Article
Plant Sciences
Xiao-Yi Li, Yun-Fang Hao, Zhan-Xi Hao, Jian-Guo Jiang, Qiang Liu, Qun Shen, Li Liu, Yan-Kui Yi, Chun-Yan Shen
Summary: CHL extracts may suppress lipid accumulation by inhibiting differentiation of 3T3-L1 cells and attenuating metabolic syndromes in HFD-fed mice.
Review
Nutrition & Dietetics
Dorottya Koncz, Barbara Toth, Muh Akbar Bahar, Orsolya Roza, Dezso Csupor
Summary: This study provides an overview of the safety and efficacy of p-synephrine and evaluates its weight loss effects through a meta-analysis. The findings suggest that prolonged use of synephrine may increase blood pressure, but it does not facilitate weight loss or affect body composition parameters. Further research is needed to confirm its safety and efficacy.
Article
Food Science & Technology
Zahra Panahi, Rahem Khoshbakht, Bahareh Javadi, Emadodin Firoozi, Niloufar Shahbazi
Summary: The study found that the sodium alginate-based edible coating containing citrus and lemon extracts had a significant effect on the chemical and antimicrobial properties of chicken meat. The coating exhibited antioxidant and antimicrobial activities, resulting in lower microbial counts and better overall acceptability of the coated samples.
JOURNAL OF FOOD QUALITY
(2022)
Article
Agricultural Engineering
Ibtissem Chakroun, Zied Bouraoui, Takwa Ayachi, Karim Hosni, Hamadi Guerbej, Mejdi Snoussi, Jamel Jebali, Tahar Gharred
Summary: This study investigated the phytochemical composition and bioactivities of polar and non-polar extracts from Tunisian Thomson Navel orange peels. The extracts exhibited promising antioxidant, antimicrobial, and cytotoxic effects, making them potential sources for developing natural agents.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Integrative & Complementary Medicine
Junjie Li, Cheng Gu, Kangkang Luo, Yu Li, Zhiyao Yuan, Xudong Wu, Xianmei Zhou, Xiaomin Lu
Summary: This study establishes a model of LPS-induced ARDS-related pulmonary fibrosis in mice and investigates the anti-fibrosis effects and molecular mechanisms of Citrus Alkaline Extracts (CAE) in vivo and in vitro. The results demonstrate that CAE effectively alleviates lung injury and fibrosis, reverses TGF-beta 1-induced epithelial-mesenchymal transition (EMT) through Wnt/beta-catenin, Stat3/6 and COX2/PGE2 signaling pathways. RNA-Seq analysis reveals important mechanisms of CAE's therapeutic effects, and network pharmacology analysis identifies potential core targets of CAE in EMT.
Article
Biochemistry & Molecular Biology
Ouijdane Benayad, Mohamed Bouhrim, Salima Tiji, Loubna Kharchoufa, Mohamed Addi, Samantha Drouet, Christophe Hano, Jose Manuel Lorenzo, Hasnae Bendaha, Mohamed Bnouham, Mostafa Mimouni
Summary: This study evaluated the peel of C. aurantium to be a valuable by-product rich in non-toxic phytoconstituents, particularly those with potential antidiabetic action. The research found that the peel extracts inhibited alpha-amylase and alpha-glycosidase in vitro, suggesting potential benefits for diabetes management. Additionally, the oral administration of C. aurantium extracts at a high dose did not show any signs of acute toxicity in mice, indicating their safety for consumption.
Article
Plant Sciences
Hossam S. El-Beltagi, Nareman S. Eshak, Heba Mohamed, Eslam S. A. Bendary, Amal W. Danial
Summary: This study evaluated the nutritional content, phytochemicals, antioxidant, and antibacterial properties of citrus and pomegranate peel. The results showed that pomegranate peel had higher mineral content and antioxidant activity, while citrus peel had higher protein and fat content. Pomegranate peel extracts exhibited stronger antibacterial and antioxidant effects, and citrus peel essential oil was predominantly composed of D-limonene. Cakes made with citrus and pomegranate peel showed higher antioxidant activity and nutritional value.
Article
Nutrition & Dietetics
Aleksandra Skoczek-Rubinska, Agata Muzsik-Kazimierska, Agata Chmurzynska, Prof Jaroslaw Walkowiak, Joanna Bajerska
Summary: This study found a negative association between eating frequency and self-reported snacking frequency with BMI and energy intake in postmenopausal women. There were differences in dietary composition of snacks between different weight groups, with normal-weight women having higher dietary fiber density in self-reported snacks.
Article
Food Science & Technology
Nancy Abril Estrada-Sierra, Gabriel Rincon-Enriquez, Judith Esmeralda Urias-Silvas, Sandra Daniela Bravo, Socorro Josefina Villanueva-Rodriguez
Summary: This study evaluates the effects of solvents nature, degrees of maturity, and harvest season on the extraction of bioactive compounds from sour orange. The results show that semi-mature sour oranges harvested in spring have the highest antioxidant capacity and total flavonoid content when extracted with methanol and water. Green sour oranges harvested in summer have the highest concentration of naringin, neohesperidin, and p-synephrine.
Article
Biotechnology & Applied Microbiology
Boualem Benamar-Aissa, Nadhir Gourine, Mohamed Ouinten, Mohamed Harrat, Adel Benarfa, Mohamed Yousfi
Summary: The aim of this study was to investigate the synergistic effects of binary and ternary combinations of extracts from A. campestris (AC), A. herba alba (AHA) and C. aurantium (CA) on antioxidant activities. Antioxidant activities of essential oils (EO) and phenolic extracts (PE) were determined using various assays. The results showed interesting dilution effects of CA on AC and AHA EOs, as well as synergistic effects of the extract combinations on DPPH, FRAP and ABTS assays.
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2023)
Article
Surgery
Mikiko Sakuraya, Keishi Yamashita, Michitaka Honda, Masahiro Niihara, Motohiro Chuman, Marie Washio, Kei Hosoda, Takeshi Naitoh, Yusuke Kumamoto, Naoki Hiki
Summary: This study found that early administration of a postoperative regimen containing branched-chain amino acids (BCAA) improved lean body mass (LBM) loss at 1 month after gastrectomy in gastric cancer patients.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
David Dreizin, Remberto Rosales, Guang Li, Hassan Syed, Rong Chen
Summary: In a retrospective analysis of 115 patients with bleeding pelvic fractures, incorporating 2D or 3D markers of body composition showed improved predictive performance compared to the original Baltimore CT prediction model, especially with the use of 3D parameters.
CANADIAN ASSOCIATION OF RADIOLOGISTS JOURNAL-JOURNAL DE L ASSOCIATION CANADIENNE DES RADIOLOGISTES
(2021)
Article
Integrative & Complementary Medicine
Xiaoming Pan, Yinger Gu, Xian Zhang, Biwei Shi, Long Cui, Fangfang Wang, Fan Qu
Summary: BSTJF may help PCOS patients to achieve better outcomes in IVF by increasing the number of retrieved and fertilized oocytes, and improving clinical pregnancy rate, live birth rate, and term delivery rate. BSTJF also significantly reduces AMH levels in follicular fluids.
INTEGRATIVE MEDICINE RESEARCH
(2022)
Article
Genetics & Heredity
Fangfang Zhang, Liying Ying, Qing Zhang, Fangfang Wang, Fan Qu
Summary: Maternal PCOS is associated with an increased risk of developing obesity in female offspring.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2022)
Correction
Genetics & Heredity
Fangfang Zhang, Liying Ying, Qing Zhang, Fangfang Wang, Fan Qu
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2022)
Article
Multidisciplinary Sciences
Yan Wu, Yuhang Zhu, Ningning Xie, Hui Wang, Fangfang Wang, Jue Zhou, Fan Qu
Summary: This study investigates the molecular mechanism of the Chinese herbal medicine Qu's formula (QUF) in treating and preventing the recurrence of endometriosis. Through network pharmacology and molecular docking, the study identifies potential targets and signaling pathways related to endometriosis and confirms the therapeutic effects of active compounds in QUF. The findings provide a foundation for further experimental research.
Review
Obstetrics & Gynecology
Leyi Fu, Ningning Xie, Fan Qu, Jue Zhou, Fangfang Wang
Summary: This study conducted a systematic review and meta-analysis to investigate the association between polycystic ovary syndrome (PCOS) and metabolic syndrome (MetS) in adolescents. The results showed that adolescents with PCOS were more than three times as likely to have MetS compared to controls. Obese adolescents with PCOS also had a higher risk of MetS compared to those with obesity but without PCOS. Blood pressure and lipid metabolism were found to be affected in adolescents with PCOS, indicating that PCOS could increase the frequency of MetS by influencing these factors independent of obesity.
REPRODUCTIVE SCIENCES
(2023)
Article
Endocrinology & Metabolism
Lijie Jiang, Li Tian, Jiajia Yuan, Xinjie Xu, Fan Qu, Rong Zhang, Jianliu Wang
Summary: This study explored the associations between autistic traits and sex hormone changes in patients with polycystic ovary syndrome (PCOS), as well as the influence of parental autistic traits and related sex hormone changes on autistic traits in their offspring. The results showed that PCOS patients had more autistic traits, which may be related to elevated levels of testosterone and luteinizing hormone and decreased levels of progesterone. Additionally, the autistic traits in the offspring of PCOS patients were associated with higher maternal delivery age and a tendency towards autism traits.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Integrative & Complementary Medicine
Xinyi Zheng, Fangfang Wang, Chang Liu, Jianghong Gu, Yuhang Zhu, Jue Zhou, Fan Qu
Summary: This systematic review and meta-analysis evaluated the effects and safety of Chinese Herbal Medicine (CHM) on ovarian function in patients with endometriosis. The results showed that CHM can improve ovarian function by increasing estradiol (E2) levels, regardless of whether surgery is performed or not. Further high-quality clinical trials are needed to support this conclusion.
EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
(2022)
Article
Medicine, General & Internal
Yuhang Zhu, Fangfang Wang, Jue Zhou, Shuiqin Gu, Lianqing Gong, Yaoyao Lin, Xiaoli Hu, Wei Wang, Aihua Zhang, Dongmei Ma, Chunxiao Hu, Yan Wu, Lanzhong Guo, Limin Chen, Leiyin Cen, Yan He, Yuqing Cai, Enli Wang, Honglou Chen, Jing Jin, Jinhe Huang, Meiyuan Jin, Xiujuan Sun, Xiaojiao Ye, Linping Jiang, Ying Zhang, Jian Zhang, Junfei Lin, Chunping Zhang, Guofang Shen, Wei Jiang, Liuyan Zhong, Yuefang Zhou, Ruoya Wu, Shiqing Lu, Linlin Feng, Hong Guo, Shanhu Lin, Qiaosu Chen, Jinfang Kong, Xuan Yang, Mengling Tang, Chang Liu, Fang Wang, Xiao-Yang Mio Hu, Hye Won Lee, Xinfen Xu, Rong Zhang, Nicola Robinson, Myeong Soo Lee, Jisheng Han, Fan Qu
Summary: This multicenter randomized clinical trial in China showed that acupoint hot compress may reduce postpartum urinary retention, alleviate uterine contraction pain, improve depressive symptoms, and increase breastfeeding milk volume.
Article
Obstetrics & Gynecology
Jinghua Zhang, Manman Pan, Qing Zhang, Fangfang Wang, Fan Qu
Summary: This study aimed to explore the correlation between serum levels of tumor markers (CA125, AFP, and CEA) and total testosterone (TTE) in patients with polycystic ovary syndrome (PCOS). The results showed that CA125 levels were significantly lower and negatively correlated with TTE levels in PCOS patients, while AFP and CEA levels were significantly higher.
CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Lu Chen, Hong Wen, Yuhang Zhu, Fangfang Wang, Li Zhao, Qiongxin Liang, Fan Qu
Summary: In this study, the researchers investigated the relevance of miR-373-3p in the occurrence of sIUGR. They found that miR-373-3p can restrict the growth and migration of HTR8 trophoblast cells by targeting SLC38A1. The findings suggest that miR-373-3p could be used for the diagnosis and treatment of sIUGR.
Article
Integrative & Complementary Medicine
Yuhang Zhu, Yan Wu, Hao Zhang, Yanfei Zhao, Yule Ren, Wei Hu, Pan Li, Huiyi Wang, Ying Wang, Boda Zhang, Yujie Wang, Hongwen Yuan, Jiping Zhang, Wenqiang Li, Yufang Zhao, Jie Zhao, Yedong Shi, Yanye Shu, Xiao Zhang, Yan Sun, Sheng Yu, Ling Yang, Zhenbo Geng, Jiali Chen, Kun Lv, Weilin Wang, Wenjuan Xue, Yinger Gu, Fangfang Wang, Xiangrong Xu, Fan Qu
Summary: This study analyzed the perceptions of international students and teachers on how to improve international learning of Traditional Chinese Medicine (TCM). The results showed that integrating Chinese culture into TCM courses, comparing traditional medicine from different countries with TCM, using case reports as a teaching method, and emphasizing clinical practice and modern research on TCM are crucial for enhancing the learning experience of international undergraduate students majoring in conventional medicine.
INTEGRATIVE MEDICINE RESEARCH
(2022)
Review
Clinical Neurology
Xinyi Zheng, Zheng Zhu, Juan Chen, Jiaying He, Yuhang Zhu, Lei Zhang, Fan Qu
Summary: This systematic review and meta-analysis found that cognitive behavioural therapy for insomnia (CBT-I) significantly improved sleep quality, insomnia severity, anxiety, and depression in pregnant women. The findings provide evidence for the validity of CBT-I in treating insomnia or sleep disturbances during pregnancy.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Plant Sciences
Qing Zhang, Jun Ren, Fangfang Wang, Mingqian Li, Manman Pan, Hui Zhang, Fan Qu
Summary: This study investigated the mechanism of a Chinese herbal medicine, Bu-Shen-Tian-Jing Formula, in treating polycystic ovary syndrome (PCOS). The results showed that the herbal medicine effectively alleviated the pathogenesis of PCOS by reducing oxidative stress and improving glucose metabolism.
Editorial Material
Integrative & Complementary Medicine
Jue Zhou, Weihuan Hu, Fan Qu
INTEGRATIVE MEDICINE RESEARCH
(2022)
Article
Multidisciplinary Sciences
Jue Zhou, Zhou Jiang, Leyi Fu, Fan Qu, Minchen Dai, Ningning Xie, Songying Zhang, Fangfang Wang
Summary: The study aimed to identify molecular subtypes and related genes associated with preterm labor risk in women with polycystic ovary syndrome (PCOS). Through analysis of multiple gene expression datasets, two molecular subtypes were identified in PCOS patients, and key genes related to preterm labor were determined. These findings help uncover the heterogeneity of clinical pregnancy complications in women with PCOS.
