Graphene-based nanomaterials: biological and medical applications and toxicity

An ultra-sensitive acetylcholinesterase biosensor based on reduced graphene oxide-Au nanoparticles-β-cyclodextrin/Prussian blue-chitosan nanocomposites for organophosphorus pesticides detection

(2015) Haiyan Zhao et al.   BIOSENSORS & BIOELECTRONICS

Proximity-Induced Ferromagnetism in Graphene Revealed by the Anomalous Hall Effect

(2015) Zhiyong Wang et al.   PHYSICAL REVIEW LETTERS

Application of paramagnetic graphene quantum dots as a platform for simultaneous dual-modality bioimaging and tumor-targeted drug delivery

(2015) Chun-Lin Huang et al.   Journal of Materials Chemistry B

Self-Healing Reduced Graphene Oxide Films by Supersonic Kinetic Spraying

(2014) Do-Yeon Kim et al.   ADVANCED FUNCTIONAL MATERIALS

Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene

(2014) Tianyue Jiang et al.   ADVANCED MATERIALS

Graphene chemical vapor deposition at very low pressure: The impact of substrate surface self-diffusion in domain shape

(2014) T. H. R. Cunha et al.   APPLIED PHYSICS LETTERS

Simulation and analysis of cellular internalization pathways and membrane perturbation for graphene nanosheets

(2014) Jian Mao et al.   BIOMATERIALS

Gadolinium-functionalized nanographene oxide for combined drug and microRNA delivery and magnetic resonance imaging

(2014) Hung-Wei Yang et al.   BIOMATERIALS

Graphene meets biology

(2014) Ning Li et al.   CHINESE SCIENCE BULLETIN

Current approaches to enhance CNS delivery of drugs across the brain barriers

(2014) Cui-Tao Lu et al.   International Journal of Nanomedicine

Scale/Topography of Substrates Surface Resembling Extracellular Matrix for Tissue Engineering

(2014) Rodrigo R. Resende et al.   Journal of Biomedical Nanotechnology

Biological Applications of Gold Nanoparticles

(2014) Monic Shah et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Observation of Strain-Free Rolled-Up CVD Graphene Single Layers: Toward Unstrained Heterostructures

(2014) Ingrid D. Barcelos et al.   NANO LETTERS

Pure thiophene–sulfur doped reduced graphene oxide: synthesis, structure, and electrical properties

(2014) Zegao Wang et al.   Nanoscale

Technological Developments and Future Perspectives on Graphene-Based Metamaterials

(2014) Tobias A. Mattei et al.   NEUROSURGERY

Systemic Administration of Polymer-Coated Nano-Graphene to Deliver Drugs to Glioblastoma

(2014) Thomas L. Moore et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Gene delivery to Nile tilapia spermatogonial stem cells using carboxi-functionalized multiwall carbon nanotubes

(2014) F. M. P. Tonelli et al.   RSC Advances

Fabrication and characterization of flexible silk fibroin films reinforced with graphene oxide for biomedical applications

(2014) Lu Wang et al.   RSC Advances

Direct fabrication of graphene on SiO2 enabled by thin film stress engineering

(2014) Daniel Q. McNerny et al.   Scientific Reports

Fabrication of Graphene-isolated-Au-nanocrystal Nanostructures for Multimodal Cell Imaging and Photothermal-enhanced Chemotherapy

(2014) Xia Bian et al.   Scientific Reports

Photosensitizer Loaded Nano-Graphene for Multimodality Imaging Guided Tumor Photodynamic Therapy

(2014) Pengfei Rong et al.   Theranostics

Transferrin Modified Graphene Oxide for Glioma-Targeted Drug Delivery: In Vitro and in Vivo Evaluations

(2013) Guodong Liu et al.   ACS Applied Materials & Interfaces

Encapsulating Gold Nanoparticles or Nanorods in Graphene Oxide Shells as a Novel Gene Vector

(2013) Cheng Xu et al.   ACS Applied Materials & Interfaces

In Vivo Biodistribution and Toxicology of Carboxylated Graphene Quantum Dots

(2013) Md Nurunnabi et al.   ACS Nano

Quantitative and Multiplexed MicroRNA Sensing in Living Cells Based on Peptide Nucleic Acid and Nano Graphene Oxide (PANGO)

(2013) Soo-Ryoon Ryoo et al.   ACS Nano

Graphene-Based Anticancer Nanosystem and Its Biosafety Evaluation Using a Zebrafish Model

(2013) Chen-Wei Liu et al.   BIOMACROMOLECULES

In vivo biodistribution and toxicology of functionalized nano-graphene oxide in mice after oral and intraperitoneal administration

(2013) Kai Yang et al.   BIOMATERIALS

MicroRNAs as novel biological targets for detection and regulation

(2013) Jinbo Li et al.   CHEMICAL SOCIETY REVIEWS

Carbon Nanotubes

(2013) P.A. Martins-Júnior et al.   JOURNAL OF DENTAL RESEARCH

Microbial oxidation of dispersed graphite by nitrifying bacteria 2011.2

(2013) Chunlin Zhu et al.   Nanoscale

Flexible electrostatic nanogenerator using graphene oxide film

(2013) He Tian et al.   Nanoscale

Multifunctionality and control of the crumpling and unfolding of large-area graphene

(2013) Jianfeng Zang et al.   NATURE MATERIALS

Graphene mechanical oscillators with tunable frequency

(2013) Changyao Chen et al.   Nature Nanotechnology

Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets

(2013) Yusong Tu et al.   Nature Nanotechnology

Internalization and cytotoxicity of graphene oxide and carboxyl graphene nanoplatelets in the human hepatocellular carcinoma cell line Hep G2

(2013) Tobias Lammel et al.   Particle and Fibre Toxicology

Atomic surface structure of graphene and its buffer layer on SiC(0001): A chemical-specific photoelectron diffraction approach

(2013) L. H. de Lima et al.   PHYSICAL REVIEW B

The Role of Surface Oxygen in the Growth of Large Single-Crystal Graphene on Copper

(2013) Y. Hao et al.   SCIENCE

Polyethylene Glycol and Polyethylenimine Dual-Functionalized Nano-Graphene Oxide for Photothermally Enhanced Gene Delivery

(2013) Liangzhu Feng et al.   Small

Photothermally Controlled Gene Delivery by Reduced Graphene Oxide-Polyethylenimine Nanocomposite

(2013) Hyunwoo Kim et al.   Small

Biodistribution and pulmonary toxicity of intratracheally instilled graphene oxide in mice

(2013) Bo Li et al.   NPG Asia Materials

High-Quality Reduced Graphene Oxide by a Dual-Function Chemical Reduction and Healing Process

(2013) Surajit Some et al.   Scientific Reports

Multifunctional chitosan magnetic-graphene (CMG) nanoparticles: a theranostic platform for tumor-targeted co-delivery of drugs, genes and MRI contrast agents

(2013) Chunyan Wang et al.   Journal of Materials Chemistry B

Synthesis of Graphene Films by Rapid Heating and Quenching at Ambient Pressures and Their Electrochemical Characterization

(2012) L. David et al.   ACS Applied Materials & Interfaces

Using Graphene Oxide High Near-Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease

(2012) Meng Li et al.   ADVANCED MATERIALS

New Horizons for Diagnostics and Therapeutic Applications of Graphene and Graphene Oxide

(2012) Lingyan Feng et al.   ADVANCED MATERIALS

Impedance Based Nanotoxicity Assessment of Graphene Nanomaterials at the Cellular and Tissue Level

(2012) Evangelia Hondroulis et al.   ANALYTICAL LETTERS

Can Graphene Oxide Cause Damage to Eyesight?

(2012) Lu Yan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nano-graphene in biomedicine: theranostic applications

(2012) Kai Yang et al.   CHEMICAL SOCIETY REVIEWS

Construction of a Graphene Oxide Based Noncovalent Multiple Nanosupramolecular Assembly as a Scaffold for Drug Delivery

(2012) Yang Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent advances in graphene family materials toxicity investigations

(2012) Agnieszka Maria Jastrzębska et al.   JOURNAL OF NANOPARTICLE RESEARCH

Effect of Carbon Nanomaterials on the Germination and Growth of Rice Plants

(2012) Remya Nair et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Preparation of Graphene Quantum Dots for Bioimaging Application

(2012) Liming Zhang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Evidence for Charge-Transfer-Induced Conformational Changes in Carbon Nanostructure–Protein Corona

(2012) R. Podila et al.   Journal of Physical Chemistry C

Restoring Basal Planes of Graphene Oxides for Highly Efficient Loading and Delivery of β-Lapachone

(2012) Xin Ting Zheng et al.   MOLECULAR PHARMACEUTICS

Ultra-small graphene oxide functionalized with polyethylenimine (PEI) for very efficient gene delivery in cell and zebrafish embryos

(2012) Xiang Zhou et al.   Nano Research

A functionalized graphene oxide-iron oxide nanocomposite for magnetically targeted drug delivery, photothermal therapy, and magnetic resonance imaging

(2012) Xinxing Ma et al.   Nano Research

Polymeric nanogels as vaccine delivery systems

(2012) Sílvia A. Ferreira et al.   Nanomedicine-Nanotechnology Biology and Medicine

Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C70 and C84O2 Fullerene Derivatives

(2012) Felipe F. Sperandio et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mechanical properties of graphene oxides

(2012) Lizhao Liu et al.   Nanoscale

Graphene: a versatile nanoplatform for biomedical applications

(2012) Yin Zhang et al.   Nanoscale

Toxicity of a polymer–graphene oxide composite against bacterial planktonic cells, biofilms, and mammalian cells

(2012) Isis E. Mejías Carpio et al.   Nanoscale

Engineered Redox-Responsive PEG Detachment Mechanism in PEGylated Nano-Graphene Oxide for Intracellular Drug Delivery

(2012) Huiyun Wen et al.   Small

Biomimetic superelastic graphene-based cellular monoliths

(2012) Ling Qiu et al.   Nature Communications

Graphene coatings for enhanced hemo-compatibility of nitinol stents

(2012) Ramakrishna Podila et al.   RSC Advances

Folic Acid-conjugated Graphene Oxide loaded with Photosensitizers for Targeting Photodynamic Therapy

(2012) Peng Huang et al.   Theranostics

Cytotoxicity of Graphene Oxide and Graphene in Human Erythrocytes and Skin Fibroblasts

(2011) Ken-Hsuan Liao et al.   ACS Applied Materials & Interfaces

Graphene Oxide: A Nonspecific Enhancer of Cellular Growth

(2011) Oscar N. Ruiz et al.   ACS Nano

Protein Corona-Mediated Mitigation of Cytotoxicity of Graphene Oxide

(2011) Wenbing Hu et al.   ACS Nano

Graphene for Controlled and Accelerated Osteogenic Differentiation of Human Mesenchymal Stem Cells

(2011) Tapas R. Nayak et al.   ACS Nano

Antibacterial Activity of Graphite, Graphite Oxide, Graphene Oxide, and Reduced Graphene Oxide: Membrane and Oxidative Stress

(2011) Shaobin Liu et al.   ACS Nano

Graphene-Based Nanoplatelets: A New Risk to the Respiratory System as a Consequence of Their Unusual Aerodynamic Properties

(2011) Anja Schinwald et al.   ACS Nano

Structure–process–property relationship of the polar graphene oxide-mediated cellular response and stimulated growth of osteoblasts on hybrid chitosan network structure nanocomposite scaffolds

(2011) D. Depan et al.   Acta Biomaterialia

Water-Soluble Poly(N-isopropylacrylamide)-Graphene Sheets Synthesized via Click Chemistry for Drug Delivery

(2011) Yongzheng Pan et al.   ADVANCED FUNCTIONAL MATERIALS

Enhanced Differentiation of Human Neural Stem Cells into Neurons on Graphene

(2011) Sung Young Park et al.   ADVANCED MATERIALS

Gold Nanoclusters and Graphene Nanocomposites for Drug Delivery and Imaging of Cancer Cells

(2011) Chensu Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Graphene Oxide–Polyethylenimine Nanoconstruct as a Gene Delivery Vector and Bioimaging Tool

(2011) Hyunwoo Kim et al.   BIOCONJUGATE CHEMISTRY

The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates

(2011) Ning Li et al.   BIOMATERIALS

A graphene-based platform for induced pluripotent stem cells culture and differentiation

(2011) G.-Y. Chen et al.   BIOMATERIALS

Multi-functional graphene as an in vitro and in vivo imaging probe

(2011) Ganesh Gollavelli et al.   BIOMATERIALS

Graphene phytotoxicity in the seedling stage of cabbage, tomato, red spinach, and lettuce

(2011) Parvin Begum et al.   CARBON

Strongly green-photoluminescent graphene quantum dots for bioimaging applications

(2011) Shoujun Zhu et al.   CHEMICAL COMMUNICATIONS

Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

(2011) Nanda Gopal Sahoo et al.   CHEMICAL COMMUNICATIONS

Biological Interactions of Graphene-Family Nanomaterials: An Interdisciplinary Review

(2011) Vanesa C. Sanchez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Two-Dimensional Nanocomposites Based on Chemically Modified Graphene

(2011) Dongqing Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Graphene Oxide Noncovalent Photosensitizer and Its Anticancer Activity In Vitro

(2011) Lin Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide

(2011) Malgorzata Wojtoniszak et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Functionalized Graphene Oxide as Nanocarrier for Loading and Delivery of Ellagic Acid

(2011) M. Kakran et al.   CURRENT MEDICINAL CHEMISTRY

What Makes a Natural Clay Antibacterial?

(2011) Lynda B. Williams et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Engineering of a novel pluronic F127/graphene nanohybrid for pH responsive drug delivery

(2011) Haiqing Hu et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Polyethylenimine-functionalized graphene oxide as an efficient gene delivery vector

(2011) Biao Chen et al.   JOURNAL OF MATERIALS CHEMISTRY

High strength graphene oxide/polyvinyl alcohol composite hydrogels

(2011) Lu Zhang et al.   JOURNAL OF MATERIALS CHEMISTRY

Electronic properties of graphene nanostructures

(2011) F Molitor et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

A graphene modified anode to improve the performance of microbial fuel cells

(2011) Yezhen Zhang et al.   JOURNAL OF POWER SOURCES

Ultrasmall Reduced Graphene Oxide with High Near-Infrared Absorbance for Photothermal Therapy

(2011) Joshua T. Robinson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlled release of drug from folate-decorated and graphene mediated drug delivery system: Synthesis, loading efficiency, and drug release response

(2011) D. Depan et al.   Materials Science & Engineering C-Materials for Biological Applications

Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

(2011) Matthew C. Duch et al.   NANO LETTERS

Microbial reduction of graphene oxide by Shewanella

(2011) Gongming Wang et al.   Nano Research

Graphene in biomedicine: opportunities and challenges

(2011) Liangzhu Feng et al.   Nanomedicine

Adsorption of double-stranded DNA to graphene oxide preventing enzymatic digestion

(2011) Haozhi Lei et al.   Nanoscale

Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

(2011) Abhilash Sasidharan et al.   Nanoscale

Properties of graphene inks stabilized by different functional groups

(2011) Di Wei et al.   NANOTECHNOLOGY

Chitosan-Functionalized Graphene Oxide as a Nanocarrier for Drug and Gene Delivery

(2011) Hongqian Bao et al.   Small

Cytotoxicity Evaluation of Oxidized Single-Walled Carbon Nanotubes and Graphene Oxide on Human Hepatoma HepG2 cells: An iTRAQ-Coupled 2D LC-MS/MS Proteome Analysis

(2011) Jifeng Yuan et al.   TOXICOLOGICAL SCIENCES

Graphene and graphene oxide: biofunctionalization and applications in biotechnology

(2011) Ying Wang et al.   TRENDS IN BIOTECHNOLOGY

Cytotoxicity Effects of Graphene and Single-Wall Carbon Nanotubes in Neural Phaeochromocytoma-Derived PC12 Cells

(2010) Yongbin Zhang et al.   ACS Nano

Behaviors of NIH-3T3 Fibroblasts on Graphene/Carbon Nanotubes: Proliferation, Focal Adhesion, and Gene Transfection Studies

(2010) Soo-Ryoon Ryoo et al.   ACS Nano

In Vivo Pharmacokinetics, Long-Term Biodistribution, and Toxicology of PEGylated Graphene in Mice

(2010) Kai Yang et al.   ACS Nano

Toxicity of Graphene and Graphene Oxide Nanowalls Against Bacteria

(2010) Omid Akhavan et al.   ACS Nano

Fabrication, Mechanical Properties, and Biocompatibility of Graphene-Reinforced Chitosan Composites

(2010) Hailong Fan et al.   BIOMACROMOLECULES

In vitro comparison of the photothermal anticancer activity of graphene nanoparticles and carbon nanotubes

(2010) Zoran M. Markovic et al.   BIOMATERIALS

Gold nanorod-based localized surface plasmon resonance biosensor for sensitive detection of hepatitis B virus in buffer, blood serum and plasma

(2010) Xiaohui Wang et al.   BIOSENSORS & BIOELECTRONICS

Using graphene to protect DNA from cleavage during cellular delivery

(2010) Chun-Hua Lu et al.   CHEMICAL COMMUNICATIONS

Nitrogen-doped graphene and its electrochemical applications

(2010) Yuyan Shao et al.   JOURNAL OF MATERIALS CHEMISTRY

Graphene Oxide Nanocolloids

(2010) Jiayan Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Label-Free Biosensors Based on Aptamer-Modified Graphene Field-Effect Transistors

(2010) Yasuhide Ohno et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interfacing Live Cells with Nanocarbon Substrates

(2010) Shuchi Agarwal et al.   LANGMUIR

Synthesis and Drug-Delivery Behavior of Chitosan-Functionalized Graphene Oxide Hybrid Nanosheets

(2010) Vijay Kumar Rana et al.   MACROMOLECULAR MATERIALS AND ENGINEERING

Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy

(2010) Kai Yang et al.   NANO LETTERS

Nanoscale Tunable Reduction of Graphene Oxide for Graphene Electronics

(2010) Z. Wei et al.   SCIENCE

Poly(ethylene glycol) conjugated nano-graphene oxide for photodynamic therapy

(2010) HaiQing Dong et al.   Science China-Chemistry

Graphene Oxide, Highly Reduced Graphene Oxide, and Graphene: Versatile Building Blocks for Carbon-Based Materials

(2010) Owen C. Compton et al.   Small

In vitro toxicity evaluation of graphene oxide on A549 cells

(2010) Yanli Chang et al.   TOXICOLOGY LETTERS

Cooperative Nanoparticles for Tumor Detection and Photothermally Triggered Drug Delivery

(2009) Ji-Ho Park et al.   ADVANCED MATERIALS

Reduction of graphene oxide vial-ascorbic acid

(2009) Jiali Zhang et al.   CHEMICAL COMMUNICATIONS

The chemistry of graphene oxide

(2009) Daniel R. Dreyer et al.   CHEMICAL SOCIETY REVIEWS

Superparamagnetic graphene oxide–Fe3O4 nanoparticles hybrid for controlled targeted drug carriers

(2009) Xiaoying Yang et al.   JOURNAL OF MATERIALS CHEMISTRY

Conjugation of 2-(1′-Hexyloxyethyl)-2-devinylpyropheophorbide-a (HPPH) to Carbohydrates Changes its Subcellular Distribution and Enhances Photodynamic Activity in Vivo†

(2009) Xiang Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nanostructured 3-D collagen/nanotube biocomposites for future bone regeneration scaffolds

(2009) Edelma E. da Silva et al.   Nano Research

Large-scale pattern growth of graphene films for stretchable transparent electrodes

(2009) Keun Soo Kim et al.   NATURE

Chemical methods for the production of graphenes

(2009) Sungjin Park et al.   Nature Nanotechnology

Gold Nanorods as Contrast Agents for Biological Imaging: Optical Properties, Surface Conjugation and Photothermal Effects

(2009) Ling Tong et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Functional Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Mixed Anticancer Drugs

(2009) Liming Zhang et al.   Small

High-Efficiency Loading and Controlled Release of Doxorubicin Hydrochloride on Graphene Oxide

(2008) Xiaoying Yang et al.   Journal of Physical Chemistry C

PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs

(2008) Zhuang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Graphene Oxide Dispersions in Organic Solvents

(2008) J. I. Paredes et al.   LANGMUIR

Synthesis of Water Soluble Graphene

(2008) Yongchao Si et al.   NANO LETTERS

Superior Thermal Conductivity of Single-Layer Graphene

(2008) Alexander A. Balandin et al.   NANO LETTERS

Large Area, Few-Layer Graphene Films on Arbitrary Substrates by Chemical Vapor Deposition

(2008) Alfonso Reina et al.   NANO LETTERS

Nano-graphene oxide for cellular imaging and drug delivery

(2008) Xiaoming Sun et al.   Nano Research

Carbon nanotubes as functional excipients for nanomedicines: I. pharmaceutical properties

(2008) Marianna Foldvari et al.   Nanomedicine-Nanotechnology Biology and Medicine

Carbon nanotubes as functional excipients for nanomedicines: II. Drug delivery and biocompatibility issues

(2008) Marianna Foldvari et al.   Nanomedicine-Nanotechnology Biology and Medicine

Processable aqueous dispersions of graphene nanosheets

(2008) Dan Li et al.   Nature Nanotechnology

Large-area ultrathin films of reduced graphene oxide as a transparent and flexible electronic material

(2008) Goki Eda et al.   Nature Nanotechnology

Functionalized graphene sheets for polymer nanocomposites

(2008) T. Ramanathan et al.   Nature Nanotechnology

Measurement of the Elastic Properties and Intrinsic Strength of Monolayer Graphene

(2008) C. Lee et al.   SCIENCE

Ultrahigh electron mobility in suspended graphene

(2008) K.I. Bolotin et al.   SOLID STATE COMMUNICATIONS