Investigations on dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and the corresponding monomers and dendrons with ethacrynic acid motifs

Generation dependent cancer targeting potential of poly(propyleneimine) dendrimer

(2014) Prashant Kesharwani et al.   BIOMATERIALS

How to study dendrimers and dendriplexes III. Biodistribution, pharmacokinetics and toxicity in vivo

(2014) Dzmitry Shcharbin et al.   JOURNAL OF CONTROLLED RELEASE

Expand classical drug administration ways by emerging routes using dendrimer drug delivery systems: A concise overview

(2013) Serge Mignani et al.   ADVANCED DRUG DELIVERY REVIEWS

Menadione and ethacrynic acid inhibit the hypoxia-inducible factor (HIF) pathway by disrupting HIF-1α interaction with p300

(2013) Yu-Ran Na et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dendrimer Space Exploration: An Assessment of Dendrimers/Dendritic Scaffolding as Inhibitors of Protein–Protein Interactions, a Potential New Area of Pharmaceutical Development

(2013) Serge Mignani et al.   CHEMICAL REVIEWS

Ethacrynic Acid Oxadiazole Analogs Induce Apoptosis in Malignant Hematologic Cells through Downregulation of Mcl-1 and c-FLIP, Which Was Attenuated by GSTP1-1

(2013) G. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Original Multivalent Copper(II)-Conjugated Phosphorus Dendrimers and Corresponding Mononuclear Copper(II) Complexes with Antitumoral Activities

(2013) Nabil El Brahmi et al.   MOLECULAR PHARMACEUTICS

Dendrimers as macromolecular tools to tackle from colon to brain tumor types: a concise overview

(2013) Serge Mignani et al.   NEW JOURNAL OF CHEMISTRY

Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

(2013) E. Blattes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendrimer space concept for innovative nanomedicine: A futuristic vision for medicinal chemistry

(2013) Serge Mignani et al.   PROGRESS IN POLYMER SCIENCE

6r, a novel oxadiazole analogue of ethacrynic acid, exhibits antitumor activity both in vitro and in vivo by induction of cell apoptosis and S-phase arrest

(2012) Peng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

The synthesis of ethacrynic acid thiazole derivatives as glutathione S-transferase pi inhibitors

(2012) Ting Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In vivo efficacy of the diuretic agent ethacrynic acid against multiple myeloma

(2012) Young Kim et al.   LEUKEMIA RESEARCH

Association of Chemotherapeutic Drugs with Dendrimer Nanocarriers: An Assessment of the Merits of Covalent Conjugation Compared to Noncovalent Encapsulation

(2012) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Solution-phase parallel synthesis and screening of anti-tumor activities from fenbufen and ethacrynic acid libraries

(2011) Yuan-Hsiao Su et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multifunctional dendritic polymers in nanomedicine: opportunities and challenges

(2011) Jayant Khandare et al.   CHEMICAL SOCIETY REVIEWS

Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma

(2011) Ilaria Zanellato et al.   ChemMedChem

Degradable Self-Assembling Dendrons for Gene Delivery: Experimental and Theoretical Insights into the Barriers to Cellular Uptake

(2011) Anna Barnard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphorus Dendrimers Affect Alzheimer’s (Aβ1–28) Peptide and MAP-Tau Protein Aggregation

(2011) Tomasz Wasiak et al.   MOLECULAR PHARMACEUTICS

Dendrimer therapeutics: covalent and ionic attachments

(2011) Saïd El Kazzouli et al.   NEW JOURNAL OF CHEMISTRY

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2010) R. A. Stahel et al.   ANNALS OF ONCOLOGY

Ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit—Potential anti-metastatic drugs

(2010) Romy F.J. Janser et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibitory effects of ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit and para-acylated phenols on human cancer cells

(2010) Zack E. Bryant et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine

(2010) Didier Astruc et al.   CHEMICAL REVIEWS

Biomedical applications of dendrimers: a tutorial

(2010) Meredith A. Mintzer et al.   CHEMICAL SOCIETY REVIEWS

Novel Oxadiazole Analogues Derived from Ethacrynic Acid: Design, Synthesis, and Structure−Activity Relationships in Inhibiting the Activity of GlutathioneS-Transferase P1-1 and Cancer Cell Proliferation

(2010) Xinmei Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dendrimers as therapeutic agents: a systematic review

(2010) Virendra Gajbhiye et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Prevalence of in vitro chemotherapeutic drug resistance in primary malignant pleural mesothelioma: Result in a cohort of 203 resection specimens

(2010) Aneil A. Mujoomdar et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Biological properties of phosphorus dendrimers

(2010) Anne-Marie Caminade et al.   NEW JOURNAL OF CHEMISTRY

Combining a Solution-Phase Derived Library with In-Situ Cellular Bioassay: Prompt Screening of Amide-Forming Minilibraries Using MTT Assay

(2009) Li-Wu Chiang et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Dendrimers as Carriers for Delivery of Chemotherapeutic Agents

(2009) Scott H. Medina et al.   CHEMICAL REVIEWS

Areneruthenium complexes as anticancer agents

(2009) Georg Süss-Fink   DALTON TRANSACTIONS

Dendrimers: Emerging polymers for drug-delivery systems

(2009) Basavaraj K. Nanjwade et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Ethacrynic Acid Exhibits Selective Toxicity to Chronic Lymphocytic Leukemia Cells by Inhibition of the Wnt/β-Catenin Pathway

(2009) Desheng Lu et al.   PLoS One

Therapeutic and diagnostic applications of dendrimers for cancer treatment☆

(2008) J WOLINSKY et al.   ADVANCED DRUG DELIVERY REVIEWS

Amide derivatives of ethacrynic acid: Synthesis and evaluation as antagonists of Wnt/β-catenin signaling and CLL cell survival

(2008) Guangyi Jin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dendrimers as Biopharmaceuticals: Synthesis and Properties

(2008) Carolina Villalonga-Barber et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY