Article
Polymer Science
Pornsawan Kum-onsa, Narong Chanlek, Jedsada Manyam, Prasit Thongbai, Viyada Harnchana, Nutthakritta Phromviyo, Prinya Chindaprasirt
Summary: A novel high-permittivity polymer nanocomposite system was fabricated in this study, consisting of gold nanoparticles and semiconducting TiO2 nanorods, which significantly improved the dielectric properties of the composite.
Article
Chemistry, Physical
Ping Wang, Shuyi Bao, Shuqian Qiao, Ce Li, Zhang Jiang, Hao Song, Yilin Wang, Qiuqiang Zhan, Ling Huang
Summary: We introduce a high-throughput method for generating lanthanide-doped upconversion nanoparticle (UCNP) arrays using polymer pen lithography (PPL). Instead of expensive materials, two types of polymers are employed, with one serving as the ink carrier and the other as the chelator for successful patterning of metal ions. The coordination between the chelator polymer and rare earth ions allows for good ink mobility. Additionally, small molecules with functional groups can also serve as chelators, expanding the ink library for PPL.
Article
Chemistry, Physical
Maria K. S. O. Abreu, Maria A. S. Silva, Dieric S. Abreu, Ana R. Richter, Regina C. M. de Paula, Vera R. L. Constantino, Igor F. Vasconcelos, Francisco G. S. de Oliveira, Acacio S. de Melo, Marcio A. Correa, Izaura C. N. Diogenes
Summary: This study improves the colloidal stability of CoFe2O4 in water media by encapsulating it in CMCG. The results show that after encapsulation, CoFe2O4 forms a polymer-caged MNPs aggregate with a negatively charged layer. Despite the dilution effect of CMCG, the material maintains magnetization.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Polymer Science
Dallas Kesler, Bhanuka P. Ariyawansa, Hemali Rathnayake
Summary: Metal oxide nanoparticle-reinforced polymers have attracted attention for their superior mechanical properties. This study investigated the effect of nanoscale reinforcements on polymer composites and found that a composite with 5 wt% ZnO nanorods exhibited improved elastic modulus, stiffness, and hardness. The viscoelastic response of the composite also showed enhanced performance to high impacts. However, the composites were still vulnerable to hypervelocity impact, although those reinforced with ZnO nanorods exhibited a cellular-like matrix with shock-induced voids.
Article
Nanoscience & Nanotechnology
Joshua M. Kubiak, Buxuan Li, Mathew Suazo, Robert J. Macfarlane
Summary: The distribution of filler particles within a polymer matrix nanocomposite significantly affects its properties and processability. This study presents a strategy for preparing functional composites with enhanced thermal conductivity. The thermal cross-linking of self-suspended polymer grafted nanoparticles is used to achieve homogeneously dispersed, non-percolating alumina particles in an organic matrix.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Jeong-Seok Mun, Ji-Hoon Woo, Yejin Ku, Hyun-Taek Oh, Jin Hyun Lee, Jin-Kyun Lee, Kanghyun Kim, Byeong-Gyu Park, Sangsul Lee
Summary: In this study, a dendritic polyphenol with a high glass transition temperature (Tg) was synthesized and found to have a stable amorphous nature. The high Tg of the molecule allowed for the formation of high-resolution microlithography patterns using lithographic techniques. Additionally, the molecule was derivatized into a fluoroalkylated molecule, which also produced high-resolution features under electron-beam lithographic conditions.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Physical
Umashankar Erigi, Umesh Dhumal, Mukta Tripathy
Summary: The study uses PRISM theory and molecular dynamics simulations to investigate the structure and phase behavior of polymer nanocomposites with nanorods. Both methods predict the formation of different aggregates based on the strength of polymer-nanorod interactions and show that the miscible region narrows with increasing nanorod aspect ratio. Results suggest that theory and simulations qualitatively complement each other but display quantitative differences.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Alejandro J. Da Silva Sanchez, Curtis Dobrowolski, Ana Cristian, Elisa Schrader Echeverri, Kun Zhao, Marine Z. C. Hatit, David Loughrey, Kalina Paunovska, James E. Dahlman
Summary: In order to predict the effectiveness of lipid nanoparticle (LNP) delivery systems in humans, researchers have investigated whether the mechanism of LNP uptake into cells is consistent across different species. Studies have shown that besides the interaction between apolipoprotein E (ApoE) and low-density lipoprotein receptor (LDLR), other interactions may also affect the targeting ability of LNPs.
Article
Nanoscience & Nanotechnology
Ankan Kumar Sarkar, Koushik Debnath, Himali Arora, Pankaj Seth, Nihar R. Jana, Nikhil R. Jana
Summary: The direct cytosolic delivery of large biomolecules bypassing endocytic pathways is a promising strategy for therapeutic applications. Recent research has shown that surface chemistry of carriers, nanoscale assembly, colloidal stability, and low surface charge are critical for non-endocytic uptake processes. The guanidinium-terminated polyaspartic acid micelle can deliver protein/DNA directly to the cytosol by forming a nano-assembly with <200 nm size and near-zero surface charge, highlighting the importance of size and colloidal properties for efficient cytosolic delivery of large biomolecules.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Multidisciplinary Sciences
Ekta Kamra, Tulika Prasad, Anam Rais, Bhawna Dahiya, Abhishek Sheoran, Aishwarya Soni, Suman Sharma, Promod K. Mehta
Summary: We used nano-based immuno-PCR assay to detect Mycobacterium tuberculosis biomarkers in urine extracellular vesicles of genitourinary TB patients. Our magnetic bead-coupled gold nanoparticle-based immuno-PCR showed higher sensitivity and specificity compared to other methods. This study has the potential to improve current diagnostic algorithms for genitourinary TB.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Physical
Wenjie Zhou, Yein Lim, Haixin Lin, Sangmin Lee, Yuanwei Li, Ziyin Huang, Jingshan S. Du, Byeongdu Lee, Shunzhi Wang, Ana Sanchez-Iglesias, Marek Grzelczak, Luis M. Liz-Marzan, Sharon C. Glotzer, Chad A. Mirkin
Summary: This study successfully assembled colloidal quasicrystals by exploiting the geometry of nanoscale decahedra and the programmable bonding characteristics of DNA immobilized on their facets. The process is enthalpy-driven, works over a range of particle sizes and DNA lengths, and is made possible by the energetic preference of the system to maximize DNA duplex formation and favor facet alignment. The resulting colloidal quasicrystals exhibit specific structures with stacking disorder providing thermodynamic stability.
Article
Polymer Science
Ashish Zore, Peng Geng, Michael R. Van De Mark
Summary: Studies on the interfacial behavior of pure aqueous nanoparticles have been limited due to the difficulty of preparing contaminant-free nanoparticles with narrow size distribution. Colloidal unimolecular polymers (CUPs) are a new type of single-chain nanoparticle that can be produced without surfactants and volatile organic contents. The behavior of CUP particles in water was studied using a maximum bubble pressure tensiometer, and it was found that the equilibrium surface tension decreased with increasing concentration and surface charge. The electrostatic repulsion between the particles influenced the surface tension, and at higher concentrations, surface charge condensation became dominant. The dynamic surface tension of the CUP particles indicated the influence of particle diffusion on the relaxation time, which was found to be similar to that of SDS.
Article
Green & Sustainable Science & Technology
Abhinay Mishra, Abdul Rahim Ferhan, Chee Meng Benjamin Ho, JooHyun Lee, Dong-Hwan Kim, Young-Jin Kim, Yong-Jin Yoon
Summary: Polymer-nanoparticle composites have been successfully fabricated by incorporating gold nanoparticles into a polymer scaffold, enabling the detection of thrombin with good sensitivity down to 0.01 ng/mL. The nanolobe architecture facilitates nanoparticle trapping while allowing molecular access to the nanoparticle surface, and the combination of metallic nanoparticles with a nonfouling polymer matrix allows for reliable biomolecular sensing.
INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING-GREEN TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Seongkyu Maeng, Sun Jae Park, Jaehwan Lee, Hyungdoh Lee, Jonghui Choi, Jeung Ku Kang, Himchan Cho
Summary: We propose a universal direct photocatalytic patterning method that can preserve the optical properties of nanocrystals and other emissive nanomaterials, while enhancing the photoluminescence quantum yield and photostability of certain materials. This method has the potential to pattern various functional materials and devices in a nondestructive and simple way.
Article
Chemistry, Multidisciplinary
Jing Qin, Guohai Liang, Bingxi Feng, Gen Wang, Na Wu, Yonghui Deng, Ahmed A. Elzatahry, Abdulaziz Alghamdi, Yongxi Zhao, Jing Wei
Summary: Using plant polyphenols as polymerizable ligands, water-dispersible CPs with tunable metal species and ultra-small diameter were synthesized through a covalent modification mediated coordination assembly strategy, which are highly water dispersible nanoparticles suitable for bioimaging, especially for tumor T1-weighted MR imaging.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Physical
Wendong Liu, Michael Kappl, Werner Steffen, Hans-Jurgen Butt
Summary: The addition of salt affects the shape of supraparticles, with salt concentration influencing the extent of crystallization. These changes in shape and structure are correlated with salt-dependent single colloid interaction forces. Understanding these interactions is crucial for assembly behavior during the drying process and for preparing complex supraparticles for specific applications.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Xiaoteng Zhou, Jie Liu, Wendong Liu, Werner Steffen, Hans-Juergen Butt
Summary: A stretchable superamphiphobic surface is reported in this study, which can maintain stable superliquid repellency even under high tensile strain by rearranging its microstructures. The surface exhibits high deformation resistance and retains its superamphiphobicity and morphology after multiple stretch-release cycles. This research contributes to the development of reusable and low-cost platforms for biochemical detection and lab-on-a-chip systems.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Ning-Ning Zhang, Hao-Ran Sun, Shuhan Liu, Yu-Chen Xing, Jun Lu, Fei Peng, Cheng-Long Han, Zhonglin Wei, Tianmeng Sun, Bai Yang, Kun Liu
Summary: The study presents a seed-mediated synthesis method for chiral gold nanooctopods with specific morphology, showing an influence on cellular uptake.
Article
Chemistry, Physical
Xiaolong Zheng, Wendong Liu, Shi Feng, Yongxian Yu, Yingdi Lv, Shengyang Tao
Summary: In this study, polyethyleneimine microcapsules were successfully prepared and their formation process was investigated. The obtained microcapsules showed strong adsorption capacity for Pd2+ and exhibited good catalytic activity and recycling characteristics in the Suzuki coupling reaction.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Multidisciplinary
Xingfu Tao, Yang Li, Linxiuzi Yu, Yinshu Zhang, Chenglong Han, Yang Yang, Hujun Qian, Zhongyuan Lu, Kun Liu
Summary: In this study, a high-curvature 2D polymerization method is proposed to form highly cross-linked amphiphilic Gemini monomer networks on the surfaces of nanoparticles. Selective etching of core-shell nanoparticles allows for the formation of 2D polymers as non-contacting ligands on yolk-shell structures with excellent shape retention and high surface accessibility. Furthermore, the 2D polymer ligands can be covalently linked to other functional molecules through copolymerization.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Biomedical
Nianzuo Yu, Feiran Zhang, Xiaoduo Tang, Yongshun Liu, Junhu Zhang, Bai Yang, Quan Wang
Summary: A microfluidic spotting-screening platform (MSSP) has been developed for controlling the effect of extracellular matrix on cell development. The MSSP can precisely control the behavior of mesenchymal stem cells, such as adhesion and differentiation, and provides a feasible and high-throughput platform for hydrogel-microarray-based materials.
ACTA BIOMATERIALIA
(2023)
Article
Chemistry, Multidisciplinary
Yajun Wang, Jingjie Nan, Huilong Ma, Jiajun Xu, Feifei Guo, Yufeng Wang, Yongye Liang, Junhu Zhang, Shoujun Zhu
Summary: A modular theranostic system combining NIR-II FGS and a sandwiched plasmonic chip (SPC) was developed for intraoperative detection and resection of tumor cells in lymph nodes with high sensitivity and selectivity. The system achieved accurate diagnosis and improved efficiency of cancer therapy.
Article
Chemistry, Multidisciplinary
Shi Feng, Cunliang Pan, Hongfei Ye, Wendong Liu, Wenbo Yang, Yingdi Lv, Shengyang Tao
Summary: Enhanced mixing in microchannels is achieved by using magnetic nonspherical particles (MNSPs), which generate secondary vortices with cyclical characteristics due to their shape. Increasing the rotation rate of MNSPs enlarges the secondary vortices, expanding the mixing zone and enhancing the mixing efficiency. Complementary micro-particle image velocimetry (mu PIV) analysis clarifies the mixing mechanism and demonstrates the potential of employing MNSPs as efficient mixers in lab-on-chip devices.
Article
Multidisciplinary Sciences
Xiaoduo Tang, Jingyan Ren, Xin Wei, Tao Wang, Haiqiu Li, Yihan Sun, Yang Liu, Mingli Chi, Shoujun Zhu, Laijin Lu, Junhu Zhang, Bai Yang
Summary: The authors have developed a hydrogel patch that releases carbon monoxide and nitric oxide gases on demand, which can provide timely blood supply for skin flap transplantation during surgery, reducing the incidence of flap necrosis and long-term functional loss.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Xingchen Cui, Zhezhi Liu, Bing Zhang, Xiaoduo Tang, Fuqiang Fan, Yu Fu, Junhu Zhang, Tieqiang Wang, Fanbao Meng
Summary: Actuators based on hydrogels are promising for biomimetic soft robots. However, their actuation process lacks perceptual capacity. This study proposes a fast photo-thermal responsive and self-sensory soft actuator based on a sponge-like hydrogel, demonstrating ultrafast response and self-sensing capabilities. Inspired by neuromuscular systems, a smart self-adaptive actuator is designed, enabling active perception and shape transformation. This sensory actuating hydrogel contributes to the development of artificial intelligent soft robotics with higher autonomy and complexity.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Feiran Zhang, Jiajun Xu, Chengbin Zhang, Yin Li, Jiawei Gao, Limei Qu, Songling Zhang, Shoujun Zhu, Junhu Zhang, Bai Yang
Summary: Accurate identification of tumor margins during cancer surgeries is essential, and a high-throughput detection technique is needed. The conventional histopathological analysis of frozen tissue sections often shows variability, especially in areas without trained pathologists. This study introduces a high-throughput three-dimensional histological electrophoresis device that utilizes tumor-specific proteins to identify and contour tumor margins intraoperatively. Testing on xenograft models and human cervical cancer models demonstrated the effectiveness of this approach. The device is expected to improve the accuracy and efficiency of diagnosing various cancers.
Article
Multidisciplinary Sciences
Feiran Zhang, Jiajun Xu, Ying Yue, Yajun Wang, Jianing Sun, Dong Song, Chengbin Zhang, Limei Qu, Shoujun Zhu, Junhu Zhang, Bai Yang
Summary: This study introduces a three-dimensional histological electrophoresis system, which can rapidly label and separate proteins within tissue sections during surgical excision of tumors, providing a more precise and automated pathological diagnosis for assessing tumor-positive margins.
Article
Chemistry, Multidisciplinary
Jingjie Nan, Yuan Chen, Weihong Sun, Ying Yue, Yuanyuan Che, Hongli Shan, Wei Xu, Bin Liu, Shoujun Zhu, Junhu Zhang, Bai Yang
Summary: This study developed a novel label-free and naked-eye readable microarray technique for quick antibody analysis. The technique is fast, accurate, and flexible, allowing for large-scale SARS-CoV-2 antibody detection and analysis of antibodies against multiple virus variants.
Article
Nanoscience & Nanotechnology
Yihan Sun, Manxuan Liu, Xiaoduo Tang, Yanmin Zhou, Junhu Zhang, Bai Yang
Summary: Probiotic therapy in infected wound healing is hindered by low viability and colonization efficiency. In this study, a culture-delivery live probiotics hydrogel dressing was developed to maintain the activity of probiotics and limit leakage, resulting in sustainable antimicrobial effects.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Hang Yu, Zhina Wu, Xingfu Bao, Xiaoduo Tang, Junhu Zhang, Yi Zhang, Min Hu
Summary: Orthodontic tooth movement (OTM) may cause orthodontically induced inflammatory root resorption (OIIRR), which affects tooth health and treatment stability. In this study, a composite hydrogel named CCOD-Trametinib (CCOD-Tra) was developed to prevent OIIRR. The CCOD-Tra hydrogel exhibited good biocompatibility, injectability, and sustained release of Trametinib (Tra). Animal and cell experiments demonstrated that CCOD-Tra effectively prevented OIIRR by inhibiting osteoclast differentiation and maturation through the ERK1/2 signaling pathway.