Mitochondria-acting hexokinase II peptides carried by short-length carbon nanotubes with increased cellular uptake, endosomal evasion, and enhanced bioactivity against cancer cells

Ratiometric delivery of cisplatin and doxorubicin using tumour-targeting carbon-nanotubes entrapping platinum(iv) prodrugs

(2014) Chee Fei Chin et al.   Chemical Science

Carbon nanotubes for delivery of small molecule drugs

(2013) Bin Sheng Wong et al.   ADVANCED DRUG DELIVERY REVIEWS

Enhanced cytotoxicity to cancer cells by mitochondria-targeting MWCNTs containing platinum(IV) prodrug of cisplatin

(2013) Sia Lee Yoong et al.   BIOMATERIALS

Liberation of drugs from multi-wall carbon nanotube carriers

(2013) Sławomir Boncel et al.   JOURNAL OF CONTROLLED RELEASE

Peptide-based carbon nanotubes for mitochondrial targeting

(2013) Alessia Battigelli et al.   Nanoscale

Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma

(2013) L Wei et al.   Cell Death & Disease

Single-Walled Carbon Nanotubes Deliver Peptide Antigen into Dendritic Cells and Enhance IgG Responses to Tumor-Associated Antigens

(2011) Carlos H. Villa et al.   ACS Nano

Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts

(2011) Sandra Varum et al.   PLoS One

Imaging and drug delivery using theranostic nanoparticles

(2010) Siti M. Janib et al.   ADVANCED DRUG DELIVERY REVIEWS

Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism

(2010) Nataly Shulga et al.   CELL CYCLE

3-Bromopyruvate: A New Targeted Antiglycolytic Agent and a Promise for Cancer Therapy

(2010) S. Ganapathy-Kanniappan et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

A Soluble Form of the Pilus Protein FimA Targets the VDAC-Hexokinase Complex at Mitochondria to Suppress Host Cell Apoptosis

(2010) Sunil K. Sukumaran et al.   MOLECULAR CELL

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Covalently Combining Carbon Nanotubes with Anticancer Agent: Preparation and Antitumor Activity

(2009) Wei Wu et al.   ACS Nano

Enhanced anticancer activity of multi-walled carbon nanotube–methotrexate conjugates using cleavable linkers

(2009) Cristian Samorì et al.   CHEMICAL COMMUNICATIONS

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth

(2009) Neelesh R. Soman et al.   JOURNAL OF CLINICAL INVESTIGATION

Baxβ: A Constitutively Active Human Bax Isoform that Is under Tight Regulatory Control by the Proteasomal Degradation Mechanism

(2009) Nai Yang Fu et al.   MOLECULAR CELL

Endosomal Leakage and Nuclear Translocation of Multiwalled Carbon Nanotubes: Developing a Model for Cell Uptake

(2009) Qingxin Mu et al.   NANO LETTERS

Promises, facts and challenges for carbon nanotubes in imaging and therapeutics

(2009) K. Kostarelos et al.   Nature Nanotechnology

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Regulation of hexokinase binding to VDAC

(2008) John G. Pastorino et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

The long and short of carbon nanotube toxicity

(2008) Kostas Kostarelos   NATURE BIOTECHNOLOGY

Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels

(2008) Federica Chiara et al.   PLoS One

Functionalized Carbon Nanotubes in Drug Design and Discovery

(2007) Maurizio Prato et al.   ACCOUNTS OF CHEMICAL RESEARCH