4.7 Article

Advances in pediatric asthma in 2012: Moving toward asthma prevention

Journal

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Volume 131, Issue 1, Pages 36-46

Publisher

MOSBY-ELSEVIER
DOI: 10.1016/j.jaci.2012.11.009

Keywords

Airway remodeling; asthma; asthma control; asthma exacerbations; asthma impairment; asthma risk; asthma severity; early intervention in asthma; biomarkers; environment; genetics; inhaled corticosteroids; leukotriene receptor antagonists; long-acting beta-adrenergic agonists; omalizumab; personalized medicine; severe asthma; therapeutics; tiotropium

Funding

  1. Public Health Services research grants [HL-64288, HL-51834, AI-90052, HL-75416, HL-87811, ES-18181, HL-98075]
  2. Caring for Colorado Foundation
  3. Denver Post Charities
  4. McCormick Foundation
  5. Colorado Cancer
  6. Cardiovascular
  7. Pulmonary Disease Program
  8. Colorado CTSA
  9. NCRR/NIH [UL1 RR025780]
  10. NIH/NCATS [UL1 TR000154]

Ask authors/readers for more resources

Last year's Advances in pediatric asthma: moving forward'' concluded the following: Now is also the time to utilize information recorded in electronic medical records to develop innovative disease management plans that will track asthma over time and enable timely decisions on interventions in order to maintain control that can lead to disease remission and prevention.'' This year's summary will focus on recent advances in pediatric asthma on modifying disease activity, preventing asthma exacerbations, managing severe asthma, and risk factors for predicting and managing early asthma, as indicated in Journal of Allergy and Clinical Immunology publications in 2012. Recent reports continue to shed light on methods to improve asthma management through steps to assess disease activity, tools to standardize outcome measures in asthma, genetic markers that predict risk for asthma and appropriate treatment, and interventions that alter the early presentation of asthma to prevent progression. We are well on our way to creating a pathway around wellness in asthma care and also to use new tools to predict the risk for asthma and take steps to not only prevent asthma exacerbations but also to prevent the early manifestations of the disease and thus prevent its evolution to severe asthma. (J Allergy Clin Immunol 2013;131:36-46.)

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