Article
Agriculture, Multidisciplinary
Zhenglin Dong, Lan Li, Yiming Zhang, Liu Guo, Xin Wu, Yulong Yin, Dan Wan
Summary: Circadian iron administration affected iron absorption and storage in pigs. Evening iron supplementation may be a more effective pattern for iron utilization. The rhythmic system in the intestine, driven by the time, played an important role in this process.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Review
Nutrition & Dietetics
Regina Menezes, Paulo Matafome, Marisa Freitas, Maria-Teresa Garcia-Conesa
Summary: Polyphenols have anti-diabetic properties and can regulate biomarkers and metabolic pathways associated with diabetes. However, the current evidence is limited and contradictory, with small and variable effects. Future studies need to be improved to achieve consistent evidence of the anti-diabetic effects of polyphenols.
Article
Biochemistry & Molecular Biology
Bolun Sun, Panxue Zhang, Jinjie Zhang, Tao Huang, Chao Li, Wenge Yang
Summary: This study aimed to investigate the effects of glycosylation on the structure, physicochemical characteristics, and iron bioavailability of hemoglobin from Tegillarca granosa. The glycosylation process improved the hydrophilicity of hemoglobin, increased its antioxidant capacity, enhanced in vitro digestibility, and ultimately led to better iron absorption than the FeSO4.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Multidisciplinary Sciences
Cindy H. J. Yu, Petra C. Kienesberger, Thomas Pulinilkunnil, H. P. Vasantha Rupasinghe
Summary: This study examined the effects of polyphenol-rich apples on energy metabolism in high-fat diet-induced obese mice. The results showed that supplementation with DB apple did not improve obesity, high blood glucose levels, and lipid metabolism abnormalities. Future studies should increase the dosage and try different forms of supplementation.
SCIENTIFIC REPORTS
(2023)
Review
Biochemistry & Molecular Biology
Mithun Rudrapal, Siddhartha Maji, Shiv Kumar Prajapati, Payal Kesharwani, Prashanta Kumar Deb, Johra Khan, Randa Mohamed Ismail, Rani S. Kankate, Ranjan Kumar Sahoo, Shubham J. Khairnar, Atul R. Bendale
Summary: Cigarette smoking can cause life-threatening diseases such as lung cancer and pulmonary and cardiovascular diseases. One of the major health implications of smoking is the oxidative damage to cellular constituents, and dietary polyphenols have shown potential benefits in protecting against various chronic conditions.
Review
Food Science & Technology
Yilin Xing, Shanxing Gao, Xinyu Zhang, Jiachen Zang
Summary: Heme-containing proteins are promising dietary sources for iron supplementation with higher bioavailability and fewer side effects. They have been widely utilized as food ingredients and antibacterial agents. This review provides a detailed summary of the structural characterization of heme-containing proteins and highlights their recent applications as dietary iron sources in the field of food science and nutrition.
Article
Biotechnology & Applied Microbiology
Xiao-Li Zhang, Xiao-Qing Gong, Xin-Jian Su, Hai-Xia Yu, Si-Yuan Cheng, Jing-Wen Huang, Dan-Yang Li, Zhao-Long Lei, Ming-jun Li, Feng-wang Ma
Summary: In this study, it was found that MdRAD23D1 and MdPRP6 proteins in apple plants have opposite regulatory roles in drought stress. MdRAD23D1 levels increased under drought condition, accelerating the degradation of MdPRP6, while MdPRP6 negatively regulated drought response by regulating proline accumulation. Therefore, MdRAD23D1 and MdPRP6 together confer drought stress tolerance in apple plants.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Food Science & Technology
Dan Li, Yongli Yang, Xi Yang, Zichao Wang, Xiaolin Yao, Yurong Guo
Summary: This study evaluated the effects of complexation between whey protein isolate (WPI) and young apple polyphenols (YAP) on the bioavailability and anti-hyperglycemic activity of YAP. The results showed that complexation improved the bioavailability of YAP and enhanced its ability to alleviate postprandial blood glucose level increase. This suggests that co-complexation with WPI is an effective way to improve the functionality of YAP.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Food Science & Technology
Jason A. Wiesinger, Juan M. Osorno, Phillip E. McClean, Jonathan J. Hart, Raymond P. Glahn
Summary: Seed coat darkening after delayed harvest or prolonged storage reduces the commercial value of dry beans, but slow-darkening pinto beans have faster cooking times and higher bioavailable iron content. Lower procyanidin concentrations in pinto beans are strongly associated with faster cooking times and improved iron bioavailability.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Plant Sciences
Johanna I. I. Keigler, Jason A. A. Wiesinger, Sherry A. A. Flint-Garcia, Raymond P. P. Glahn
Summary: Maize is a staple food for communities with high levels of anemia, and enhancing its iron bioavailability through degermination could help alleviate iron deficiency. This study evaluated the effects of degermination on iron bioavailability in 52 diverse maize genotypes, showing that it increased in 30 genotypes while remaining unchanged or decreasing in the other 22. Phytate concentrations in maize flours were also reduced with degermination, but the relationship between phytate concentrations and iron bioavailability was complex.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Nutrition & Dietetics
Karla Damian-Medina, Dragan Milenkovic, Yolanda Salinas-Moreno, Karla Fabiola Corral-Jara, Luis Figueroa-Yanez, Erika Marino-Marmolejo, Eugenia Lugo-Cervantes
Summary: This study investigated the multi-genomic effects of black bean intake on adipose tissue and identified potential regulatory networks involved in type 2 diabetes mellitus. The results showed significant changes in gene expression following black bean consumption, with involvement in various biological pathways. Additionally, transcription factors may modulate their activity through interactions with black bean extract or cell signaling proteins. Therefore, black beans may have anti-diabetic protective effects by regulating gene expression.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Applied
Yianna Y. Zhang, Regine Stockmann, Ken Ng, James A. Broadbent, Sally Stockwell, Hafiz Suleria, Noor E. Karishma Shaik, Ranjith R. Unnithan, Said Ajlouni
Summary: This study aimed to identify enzymatically-derived pea peptides that enhance the bioavailability of Fe(III) by acting as solubilizing agents. The pea hydrolysates showed a strong iron-binding capacity of 5.3 mg/g lyophilized powder. The Fe(III)-binding peptides were separated and sequenced, with results indicating that they primarily belonged to the Vicilin family and were rich in Glu, Asn, Lys, and Leu. 15 novel peptides below 1.5 kDa were identified as potential candidates for enhancing iron bioavailability based on their relative abundance and physicochemical properties.
Article
Biochemistry & Molecular Biology
Shuddhanjali Roy, Tanushree Agarwal, Arup Das, Tanmoy Halder, Gouranga Upadhyaya, Binay Chaubey, Sudipta Ray
Summary: The C-terminal stretch in SbGPRP1 acts as an antimicrobial peptide by either binding to the bacterial membrane or targeting a specific protein on the membrane, causing membrane perturbation. The study shows the potential antimicrobial property of the C-terminal peptide against gram-positive bacteria and phytopathogen, and identifies a crucial 23 amino acid sequence for its antimicrobial activity. Further experiments demonstrate the interaction between C-SbGPRP1 and bacterial membrane protein, leading to membrane perturbation and antimicrobial activity.
PLANT MOLECULAR BIOLOGY
(2023)
Article
Chemistry, Applied
Ying Liu, Zhuo Wang, Abulimiti Kelimu, Sameh A. Korma, Ilaria Cacciotti, Huan Xiang, Chun Cui
Summary: In this study, a high iron-chelating ability (87.32%) egg yolk protein hydrolysate (EYPH) was prepared. Fractionation using 60% (v/v) ethanol concentration (E3 fraction) efficiently accumulated the iron-chelating peptides in EYPH. Characterization results revealed that iron mainly chelated with carboxyl, amino, and phosphate groups of peptides. Six iron-chelating peptides ranging from 1372.36 to 2937.04 Da were identified from the E3 fraction, and a hypothesized molecular model of DDSSSpSpSpSpSpSVLSK-Fe was simulated. In vitro stability determination showed that the E3-Fe chelate had good heat, alkalinity, and digestion tolerance, but relatively poor acid tolerance. Iron transport analysis demonstrated that iron in the E3-Fe complex would be more effectively absorbed in caco-2 cell membrane compared to iron salts, suggesting the potential application of the E3-Fe complex as iron supplements.
Article
Chemistry, Applied
Joana J. Costa, Felismina T. C. Moreira, Susana Soares, Elsa Branda, Nuno Mateus, Victor De Freitas, M. Goreti F. Sales
Summary: This study presents an innovative approach for monitoring astringent polyphenols in beverages using an electrochemical biosensor. The biosensor was constructed by adsorbing salivary alpha-amylase or proline-rich protein onto amined gold screen-printed electrodes. The sensor showed high sensitivity and quantitative monitoring capability for astringent compounds in wine samples.