Article
Allergy
Azahara M. Garcia-Serna, Elena Martin-Orozco, Pedro Jimenez-Guerrero, Trinidad Hernandez-Caselles, Virginia Perez-Fernandez, Esther Cantero-Cano, Maria Munoz-Garcia, Maria Dolores Molina-Ruano, Encarna Rojo-Atenza, Luis Garcia-Marcos, Eva Morales
Summary: This study found that gestational exposure to traffic-related air pollutants may increase the detection rate of pro-inflammatory, Th2-related, and T regulatory cytokines in newborns, which may influence their immune system responses later in life.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Qi-Qing Ye, Shao-Min Kong, Xin Yin, Chang Gao, Min-Shan Lu, Rema Ramakrishnan, Cheng Guo, Wang Yao, Ji-Yuan Zeng, Ya-Shu Kuang, Jin-Hua Lu, Jian-Rong He, Xiu Qiu
Summary: This study aimed to investigate the associations between cord blood lipids and childhood adiposity, as well as to explore whether these associations vary across different birth weight categories. The results revealed that cord blood triglycerides were negatively associated with childhood adiposity, while high density lipoprotein levels were positively associated. Furthermore, the correlations between cord blood total cholesterol, low-density lipoprotein levels, and childhood adiposity indicators varied across different birth weight categories.
Article
Nutrition & Dietetics
Yiming Dai, Jiming Zhang, Xiaojuan Qi, Zheng Wang, Minglan Zheng, Ping Liu, Shuai Jiang, Jianqiu Guo, Chunhua Wu, Zhijun Zhou
Summary: The study shows that prenatal exposure to manganese is positively associated with ponderal index at birth and negatively associated with physical growth in early childhood, but not significant for children aged 6 and above.
Review
Immunology
Huaguo Tang, Yuanjie Gu, Lei Jiang, Gang Zheng, Zhuoer Pan, Xiugui Jiang
Summary: Spinal cord injury (SCI) is a devastating neurological condition worldwide. The immune response plays a crucial role in tissue regeneration and functional recovery from SCI. New biological technologies have allowed for more precise classification of the heterogeneity of immune components. This review focuses on the roles of various immune cells and chemicals in SCI and summarizes clinical trials of immunomodulatory therapies and promising therapeutic drugs.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Endocrinology & Metabolism
Dongjian Yang, Jingbo Qiu, An Qin, Lei Chen, Ya Yang, Zhen Huang, Jieyan Qian, Wei Zhu
Summary: This study found an association between birth season and gestational diabetes mellitus in East China, with pregnant women born in autumn showing higher postprandial blood glucose levels during pregnancy. The findings suggest that exposure to seasonal changes in early life may influence blood glucose metabolism during pregnancy.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Nutrition & Dietetics
Martina Barchitta, Roberta Magnano San Lio, Maria Clara La Rosa, Claudia La Mastra, Giuliana Favara, Giuliana Ferrante, Fabiola Galvani, Elisa Pappalardo, Carla Ettore, Giuseppe Ettore, Antonella Agodi, Andrea Maugeri
Summary: Limited evidence exists on the effects of maternal dietary patterns on birth weight, and most studies conducted so far did not adjust their findings for gestational age and sex, leading to potentially biased conclusions. In this study, a novel method was applied to derive dietary patterns among pregnant women and evaluate the associations with birth weight for gestational age. The findings suggest that adherence to an unhealthy dietary pattern is associated with an increased likelihood of having a large for gestational age newborn.
Article
Anesthesiology
Alexander J. Butwick, Can Liu, Nan Guo, Jason Bentley, Elliot K. Main, Jonathan A. Mayo, Gary M. Shaw, Olof Stephansson
Summary: This study examined the association between gestational age at delivery and postpartum hemorrhage in women from Sweden and California. The findings showed that the incidence of postpartum hemorrhage was highest for deliveries between 41 and 42 weeks' gestation in both regions, with higher odds compared to deliveries between 37 and 38 weeks.
Article
Nutrition & Dietetics
Shangzhi Xu, Weiming Wang, Qian Li, Li Huang, Xi Chen, Xu Zhang, Xiaoyi Wang, Weizhen Han, Xingwen Hu, Xuefeng Yang, Liping Hao, Guoping Xiong, Nianhong Yang
Summary: This study found that higher Hb concentrations in late pregnancy and less reduction in Hb during pregnancy were associated with an increased risk of SGA in women at low risk of iron deficiency.
Article
Environmental Sciences
Ram C. Siwakoti, Amber Cathey, Kelly K. Ferguson, Wei Hao, David E. Cantonwine, Bhramar Mukherjee, Thomas F. McElrath, John D. Meeker
Summary: This study found that prenatal exposure to PFAS may have an impact on pregnancy outcomes, including preterm birth and large-for-gestational age (LGA). However, the effects of PFAS on these outcomes depend on the fetal sex. Specifically, certain PFAS were associated with placental preterm birth, with stronger associations observed in male fetuses. For LGA, different PFAS had different effects in females and males.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Chaochen Ma, Miyuki Iwai-Shimada, Shoji F. Nakayama, Tomohiko Isobe, Yayoi Kobayashi, Nozomi Tatsuta, Yu Taniguchi, Makiko Sekiyama, Takehiro Michikawa, Shin Yamazaki, Michihiro Kamijima
Summary: Prenatal cadmium exposure was negatively associated with neurodevelopment in boys, in children whose mothers smoked, and in children born to mothers with gestational diabetes. Further studies in other populations are needed to confirm our findings.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Immunology
Archana Kulkarni-Munje, Nandini Malshe, Sonali Palkar, Aniket Amlekar, Sanjay Lalwani, Akhilesh Chandra Mishra, Vidya Arankalle
Summary: Research shows that preterm infants in India may have lower immune response to pentavalent vaccine and may require additional doses for robust immune protection.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Endocrinology & Metabolism
Wen-Juan Wang, Rong Huang, Tao Zheng, Qinwen Du, Meng-Nan Yang, Ya-Jie Xu, Xin Liu, Min-Yi Tao, Hua He, Fang Fang, Fei Li, Jian-Gao Fan, Jun Zhang, Laurent Briollais, Fengxiu Ouyang, Zhong-Cheng Luo
Summary: This study found that gestational diabetes mellitus (GDM) is associated with DNA methylation changes in placental genes, but these changes are not correlated with metabolic health biomarkers in cord blood. Eleven differentially methylated genes were identified to be relevant to fetal growth.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pediatrics
Yue Zhang, Chun-Yan Zhou, Xi-Rui Wang, Xian-Ting Jiao, Jun Zhang, Ying Tian, Luan-Luan Li, Chen Chen, Xiao-Dan Yu
Summary: This study aimed to examine the association between 25-hydroxyvitamin D levels during pregnancy and at birth with neurodevelopment at 24 months of age. The findings revealed that higher cord blood levels of 25-hydroxyvitamin D were positively correlated with cognitive, language, and motor development at 24 months of age. Sufficient vitamin D status during pregnancy may serve as a protective factor against suboptimal neurocognitive development at 24 months of age.
WORLD JOURNAL OF PEDIATRICS
(2023)
Article
Pediatrics
Ian Henderson, Siobhan Quenby
Summary: Gestational hypertension was weakly positively associated with childhood asthma, partly mediated by earlier delivery. Only a small proportion of early childhood asthma was attributable to gestational hypertensive disease in this representative UK-based birth cohort.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Cardiac & Cardiovascular Systems
Merida Rodriguez-Lopez, Alvaro Sepulveda-Martinez, Gabriel Bernardino, Francesca Crovetto, Carolina Pajuelo, Marta Sitges, Bart Bijnens, Eduard Gratacos, Fatima Crispi
Summary: This study assessed the differences in cardiometabolic health between adults born small for gestational age. The results showed that females born small for gestational age are more prone to cardiac dysfunction, while males are more likely to experience changes in electrocardiography, vascular health, and metabolism.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Nutrition & Dietetics
Peter J. Gergen, Stephen J. Teach, Herman E. Mitchell, Robert F. Freishtat, Agustin Calatroni, Elizabeth Matsui, Meyer Kattan, Gordon R. Bloomberg, Andrew H. Liu, Carolyn Kercsmar, George O'Connor, Jacqueline Pongracic, Yadira Rivera-Sanchez, Wayne J. Morgan, Christine A. Sorkness, Neil Binkley, William Busse
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2013)
Article
Critical Care Medicine
Katrina Steiling, Maarten van den Berge, Kahkeshan Hijazi, Roberta Florido, Joshua Campbell, Gang Liu, Ji Xiao, Xiaohui Zhang, Grant Duclos, Eduard Drizik, Huiqing Si, Catalina Perdomo, Charles Dumont, Harvey O. Coxson, Yuriy O. Alekseyev, Don Sin, Peter Pare, James C. Hogg, Annette McWilliams, Pieter S. Hiemstra, Peter J. Sterk, Wim Timens, Jeffrey T. Chang, Paola Sebastiani, George T. O'Connor, Andrea H. Bild, Dirkje S. Postma, Stephen Lam, Avrum Spira, Marc E. Lenburg
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2013)
Article
Critical Care Medicine
Mary B. Rice, Petter L. Ljungman, Elissa H. Wilker, Diane R. Gold, Joel D. Schwartz, Petros Koutrakis, George R. Washko, George T. O'Connor, Murray A. Mittleman
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2013)
Article
Allergy
Patricia F. Coogan, Jeffrey Yu, George T. O'Connor, Timothy A. Brown, Julie R. Palmer, Lynn Rosenberg
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
(2014)
Article
Oncology
Traci N. Bethea, Lynn Rosenberg, Marjory Charlot, George T. O'Connor, Lucile L. Adams-Campbell, Julie R. Palmer
CANCER CAUSES & CONTROL
(2013)
Article
Critical Care Medicine
Patricia F. Coogan, Jeffrey Yu, George T. O'Connor, Timothy A. Brown, Yvette C. Cozier, Julie R. Palmer, Lynn Rosenberg
Article
Medicine, Research & Experimental
Augusto A. Litonjua, Nancy E. Lange, Vincent J. Carey, Stacey Brown, Nancy Laranjo, Benjamin J. Harshfield, George T. O'Connor, Megan Sandel, Robert C. Strunk, Leonard B. Bacharier, Robert S. Zeiger, Michael Schatz, Bruce W. Hollis, Scott T. Weiss
CONTEMPORARY CLINICAL TRIALS
(2014)
Article
Genetics & Heredity
Nadia N. Hansel, Ingo Ruczinski, Nicholas Rafaels, Don D. Sin, Denise Daley, Alla Malinina, Lili Huang, Andrew Sandford, Tanda Murray, Yoonhee Kim, Candelaria Vergara, Susan R. Heckbert, Bruce M. Psaty, Guo Li, W. Mark Elliott, Farzian Aminuddin, Josee Dupuis, George T. O'Connor, Kimberly Doheny, Alan F. Scott, H. Marike Boezen, Dirkje S. Postma, Joanna Smolonska, Pieter Zanen, Firdaus A. Mohamed Hoesein, Harry J. de Koning, Ronald G. Crystal, Toshiko Tanaka, Luigi Ferrucci, Edwin Silverman, Emily Wan, Jorgen Vestbo, David A. Lomas, John Connett, Robert A. Wise, Enid R. Neptune, Rasika A. Mathias, Peter D. Pare, Terri H. Beaty, Kathleen C. Barnes
Article
Genetics & Heredity
David B. Kantor, Cameron D. Palmer, Taylor R. Young, Yan Meng, Zofia K. Gajdos, Helen Lyon, Alkes L. Price, Samuela Pollack, Stephanie J. London, Laura R. Loehr, Lewis J. Smith, Rajesh Kumar, David R. Jacobs, Marcy F. Petrini, George T. O'Connor, Wendy B. White, George Papanicolaou, Kristin M. Burkart, Susan R. Heckbert, R. Graham Barr, Joel N. Hirschhorn
Article
Allergy
Patricia F. Coogan, Lauren A. Wise, George T. O'Connor, Timothy A. Brown, Julie R. Palmer, Lynn Rosenberg
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2013)
Article
Allergy
Robert A. Wood, Alkis Togias, Jeremy Wildfire, Cynthia M. Visness, Elizabeth C. Matsui, Rebecca Gruchalla, Gurjit Hershey, Andrew H. Liu, George T. O'Connor, Jacqueline A. Pongracic, Edward Zoratti, Frederic Little, Mark Granada, Suzanne Kennedy, Stephen R. Durham, Mohamed H. Shamji, William W. Busse
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2014)
Article
Medicine, General & Internal
Gary M. Hunninghake, Hiroto Hatabu, Yuka Okajima, Wei Gao, Josee Dupuis, Jeanne C. Latourelle, Mizuki Nishino, Tetsuro Araki, Oscar E. Zazueta, Sila Kurugol, James C. Ross, Raul San Jose Estepar, Elissa Murphy, Mark P. Steele, James E. Loyd, Marvin I. Schwarz, Tasha E. Fingerlin, Ivan O. Rosas, George R. Washko, George T. O'Connor, David A. Schwartz
NEW ENGLAND JOURNAL OF MEDICINE
(2013)
Article
Clinical Neurology
Hassan A. Chami, Joao D. Fontes, Ramachandran S. Vasan, John F. Keaney, George T. O'Connor, Martin G. Larson, Emelia J. Benjamin, Daniel J. Gottlieb
Article
Allergy
Christine A. Sorkness, Jeremy J. Wildfire, Agustin Calatroni, Herman E. Mitchell, William W. Busse, George T. O'Connor, Jacqueline A. Pongracic, Kristie Ross, Michelle A. Gill, Meyer Kattan, Wayne J. Morgan, Stephen J. Teach, Peter J. Gergen, Andrew H. Liu, Stanley J. Szefler
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2013)
Article
Respiratory System
Andrew J. Synn, Chunyi Zhang, George R. Washko, Flabl San Jose Estepar, George T. O'Connor, Wenyuan Li, Murray A. Mittleman, Mary B. Rice
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2019)