Article
Allergy
Tai Ren, Jiawen Chen, Yongfu Yu, Hua He, Jun Zhang, Fei Li, Katrine Svendsen, Carsten Obel, Hui Wang, Jiong Li
Summary: This study found that women with a history of asthma, atopic dermatitis, and allergic rhinitis before conception had a 37% increased risk of peripartum mental disorders. Women who had more frequent or recent hospital contacts for atopic diseases had higher risks. Specific associations were observed between asthma and neurotic, stress-related and somatoform disorders, and between atopic dermatitis and substance abuse.
CLINICAL AND TRANSLATIONAL ALLERGY
(2021)
Article
Environmental Sciences
Juan Wang, Christer Janson, Andrei Malinovschi, Mathias Holm, Karl A. Franklin, Lars Modig, Ane Johannessen, Vivi Schluenssen, Thorarinn Gislason, Nils Oskar Jogi, Dan Norback
Summary: This study examined the relationship between home environment exposures and asthma, allergic rhinitis, and atopic dermatitis among offspring of participants in the Respiratory Health in Northern Europe (RHINE) study. The results showed that dampness/mold at home and living in new buildings were associated with asthma occurrence.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Medicine, General & Internal
Yu-Jih Su, Sheng-Dean Luo, Chung-Yuan Hsu, Ho-Chang Kuo
Summary: This study compared gut microbiota differences between patients with eczema, hives, and allergic rhinitis, revealing significant differences in gut flora between skin allergy and nose allergy patients, indicating the existence of gut-skin and gut-nose axes. Certain Bacteroidales species may be a clinical link between gut flora and skin allergies.
Review
Allergy
Andrew W. Liu, Jacob E. Gillis, Tina L. Sumpter, Daniel H. Kaplan
Summary: The skin is populated by various immune cells and sensory neurons, and the interaction between the nervous and immune systems plays a crucial role in inflammatory skin diseases. Neurotransmitters secreted by nerve terminals mediate immune cell function, while immune factors derived from immune cells interact with neurons to induce itching. This review explores the effector functions of neurons on skin immune cells in mouse models of atopic and contact dermatitis, and discusses the contribution of specific neuronal subsets and immune factors to itch induction and inflammation. The findings also shed light on treatment strategies and the relationship between scratching and dermatitis.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Medicine, General & Internal
Hyo Geun Choi, Il Gyu Kong
Summary: The study found that the incidence of asthma and allergic rhinitis among Korean adolescents decreased from 2019 to 2020, while there was no change in the incidence of atopic dermatitis. Subgroup analyses showed consistent results.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Allergy
Birgit Pfaller, Sarah Bendien, Agnes Ditisheim, Thomas Eiwegger
Summary: Managing allergic diseases during pregnancy presents challenges and potential risks for mother and child, especially with limited safety data on anti-allergic drugs during pregnancy.
Review
Biochemistry & Molecular Biology
Tobias Weihrauch, Maren M. Limberg, Natalie Gray, Martin Schmelz, Ulrike Raap
Summary: Allergic diseases can cause various symptoms such as itching, coughing, sneezing, and watery eyes, leading to severe physiological and psychological impairments. The mechanisms of these conditions are still not fully understood, but recent studies have shown the high relevance of neurotrophins in allergic inflammation. Neurotrophins induce cytokine release, facilitate interactions between immune cells and neurons, and show different expression levels in health and disease. In this review, the role of neurotrophins in atopic disorders like atopic dermatitis, allergic asthma, and allergic rhinitis is discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Allergy
Ju Hee Han, Hyun Ji Lee, Hwa Jung Yook, Kyungdo Han, Ji Hyun Lee, Young Min Park
Summary: This study investigated the association between atopic disorders and migraine in the Korean population. The results showed that patients with atopic dermatitis, asthma, and allergic rhinitis had an increased risk of migraine compared to the control group. Furthermore, the risk of migraine was higher in patients with multiple atopic disorders.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2023)
Article
Allergy
Ann-Marie Malby Schoos, Bo Lund Chawes, Klaus Bonnelykke, Jakob Stokholm, Morten Arendt Rasmussen, Hans Bisgaard
Summary: Early-onset and severe atopic dermatitis is associated with aeroallergen sensitization and allergic rhinitis in children, while late-onset atopic dermatitis does not show this association.
Review
Immunology
Mohammad-Hossein Shams, Reza Jafari, Nahid Eskandari, Mohsen Masjedi, Farnaz Kheirandish, Mazdak Ganjalikhani Hakemi, Ramin Ghasemi, Ali-Mohammad Varzi, Seyyed-Mohsen Sohrabi, Peyman Amanolahi Baharvand, Mozhgan Safari
Summary: Allergic diseases have significantly increased globally in recent decades, influenced by genetic factors, industrialization, improved hygiene, and climate change. Changes in lifestyle and diet habits also play a key role in the prevalence of allergic diseases.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Maya Berlin, Hadar Flor-Hirsch, Elkana Kohn, Anna Brik, Rimona Keidar, Ayelet Livne, Ronella Marom, Amit Ovental, Dror Mandel, Ronit Lubetzky, Pam Factor-Litvak, Josef Tovbin, Moshe Betser, Miki Moskovich, Ariela Hazan, Malka Britzi, Itai Gueta, Matitiahu Berkovitch, Ilan Matok, Uri Hamiel
Summary: The study aimed to investigate the association between maternal PCBs levels and atopic reactions in their offspring. The findings showed no significant association between exposure to PCBs and asthma, allergic rhinitis, or atopic dermatitis in children. More multi-participant studies with longer follow-up into later pediatric age are needed to further explore these relationships.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Pier Giorgio Puzzovio, Francesca Levi-Schaffer
Summary: The understanding of the pathologic mechanisms of asthma and atopic dermatitis has improved in recent years. However, the high heterogeneity of both diseases complicates diagnosis and treatment, with current strategies mainly focusing on symptom control rather than full healing. There is a need for more personalized approaches to improve diagnosis and treatment efficacy.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Pediatrics
Gheorghita Jugulete, Monica Luminos, Carmen Pavelescu, Madalina Maria Merisescu
Summary: COVID-19 has a milder impact on children compared to adults, but the emergence of new SARS-CoV-2 variants has affected treatment options for both adults and children, particularly those with allergies. This study evaluates the efficacy and tolerability of Remdesivir (RDV) in treating pediatric patients with COVID-19-associated allergies and investigates its impact on hospitalization duration. The findings suggest that RDV reduces the duration and severity of COVID-19 in children with allergies, leading to shorter hospital stays.
Article
Health Care Sciences & Services
Shung-Jie Chang, Ho-Chang Kuo, Wen-Jiun Chou, Ching-Shu Tsai, Sheng-Yu Lee, Liang-Jen Wang
Summary: This study examines the relationship between cytokine levels, neuropsychological function, and behavioral manifestations in patients with attention deficit hyperactivity disorder (ADHD) and atopic diseases. The study finds that behavioral symptoms and attention scores are significantly different between individuals with and without ADHD, regardless of atopic diseases. However, plasma levels of certain cytokines are negatively correlated with inattention symptoms.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Allergy
Lucy E. Bradshaw, Laura A. Wyatt, Sara J. Brown, Rachel H. Haines, Alan A. Montgomery, Michael R. Perkin, Sandra Lawton, Tracey H. Sach, Joanne R. Chalmers, Matthew J. Ridd, Carsten Flohr, Joanne Brooks, Richard Swinden, Eleanor J. Mitchell, Stella Tarr, Nicola Jay, Kim S. Thomas, Hilary Allen, Michael J. Cork, Maeve M. Kelleher, Eric L. Simpson, Stella T. Lartey, Susan Davies-Jones, Robert J. Boyle, Hywel C. Williams
Summary: The study found that daily emollient application during the first year of life does not prevent atopic dermatitis, food allergy, asthma, or hay fever. The difference in incidence rates of atopic dermatitis, food allergy, asthma, and hay fever between the emollient group and the control group was relatively small.
Article
Public, Environmental & Occupational Health
Brian A. Lynch, Amenah Agunwamba, Patrick M. Wilson, Seema Kumar, Robert M. Jacobson, Sean Phelan, Valeria Cristiani, Chun Fan, Lila J. Finney Rutten
PREVENTIVE MEDICINE
(2016)
Article
Public, Environmental & Occupational Health
Jennifer L. St Sauver, Lila J. Finney Rutten, Jon O. Ebbert, Debra J. Jacobson, Michaela E. McGree, Robert M. Jacobson
PREVENTIVE MEDICINE
(2016)
Review
Immunology
Iana H. Haralambieva, Inna G. Ovsyannikova, V. Shane Pankratz, Richard B. Kennedy, Robert M. Jacobson, Gregory A. Poland
EXPERT REVIEW OF VACCINES
(2013)
Article
Immunology
Inna G. Ovsyannikova, V. Shane Pankratz, Robert A. Vierkant, Nicholas M. Pajewski, Conrad P. Quinn, Richard A. Kaslow, Robert M. Jacobson, Gregory A. Poland
INFECTION AND IMMUNITY
(2013)
Article
Mathematical & Computational Biology
Yi Pan, Charles E. Rose, Michael Haber, Yan Ma, Josep L. Carrasco, Brock Stewart, Wendy A. Keitel, Harry Keyserling, Robert M. Jacobson, Gregory Poland, Michael M. McNeil
INTERNATIONAL JOURNAL OF BIOSTATISTICS
(2013)
Article
Multidisciplinary Sciences
Iana H. Haralambieva, Ann L. Oberg, Inna G. Ovsyannikova, Richard B. Kennedy, Diane E. Grill, Sumit Middha, Brian M. Bot, Vivian W. Wang, David I. Smith, Robert M. Jacobson, Gregory A. Poland
Review
Immunology
Gregory A. Poland, Richard B. Kennedy, Brett A. McKinney, Inna G. Ovsyannikova, Nathaniel D. Lambert, Robert M. Jacobson, Ann L. Oberg
SEMINARS IN IMMUNOLOGY
(2013)
Article
Immunology
Jennifer G. Wright, Brian D. Plikaytis, Charles E. Rose, Scott D. Parker, Janiine Babcock, Wendy Keitel, Hana El Sahly, Gregory A. Poland, Robert M. Jacobson, Harry L. Keyserling, Vera A. Semenova, Han Li, Jarad Schiffer, Hanan Dababneh, Sandra K. Martin, Stacey W. Martin, Nina Marano, Nancy E. Messonnier, Conrad P. Quinn
Article
Primary Health Care
Apurvi R. Patel, John Zietlow, Robert M. Jacobson, Gregory A. Poland, Young J. Juhn
PRIMARY CARE RESPIRATORY JOURNAL
(2013)
Editorial Material
Pediatrics
Su-Ting T. Li, Melissa Klein, Katherine A. Poehling, Robert M. Jacobson
ACADEMIC PEDIATRICS
(2019)
Review
Medicine, General & Internal
Robert M. Jacobson
MAYO CLINIC PROCEEDINGS
(2020)
Article
Biotechnology & Applied Microbiology
Robert M. Jacobson, Jennifer L. St Sauver, Joan M. Griffin, Kathy L. MacLaughlin, Lila J. Finney Rutten
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2020)
Review
Medicine, General & Internal
Robert M. Jacobson
MAYO CLINIC PROCEEDINGS
(2020)
Article
Biotechnology & Applied Microbiology
Alexandria C. Caldwell, Christi A. Madden, David M. Thompson, M. Connor Garbe, James R. Roberts, Robert M. Jacobson, Paul M. Darden
Summary: The study found that provider recommendation has a significant impact on adolescent vaccine coverage, particularly for the HPV vaccine. Vaccine coverage was generally higher among those who received a provider recommendation compared to those who did not.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Medicine, General & Internal
Lila J. Finney Rutten, Xuan Zhu, Aaron L. Leppin, Jennifer L. Ridgeway, Melanie D. Swift, Joan M. Griffin, Jennifer L. St Sauver, Abinash Virk, Robert M. Jacobson
Summary: The success of COVID-19 vaccination programs relies on scientific safety data, high acceptance rates, and population coverage. However, vaccine hesitancy and complacency about vaccination may undermine the success of these programs. Multilevel, evidence-based strategies are needed to address behavior change and vaccine hesitancy.
MAYO CLINIC PROCEEDINGS
(2021)