4.7 Article

Design, Synthesis, and Insecticidal Evaluation of New Benzoylureas Containing Isoxazoline and Isoxazole Group

Journal

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 59, Issue 9, Pages 4851-4859

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jf200395g

Keywords

Benzoylphenylureas; benzoyl urea; isoxazole; isoxazoline; insecticidal activity; insect growth regulator

Funding

  1. National Key Project for Basic Research [2010CB126106]
  2. National Natural Science Foundation of China [21072109]
  3. National Key Technology Research and Development Program [2011BAE06B05-3]

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Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by H-1 NMR and elemental analysis (or FIRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds were evaluated. Compounds I-1 and III-1 showed nearly the same level of insecticidal activity against Oriental armyworm as commercial insecticide Flucycloxuron and surprisingly exhibited much higher larvicidal activities against diamondback moth than Flucycloxuron.

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