Article
Food Science & Technology
Pilar Espitia-Hernandez, Xochitl Ruelas-Chacon, Monica L. Chavez-Gonzalez, Juan A. Ascacio-Valdes, Antonio Flores-Naveda, Leonardo Sepulveda-Torre
Summary: Solid-state fermentation (SSF) can extract tannins from sorghum and release phenolic compounds as antioxidants, thereby improving the nutritional value and antioxidant activity of sorghum.
Article
Chemistry, Applied
Zijian Liang, Pangzhen Zhang, Yun Xiong, Stuart K. Johnson, Zhongxiang Fang
Summary: This study characterized the phenolic and carotenoid profiles of the Australian native bulb plant, Haemodorum spicatum, using HPLC-DAD-ESI-QTOF-MS/MS and HPLC-DAD. The results identified 40 phenolic compounds and 2 carotenoids, with 35 compounds being reported for the first time in H. spicatum.
Article
Biochemistry & Molecular Biology
Carolina Olivati, Yara Paula Nishiyama-Hortense, Natalia Soares Janzantti, Roberto da Silva, Ellen Silva Lago Vanzela, Sergio Gomez-Alonso
Summary: Dark chocolate coated raisins treated with extra virgin olive oil showed increased concentrations of flavan-3-ols and proanthocyanidins compared to just raisins. The chocolate coating also led to the emergence of new compounds. This combination resulted in a dark chocolate coated raisin with good sensory acceptance and a more complex phenolic composition, potentially positively contributing to its functional quality.
Article
Pharmacology & Pharmacy
Malgorzata Kozyra, Anna Biernasiuk, Magdalena Wiktor, Wirginia Kukula-Koch, Anna Malm
Summary: A comparative analysis was conducted on the flavonoids and phenolic acids composition in six species of Monarda from the Lamiaceae family. The results showed that these plants exhibited potential antioxidant and antimicrobial effects, making them potential sources of natural antioxidants and antimicrobial agents.
Article
Plant Sciences
Soraia I. Pedro, Tiago A. Fernandes, Angelo Luis, Alexandra M. M. Antunes, Jose C. Goncalves, Jorge Gominho, Eugenia Gallardo, Ofelia Anjos
Summary: This study evaluated the potential industrial applications of various Acacia species by examining their chemical composition, antioxidant, and antimicrobial properties. Among the studied species, A. pycnantha exhibited a higher concentration of total phenolic compounds and displayed notable antibacterial activity. Vibrational spectroscopy was a reliable method for distinguishing between species.
Article
Chemistry, Applied
Christof B. Steingass, Jonas Burkhardt, Vicky Baeumer, Keshav Kumar, Heiko Mibus-Schoppe, Jana Zinkernagel, Patricia Esquivel, Victor M. Jimenez, Ralf Schweiggert
Summary: Anthocyanins were characterized in red cabbage, sweet potato, and Tradescantia pallida leaves. Various non-, mono-, and diacylated cyanidins were identified in red cabbage. Sweet potato leaves contained mono- and diacylated cyanidin- and peonidin glycosides, while T. pallida leaves mainly contained tetra-acylated anthocyanin tradescantin. The thermal stability of red cabbage and purple sweet potato extracts surpassed that of a commercial food dye, but still fell short compared to the stability of Tradescantia extract.
Article
Food Science & Technology
Imelda N. Monroy-Garcia, Irma Edith Carranza-Torres, Pilar Carranza-Rosales, Maria Oyon-Ardoiz, Ignacio Garcia-Estevez, Jesus Fernando Ayala-Zavala, Javier Moran-Martinez, Ezequiel Viveros-Valdez
Summary: This study found that wild fruits such as Ehretia tinifolia and Sideroxylon lanuginosum are rich in antioxidants and exhibit antioxidant, antiproliferative, and digestive enzymatic inhibition activities. The extracts from these fruits contain beneficial phytochemicals and have potential for developing functional foods.
Article
Chemistry, Multidisciplinary
Joselena Ferreira, Giuseppina Negri, Maria Luiza Salatino, Dejair Message, Antonio Salatino
Summary: This study analyzed the chemical composition and antioxidant activity of M. subnitida geopropolis samples from inside and outside the nest in northeastern Brazil. The results showed that both samples contained 26 phenolic compounds, with the compounds being more abundant in the sample collected from inside the nest. Additionally, ellagitannins and phenylpropanoyl-O-benzoyl hexoses were reported for the first time. The antioxidant activity of the geopropolis sample collected from outside the nest was higher than that from inside.
Article
Biochemistry & Molecular Biology
Fadoua Asraoui, Ayoub Kounnoun, Hafssa El Cadi, Francesco Cacciola, Yassine Oulad El Majdoub, Filippo Alibrando, Filippo Mandolfino, Paola Dugo, Luigi Mondello, Adnane Louajri
Summary: The study investigated the chemical composition and antioxidant properties of leaf extracts from Globularia alypum L. from Morocco. The ethyl acetate extract showed higher phenolic and flavonoid contents, as well as stronger antioxidant activity compared to the chloroform extract. This plant serves as a rich source of natural antioxidants.
Article
Microbiology
Jaqueline Ferreira Campos, Thaliny Bonamigo, Paola dos Santos da Rocha, Vanessa Marina Branco Paula, Uilson Pereira dos Santos, Jose Benedito Perrella Balestieri, Denise Brentan Silva, Carlos Alexandre Carollo, Leticia M. Estevinho, Kely de Picoli Souza, Edson Lucas dos Santos
Summary: The chemical compositions and antimicrobial activity of propolis produced by Melipona quadrifasciata anthidioides and Scaptotrigona depilis were determined in this study. The propolis extracts contained phenolic compounds, diterpenes, and triterpenes. Both extracts demonstrated inhibitory effects against bacteria and fungi, with S. depilis extract showing better antimicrobial activity. This research suggests that propolis from these stingless bees has potential for the prevention or treatment of microbial infections.
Article
Food Science & Technology
Yara Paula Nishiyama-Hortense, Carolina Olivati, Jose Perez-Navarro, Reginaldo Teodoro Souza, Natalia S. Janzantti, Roberto Da-Silva, Isidro Hermosin-Gutierrez, Sergio Gomez-Alonso, Ellen Silva Lago-Vanzela
Summary: The study aimed to determine the phenolic compounds in the edible parts of BRS Carmem grapes harvested at two different stages of maturation. It was found that both mature and immature grapes contained high amounts of flavonols, anthocyanins, hydroxycinnamic acids derivatives, and stilbenes. The concentrations of these compounds were higher in the whole grapes compared to their skins, and higher in the seeds compared to the skins. Despite being immature, BRS Carmem grapes still exhibited a complex phenolic composition.
Article
Biochemistry & Molecular Biology
Marios C. Kyriacou, Chrystalla Antoniou, Youssef Rouphael, Giulia Graziani, Angelos Kyratzis
Summary: The research identified six critical stages in the ripening process of carob fruits, showing changes in sugar accumulation, total phenolic compounds, and condensed tannins during ripening. Antioxidant capacity was influenced by altitude and ripening stage.
Article
Chemistry, Applied
William Leonard, Pangzhen Zhang, Danyang Ying, Yun Xiong, Zhongxiang Fang
Summary: Extrusion of hempseed hull at different barrel temperature and screw speed led to increased total phenolic content, antioxidant activities, and inhibition of α-glucosidase and acetylcholinesterase. Interaction between extrusion parameters influenced the phenolic/flavonoid content, antioxidant activities, and enzyme inhibition. Various phenylpropionamides were identified, with N-trans-caffeoyltyramine showing significant positive correlation with biological activities.
Article
Chemistry, Multidisciplinary
Adonias Almeida Carvalho, Lucivania Rodrigues dos Santos, Jurema Santana de Freitas, Renato Pinto de Sousa, Ruth Raquel Soares de Farias, Gerardo Magela Vieira, Mahendra Rai, Mariana Helena Chaves
Summary: The aqueous fraction of Machaerium acutifolium leaves extract was analyzed and found to contain various flavonoids and phenolic compounds. The aqueous fraction exhibited significant antioxidant activity and a high total phenolic content.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Plant Sciences
Soraia I. Pedro, Tiago Rosado, Celina Barroca, Duarte Neiva, Vanesa Alonso-Herranz, Ana Gradillas, Antonia Garcia, Jorge Gominho, Eugenia Gallardo, Ofelia Anjos
Summary: Acacia spp. is an invasive species widely distributed in Portugal. It has been found that Acacia flowers contain high concentrations of phenolic compounds and flavonoids. The composition of these compounds varies among different species and flowering stages, and can be distinguished through analysis of FTIR-ATR spectra data of the extracts.
Article
Infectious Diseases
Isabella F. S. Figueiredo, Lorena G. Araujo, Raissa G. Assuncao, Itaynara L. Dutra, Johnny R. Nascimento, Fabricia S. Rego, Carolina S. Rolim, Leylane S. R. Alves, Mariana A. Frazao, Samilly F. Cadete, Luis Claudio N. da Silva, Joicy C. de Sa, Eduardo M. de Sousa, Waldir P. Elias, Flavia R. F. Nascimento, Afonso G. Abreu
Summary: The study showed that cinnamaldehyde has potential in treating sepsis by reducing inflammation, increasing cell production in bone marrow and spleen, and improving survival rates in animals.
Review
Endocrinology & Metabolism
Rosane Nassar Meireles Guerra, Claudia Regina Silva dos Santos Cunha, Marcela Patricia Macedo Belo Fort, Eremita Val Rafael, Rebeca Aranha Arrais e Silva Santos, Monica Virginia Viegas Lima-Aragao, Mayara Cristina Pinto Silva, Flavia Raquel Fernandes Nascimento
Summary: This study aimed to investigate the effects of gestational diabetes on the levels of immunoglobulin A (IgA) and cytokines in colostrum, as well as the potential impact of COVID-19 on the immunological characteristics of human milk. The results showed that gestational diabetes reduced the levels of IgA and other immunoreactive proteins in colostrum. However, data on the effects of the combination of gestational diabetes and COVID-19 infection on the composition of antibodies and cytokines in human milk are still limited and inconclusive.
CURRENT DIABETES REVIEWS
(2023)
Article
Infectious Diseases
Roberval Nascimento Moraes-Neto, Gabrielle Guedes Coutinho, Ana Caroline Santos Ataide, Aline de Oliveira Rezende, Camila Evangelista Carnib Nascimento, Rafaela Pontes de Albuquerque, Claudia Quintino da Rocha, Adriana Sousa Rego, Maria do Socorro de Sousa Cartagenes, Ana Lucia Abreu-Silva, Igor Victor Ferreira dos Santos, Cleydson Breno Rodrigues dos Santos, Rosane Nassar Meireles Guerra, Rachel Melo Ribeiro, Valerio Monteiro-Neto, Eduardo Martins de Sousa, Rafael Cardoso Carvalho
Summary: Mycobacterium abscessus subsp. massiliense is a bacteria that causes chronic infections, and new antimycobacterial agents are needed to combat it. In this study, the ethyl acetate fraction of Bixa orellana leaves and ellagic acid were found to have antimycobacterial and anti-inflammatory activities. In vitro and in vivo experiments showed that these substances exhibited antimicrobial effects against Mabs and reduced inflammation. The high binding affinities of ellagic acid to specific enzymes may explain its biological activities.
Article
Public, Environmental & Occupational Health
Iolanda Graepp-Fontoura, David Soeiro Barbosa, Volmar Morais Fontoura, Rosane Nassar Meireles Guerra, Solange de Araujo Melo, Maria Neyrian de Fatima Fernandes, Perpetua do Socorro Silva Costa, Sergiane Maia Maciel, Yara Andrade Goiabeira, Floriacy Stabnow Santos, Marcelino Santos-Neto, Leonardo Hunaldo dos Santos, Maria Aparecida Alves de Oliveira Serra, Ana Lucia Abreu-Silva
Summary: This study identified the spatial patterns of HVL/HIV coinfection in Brazil and found an increasing trend in the number of cases. The central-western region and the North and Northeast regions had higher rates of coinfection. This information can be used to target interventions and control measures to prevent new cases.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
(2023)
Article
Biochemistry & Molecular Biology
Anderson Franca da Silva, Josivan Regis Farias, Danielle Cristine Gomes Franco, Andrea Araruna Galiza, Elizangela Pestana Motta, Aluisio da Silva Oliveira, Cleydlenne Costa Vasconcelos, Maria do Socorro de Sousa Cartagenes, Claudia Quintino da Rocha, Mayara Cristina Pinto da Silva, Alberto Jorge Oliveira Lopes, Flavia Raquel Fernandes do Nascimento, Cristina Andrade Monteiro, Rosane Nassar Meireles Guerra
Summary: This study investigated the antifungal activity of ononin using in silico and in vitro assays as well as an alternative in vivo model. The results suggested that ononin has anti-Candida albicans activity and could be a potential candidate for new therapeutic alternatives.
Review
Parasitology
Irlla Correia Lima Lica, Gleycka Cristine Carvalho Gomes Frazao, Ranielly Araujo Nogueira, Maria Gabriela Sampaio Lira, Vitor Augusto Ferreira dos Santos, Joao Gustavo Mendes Rodrigues, Guilherme Silva Miranda, Rafael Cardoso Carvalho, Lucilene Amorim Silva, Rosane Nassar Meireles Guerra, Flavia Raquel Fernandes Nascimento
Summary: Human schistosomiasis is caused by helminths of the genus Schistosoma, and macrophages play a crucial role in immune regulation. These cells can acquire different phenotypes depending on the stimulus they receive.
Article
Virology
Eder M. S. Fialho, Emanoel M. Veras, Caroline M. de Jesus, Ricardo Khouri, Patricia S. Sousa, Marizelia R. C. Ribeiro, Luciana C. Costa, Lillian N. Gomes, Flavia R. F. Nascimento, Antonio A. M. Silva, Paulo V. Soeiro-Pereira
Summary: This study aims to assess the immuno-inflammatory profile of mothers and their children diagnosed with CZS. The results showed a correlation between the leukocyte profile of CZS+ children and their mothers, especially in monocytes. CZS+ children demonstrated normal HLA expression and higher hydrogen peroxide concentration.
Article
Infectious Diseases
Elizangela Pestana Motta, Josivan Regis Farias, Arthur Andre Castro da Costa, Anderson Franca da Silva, Alberto Jorge Oliveira Lopes, Maria do Socorro Sousa Cartagenes, Roberto Nicolete, Afonso Gomes Abreu, Elizabeth Soares Fernandes, Flavia Raquel Fernandes Nascimento, Claudia Quintino da Rocha, Cristina Andrade Monteiro, Rosane Nassar Meireles Guerra
Summary: This study evaluated the anti-Candida activity of the hydroalcoholic extract from the leaves of Vismia guianensis and found that it inhibited the virulence factors of the fungi. The main compound responsible for this activity was identified as vismione D.
Article
Biotechnology & Applied Microbiology
Tatielle Gomes Dias, Liliane dos Santos Rodrigues, Josivan Regis Farias, Ana Lucia Fernandes Pereira, Adriana Gomes Nogueira Ferreira, Marcelino Santos Neto, Richard Pereira Dutra, Aramys Silva Reis, Rosane Nassar Meireles Guerra, Valerio Monteiro-Neto, Marcia Cristina Goncalves Maciel
Summary: With the increasing resistance of bacteria to conventional antibiotics, researchers are turning to alternative strategies such as microbiota modulation to prevent and treat bacterial infections. This review examines the immunomodulatory effects of probiotics in bacterial infections based on an integrative analysis of scientific literature. The most commonly studied bacteria genera were Salmonella, Escherichia, Klebsiella, and Streptococcus, with Lactobacillus being the most frequently used probiotic genus, specifically Lactobacillus delbrueckii subsp. bulgaricus. Prophylactic treatment with probiotic concentrations equal to or greater than 8 log CFU/mL was commonly chosen, although there was heterogeneity in terms of effective treatment duration.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Biochemistry & Molecular Biology
Richard Pereira Dutra, Marcos Marinho de Sousa Jr, Maria Simone Pereira Maciel Mignoni, Karla Gabriela Mota de Oliveira, Euzineti Borges Pereira, Aline Santana Figueredo, Arthur Andre Castro da Costa, Tatielle Gomes Dias, Cleydlenne Costa Vasconcelos, Lucilene Amorim Silva, Aramys Silva Reis, Alberto Jorge Oliveira Lopes
Summary: In this study, the leishmanicidal activity and chemical composition of Brazilian Amazon red propolis were evaluated. The propolis exhibited a high concentration of phenolic compounds and inhibitory activity against Leishmania amazonensis. Additionally, a fraction of the propolis showed enhanced bioactivity and no cytotoxicity towards macrophages. The in silico study suggested that liquiritigenin may be the compound responsible for the leishmanicidal activity. These findings highlight the potential of Brazilian Amazon red propolis for the treatment of leishmaniasis.
Article
Plant Sciences
Angela Tamara Lemos Souza Barroqueiro, Marcia Cristina Goncalves Maciel, Andre Alvares Marques Vale, Mayara Cristina Pinto Silva, Andressa Caroline dos Santos Maia, Ana Paula Azevedo dos Santos, Johnny Ramos do Nascimento, Flavia Raquel Fernandes do Nascimento, Claudia Quintino Rocha, Elizabeth Soares Fernandes, Rosane Nassar Meireles Guerra
Summary: Babassu mesocarp aqueous extract (BAE) has antimicrobial and immunomodulatory effects, which can be used as a complementary treatment for infections, reducing mortality and inflammation.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Food Science & Technology
Gislane Romano Mendonca, Rodrigo Anacleto Pinto, Erika Almeida Praxedes, Virginia Kelly Goncalves Abreu, Richard Pereira Dutra, Alexsandra Fernandes Pereira, Tatiana de Oliveira Lemos, Aramys Silva dos Reis, Ana Lucia Fernandes Pereira
Summary: This study developed two new types of kombucha beverages using H. sabdariffa leaves and stems as raw materials and increased phenolic and flavonoid compounds and antioxidant activity through fermentation and flavoring. The results showed that the leaves and stems of H. sabdariffa are potential raw materials for kombucha production.
INTERNATIONAL JOURNAL OF GASTRONOMY AND FOOD SCIENCE
(2023)
