Article
Psychology, Clinical
Delainey L. Wescott, Peter L. Franzen, Brant P. Hasler, Megan A. Miller, Adriane M. Soehner, Stephen F. Smagula, Meredith L. Wallace, Martica H. Hall, Kathryn A. Roecklein
Summary: This study aims to clarify the nature and extent of hypersomnolence in seasonal affective disorder (SAD) using multiple measurements. The results suggest that hypersomnolence is not a poor characterization of SAD, and self-reported hypersomnia captures multiple sleep disruptions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Julia Fabienne Sandkuehler, Sarah Brochhagen, Paul Rohde, Rosa Clara Muscheidt, Teja Wolfgang Groemer, Helge Mueller, Jan Markus Brauner
Summary: This study assessed the feasibility and effectiveness of BROAD light therapy as a treatment for seasonal affective disorder (SAD). The results showed that BROAD light therapy was similarly effective as the standard of care, without confining participants to a specific time in front of a light box.
DEPRESSION AND ANXIETY
(2022)
Review
Cell Biology
Anusha Shankar, Cory T. Williams
Summary: The development of diurnal animal models is essential for studying seasonal affective disorder (SAD), as these models are more likely to mimic circadian disruption and show promise in replicating SAD-like behaviors. Current research suggests that diurnal rodents exhibit changes in behavior similar to SAD when exposed to short photoperiods or dim-light conditions, and these symptoms can be alleviated by exposure to bright light. Further research on the orexinergic system in diurnal models could provide insights into potential mechanisms underlying SAD.
DISEASE MODELS & MECHANISMS
(2021)
Article
Clinical Neurology
Raphael O. Cerqueira, Carolina Ziebold, Daniel Cavalcante, Giovany Oliveira, Javiera Vasquez, Juan Undurraga, Alfonso Gonzalez-Valderrama, Ruben Nachar, Carlos Lopez-Jaramillo, Cristiano Noto, Nicolas Crossley, Ary Gadelha
Summary: This study compares patients with affective and non-affective psychosis (A-FEP and NA-FEP) in a Latin American sample. The findings suggest that characteristics of FEP patients could be utilized to enhance diagnosis and inform treatment decisions.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Neurosciences
Helle Ostergaard Madsen, Shakoor Ba-Ali, Ida Hageman, Henrik Lund-Andersen, Klaus Martiny
Summary: In this study, light therapy was found to reduce depressive symptoms and improve subjective wellbeing and sleep quality in patients with severe visual impairment or blindness. However, some participants experienced side effects related to eye safety. Close attention should be paid to eye safety concerns during the treatment process.
ACTA NEUROPSYCHIATRICA
(2021)
Article
Psychiatry
Anibal Fonte, Bruno Coutinho
Summary: The study found a statistically significant association between seasonal affective disorder and psychiatric morbidity, emphasizing the importance of the Seasonal Pattern Assessment Questionnaire in screening for related disorders.
Article
Neurosciences
Carla Iorio, Francesca Pacitti, Alessandro Rossi, Paola Iorio, Assunta Pompili
Summary: Seasonal Affective Disorder (SAD) is a specific subtype of Major Depressive Disorder (MDD) characterized by a seasonal pattern. This study aimed to investigate the cognitive processing of emotional stimuli in women with SAD, and found impaired declarative memory and attentional bias for negative emotional stimuli in SAD patients.
Article
Psychiatry
Marta Migo, Kendra Simpson, Amy Peters, Kristen K. Ellard, Tina Chou, Andrew A. Nierenberg, Darin D. Dougherty, Thilo Deckersbach
Summary: By dimensionally analyzing symptom severity in patients with bipolar disorder, more accurate differences in neural responses to emotional stimuli can be captured. There is a correlation between symptom severity and brain activation, with depression severity associated with increased activation in various brain regions and mania severity associated with both increased and decreased activation.
PSYCHIATRY RESEARCH
(2022)
Review
Psychiatry
Andre Do, Victor W. Li, Samantha Huang, Erin E. Michalak, Edwin M. Tam, Trisha Chakrabarty, Lakshmi N. Yatham, Raymond W. Lam
Summary: The study aimed to evaluate the efficacy and safety of blue-light therapy in seasonal and non-seasonal major depressive disorder. It was found that the efficacy of blue-light therapy in treating these conditions remains unproven, and further standardized and long-term clinical trials are needed.
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
(2022)
Article
Environmental Sciences
I-Peng Chen, Chun-Chao Huang, Hui-Chun Huang, Fan-Pei Gloria Yang, Kai-Ting Ko, Yun-Tse Lee, Fang-Ju Sun, Shen-Ing Liu
Summary: This study assessed the efficacy of bright light therapy (BLT) in treating non-seasonal major depressive disorder. The results showed that morning light therapy did not significantly reduce depressive symptoms, possibly due to the small sample size. However, the study had strengths as it was conducted in a warmer climate and included diverse Asian participants. Future research should consider factors such as drug response, antidepressive regimens, duration of BLT, and natural daylight in the environment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Clinical Neurology
Kathryn A. Roecklein, Peter L. Franzen, Delainey L. Wescott, Brant P. Hasler, Megan A. Miller, Shannon D. Donofry, Caitlin M. DuPont, Sarah M. Gratzmiller, Scott P. Drexler, W. Michael Wood-Vasey, Paul D. Gamlin
Summary: A retinal subsensitivity to environmental light may trigger Seasonal Affective Disorder (SAD) under low wintertime light conditions. The study found that SAD patients had significantly decreased responses to light in winter compared to controls, highlighting the seasonal variation in melanopsin driven non-visual responses to light as a potential risk factor for SAD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Clinical Neurology
Lea Bertrand, Marie-Pia d'ortho, Eve Reynaud, Michel Lejoyeux, Patrice Bourgin, Pierre A. Geoffroy
Summary: The study focused on Seasonal Affective Disorder (SAD) and found that REM sleep is significantly increased in both acute and remitted phases of the disorder. This suggests that REM sleep alterations could serve as trait markers for the diagnosis and treatment of SAD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Paola Salvatore, Ross J. Baldessarini, Harimandir K. Khalsa, Mauricio Tohen
Summary: The study analyzed psychopathological details of prodromes leading to first-lifetime psychotic episodes and found that these features could predict and distinguish final diagnoses of MDD, BD-I, and SzAffD. The findings highlight the value of early psychopathology in predicting final diagnoses of major affective and schizoaffective disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Allison Costello, Katrina Linning-Duffy, Carleigh Vandenbrook, Kevin Donohue, Bruce F. O'Hara, Antony Kim, Joseph S. Lonstein, Lily Yan
Summary: This study investigated the effects of bright light therapy (BLT) on sleep/wakefulness, daily rhythms, and the wakefulness-promoting orexin/hypocretin system in Nile grass rats. The results showed that the BLT group exhibited better wakefulness during light treatment, improved nighttime sleep quality, and enhanced daily rhythm entrainment compared to controls. The impact of BLT on the orexin system varied by sex and brain region. These findings suggest that diurnal grass rats could serve as a valuable model for studying the neural mechanisms underlying the therapeutic effects of BLT.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Medicine, General & Internal
Barbara Nussbaumer-Streit, Kylie Thaler, Andrea Chapman, Thomas Probst, Dietmar Winkler, Andreas Soennichsen, Bradley N. Gaynes, Gerald Gartlehner
Summary: Evidence on the effectiveness of second-generation antidepressants (SGAs) in treating seasonal affective disorder (SAD) is limited, with only one small trial showing a non-significant effect compared with placebo. Further research, including larger randomized controlled trials (RCTs), is needed to strengthen the evidence base in this area. Data on adverse events were sparse, making it difficult to draw firm conclusions about the safety of SGAs for SAD.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Clinical Neurology
S. J. M. Druiven, E. Knapen, B. W. J. H. Penninx, N. Antypa, R. A. Schoevers, H. Riese, Y. Meesters
JOURNAL OF AFFECTIVE DISORDERS
(2019)
Article
Psychology, Clinical
Annet H. van Bergen, Sanne Verkooijen, Annabel Vreeker, Lucija Abramovic, Manon H. Hillegers, Annet T. Spijker, Erik Hoencamp, Eline J. Regeer, Stefan E. Knapen, Rixt F. Riemersma-van der Lek, Robert Schoevers, Anja W. Stevens, Peter F. J. Schulte, Ronald Vonk, Rocco Hoekstra, Nico J. van Beveren, Ralph W. Kupka, Iris E. C. Sommer, Roel A. Ophoff, Rene S. Kahn, Marco P. M. Boks
PSYCHOLOGICAL MEDICINE
(2019)
Article
Psychology, Clinical
Stella J. M. Druiven, Johanna H. M. Hovenkamp-Hermelink, Stefan E. Knapen, Jeanine Kamphuis, Benno C. M. Haarman, Brenda W. J. H. Penninx, Niki Antypa, Ybe Meesters, Robert A. Schoevers, Harriette Riese
DEPRESSION AND ANXIETY
(2020)
Article
Sport Sciences
Melanie Knufinke, Arne Nieuwenhuys, Sabine A. E. Geurts, Els I. S. Most, Maarten H. Moen, Kamiel Maase, Anton M. L. Coenen, Marijke C. M. Gordijn, Michiel A. J. Kompier
Summary: Research suggests that athletes often have poor sleep quality, but combining fixed sleep schedules with light regulation may lead to more consolidated sleep. Light regulation improved self-reported sleep onset latency and subjective sleep quality, especially with a strict sleep-wake schedule. However, less obtrusive methods should be explored to enhance protocol compliance.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2021)
Letter
Biology
Ybe Meesters, Danielle Starreveld, Esmee Verwijk, Harm-Pieter Spaans, Marijke C. M. Gordijn
JOURNAL OF BIOLOGICAL RHYTHMS
(2020)
Letter
Clinical Neurology
S. E. Knapen, G. L. J. Onderwater, K. I. Roon
ACTA NEUROLOGICA BELGICA
(2020)
Article
Psychology, Clinical
Stefan E. Knapen, Peng Li, Rixt F. Riemersma-van der Lek, Sanne Verkooijen, Marco P. M. Boks, Robert A. Schoevers, Frank A. J. L. Scheer, Kun Hu
Summary: The study found sex- and scale-dependent alterations in fractal activity regulation in patients with bipolar disorder. Specifically, female patients and siblings had smaller fractal exponents at larger time scales, while male patients had larger exponents, and a higher weekly depression score was associated with a lower fractal exponent in the subsequent week.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
R. Lok, G. Zerbini, M. C. M. Gordijn, D. G. M. Beersma, R. A. Hut
SCIENTIFIC REPORTS
(2020)
Article
Psychiatry
Yoram K. Kunkels, Harriette Riese, Stefan E. Knapen, Rixt F. Riemersma-van der Lek, Sandip V. George, Arie M. van Roon, Robert A. Schoevers, Marieke Wichers
Summary: Early-warning signals have been utilized to predict transitions in various research fields, including predicting mood transitions in bipolar disorder patients. Actigraphy data and spectral analysis showed promise in predicting upcoming transitions in mood episodes, though further studies are needed to improve effectiveness in identifying upcoming bipolar episode onsets.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Biology
Piyumi Kahawage, Marie Crowe, John Gottlieb, Holly A. Swartz, Lakshmi N. Yatham, Ben Bullock, Maree Inder, Richard Porter, Andrew A. Nierenberg, Ybe Meesters, Marijke Gordjin, Bartholomeus C. M. Haarman, Greg Murray
Summary: Social distancing/lockdown policies during the COVID-19 pandemic may disrupt social rhythms and challenge circadian function, particularly in individuals with mood disorders. This qualitative study explored participants' subjective experiences of social disruption, identifying themes such as loss of daily activities, role of social interaction, altered time perception, and disruption to motivation and associated psychological effects. These findings suggest the concept of 'psychological drift' as a potential focus for future research.
CHRONOBIOLOGY INTERNATIONAL
(2022)
Article
Endocrinology & Metabolism
Jan-Frieder Harmsen, Jakob Wefers, Daniel Doligkeit, Luc Schlangen, Bas Dautzenberg, Pascal Rense, Dirk van Moorsel, Joris Hoeks, Esther Moonen-Kornips, Marijke C. M. Gordijn, Wouter D. van Marken Lichtenbelt, Patrick Schrauwen
Summary: The study found that bright lighting during the day and dim lighting at night can alter postprandial substrate handling, energy expenditure, and thermoregulation of overweight insulin-resistant individuals. Differences in light intensity have effects on various metabolic parameters and body temperature, indicating the importance of the indoor light environment for metabolic health in at-risk populations.
Article
Psychiatry
Piyumi Kahawage, Ben Bullock, Denny Meyer, John Gottlieb, Marie Crowe, Holly A. Swartz, Lakshmi N. Yatham, Maree Inder, Richard J. Porter, Andrew A. Nierenberg, Ybe Meesters, Marijke Gordijn, Bartholomeus C. M. Haarman, Greg Murray
Summary: This study investigated the impact of disrupted social rhythms on mood symptoms among individuals with mood disorders during the COVID-19 pandemic. The results showed that lower social rhythmicity was associated with more severe depressive symptoms, supporting the social zeitgeber hypothesis.
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
(2022)
Article
Biology
R. Lok, T. Woelders, M. C. M. Gordijn, M. J. van Koningsveld, K. Oberman, S. G. Fuhler, D. G. M. Beersma, R. A. Hut
Summary: Increased light exposure during wakefulness is associated with improved sleep quality, manifested as reduced time awake, increased time in NREM sleep, and increased power of delta waves on the electroencephalogram.
JOURNAL OF BIOLOGICAL RHYTHMS
(2022)
Article
Biology
Marina Cecilia Gimenez, Michelle Luxwolda, Eila G. Van Stipriaan, Pauline P. Bollen, Rieks L. Hoekman, Marthe A. Koopmans, Praveen R. Arany, Michael R. Krames, Anne C. Berends, Roelof A. Hut, Marijke C. M. Gordijn
Summary: In Western societies, people's indoor lifestyle and limited exposure to sunlight can have negative effects on their health and well-being. This study investigated the benefits of near-infrared light exposure in improving well-being and health, especially in winter when sunlight is less available. The results highlight the potential of incorporating near-infrared light technology into daily life for a healthier society.
Article
Sport Sciences
Yoram K. Kunkels, Stefan E. Knapen, Marij Zuidersma, Marieke Wichers, Harriette Riese, Ando C. Emerencia
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2020)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)