Article
Food Science & Technology
Maria Eugenia Araujo Silva Oliveira, Luciana Ribeiro da Silva Lima, Millena Cristina Barros Santos, Nathalia Ferrari Fonseca de Sales, Renata Marenda Ferreira, Luiz Claudio Cameron, Jose Manoel Colombari Filho, Priscila Zaczuk Bassinello, Carlos Wanderlei Piler de Carvalho, Mariana Simoes Larraz Ferreira, Cristina Yoshie Takeiti
Summary: This study investigated the effects of short germination and milling on the physical properties, phenolic compounds, antioxidant activity, and amino acid composition of rice. The results showed that short germination and milling can improve the nutritional quality and antioxidant activity of rice. The husk + bran fraction had the highest level of total antioxidant activity, and the levels of glutamic acid and GABA were significantly increased. Short germination and milling can be an effective strategy to enhance the nutritional value of rice.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Chemistry, Applied
Jiangyi Luo, Ling Liang, Qinling Xie, Yixing Qiu, Sai Jiang, Yupei Yang, Lijuan Zhu, Yangfen Fu, Shenghuang Chen, Wei Wang, Hanwen Yuan
Summary: This study explored the differences in phytochemical composition, bioactive properties, and antioxidant activity of five citrus by-products in China. Essential compounds for identification were established, and the spectrum-effect relationship analysis revealed the differential markers contributing to the antioxidant activity. The results highlight the potential for enhancing and utilizing citrus by-products.
Article
Agriculture, Multidisciplinary
Sulagna Gupta, Wei Ning Chen
Summary: Okara, a by-product of the tofu and soymilk industries, was found to yield better results in total phenolic and flavonoid content after fermentation with Rhizopus oligosporus. Analysis showed a shift in isoflavones from glucoside forms to their respective aglycone forms post-fermentation, with fermented extracts having higher concentrations of genistein and daidzein, which are beneficial for health. The study suggests that fermented okara could be a sustainable solution for producing natural bioactive isoflavonoids.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Biochemistry & Molecular Biology
Zening Wang, Colin J. Barrow, Frank R. Dunshea, Hafiz A. R. Suleria
Summary: Five Australian grown pear varieties were selected for this study, with Beurre Bosc and Josephine de Malines exhibiting high levels of phenolic compounds, suggesting potential health benefits.
Article
Pharmacology & Pharmacy
Kohei Kawabata, Miya Kohashi, Shiori Akimoto, Hiroyuki Nishi
Summary: In this study, the photostability of felodipine (FL) medicine and its altered forms was evaluated. The residual amounts of FL after 24 h of UV irradiation were measured and two photoproducts were identified. The chemical structures of the photoproducts were determined using mass spectrometry analysis. The generation rates of the photoproducts were found to be dependent on the presence of aqueous media.
Article
Chemistry, Applied
Zsofia Birinyi, Dalma Reder, Adam Dios, Ilma R. Korponay-Szabo, Eva Hunyadi-Gulyas, Christakis George Florides, Angela Juhasz, Gyongyver Gell
Summary: The study focused on characterizing a wild and cultivated einkorn collection using proteomics, immune analytics, and bioinformatics analyses, revealing high diversity in immune response among different genotypes. Four genotypes with significantly reduced immune reactivity were selected for detailed proteomics characterization, highlighting the potential to improve the lifestyle of individuals with clinical conditions like non-celiac wheat sensitivity.
Review
Chemistry, Analytical
Khaja Moinuddin Shaik, Bhaskar Sarmah, Gaurav Suresh Wadekar, Pramod Kumar
Summary: This review discusses the recent detection of nitrosamine impurities in pharmaceutical products, including various detection methods, mechanisms of action, sample preparation techniques, and regulatory limits.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Review
Environmental Sciences
Aikaterini A. Zompra, Styliani A. Chasapi, Matthew S. Twigg, Karina Salek, Ioannis Anestopoulos, Alex Galanis, Aglaia Pappa, Tony Gutierrez, Ibrahim M. Banat, Roger Marchant, Stephen R. Euston, Mihalis I. Panayiotidis, Georgios A. Spyroulias
Summary: Synthetic surfactants, commonly used in various industries, have a negative impact on the environment due to their synthetic preparation. As a result, there is a growing interest in exploring natural sources of surfactants, which can be produced through environmentally friendly processes. Microbial production of such chemicals, however, often results in crude materials composed of multiple complex bioproducts. Therefore, advanced analytical methods are required for the extraction, identification, and characterization of biosurfactants.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Food Science & Technology
Antia Lestido-Cardama, Raquel Sendon, Juana Bustos, M. Isabel Santillana, Perfecto Paseiro Losada, Ana Rodriguez Bernaldo de Quiros
Summary: The study found that exposure to compounds from epoxy resin coatings through the consumption of canned food was low and below the established tolerable daily intake levels. A multiresidue method was developed based on HPLC-FLD and confirmed using LC-MS/MS to assess the migration of coating components into food items.
FOOD PACKAGING AND SHELF LIFE
(2021)
Review
Chemistry, Analytical
Gabriel Davi Marena, Matheus Aparecido dos Santos Ramos, Tais Maria Bauab, Marlus Chorilli
Summary: This review article collects important information on the physical, chemical, and biological properties of Amphotericin B (AmB) as well as the main analytical methods for quantifying and determining it. The article provides the scientific community with important information for choosing the best analysis method and ensuring the reliability of research results.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Bhoopendra Singh Kushwah, Mohit M. Thummar, Amrej Singh Yadav, Vivek Dhiman, Gananadhamu Samanthula
Summary: This study describes the forced degradation of benidipine and the separation and characterization of its degradation products using HPLC and LC-MS/MS. The developed method can be used for quality control of drugs in laboratories.
BIOMEDICAL CHROMATOGRAPHY
(2023)
Article
Biochemical Research Methods
Leena M. Patil, David H. Parkinson, Nathan R. Zuniga, Hsien-Jung L. Lin, Bradley C. Naylor, John C. Price
Summary: Offline peptide separation using HPLC is commonly used to enhance protein detection in LC-MS/MS. We developed a robust intact protein separation (IPS) method and found that it is especially effective in serum, while traditional peptide separation (PS) is more effective in tissues. Combining IPS and PS methods significantly increases protein detection, peptide sequence coverage, and detection of post-translational modifications.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Pharmacology & Pharmacy
Shreedhar S. Otari, Suraj B. Patel, Manoj M. Lekhak, Savaliram G. Ghane
Summary: This research investigated the phytochemical profile and bioactivities of Barleria terminalis and Calacanthus grandiflorus. The results showed the presence of phenolic compounds and phenylethanoid glycosides in these plants. Additionally, they exhibited potential antioxidant, enzyme inhibitory, and anti-diabetic activities. These findings provide a basis for further research and utilization of these plants.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Analytical
Jianmei Wang, Jinmin Zhang, Ngoc Thao Duyen Nguyen, Yu-An Chen, Jer-Tsong Hsieh, Xiaowei Dong
Summary: This study developed a new HPLC method to measure IR780 concentration in pharmaceutical formulations and a new LC-MS/MS method to measure IR780 concentration in tissue samples, particularly in liver and lung. These quantitative methods provide reliable measurements of IR780 in both formulations and biological samples, facilitating research on IR780 as a theranostic agent for cancer therapy and imaging.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Biochemistry & Molecular Biology
Akhtar Ali, Hanjing Wu, Eric N. Ponnampalam, Jeremy J. Cottrell, Frank R. Dunshea, Hafiz A. R. Suleria
Summary: The study characterized 12 widely used spices for their phenolic compounds, polyphenols, and antioxidant potential, revealing that clove and allspice had the highest total polyphenol content, black cumin and black pepper had the highest phosphomolybdate activity, and there was a positive correlation between phenolic compounds and antioxidant activities.