Article
Neurosciences
Zhishuai Jin, Sizhu Huyang, Lichen Jiang, Yajun Yan, Ming Xu, Jinyu Wang, Qixiong Li, Daxing Wu
Summary: The study revealed that individuals with congenital amusia exhibit increased interhemispheric functional connectivity in the posterior part of the default mode network, particularly in the posterior superior temporal gyrus and posterior cingulate cortex, which were negatively correlated with music perception ability. These findings suggest that the immature state of the default mode network may serve as a reliable neural marker for amusia.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Neuroimaging
Jing Chen, Dalong Sun, Yonghui Shi, Wei Jin, Yanbin Wang, Qian Xi, Chuancheng Ren
Summary: In this study, static and dynamic voxel-mirrored homotopic connectivity (VMHC) were analyzed in stroke patients and healthy controls, revealing significant alterations in VMHC in different brain regions of stroke patients. A negative correlation was found between dynamic VMHC and FMA scores.
BRAIN IMAGING AND BEHAVIOR
(2021)
Article
Neurosciences
Yi-Dan Shi, Hui-Ye Shu, Li-Qi Liu, Shi-Qi Li, Xu-Lin Liao, Yi-Cong Pan, Ting Su, Li-Juan Zhang, Min Kang, Ping Ying, Yi Shao
Summary: Patients with morbid obesity and meibomian gland dysfunction exhibit altered functional connectivity in specific brain areas, which may be related to their clinical presentations.
Article
Neurosciences
Guanjie Hu, Honglin Ge, Kun Yang, Dongming Liu, Yong Liu, Zijuan Jiang, Xiao Hu, Chaoyong Xiao, Yuanjie Zou, Hongyi Liu, Xinhua Hu, Jiu Chen
Summary: The study investigates the alterations of brain regional function and intrinsic functional connectivity in patients with frontal glioma and explores the correlation between these alterations and cognition. It suggests that glioma causes regional dysfunction and disturbs long-distance functional connectivity, and these changes are related to cognitive functions.
Article
Psychiatry
Qing Chen, Yanmeng Bi, Weixin Yan, Shuhui Wu, Ting Xia, Yuhua Wang, Sha Huang, Chuying Zhou, Shuwen Xie, Shanshan Kuang, Wen Kong, Zhiping Lv
Summary: This study aimed to investigate the interhemispheric information synergy ability in major depressive disorder (MDD) patients using the VMHC method and explore the potential clinical diagnostic value of VMHC metric. The results showed that MDD patients had decreased VMHC values in the bilateral middle frontal gyrus, fusiform gyrus, medial superior frontal gyrus, and precentral gyrus compared to healthy controls. In addition, the VMHC value of the bilateral fusiform gyrus was positively correlated with the total HAMD score. SVM analysis demonstrated high performance in distinguishing MDD patients from healthy controls using a combination of all clusters.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Neurosciences
Yinhuan Xu, Yan Zhang
Summary: Prior studies have shown that obsessive-compulsive disorder (OCD) can lead to anatomical and functional changes in the brain. However, the altered functional synchronization between the two hemispheres in OCD patients remains unclear. In this study, using voxel-mirrored homotopic connectivity (VMHC), researchers found decreased VMHC in various brain regions of OCD patients compared to healthy controls, including the cerebellum, temporal gyrus, and putamen. The study also revealed negative correlations between VMHC values and symptom severity and disease duration.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Clinical Neurology
T. Pattyn, L. Schmaal, F. Van den Eede, L. Cassiers, B. W. Penninx, B. C. G. Sabbe, D. J. Veltman
Summary: This study found that panic disorder patients had lower brain activity in response to angry faces, driven mainly by the autonomic subtype. While no significant differences were found in other brain regions, the use of a subtype approach can help advance our neurobiological understanding of panic disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Neurosciences
Yi Cheng, Xiao-Lin Chen, Ling Shi, Si-Yu Li, Hui Huang, Pei-Pei Zhong, Xiao-Rong Wu
Summary: This study investigated the changes in functional connections between the left and right hemispheres of patients with high myopia (HM) and healthy controls (HCs) using resting functional magnetic resonance imaging (fMRI) based on voxel-mirrored homotopic connectivity (VMHC). The results showed that the interhemispheric functional connections in certain brain regions were disrupted in patients with HM. This provides valuable information for understanding the neural mechanism of high myopia.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Biology
Eva Y. W. Cheung, Y. F. Shea, Patrick K. C. Chiu, Joseph S. K. Kwan, Henry K. F. Mak
Summary: Previous studies have shown abnormal functional connectivity in patients with MCI and AD compared to HC. The current study used VMHC to differentiate VD from other Alzheimer's related neurodegenerative diseases, finding specific patterns of VMHC maps for VD, AD, and MCI. Combining VMHC values improved diagnostic accuracy for VD, AD, and MCI from HC in ROC analysis.
Article
Clinical Neurology
Danian Li, Hanyue Zhang, Yujie Liu, Xinyu Liang, Yaoping Chen, Yanting Zheng, Shijun Qiu, Ying Cui
Summary: The study revealed altered functional connectivity among key brain regions in Major Depressive Disorder (MDD) patients, including the default mode network, the central executive network, the limbic system, and the cerebellum. Increased functional connectivity between the right posterior cingulate cortex and the right inferior frontal gyrus may be useful for characterizing the pathophysiology of MDD and the functional correlates of phonemic verbal fluency deficits in MDD.
FRONTIERS IN NEUROLOGY
(2021)
Article
Neuroimaging
Ke Song, Ya-Li Lv, Li-juan Yang, Peng Lv, Bo Ren, Jun Tian, Dao-qing Wei, Huan Li, Yi Shao
Summary: This study used the VMHC method to investigate changes in interhemispheric functional connectivity in patients with ON. The results showed significantly reduced VMHC values in several brain regions of ON patients compared to healthy controls. Additionally, negative correlations were found between VMHC values in certain brain regions and visual acuity and depression scores. These altered regions also showed high diagnostic value in distinguishing ON patients from healthy controls.
BRAIN IMAGING AND BEHAVIOR
(2023)
Article
Neurosciences
Mohammad H. Afzali, Alain Dagher, Josiane Bourque, Sean Spinney, Patricia Conrod
Summary: The study found specific and predictive relationships between changes in default mode network activity and depressive symptoms during adolescence in a longitudinal adolescent cohort, controlling for potential neural markers of risk.
BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING
(2022)
Article
Neurosciences
Zhi Wen, Yan Kang, Yu Zhang, Huaguang Yang, Baojun Xie
Summary: This study aimed to investigate the interhemispheric functional connectivity alterations in adolescents with idiopathic congenital nystagmus and early blindness. The results showed increased values in several brain regions, including the middle frontal gyri, frontal eye field, and cerebellum, in the nystagmus group compared to the control group. However, no correlation was found between these connectivity changes and the duration of disease or degree of blindness.
Article
Clinical Neurology
Guo Zheng, Zhang Yingli, Chen Shengli, Zhou Zhifeng, Peng Bo, Hou Gangqiang, Qiu Yingwei
Summary: This study found that in patients with recurrent MDD, there is a significant decrease in inter-hemispheric homotopic functional connectivity in the bilateral medial prefrontal cortex, as well as impaired microstructural integrity in the anterior corpus callosum. These alterations are correlated with depression severity, suggesting a region-specific interhemispheric dysconnectivity in MDD.
FRONTIERS IN NEUROLOGY
(2022)
Article
Psychiatry
Shaojia Lu, Jiamin Shao, Qian Feng, Congchong Wu, Zhe Fang, Lili Jia, Zheng Wang, Shaohua Hu, Yi Xu, Manli Huang
Summary: This study investigated the brain functional differences between individuals with and without anhedonia in major depressive disorder (MDD). The results showed that MDD patients with anhedonia exhibited increased functional connectivity in the bilateral superior frontal gyrus and decreased functional connectivity in the bilateral middle temporal gyrus and inferior parietal lobule compared to healthy controls. These findings suggest neurobiological differences between different subtypes of depression in MDD.
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)