Article
Biophysics
Arianna Balestri, Laure Gibot, Heinz Amenitisch, Lorenzo Cervelli, Costanza Montis, Barbara Lonetti, Debora Berti
Summary: Lipid cubic nanoparticles stabilized by PDMA-b-PNIPAM exhibit promising drug delivery properties, with enhanced uptake efficiency and improved treatment efficacy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Review
Biotechnology & Applied Microbiology
Shindu C. Thomas, Jin-Woo Kim, Giovanni M. Pauletti, Daniel J. Hassett, Nalinikanth Kotagiri
Summary: This review provides an update on the strategies utilizing exosomes for theranostic applications in nanomedicine, and discusses their features, modifications, and opportunities and limitations for targeted drug delivery in personalized nanotherapy.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Natalia Vtyurina, Christoffer Aberg, Anna Salvati
Summary: Live cell imaging is a powerful tool for understanding how nano-sized objects are taken up and trafficked by cells. The study found high variability in intracellular trafficking kinetics between individual cells and how nanoparticle properties affect cellular uptake and intracellular distribution kinetics.
Article
Biotechnology & Applied Microbiology
Adriano P. Pontes, Steffen van der Wal, Saketh R. Ranamalla, Karin Roelofs, Ioan Tomuta, Laura B. Creemers, Jaap Rip
Summary: Disulfide-containing poly(amidoamine) (PAA) has been studied as a potential nanocarrier for mRNA delivery. In this study, PEG-coated NPs showed improved transfection efficiency and stability compared to uncoated NPs. The intracellular reducing environment, specifically glutathione (GSH) concentrations, affected mRNA translation. Optimization of polymer-to-RNA loading ratios and dosages resulted in high transfection efficiency without toxic effects.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Polymer Science
Bahareh Farasati Far, Mohammad Reza Naimi-Jamal, Maryam Safaei, Kimia Zarei, Marzieh Moradi, Hamed Yazdani Nezhad
Summary: Natural polymer-based hydrogels have shown great potential and applications in drug delivery systems. Polysaccharides can cross-link with other molecules to form hydrogels, enabling targeted drug delivery. Hydrogels, as adjustable biomedical devices, have wide applications in the field of pharmaceuticals and biomedical engineering.
Article
Nanoscience & Nanotechnology
Michal Gorzkiewicz, Monika Marcinkowska, Maciej Studzian, Iwona Karwaciak, Lukasz Pulaski, Barbara Klajnert-Maculewicz
Summary: This study developed an innovative nanocarrier based on PAMAM dendrimer to increase the concentration of mesalazine in intestinal epithelial cells, thereby enhancing its anti-inflammatory potential. The covalent PAMAM-mesalazine conjugate was synthesized and characterized, and it was found that the drug successfully attached to the dendrimer. The use of PAMAM as a carrier improved cellular uptake and anti-inflammatory activity of mesalazine.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Review
Engineering, Biomedical
Timea B. B. Gandek, Luke van der Koog, Anika Nagelkerke
Summary: A key aspect for successful drug delivery via lipid-based nanoparticles is their internalization in target cells. Liposomes and EVs are the two prominent examples of such drug delivery systems. This review evaluates the internalization mechanisms of liposomes and EVs, as well as their intracellular fate. Opportunities to enhance the therapeutic efficacy of these systems are highlighted by tweaking these internalization mechanisms and intracellular fates.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Negar Hassani Besheli, Juul Verbakel, Maryam Hosseini, Lea Andree, Ben Joosten, X. Frank Walboomers, Alessandra Cambi, Fang Yang, Sander C. G. Leeuwenburgh
Summary: Mesoporous bioactive glass nanoparticles (MBGNs) have gained attention as multi-functional nanocarriers for bone-reconstructive and-regenerative surgery. This study investigated the influence of surface charge of Cu-doped MBGNs on cellular uptake by macrophages and pre-osteoblast cells. The results showed that cellular uptake of nanoparticles is a complex process influenced by multiple factors.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Tina Briolay, Tacien Petithomme, Morgane Fouet, Nelly Nguyen-Pham, Christophe Blanquart, Nicolas Boisgerault
Summary: This review provides an overview of recent advances in nanovectors for delivering anticancer molecules, including chemically engineered nanoparticles, cell-derived extracellular vesicles, and micro-organism-derived oncolytic viruses. It discusses their potential use in various anticancer therapies and the importance of personalized modifications for efficient and specific delivery.
Article
Polymer Science
Behzad Bolandi, Rana Imani, Shahin Bonakdar, Hossein Fakhrzadeh
Summary: The study focuses on developing a composite injectable hydrogel that can support cartilage regeneration by capturing cells and growth factors. The fabricated hydrogel, incorporating platelet rich plasma encapsulated microbeads, shows sustained release of growth factors and promotes tissue regeneration.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Yasunari Matsuzaka, Ryu Yashiro
Summary: Extracellular vesicles (EVs), such as exosomes, mediate intercellular communication by delivering their contents to distant target cells. EVs, especially exosomes with programmed death-ligand 1 (PD-L1), are implicated in cancer progression. Additionally, exosomes can be used as drug delivery systems by modifying their membrane peptides. This review focuses on the molecular docking and intracellular translocation of exosomes, highlighting their potential as an efficient drug-delivery system and therapeutic strategy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Qi Zhan, Kaikai Yi, Xueping Li, Xiaoteng Cui, Eryan Yang, Ning Chen, Xubo Yuan, Jin Zhao, Xin Hou, Chunsheng Kang
Summary: This study demonstrated the importance of engineering exosomal lipids to enhance cancer cellular uptake, leading to improved tumor cell internalization and increased anti-tumor activity in vitro.
MACROMOLECULAR BIOSCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Gagandeep Singh, Gaya S. Dasanayake, Claylee M. Chism, Priyavrat Vashisth, Amandeep Kaur, Sandeep Kumar Misra, Joshua S. Sharp, Eden E. L. Tanner
Summary: Achieving safe and efficacious drug delivery remains a challenge, and this study presents a promising approach using biocompatible GBILs to modify the surface of PLGA nanoparticles. The modified nanoparticles showed enhanced uptake by breast cancer cells and could potentially serve as a versatile platform for targeted drug delivery and gene therapy applications.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Review
Chemistry, Multidisciplinary
Valeria Rahamim, Aharon Azagury
Summary: This review provides an overview of noninvasive biomimetic, bioinspired, and bioengineered drug delivery systems, highlighting their importance, applications, challenges, and future research directions. It discusses the various methods and strategies employed, inconsistencies in terminology, advantages and limitations of different delivery systems, and the unique physiology and hurdles in mass transport of related tissues. Additionally, it addresses the novelty and origins of these paradigms in noninvasive drug delivery and proposes potential areas for further research.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Ceren Kimna, Theresa Monika Lutz, Hongji Yan, Jian Song, Thomas Crouzier, Oliver Lieleg
Summary: A nanoparticle-based drug delivery system has been designed to release therapeutic agents into disease cells based on specific DNA sequences, showing potential for targeted treatments of specific diseases.
Article
Chemistry, Multidisciplinary
Mahsa Sedighi, Zahra Mahmoudi, Alireza Ghasempour, Mehdi Shakibaie, Fahimeh Ghasemi, Mahsa Akbari, Samin Abbaszadeh, Ebrahim Mostafavi, Helder A. Santos, Mohammad-Ali Shahbazi
Summary: Inspired by natural resources, glycopolypeptide biopolymers have emerged as a new form of biopolymers in biomedical applications. They have well-defined secondary structures and pendant glycosides, and the ability to self-assemble into diverse structures. The nanostructures of glycopolypeptides have opened up new perspectives in drug delivery, diagnosis, and regenerative medicine due to their stable three-dimensional structures, high drug loading efficiency, excellent biocompatibility, and biodegradability.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Engineering, Electrical & Electronic
Mohammad Shahbazi, Mohammad Reza Khanlary, Anahita Taherkhani
Summary: In this study, molybdenum disulfide (MoS2) nanostructures were prepared using spray pyrolysis. The optical and structural properties of the prepared samples were characterized using various spectroscopic techniques. The transparency of the films prepared was observed through the transmission spectrum. The efficiency of silicon photovoltaic cells was enhanced by the deposition of MoS2 layer, with the highest efficiency of 11.9% achieved when the MoS2 layer was annealed at 500 degrees C in an argon gas environment.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Plant Sciences
Leila Mirjani, Azam Salimi, Maryam Shahbazi, Mohammad-Reza Hajirezaei, Mohammad Matinizadeh, Khadijeh Razavi, Seyed Mohsen Hesamzadeh Hejazi
Summary: The role of phytohormones in the acclimation of micropropagated plantlet inoculated with AM was investigated. The results showed that the concentrations of IAA and cis-zeatin increased, while ABA concentration decreased. AM was found to reduce transition stress by modifying ABA and jasmonate concentrations.
JOURNAL OF PLANT PHYSIOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Tomas Bauleth-Ramos, Nesma El-Sayed, Flavia Fontana, Maria Lobita, Mohammad-Ali Shahbazi, Helder A. Santos
Summary: Dissolving microneedles (dMNs) are water-soluble polymer drug delivery systems that have become popular for transdermal drug delivery. They offer advantages such as fast dissolution, short application time, and no biohazard risk, making them suitable for various biomedical and pharmaceutical applications. The formulation of successful dMNs requires careful consideration of patch design, needles geometry, polymer composition, method of formation, and payloads, as these factors directly affect the mechanical properties and efficacy of the microneedles. This review serves as a guide for dMN formulation, discussing the challenges at each step and strategies to optimize their administration and drug release.
Article
Nanoscience & Nanotechnology
Tiago Carvalho, Raquel Bartolo, Sonia N. Pedro, Bruno F. A. Valente, Ricardo J. B. Pinto, Carla Vilela, Mohammad-Ali Shahbazi, Helder A. Santos, Carmen S. R. Freire
Summary: Biopolymeric injectable hydrogels have been developed for myocardial regeneration applications, but they usually lack desired functionalities. In this study, gold nanoparticles (AuNPs) were synthesized using lysozyme nanofibrils (LNFs) as nanotemplates and incorporated into gelatin-hyaluronic acid (HA) hydrogels. The resulting nanocomposite hydrogels showed improved properties such as rheological properties, mechanical resilience, antioxidant activity, and electrical conductivity. The presence of AuNPs also allowed the hydrogels to be monitorable through computer tomography. This work demonstrates the excellent potential of LNFs and AuNPs@LNFs for formulating functional injectable biopolymeric nanocomposite hydrogels for myocardial regeneration applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Pei Zhang, Yingxin Liu, Guobing Feng, Cong Li, Jun Zhou, Chunyang Du, Yuancheng Bai, Shuai Hu, Tianhe Huang, Guan Wang, Peng Quan, Jouni Hirvonen, Jin Fan, Helder A. Santos, Dongfei Liu
Summary: Microparticles with ultrahigh drug loading and zero-order release of protein payloads are successfully engineered through controlled interfacial self-assembly of polymers. Protein molecules are transformed into nanoparticles covered with a polymer layer to improve their miscibility with carrier materials. The resulting microparticles achieve superior encapsulation efficiency and controlled payload release, enabling efficient glycemic control in type 1 diabetes.
ADVANCED MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Monica Terracciano, Simas Rackauskas, Andrea Patrizia Falanga, Sara Martino, Giovanna Chianese, Francesca Greco, Gennaro Piccialli, Guido Viscardi, Luca De Stefano, Giorgia Oliviero, Nicola Borbone, Ilaria Rea
Summary: The physicochemical properties of three different ZnO tetrapodal nanostructures (ZnO-Ts) synthesized by a combustion process were studied and evaluated for label-free biosensing purposes. The chemical reactivity of ZnO-Ts was explored by quantifying the available functional hydroxyl groups (-OH) on the transducer surface necessary for biosensor development. The best ZnO-T sample was chemically modified and bioconjugated with biotin as a model bioprobe, confirming their suitability for biosensing applications through streptavidin target detection experiments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Medicinal
Domenica Capasso, Paola Marino, Sonia Di Gaetano, Nicola Borbone, Monica Terracciano, Roberta Trani, Caterina Longo, Vincenzo Piccialli
Summary: Several five-membered bromolactones were synthesized from D-xylonolactone and D-ribonolactone, which are related to the C1-C5 portion of mycalin A lactone. The bromination of D-ribonolactone with HBr/AcOH, without transesterification, resulted in the majority of the acetylated lactones investigated. The evaluation of their anti-tumor activity indicated that the acetates possess cytotoxicity towards multiple cancer cells, with selectivity towards tumor cells and limited toxicity on healthy cells.
Review
Polymer Science
Mahsa Sedighi, Neha Shrestha, Zahra Mahmoudi, Zahra Khademi, Alireza Ghasempour, Hamideh Dehghan, Seyedeh Fahimeh Talebi, Maryam Toolabi, Veronique Preat, Bozhi Chen, Xindong Guo, Mohammad-Ali Shahbazi
Summary: Self-assembly is a growth mechanism in nature to form minimum energy structures through local interactions. Self-assembled peptides can design and fabricate various structures using physical interactions between building blocks. Peptide hydrogels, with bioactivity, biocompatibility and biodegradability, have versatile applications in biomedical fields such as drug delivery, tissue engineering, biosensing, and disease treatment.
Article
Chemistry, Multidisciplinary
Lingshuang Wang, Lian Duan, Ga Liu, Jianfeng Sun, Mohammad-Ali Shahbazi, Subhas C. C. Kundu, Rui L. L. Reis, Bo Xiao, Xiao Yang
Summary: Polyacrylic acid (PAA) and its derivatives are commonly used as matrices in wound dressings, but their weak wet adhesion limits their clinical application. In this study, a PAA-based coacervate hydrogel with strong wet adhesion capability is created by mixing PAA copolymers with isoprenyl oxy poly(ethylene glycol) ether and tannic acid. The coacervate exhibits solid adhesion to both dry and wet substrates, with an adhesive strength to skin of 23.4 kPa and 70% adhesion underwater. It also possesses desirable self-healing and extensible properties, making it suitable for joints that undergo frequent movement. The coacervate demonstrates antibacterial activity, facilitates fibroblast migration, modulates macrophage polarization, shortens hemostatic time, and promotes collagen deposition, angiogenesis, and epithelialization, suggesting its promising potential as a wound dressing in medical translation.
Review
Pharmacology & Pharmacy
Samin Abbaszadeh, Vahideh Nosrati-Siahmazgi, Kiyan Musaie, Saman Rezaei, Mostafa Qahremani, Bo Xiao, Helder A. Santos, Mohammad-Ali Shahbazi
Summary: Novel transplantation techniques are being developed to preserve the function of impaired tissues or organs. However, current technologies face challenges such as graft rejection by the immune system and the need for long-term immunosuppression. Thus, the development of biomaterial-based immunoengineering strategies has gained attention as a potential solution.
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Huijie Han, Jie Chen, Jiachen Li, Alexandra Correia, Raquel Bartolo, Mohammad-Ali Shahbazi, Tambet Teesalu, Shiqi Wang, Wenguo Cui, Helder A. Santos
Summary: Apoptosis is a programmed cell death process responsible for abnormal cell clearance. Cancer cells often develop mechanisms to escape apoptosis, posing a challenge in cancer treatment. A biomimetic lipid nanocarrier that mimics mitochondrial Cytochrome C binding has been developed. This nanocarrier shows great potential in pro-apoptosis cancer therapy, reducing ATP level and promoting apoptosome assembly, leading to higher apoptosis and anti-tumor efficacy.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Engineering, Biomedical
Congcong Yu, Xiaozhang Ying, Mohammad-Ali Shahbazi, Linjun Yang, Zaiqiang Ma, Lin Ye, Wentao Yang, Rongtai Sun, Tianyuan Gu, Ruikang Tang, Shunwu Fan, Shasha Yao
Summary: Conductive nano-materials and electrical stimulation can be used for synergetic therapy in ordinary excitable tissue repair. In this study, a novel nano-conductive hydrogel was synthesized for electro-inspired bone tissue regeneration. The hydrogel demonstrated excellent electroactivity, biocompatibility, and osteoinductivity, and had the potential to enhance cellular functionality by activating the TGF-beta/Smad2 signaling pathway. In vivo experiments showed that the nano-conductive hydrogel with electrical stimulation significantly promoted electro-inspired bone defect regeneration.
Review
Medicine, Research & Experimental
Roshanak Amirian, Mehdi Azadi Badrbani, Hossein Derakhshankhah, Zhila Izadi, Mohammad-Ali Shahbazi
Summary: Parkinson's disease is a neurodegenerative disorder characterized by the misfolding and aggregation of α-synuclein. Targeted Protein Degradation is an emerging approach that shows promise in treating Parkinson's disease by selectively breaking down specific proteins.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Engineering, Chemical
Yun Hao Feng, Wei Xin Guo, Xiaobin Li, Jiahui Liu, Vahideh Nosrati-Siahmazgi, Maryam Toolabi, Wen Min Fei, Yong Cui, Bo Zhi Chen, Mohammad-Ali Shahbazi, Li Juan Zhang, Can Yang Zhang, Xin Dong Guo
Summary: Nanovesicles have been widely studied and used in biomedical applications, but premature leakage of water-soluble drugs hinders their clinical use. Developing effective strategies to prevent leakage is crucial. In this study, we utilized coarse-grained molecular simulations to explore strategies for leakage inhibition. We investigated the effects of cholesteryl hemisuccinate doping and gold nanoparticles on the morphology and structure of nanovesicles. Our findings suggest that cholesteryl hemisuccinate can improve hole defects in the hydrophobic layer, adjusting drug diffusion. Additionally, we studied the effects of particle size, concentration, and surface chemical properties of gold nanoparticles on drug leakage. Physical cross-linking of gold nanoparticles led to increased drug leakage, but surface modification improved dispersion and reduced side effects.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Laetitia Bardet, Herve Roussel, Stefano Saroglia, Masoud Akbari, David Munoz-Rojas, Carmen Jimenez, Aurore Denneulin, Daniel Bellet
Summary: The thermal instability of silver nanowires leads to increased electrical resistance in AgNW networks. Understanding the relationship between structural and electrical properties of AgNW networks is crucial for their integration as transparent electrodes in flexible optoelectronics. In situ X-ray diffraction measurements were used to study the crystallographic evolution of Ag-specific Bragg peaks during thermal ramping, revealing differences in thermal and structural transitions between bare and SnO2-coated AgNW networks.
Article
Chemistry, Multidisciplinary
Nathalia Cancino-Fuentes, Arnau Manasanch, Joana Covelo, Alex Suarez-Perez, Enrique Fernandez, Stratis Matsoukis, Christoph Guger, Xavi Illa, Anton Guimera-Brunet, Maria V. Sanchez-Vives
Summary: This study provides a comprehensive characterization of graphene-based solution-gated field-effect transistors (gSGFETs) for brain recordings, highlighting their potential clinical applications.
Article
Chemistry, Multidisciplinary
Sikandar Aftab, Hailiang Liu, Dhanasekaran Vikraman, Sajjad Hussain, Jungwon Kang, Abdullah A. Al-Kahtani
Summary: This study examines the effects of hybrid nanoparticles made of NiO@rGO and NiO@CNT on the active layers of polymer solar cells and X-ray photodetectors. The findings show that these hybrid nanoparticles can enhance the charge carrier capacities and exciton dissociation properties of the active layers. Among the tested configurations, the NiO@CNT device demonstrates superior performance in converting sunlight into electricity, and achieves the best sensitivity for X-ray detection.
Article
Chemistry, Multidisciplinary
Hyo Jung Shin, Seung Gyu Choi, Fengrui Qu, Min-Hee Yi, Choong-Hyun Lee, Sang Ryong Kim, Hyeong-Geug Kim, Jaewon Beom, Yoonyoung Yi, Do Kyung Kim, Eun-Hye Joe, Hee-Jung Song, Yonghyun Kim, Dong Woon Kim
Summary: This study investigates the role of SOX9 in reactive astrocytes following ischemic brain damage using a PLGA nanoparticle plasmid delivery system. The results demonstrate that PLGA nanoparticles can reduce ischemia-induced neurological deficits and infarct volume, providing a potential opportunity for stroke treatment.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Chemistry, Multidisciplinary
Sina Sadeghi, Fazel Bateni, Taekhoon Kim, Dae Yong Son, Jeffrey A. Bennett, Negin Orouji, Venkat S. Punati, Christine Stark, Teagan D. Cerra, Rami Awad, Fernando Delgado-Licona, Jinge Xu, Nikolai Mukhin, Hannah Dickerson, Kristofer G. Reyes, Milad Abolhasani
Summary: In this study, an autonomous approach for the development of lead-free metal halide perovskite nanocrystals is presented, which integrates a modular microfluidic platform with machine learning-assisted synthesis modeling. This approach enables rapid and optimized synthesis of copper-based lead-free nanocrystals.
Article
Chemistry, Multidisciplinary
Zahir Abbas, Nissar Hussain, Surender Kumar, Shaikh M. Mobin
Summary: The rational construction of free-standing and flexible electrodes for electrochemical energy storage devices is an emerging research focus. In this study, a redox-active metal-organic framework (MOF) was prepared on carbon nanofibers using an in situ approach, resulting in a flexible electrode with high redox-active behavior and unique properties such as high flexibility and lightweight. The prepared electrode showed excellent cyclic retention and rate capability in supercapacitor applications. Additionally, it could be used as a freestanding electrode in flexible devices at different bending angles.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu, Yingfeng Tu
Summary: Photodynamic therapy (PDT) is a promising local treatment modality in cancer therapy, but its therapeutic efficacy is restricted by ineffective delivery of photosensitizers and tumor hypoxia. In this study, a phototactic Chlorella-based near-infrared (NIR) driven green affording-oxygen microrobot system was developed for enhanced PDT. The system exhibited desirable phototaxis and continuous oxygen generation, leading to the inhibition of tumor growth in mice. This study demonstrates the potential of using a light-driven green affording-oxygen microrobot to enhance photodynamic therapy.
Article
Chemistry, Multidisciplinary
Yujin Li, Jing Xu, Xinqi Luo, Futing Wang, Zhong Dong, Ke-Jing Huang, Chengjie Hu, Mengyi Hou, Ren Cai
Summary: In this study, hollow heterostructured materials were constructed using an innovative template-engaged method as cathodes for zinc-ion batteries. The materials exhibited fast Zn2+ transport channels, improved electrical conductivity, and controlled volume expansion during cycling. The designed structure allowed for an admirable reversible capacity and high coulombic efficiency.
Article
Chemistry, Multidisciplinary
Paritosh Mahato, Shashi Shekhar, Rahul Yadav, Saptarshi Mukherjee
Summary: This study comprehensively elucidates the role of the core and electrostatic surface of metal nanoclusters in catalytic reduction reactions. The electrostatic surface dramatically modulates the reactivity of metal nanoclusters.
Article
Chemistry, Multidisciplinary
Pei Liu, Mengdi Liang, Zhengwei Liu, Haiyu Long, Han Cheng, Jiahe Su, Zhongbiao Tan, Xuewen He, Min Sun, Xiangqian Li, Shuai He
Summary: This study demonstrates a simple and environmentally-friendly method for the synthesis of zinc oxide nanozymes (ZnO NZs) using wasted hop extract (WHE). The WHE-ZnO NZs exhibit exceptional peroxidase-like activity and serve as effective catalysts for the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). In addition, a straightforward colorimetric technique for detecting both H2O2 and glucose was developed using the WHE-ZnO NZs as peroxidase-like catalysts.
Article
Chemistry, Multidisciplinary
Hyunkyu Oh, Young Jun Lee, Eun Ji Kim, Jinseok Park, Hee-Eun Kim, Hyunsoo Lee, Hyunjoo Lee, Bumjoon J. Kim
Summary: Mesoporous carbon particles have unique structural properties that make them suitable as support materials for catalytic applications. This study investigates the impact of channel nanostructures on the catalytic activity of porous carbon particles (PCPs) by fabricating PCPs with controlled channel exposure on the carbon surface. The results show that PCPs with highly open channel nanostructures exhibit significantly higher catalytic activity compared to those with closed channel nanostructures.
Article
Chemistry, Multidisciplinary
Yunjie Lu, Zhaohui Li, Zewei Li, Shihao Zhou, Ning Zhang, Jianming Zhang, Lu Zong
Summary: A tough, long-lasting adhesive and highly conductive nanocomposite hydrogel (PACPH) was fabricated via the synergy of interfacial entanglement and adhesion group densification. PACPH possesses excellent mechanical properties, interfacial adhesion strength, and conductivity, making it a promising material for long-term monitoring of human activities and electrocardiogram signals.
Article
Chemistry, Multidisciplinary
Zichao Wei, Audrey Vandergriff, Chung-Hao Liu, Maham Liaqat, Mu-Ping Nieh, Yu Lei, Jie He
Summary: We have developed a simple method to prepare polymer-grafted plasmonic metal nanoparticles with pH-responsive surface-enhanced Raman scattering. By using pH-responsive polymers as ligands, the aggregation of nanoparticles can be controlled, leading to enhanced SERS. The pH-responsive polymer-grafted nanoparticles show high reproducibility and sensitivity in solution, providing a novel approach for SERS without the need for sample pre-concentration.
Article
Chemistry, Multidisciplinary
Melis Ozge Alas Colak, Ahmet Gungor, Merve Buldu Akturk, Emre Erdem, Rukan Genc
Summary: This research investigates the effect of functionalizing carbon dots with hydroxyl polymers on their performance as electrode materials in a supercapacitor. The results show that the functionalized carbon dots exhibit excellent electrochemical performance and improved stability.
