Beyond passive immunization: toward a nanoparticle-based IL-17 vaccine as first in class of future immune treatments

Encephalitis related to a H1N1 vaccination: Case report and review of the literature

(2014) Isabelle Van Ussel et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials

(2014) Richard G. Langley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-17 Induces an Atypical M2-Like Macrophage Subpopulation That Regulates Intestinal Inflammation

(2014) Kenichiro Nishikawa et al.   PLoS One

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers

(2014) Jenny G.H. Low et al.   VACCINE

Protective Vaccination against Papillomavirus-Induced Skin Tumors under Immunocompetent and Immunosuppressive Conditions: A Preclinical Study Using a Natural Outbred Animal Model

(2014) Sabrina E. Vinzón et al.   PLoS Pathogens

Immunogenicity of Quadrivalent Human Papillomavirus Vaccine in Organ Transplant Recipients

(2013) D. Kumar et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Vaccine design: emerging concepts and renewed optimism

(2013) Sebastian K Grimm et al.   CURRENT OPINION IN BIOTECHNOLOGY

An ACT1 Mutation Selectively Abolishes Interleukin-17 Responses in Humans with Chronic Mucocutaneous Candidiasis

(2013) Bertrand Boisson et al.   IMMUNITY

T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies

(2013) Constanze Hess et al.   JOURNAL OF CLINICAL INVESTIGATION

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

(2013) F. Spensieri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of baculovirus expression system for generation of virus-like particles: Successes and challenges

(2013) Fuxiao Liu et al.   PROTEIN EXPRESSION AND PURIFICATION

Diacylglycerol Kinase   Limits B Cell Antigen Receptor-Dependent Activation of ERK Signaling to Inhibit Early Antibody Responses

(2013) M. L. Wheeler et al.   Science Signaling

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

Long-Lasting T Cell-Independent IgG Responses Require MyD88-Mediated Pathways and Are Maintained by High Levels of Virus Persistence

(2013) F. M. Raval et al.   mBio

Virus-induced humoral immunity: on how B cell responses are initiated

(2013) Franziska Zabel et al.   Current Opinion in Virology

Brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: a critical appraisal

(2012) Ph. I. Spuls et al.   BRITISH JOURNAL OF DERMATOLOGY

The early cellular signatures of protective immunity induced by live viral vaccination

(2012) Siegfried Kohler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis

(2012) Alain C. Tissot et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

Phenotype and function of protective, CD4-independent CD8 T cell memory

(2012) Lindsay E. Edwards et al.   IMMUNOLOGIC RESEARCH

An IL-17 peptide-based and virus-like particle vaccine enhances the bioactivity of IL-17in vitroandin vivo

(2012) Qingdong Guan et al.   Immunotherapy

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

IL-17 signaling in host defense against Candida albicans

(2011) Sarah L. Gaffen et al.   IMMUNOLOGIC RESEARCH

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Therapeutic vaccines for chronic diseases: successes and technical challenges

(2011) M. F. Bachmann et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

Bystander stimulation of activated CD4+T cells of unrelated specificity following a booster vaccination with tetanus toxoid

(2010) Gianfranco Di Genova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

(2010) John S. Cho et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

(2010) Kai Kisand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I IFN enhances follicular B cell contribution to the T cell–independent antibody response

(2010) Cristina L. Swanson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza

(2010) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Combined vaccination against IL-5 and eotaxin blocks eosinophilia in mice

(2010) Yu Zou et al.   VACCINE

A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice

(2010) Gunther Spohn et al.   Virology Journal

Alveolar Macrophages and Lung Dendritic Cells Sense RNA and Drive Mucosal IgA Responses

(2009) J. Bessa et al.   JOURNAL OF IMMUNOLOGY

Generation of Protective T Cell-Independent Antiviral Antibody Responses in SCID Mice Reconstituted with Follicular or Marginal Zone B Cells

(2009) H. M. Guay et al.   JOURNAL OF IMMUNOLOGY

Immunodrugs: Therapeutic VLP-Based Vaccines for Chronic Diseases

(2008) Gary T. Jennings et al.   Annual Review of Pharmacology and Toxicology

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis

(2008) Gunther Spohn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Evaluation of the Immune Response to a 2‐Dose Measles Vaccination Schedule Administered at 6 and 9 Months of Age to HIV‐Infected and HIV‐Uninfected Children in Malawi

(2008) Rita F. Helfand et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study

(2008) Alain C Tissot et al.   LANCET