Article
Psychiatry
Leonid Braverman, Camil Fuchs, Abraham Weizman, Michael Poyurovsky
Summary: Evidence suggests a higher comorbidity rate of obsessive-compulsive disorder (OCD) in bipolar disorder (BD) patients, particularly in those experiencing bipolar depression (BP-D). A study found 26% of BD patients with their first depressive episode also had OCD, while 23.2% met criteria for subthreshold OCD. No differences in demographic and clinical variables were observed between BD patients with and without OCD. Further research is needed to explore the longitudinal course, treatment approaches, and outcomes of comorbid BP-D/OCD.
PSYCHIATRY RESEARCH
(2021)
Article
Psychiatry
Matteo Tonna, Margherita Trinchieri, Valeria Lucarini, Martina Ferrari, Massimo Ballerini, Paolo Ossola, Chiara De Panfilis, Carlo Marchesi
Summary: The study found that OCS in BD patients appear as a state-dependent phenomenon cycling with the mood phases, particularly exacerbating in the context of depressive and mixed states.
PSYCHIATRY RESEARCH
(2021)
Article
Clinical Neurology
Shruti S. Kinkel-Ram, William Grunewald, Shelby N. Ortiz, Joshua M. Magee, April R. Smith
Summary: This study revealed a bidirectional longitudinal relationship between eating disorders and obsessive-compulsive disorder, particularly in terms of cognitive symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Shruti S. Kinkel-Ram, William Grunewald, Shelby N. Ortiz, Joshua M. Magee, April R. Smith
Summary: The study found a bidirectional, longitudinal relationship between symptoms of eating disorders (ED) and obsessive-compulsive disorder (OCD), particularly in terms of cognitive symptoms. However, this longitudinal association was only present at certain time points.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Samantha N. Hellberg, Jonathan S. Abramowitz, Heidi J. Ojalehto, Megan W. Butcher, Jennifer L. Buchholz, Bradley C. Riemann
Summary: Depressive and obsessive-compulsive (OCD) symptoms often co-occur. Network analysis revealed the relationship between these symptoms, with key nodes including obsessions, negative affectivity, and cognitive-somatic changes. Unique connections were found between symmetry OCD symptoms and cognitive-somatic changes.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Mu-Hong Chen, Shih-Jen Tsai, Tung-Ping Su, Cheng-Ta Li, Wei-Chen Lin, Tzeng-Ji Chen, Tai-Long Pan, Ya-Mei Bai
Summary: Patients with obsessive-compulsive disorder (OCD) have a higher risk of ischemic stroke, especially middle-aged and elderly adults, but no significant difference in hemorrhagic stroke risk. The use of OCD medications does not appear to affect the occurrence of stroke.
Editorial Material
Clinical Neurology
Trevor. W. Robbins
Summary: This scientific commentary discusses the research conducted by Kim et al. on the unbalanced fronto-pallidal neurocircuit underlying set shifting in patients with obsessive-compulsive disorder, published in the journal Brain.
Article
Psychiatry
Mohammadarian Akbari, Reyhane Eghtedarian, Bashdar Mahmud Hussen, Solat Eslami, Mohammad Taheri, Soudeh Ghafouri-Fard
Summary: This study assessed the association between two polymorphisms of the ACE gene and the risk of bipolar disorder, schizophrenia, and obsessive-compulsive disorder. The results showed that these polymorphisms are associated with the risk of multiple psychiatric disorders.
Article
Psychology, Multidisciplinary
Vahid Khosravani, Farangis Sharifi Bastan, Ali Mohammadzadeh, Ali Amirinezhad, Seyed Mehdi Samimi Ardestani
Summary: The study found that patients with OCD, BD, and schizophrenia scored higher on early maladaptive schemas compared to healthy individuals, with variations in specific schemas across different disorders. Additionally, patients with these disorders may experience increased activation of early maladaptive schemas with heightened depression symptoms.
CURRENT PSYCHOLOGY
(2021)
Article
Health Care Sciences & Services
Yasushi Okamura, Yuki Murahashi, Yuna Umeda, Toshihiro Misumi, Takeshi Asami, Masanari Itokawa, Hirohiko Harima, Masafumi Mizuno, Hisato Matsunaga, Akitoyo Hishimoto
Summary: The study investigates the clinical differences between OCD patients with and without comorbid psychotic disorder and finds that OCD patients with comorbid psychotic disorder score lower on insight and functioning assessments.
Article
Psychiatry
Kun Li, Jiang Long, Wei Deng, Bochao Cheng, Jiaojian Wang
Summary: This study aimed to investigate the efficacy and risk factors of ECT in treating OCD patients in a high-volume center in China. The results showed that 57.1% of patients responded to ECT, with 52.4% reporting side effects. There was no statistically significant difference in demographics between the response and non-response groups, but patients with comorbid depression and schizophrenia related disorders showed poorer efficacy with ECT.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychiatry
Ilenia Pampaloni, Sabina Marriott, Enrico Pessina, Claire Fisher, Anusha Govender, Heba Mohamed, Augusta Chandler, Himanshu Tyagi, Lucy Morris, Stefano Pallanti
Summary: Obsessive Compulsive Disorder (OCD) is a common mental disorder that causes great suffering and affects social functioning and quality of life. However, it is often not adequately diagnosed or diagnosed with delay, leading to a long delay in receiving proper treatment. Various factors contribute to the complexity of OCD, making it important for clinicians to evaluate all aspects of the disorder.
COMPREHENSIVE PSYCHIATRY
(2022)
Article
Psychiatry
Matti Cervin, Maria Conceicao do Rosario, Leonardo F. Fontenelle, Ygor A. Ferrao, Marcelo C. Batistuzzo, Albina R. Torres, Rodolfo F. Damiano, Lorena Fernandez de la Cruz, Euripedes C. Miguel, David Mataix-Cols
Summary: Individuals with OCD have a higher risk of thinking about, attempting, and dying by suicide compared to the general population. Taboo obsessions, the general OCD factor, lifetime major depression, and lifetime substance use disorders significantly predict suicidality in patients with OCD. Taboo obsessions may explain a small proportion of the variance in suicidality and should be considered an independent risk factor.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychiatry
Masahiro Miyauchi, Naomi Matsuura, Keiichiro Mukai, Takuya Hashimoto, Shun Ogino, Kyosuke Yamanishi, Hisashi Yamada, Kazuhisa Hayashida, Hisato Matsunaga
Summary: This study investigated the association between attention-deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) in adult patients. The results showed that patients with ADHD had more severe symptoms, lower quality of life, and less improvement after treatment compared to those without ADHD or its traits.
COMPREHENSIVE PSYCHIATRY
(2023)
Review
Psychiatry
Dalainey H. Drakes, Emily J. Fawcett, Julia P. Rose, Jacqueline C. Carter-Major, Jonathan M. Fawcett
Summary: This study aimed to estimate the prevalence of obsessive-compulsive disorder (OCD) among individuals with a primary eating disorder (ED) diagnosis, finding the highest rates in anorexia nervosa binge-eating purging type patients. OCD was more prevalent in patient samples than those from the community.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Substance Abuse
Giulia Carreras, Alessandra Lugo, Chiara Stival, Andrea Amerio, Anna Odone, Roberta Pacifici, Silvano Gallus, Giuseppe Gorini
Summary: The COVID-19 lockdown in Italy had a significant impact on smoking habits, with some people starting or increasing smoking while others quitting or reducing smoking. The study found that younger age, occasional smoking, unemployment, and mental distress were associated with changes in smoking habits during the lockdown. Increased cigarette consumption during the lockdown was more likely among individuals experiencing poorer quality of life, reduced sleep quantity, increased anxiety, and depressive symptoms.
Article
Immunology
Cristina Genovese, Claudio Costantino, Anna Odone, Giuseppe Trimarchi, Vincenza La Fauci, Francesco Mazzitelli, Smeralda D'Amato, Raffaele Squeri, Alessandra Casuccio, Maria Pia Fantini, Antonio Azara, Silvana Castaldi, Elena Righi, Aida Bianco, Sofia Cosentino, Antonio Mistretta, Giovanni Gabutti, Rosa Prato, Giancarlo Icardi, Leila Fabiani, Roberta Siliquini, Guglielmo Bonaccorsi, Ida Torre, Maria Pavia, Paolo Villari, Gabriele Messina, Silvia Majori, Vincenzo Restivo, Davide Gori, Giovanna Deiana, Lucia Palandri, Giovanni Panciroli, Francesca Licata, Marina Marranzano, Armando Stefanati, Francesca Fortunato, Domenico Martinelli, Donatella Panatto, Daniela Amicizia, Annalucia Moretti, Damiana Di Risio, Gianluca Voglino, Fabrizio Bert, Chiara Lorini, Francesca Pennino, Gabriella Di Giuseppe, Andrea, Carolina Marzuillo, Cesare Rivieri, Nicola Nante, Stefano Tardivo, Francesca Moretti, Rosalia Ragusa, Carlo Signorelli
Summary: This study evaluated the knowledge, attitudes, and opinions of the general population in Italy regarding COVID-19 and influenza immunization. The findings showed that 17.5% of respondents were unlikely to accept a future COVID-19 vaccine, mainly due to a lack of trust, fear of side effects, or a lack of perceived susceptibility to the disease. While over 50% of participants were willing to receive flu vaccinations, only 28.2% had received it in the previous five seasons. Higher knowledge about COVID-19 and previous flu vaccination were significantly associated with the intention to be vaccinated against COVID-19 and influenza.
Article
Immunology
Michela Sabbatucci, Anna Odone, Carlo Signorelli, Andrea Siddu, Andrea Silenzi, Francesco Paolo Maraglino, Giovanni Rezza
Summary: The COVID-19 pandemic has had a significant impact on the Italian National Health System, leading to decreased routine childhood vaccine coverage rates. However, there has been an increase in chicken pox vaccination while recommended vaccinations have been moderately affected. Effective communication campaigns and educational programs are crucial to reinforce vaccination confidence and behavior during and beyond the COVID-19 era.
Article
Nutrition & Dietetics
Chiara Stival, Alessandra Lugo, Lavinia Barone, Giovanni Fattore, Anna Odone, Silvia Salvatore, Eugenio Santoro, Silvia Scaglioni, Piet A. van den Brandt, Silvano Gallus
Summary: Investigating the relationship between pediatric overweight, physical activity, and various factors is crucial for designing effective preventive programs. This study utilized data from surveys conducted in Lombardy, northern Italy in 2019. The prevalence of overweight and obesity was found to be 22.4% among 8-9-year-old children and 14.4% among 11-15-year-old adolescents. Males, children with higher birth weights, and those with obese parents had higher rates of overweight. Females and older adolescents were more likely to engage in inadequate physical activity. Obesity was associated with increased psychological distress and being victims of bullying. Increasing physical activity was found to decrease the frequency of mental health problems. Promoting prevention campaigns is necessary to ensure the physical and psychological well-being of children.
Article
Psychiatry
S. Nassir Ghaemi, Jules Angst, Paul A. Vohringer, Eric A. Youngstrom, James Phelps, Philip B. Mitchell, Roger S. McIntyre, Michael Bauer, Eduard Vieta, Samuel Gershon
Summary: This study proposes the Clinical Research Diagnostic Criteria for Bipolar Illness (CRDC-BP) for use in research studies, aiming to provide guidance for the diagnosis of major mental illnesses in the future.
INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS
(2022)
Article
Nutrition & Dietetics
Carlotta Micaela Jarach, Alessandra Lugo, Werner Garavello, Piet A. A. van den Brandt, Anna Odone, Christopher R. R. Cederroth, Cristina Bosetti, Silvano Gallus
Summary: Based on a case-control study conducted in northern Italy, we found that moderate-to-high intake of caffeine and butter, as well as high intake of poultry, prosciutto, and legumes, were inversely associated with tinnitus onset. Other food items, including cereals, red meat, fish, vegetables, and fruit, did not show any significant relationship. The variety of food consumed also decreased the risk of tinnitus. These findings highlight the importance of diet in tinnitus onset.
Article
Environmental Sciences
Marinella Bertolotti, Marta Betti, Fabio Giacchero, Chiara Grasso, Genny Franceschetti, Margherita Carotenuto, Anna Odone, Guglielmo Pacileo, Daniela Ferrante, Antonio Maconi
Summary: The mortality rate of COVID-19 patients varied between different waves of the pandemic. Patients admitted during the first wave had a higher risk of mortality compared to those admitted during the second and third waves. Older age, more severe disease, and the need for oxygen therapy were identified as strong risk factors for poor prognosis.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Andrea Aguglia, Giovanni Pietro Corsini, Alessandra Costanza, Andrea Berti, Edoardo Bruno, Andrea Escelsior, James Sanvi, Alice Trabucco, Eleonora Vai, Andrea Amerio, Gianluca Serafini, Mario Amore
Summary: The aim of this study is to identify the main sociodemographic and clinical correlates associated with frequent service users (FSUs) in an Italian psychiatric emergency department. The results showed that FSUs were more likely to be single, younger, with an earlier onset, and have a longer length of hospitalisation compared to non-FSUs. They were also more prone to bipolar disorder, cluster B personality disorder, substance use disorder, and non-suicidal self-injuries. Furthermore, FSUs were more likely to be discharged against medical advice or have escape attempts from the psychiatric ward.
Article
Nutrition & Dietetics
Andrea Amerio, Andrea Escelsior, Eleonora Martino, Antonella Strangio, Costanza Giacomini, Elisa Montagna, Andrea Aguglia, Marina Bellomo, Samir Giuseppe Sukkar, Daniele Saverino
Summary: This study reveals that there is an increased immune response and inflammatory state in patients with anorexia nervosa, which is correlated with the presence of autoantibodies for hypothalamic antigens. The study also suggests that the inflammatory state decreases with the duration of the disease.
Review
Neurosciences
Andrea Amerio, Eleonora Vai, Edoardo Bruno, Alessandra Costanza, Andrea Escelsior, Anna Odone, Domenico De Berardis, Andrea Aguglia, Gianluca Serafini, Mario Amore, Seyyed Nassir Ghaemi
Summary: Despite the pandemic triggering a wave of research, few studies have looked into the impact of COVID-19 on Italy's community-based mental health care system. This study aimed to summarize existing evidence and also drew from daily clinical practice. Despite reduced hospital care, community mental health centers promoted continuity of care through teleconsultation, leading to lower risk of deterioration and hospitalization for patients. This model received satisfaction from both patients and mental health workers.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
(2023)
Article
Neurosciences
Andrea Amerio, Luca Magnani, Carlo Castellani, Irene Schiavetti, Gabriele Sapia, Francesca Sibilla, Rita Pescini, Rosaria Casciaro, Federico Cresta, Andrea Escelsior, Alessandra Costanza, Andrea Aguglia, Gianluca Serafini, Mario Amore, Riccardo Ciprandi
Summary: The study aimed to investigate the relationship between CF and affective temperaments, taking into account the relevance of ionic balances in neural excitability as a potential neurobiological basis for temperamental expression. The study involved 55 adult CF patients and evaluated various factors including sociodemographic, clinical and therapeutic characteristics, temperamental and personality dispositions, and depressive and anxiety symptoms. The results showed that a hyperthymic temperament was protective against psychopathology, while other temperaments were associated with positive psychopathological history.
Article
Health Care Sciences & Services
Andrea Amerio, Andrea Escelsior, Eleonora Martino, Antonella Strangio, Andrea Aguglia, Matteo Marcatili, Benedetta Conio, Samir Giuseppe Sukkar, Daniele Saverino
Summary: The aim of this study was to evaluate the correlation between circulating SIRT1 and leptin, ghrelin, body mass index (BMI), and IgG reactive to hypothalamic antigens in anorexia nervosa (AN). Results showed that serum SIRT1 levels were increased in AN patients and decreased with the duration of illness. There was a negative correlation between SIRT1 and leptin/BMI, and a positive correlation between SIRT1 and ghrelin/IgG specific for hypothalamic antigens. These findings suggest that SIRT1 may serve as a clinical/biochemical parameter related to AN.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Andrea Amerio, Antimo Natale, Giovanni Battista Gnecco, Alessio Lechiara, Edoardo Verrina, Davide Bianchi, Laura Fusar-Poli, Alessandra Costanza, Gianluca Serafini, Mario Amore, Andrea Aguglia
Summary: The study aimed to compare sociodemographic and clinical characteristics, as well as emotional and behavioral dimensions, between males and females with borderline personality disorder (BPD). The findings showed that male BPD patients had more involuntary hospitalizations and higher substance abuse rates, while female BPD patients had more medication abuse. Additionally, females exhibited higher levels of alexithymia, hopelessness, and sensory sensitivity, and employed certain coping strategies more frequently. These gender differences highlight the importance of developing specific and differential treatments for males and females with BPD.
MEDICINA-LITHUANIA
(2023)
Article
Psychiatry
G. Mosconi, G. P. Vigezzi, P. Bertuccio, A. Amerio, A. Odone
Summary: This study aims to assess the short- and long-term impacts of transitioning to retirement on depression risk and suicidality in older adults across Europe. The results show that the risk of depression decreases in the first few years after retirement, but increases after 10 years. Suicidality risk only increases 5 years or more after retirement.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2023)
Article
Geriatrics & Gerontology
Paola Bertuccio, Giacomo Pietro Vigezzi, Giansanto Mosconi, Silvano Gallus, Anna Odone
Summary: This study analyzed data from 27 European countries and Israel to explore the impact of retirement on smoking habits. The results showed that the risk of smoking was higher 10 years or more before retirement, but decreased after retirement. The number of cigarettes smoked per day also decreased among smokers after retirement.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)