication without contact with any solvent, followed by pressing to extract the juice. The experimental results showed that 7 minutes of sonication at 65% amplitude increased the anthocyanin content in the juice from 31% to 56% for BRS Xingu, Guarani, and Xavante cultivars. The major anthocyanins, cyanidin-3-glucoside and cyanidin-3-rutinoside, were found in higher concentrations in sonicated fruits. Therefore, ultrasound pretreatment of whole fruits provides a simple, fast, and environmentally friendly approach to enhance anthocyanin levels in blackberry juices.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2023)
Article
Agronomy
Izaura Ceolin dos Santos, Sandra Kunde Schlesner, Debora Piovesan de Moraes, Daniele de Freitas Fereira, Monica Voss, Sandro Rogerio Giacomelli, Juliano Smanioto Barin
Summary: A smartphone-operated device was used to determine eugenol in clove essential oil. The method employed colorimetric reaction with Folin-Ciocalteu reagent and evaluated lighting conditions for direct image capture in 2 mL disposable vessels. The proposed method showed comparable accuracy with traditional methods and allowed for quick evaluation of multiple samples with minimal reagent use and waste generation.
Article
Chemistry, Analytical
Jussiane S. S. Silva, Graciela M. M. Heidrich, Bruno O. O. Poletto, Jose N. G. Paniz, Valderi L. L. Dressler, Erico M. M. Flores
Summary: A direct solid sampling method using ETV-ICP-MS was developed for determining mercury in bioresorbable calcium phosphate-based materials. The method involved fast sample heating with a halogen lamp, followed by vaporization and cooling steps. Mercury vaporized at a low temperature and did not co-vaporize the main matrix. External calibration using aqueous solutions was used for quantification. The method showed good accuracy, precision, and sample throughput, making it suitable for routine analyses.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Gustavo Rossato Bitencourt, Fabio Andrei Duarte, Valderi Luiz Dressler, Rodrigo Cordeiro Bolzan, Erico Marlon de Moraes Flores, Paola Azevedo Mello
Summary: A single method using chemical vapor generation coupled with microwave-induced plasma optical emission spectrometry was developed for the determination of As and Hg in dietary supplements. The method complied with the maximum concentration requirements set by the United States Pharmacopeia and showed no statistical difference compared to comparative methods. The proposed method can be considered an alternative for the quality control of As and Hg in dietary supplements.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Food Science & Technology
Vanessa Bordin Viera, Natieli Piovesan, Renius De Oliveira Mello, Juliano Smanioto Barin, Aline De Oliveira Fogaca, Cezar Augusto Bizzi, Erico Marlon De Moraes Flores, Ana Carolina Dos Santos Costa, Diego Elias Pereira, Juliana Kessia Barbosa Soares, Ernesto Hashime Kubota
Summary: This study determined the antioxidant activity of red onion peel extract using ultrasound extraction, and found that different ultrasound power and solvent concentration had varying effects on different antioxidant indicators.
JOURNAL OF CULINARY SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Michelle Buoso, Beatrice Campanella, Massimo Onor, Emanuela Pitzalis, Alessandro D'Ulivo
Summary: The use of BH intermediates as derivatization reagents significantly improves the tolerance to interference from transition metal ions in the generation of SbH3 and BiH3, and shows high tolerance in a wide range of acidity. The method has been successfully applied to the determination of Sb and Bi in complex samples, providing further understanding of the chemical behavior of borohydrides.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Chao-Feng Li, Xuan-Ce Wang, Zhu-Yin Chu, Peng Peng
Summary: Thermal ionization mass spectrometry (TIMS) is the standard method for obtaining precise Sr-87/Sr-86 isotopic ratios. However, our developed hydrofluoric acid coprecipitation method offers a low-cost, rapid, simple, and high-throughput alternative for analyzing red wine samples, effectively eliminating isobaric interference and matrix element inhibition.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Ivan B. Krstic, Bratislav M. Obradovic, Milorad M. Kuraica
Summary: This paper presents the spatio-temporal dynamics of a Grimm-type microsecond pulsed glow discharge (mu PGD) in argon at 6 mbar. The occurrence of a high current peak during the discharge ignition is analyzed and the importance of displacement current is emphasized. The development of electron excitation temperature for argon atoms and ions at various distances from the cathode is measured. The spatio-temporal evolution of selected spectral lines of argon and copper atoms and ions is analyzed during different phases of the discharge. The results suggest that the behavior of spectral line emissions differs between the pre-peak and afterglow periods, with different lines reaching maximum intensity during these phases. The appearance time and decay time of the afterpeak are shorter for ions than for atoms. These findings are explained in terms of three-body recombination processes and ion mobilities.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Qiuyun Wang, Anmin Chen, Xun Gao
Summary: In this paper, the combination of Tesla coil discharge (TCD) and laser-induced breakdown spectroscopy (LIBS) was used to enhance the emission of Al atomic lines and AlO molecular bands. The optimized distance between the TCD tip and the sample surface was found to be 5 mm, and the optimal laser energy was 25.1 mJ. Furthermore, TCD-SELIBS showed lower limits of detection (LoDs) for Cr and Pb elements compared to surface enhanced LIBS (SELIBS). The combination of TCD and LIBS is a promising technology for high-sensitivity analysis of heavy metals in water, with the advantages of simplicity, low cost, ease of operation, industrialization, and commercialization.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Analytical
Yanwen Tang, Tingguang Lan, Jianfeng Gao, Zhongjie Bai, Xiaowen Huang, Junjie Han, Na Liu
Summary: Titanium is an important metal widely used in various industries. Ilmenite minerals are the main source of titanium metal and can be found in igneous and metamorphic rocks as well as different types of deposits. To accurately determine U-Pb ages of ilmenite, a new calibration method and appropriate reference materials are urgently needed. Laser ablation sector field inductively coupled plasma mass spectrometry has been used to minimize matrix effects and zircon 91500 has been identified as a suitable reference material for measuring the Pb/U ratio in ilmenite. The direct calibration method using zircon 91500 as an external standard has been found to be effective for in situ U-Pb dating of ilmenite samples under different ablation settings.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)