Article
Psychiatry
Ying Xiong, Robert Karlsson, Jie Song, Kaarina Kowalec, Christian Rueck, Robert Sigstroem, Lina Jonsson, Caitlin C. Clements, Evelyn Andersson, Julia Boberg, Cathryn M. Lewis, Patrick F. Sullivan, Mikael Landen, Yi Lu
Summary: This study aims to investigate the genetic overlap between treatment response and resistance in individuals with major depressive disorder (MDD), and provides evidence for the heritability of treatment-related phenotypes. It highlights the overall genetic profile of lithium-sensitivity in treatment-resistant depression (TRD), offering a genetic explanation for the efficacy of lithium in treating TRD.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Psychology, Clinical
Victoria Rodriguez, Luis Alameda, Diego Quattrone, Giada Tripoli, Charlotte Gayer-Anderson, Edoardo Spinazzola, Giulia Trotta, Hannah E. Jongsma, Simona Stilo, Caterina La Cascia, Laura Ferraro, Daniele La Barbera, Antonio Lasalvia, Sarah Tosato, Ilaria Tarricone, Elena Bonora, Stephane Jamain, Jean-Paul Selten, Eva Velthorst, Lieuwe de Haan, Pierre-Michel Llorca, Manuel Arrojo, Julio Bobes, Miguel Bernardo, Celso Arango, James Kirkbride, Peter B. Jones, Bart P. Rutten, Alexander Richards, Pak C. Sham, Michael O'Donovan, Jim Van Os, Craig Morgan, Marta Di Forti, Robin M. Murray, Evangelos Vassos
Summary: This study suggests that combining polygenic risk scores (PRS) for severe psychiatric disorders with prediction models for psychosis phenotypes can improve discrimination ability and enhance our understanding of these phenotypes. PRS may have potential usefulness in specific populations such as those at high risk or in the early stages of psychosis.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Medicine, Research & Experimental
Kosar Hooshmand, David Goldstein, Hannah C. Timmins, Tiffany Li, Michelle Harrison, Michael L. Friedlander, Craig R. Lewis, Justin G. Lees, Gila Moalem-Taylor, Boris Guennewig, Susanna B. Park, John B. Kwok
Summary: This study identified genetic loci associated with paclitaxel-induced chemotherapy-induced peripheral neuropathy (CIPN) through a genome-wide association study. Further analysis revealed the potential involvement of axon development and regeneration pathways in CIPN.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Psychology, Clinical
David T. Liebers, Mehdi Pirooznia, Andrea Ganna, Fernando S. Goes
Summary: The study demonstrates that psychiatric polygenic risk scores can modestly improve the distinction between BD and MDD cases based on clinical grounds, potentially providing utility for subjects at the extremes of the distribution or those with poorly measured clinical symptoms.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Zhengliang Sun, Liangzhe Meng, Yuhe Yao, Yanhong Zhang, Baohui Cheng, Yan Liang
Summary: This study characterized the MLP family in tomatoes through genome-wide evolutionary analysis and gene expression analysis. The findings revealed the distribution and potential functions of 34 SlMLP genes in the tomato genome. Additionally, the presence of cis-regulatory elements associated with stress and growth responses in the promoter regions of these genes suggests their involvement in various biological processes. Subcellular localization further showed that some SlMLP proteins are localized in the cytoplasm.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Clinical Neurology
Yang Yang, Qian Cui, Fengmei Lu, Yajing Pang, Yuyan Chen, Qin Tang, Di Li, Ting Lei, Zongling He, Shan Hu, Jiaxin Deng, Huafu Chen
Summary: The study revealed abnormal functional connectivity patterns of DMN subsystems in patients with bipolar disorder during major depressive episodes, and these abnormalities were associated with high levels of pessimism, highlighting the importance of pathological mechanisms in this disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Robert Sigstrom, Kaarina Kowalec, Lina Jonsson, Caitlin C. Clements, Robert Karlsson, Axel Nordenskjold, Erik Palsson, Patrick F. Sullivan, Mikael Landen
Summary: This study examined the association between polygenic liabilities for major depressive disorder, bipolar disorder, and schizophrenia with response to electroconvulsive therapy (ECT). The results suggest that greater polygenic liabilities for major depressive disorder are associated with less improvement, while greater polygenic liabilities for bipolar disorder are associated with greater improvement after ECT.
AMERICAN JOURNAL OF PSYCHIATRY
(2022)
Article
Genetics & Heredity
Adrian I. Campos, Shinichi Namba, Shu-Chin Lin, Kisung Nam, Julia Sidorenko, Huanwei Wang, Yoichiro Kamatani, Ling-Hua Wang, Seunggeun Lee, Yen-Feng Lin, Yen-Chen Anne Feng, Yukinori Okada, Peter M. Visscher, Loic Yengo
Summary: Simulations and applications to real data show that adjustment of genome-wide association analyses for polygenic scores increases the statistical power for discovery across all ancestries, suggesting an analytical strategy for future studies in underrepresented populations.
Article
Clinical Neurology
Zongchang Li, David Li, Xiaogang Chen
Summary: This study shows differences in genetic association between bipolar I disorder (BD-I) and bipolar II disorder (BD-II) with schizophrenia (SCZ) and major depressive disorder (MDD). The study finds that BD-II is more polygenic compared to BD-I, SCZ, and MDD, and there is substantial polygenic overlap between BD-I and SCZ, as well as between BD-I and MDD. The study also identifies specific shared genetic loci between BD subtypes and SCZ or MDD.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Hematology
Joey Ward, Ngoc-Quynh Le, Suryakant Suryakant, Jennifer A. Brody, Philippe Amouyel, Anne Boland, Rosemary Bown, Breda Cullen, Stephanie Debette, Jean-Francois Deleuze, Joseph Emmerich, Nicholas Graham, Marine Germain, Jana J. Anderson, Jill P. Pell, Donald M. Lyall, Laura M. Lyall, Daniel J. Smith, Kerri L. Wiggins, Jose Manuel Soria, Juan Carlos Souto, Pierre-Emmanuel Morange, Nicholas L. Smith, David-Alexandre Tregouet, Maria Sabater-Lleal, Rona J. Strawbridge
Summary: Major depressive disorder (MDD) is associated with an increased risk of venous thromboembolism (VTE), while bipolar disorder (BD) and schizophrenia (SCZ) are not. This study aimed to determine if genetic predisposition to MDD, BD, or SCZ is associated with an increased risk of VTE. The results showed a positive association between genetic predisposition to MDD and the risk of VTE, independent of known risk factors.
Article
Behavioral Sciences
Diana Schendel, Thomas Munk Laursen, Clara Albinana, Bjarni Vilhjalmsson, Christine Ladd-Acosta, Margaret Danielle Fallin, Kelly Benke, Brian Lee, Jakob Grove, Amy Kalkbrenner, Linda Ejlskov, David Hougaard, Jonas Bybjerg-Grauholm, Marie Baekvad-Hansen, Anders D. Borglum, Thomas Werge, Merete Nordentoft, Preben Bo Mortensen, Esben Agerbo
Summary: The study found that a history of mental disorders in the family or a high autism polygenic risk score are associated with autism spectrum disorder risk. The risk of autism was not substantially altered after considering both family psychiatric history and individual genetic susceptibility. While genetic risk did not overlap with family history risk, the two factors are best viewed as complementary measures of autism family-based risk.
Article
Biochemistry & Molecular Biology
Paul Debes, Nikolai Piavchenko, Annukka Ruokolainen, Outi Ovaskainen, Jacqueline E. Moustakas-Verho, Noora Parre, Tutku Aykanat, Jaakko Erkinaro, Craig R. Primmer
Summary: Sexual maturation timing is influenced by factors such as growth and body condition, with complex interactions between environmental and genetic effects. The causality between male and female maturation processes may differ, and the vgll3 gene has a significant impact on maturation and body condition.
Article
Genetics & Heredity
Yasser Al-Sarraj, Eman Al-Dous, Rowaida Z. Taha, Dina Ahram, Fouad Alshaban, Mohammed Tolfat, Hatem El-Shanti, Omar M. E. Albagha
Summary: Autism spectrum disorder (ASD) is a neurodevelopmental disease with genetic factors playing a crucial role. A GWAS in the Middle Eastern population of Qatar identified multiple genetic loci associated with ASD, some near genes implicated in ASD or related neurodevelopmental disorders. Further functional studies and replication are needed to better understand the genetic architecture of ASD.
Article
Immunology
Michael D. E. Sewell, Lorena Jimenez-Sanchez, Xueyi Shen, Amelia J. Edmondson-Stait, Claire Green, Mark J. Adams, Olivia M. Rifai, Andrew M. McIntosh, Donald M. Lyall, Heather C. Whalley, Stephen M. Lawrie
Summary: Major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD) share both common and distinct genetic risk factors, which are associated with peripheral abnormalities. Peripheral markers associated with these disorders are both shared and disorder-specific, suggesting potential underlying pathophysiological mechanisms in major psychiatric disorders.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Review
Neurosciences
Leanna M. Hernandez, Minsoo Kim, Gil D. Hoftman, Jillian R. Haney, Luis de la Torre-Ubieta, Bogdan Pasaniuc, Michael J. Gandal
Summary: Researchers discuss the opportunities and challenges of high-throughput transcriptomic profiling in the human brain, and how it can help pinpoint mechanisms underlying genetic risk for psychiatric disorders. They propose systematic approaches for integrating different levels of genetics, genomics, and phenomics, including combining spatially resolved gene expression with human neuroimaging maps. Results emphasize the importance of understanding gene expression regulation across human brain development in the pathogenesis of psychiatric diseases.
BIOLOGICAL PSYCHIATRY
(2021)
Article
Psychology, Clinical
Ole Koehler-Forsberg, Robert Keers, Rudolf Uher, Joanna Hauser, Wolfgang Maier, Marcella Rietschel, Peter McGuffin, Anne E. Farmer, Katherine J. Aitchison, Ole Mors
Summary: This study suggests that there may be correlations between personality traits and antidepressant treatment response, but these correlations may be confounded by differential rates of discontinuation.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Fabio Panariello, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Diana De Ronchi, Alessandro Serretti, Chiara Fabbri
Summary: This study aimed to identify factors associated with side effects of psychotropic drugs in a real-world setting enriched with treatment-resistant depression (TRD) patients. Results showed that the severity of depressive symptoms was associated with total, psychic, and neurological side effects, while autonomic side effects were higher in patients with somatic comorbidities and lower in patients receiving trazodone. Multivariate analyses revealed that depressive symptom severity was associated with psychic and total side effects, generalized anxiety disorder (GAD) with neurological side effects, and somatic comorbidities remained associated with autonomic side effects. Trazodone was associated with lower side effects and with augmentation treatments. Augmentation therapies showed opposite effects depending on response status, i.e. increased or decreased the risk of side effects in responders and non-responders/resistant patients, respectively.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2023)
Article
Psychology, Clinical
Megan Skelton, Ewan Carr, Joshua E. J. Buckman, Molly R. Davies, Kimberley A. Goldsmith, Colette R. Hirsch, Alicia J. Peel, Christopher Rayner, Katharine A. Rimes, Rob Saunders, Janet Wingrove, Gerome Breen, Thalia C. Eley
Summary: There is significant variation in patient symptom trajectories during psychological therapy for depression and anxiety. Identifying these trajectories can help guide clinical decisions and improve patient outcomes.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Respiratory System
Nicola Andrea Marchi, Geoffroy Solelhac, Mathieu Berger, Jose Haba-Rubio, Nadia Gosselin, Peter Vollenweider, Pedro Marques-Vidal, Julius Popp, Armin von Gunten, Martin Preisig, Bogdan Draganski, Raphael Heinzer
Summary: Using data from the HypnoLaus study, we found that the relationship between obstructive sleep apnoea (OSA) and cognitive decline in the elderly population is controversial. Our results showed that lower mean peripheral oxygen saturation during sleep and longer time spent asleep with SpO2 <90% were associated with steeper declines in cognitive scores. This study provides evidence of the contribution of OSA and nocturnal hypoxaemia to cognitive decline in the elderly population.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Clinical Neurology
Nicola Andrea Marchi, Mathieu Berger, Geoffroy Solelhac, Virginie Bayon, Jose Haba-Rubio, Julie Legault, Cynthia Thompson, Nadia Gosselin, Peter Vollenweider, Pedro Marques-Vidal, Armin von Gunten, Marie-Pierre Francoise Strippoli, Martin Preisig, Bogdan Draganski, Raphael Heinzer
Summary: Research has found conflicting results regarding the relationship between obstructive sleep apnea and cognitive functioning in older adults, and the moderating factors of this association have not been well studied. This study investigated the association between obstructive sleep apnea and cognitive functioning in older adults, as well as the moderating effects of age, sex, apolipoprotein E4, and obesity on this association. The findings suggest that apolipoprotein E4 carriers and obese individuals may be more vulnerable to the negative effects of severe obstructive sleep apnea on processing speed.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Psychiatry
Jesper Norgaard Kjaer, Tine Holm, Trine Ellegaard, Sissel Madsen, Eva Lorentzen, Ane Bjerg Christensen, Vibeke Bliksted, Ole Mors, Signe Dolmer
Summary: The Transdiagnostic Self-injury Interview (TSI) is a new measure that assesses the onset, frequency, methods, and severity of non-suicidal self-injury. This study demonstrated the feasibility and criterion validity of TSI, as well as its clinical correlates and interrater reliability.
NORDIC JOURNAL OF PSYCHIATRY
(2023)
Article
Anesthesiology
Isabelle Rouch, Marie-Pierre F. Strippoli, Jean-Michel Dorey, Setareh Ranjbar, Bernard Laurent, Armin von Gunten, Martin Preisig
Summary: This study aimed to explore the associations between major depressive disorders, anxiety disorders, personality traits, and early-life traumatic events with chronic pain. The results showed that neuroticism and extraversion were associated with the incidence of chronic pain, while major depressive disorders were associated with the persistence of chronic pain. Therefore, psychotherapy and pharmacotherapy may decrease the risk and persistence of chronic pain.
Article
Clinical Neurology
Georgios D. Argyropoulos, Foteini Christidi, Efstratios Karavasilis, Peter Bede, Anastasia Antoniou, Georgios Velonakis, Ioannis Seimenis, Nikolaos Kelekis, Nikolaos Smyrnis, Olympia Papakonstantinou, Efstathios Efstathopoulos, Panagiotis Ferentinos
Summary: This study investigated the neuroanatomical profile of polarity subphenotypes in euthymic bipolar disorder patients, and found abnormalities in cortical thickness and volume associated with onset polarity and predominant polarity. Specifically, onset polarity was found to have an impact on gray matter volume in the left middle frontal gyrus, while both onset polarity and predominant polarity were associated with cortical thickness abnormalities in various regions.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
Article
Psychiatry
Geoffroy Solelhac, Mathieu Berger, Marie-Pierre F. Strippoli, Nicola Andrea Marchi, Aurelie Stephan, Jean-Marie Petit, Virginie Bayon, Theo Imler, Jose Haba-Rubio, Tifenn Raffray, Peter Vollenweider, Pedro Marques-Vidal, Gerard Waeber, Damien Legar, Francesca Siclari, Pierre A. Geoffroy, Martin Preisig, Raphael Heinzer
Summary: This study aimed to investigate the sleep differences between different subtypes of major depressive disorder (MDD). The study found that current melancholic MDD was associated with decreased sleep quality and increased wake after sleep onset, while remitted unspecified MDD was associated with increased rapid eye movements density.
PSYCHIATRY RESEARCH
(2023)
Article
Neurosciences
Brett N. Adey, Johnathan Cooper-Knock, Ahmad Al Khleifat, Isabella Fogh, Philip van Damme, Philippe Corcia, Philippe Couratier, Orla Hardiman, Russell McLaughlin, Marc Gotkine, Vivian Drory, Vincenzo Silani, Nicola Ticozzi, Jan H. Veldink, Leonard H. van den Berg, Mamede de Carvalho, Susana Pinto, Jesus S. Mora S. Pardina, Monica Povedano Panades, Peter M. Andersen, Markus Weber, Nazli A. Basak, Christopher E. Shaw, Pamela J. Shaw, Karen E. Morrison, John E. Landers, Jonathan D. Glass, Patrick Vourc'h, Richard J. B. Dobson, Gerome Breen, Ammar Al-Chalabi, Ashley R. Jones, Alfredo Iacoangeli
Summary: This study explores the relationship between CAV1/2 genes and ALS. The expression of CAV1 and CAV2 genes is found to be higher in ALS patients compared to controls, and carriers of CAV1/2 enhancer mutations show improved survival and slower progression of the disease.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2023)
Biographical-Item
Medicine, General & Internal
Peter McGuffin
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Critical Care Medicine
Callum Jackson, Iain Stewart, Tatiana Plekhanova, Peter S. Cunningham, Andrew L. Hazel, Bashar Al-Sheklly, Raminder Aul, Charlotte E. Bolton, Trudie Chalder, James D. Chalmers, Nazia Chaudhuri, Annemarie B. Docherty, Gavin Donaldson, Charlotte L. Edwardson, Omer Elneima, Neil J. Greening, Neil A. Hanley, Victoria C. Harris, Ewen M. Harrison, Ling-Pei Ho, Linzy Houchen-Wolloff, Luke S. Howard, Caroline J. Jolley, Mark G. Jones, Olivia C. Leavy, Keir E. Lewis, Nazir Lone, Michael Marks, Hamish J. C. McAuley, Melitta A. McNarry, Brijesh Patel, Karen Piper-Hanley, Krisnah Poinasamy, Betty Raman, Matthew Richardson, Pilar Rivera-Ortega, Sarah L. Rowland-Jones, Alex Rowlands, Ruth M. Saunders, Janet T. Scott, Marco Sereno, Ajay M. Shah, Aarti Shikotra, Amisha Singapuri, Stefan C. Stanel, Mathew Thorpe, Daniel G. Wootton, Thomas Yates, R. Gisli Jenkins, Sally J. Singh, William D-C Man, Christopher E. Brightling, Louise Wain, Joanna C. Porter, A. A. Roger Thompson, Alex Horsley, Philip L. Molyneaux, Rachael A. Evans, Samuel E. Jones, Martin K. Rutter, John F. Blaikley, PHOSP-COVID Study Collaborative Grp
Summary: This study investigated the prevalence and nature of sleep disturbance after discharge following hospital admission for COVID-19 and found that sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness. Targeting sleep disturbance might be beneficial in treating the post-COVID-19 condition.
LANCET RESPIRATORY MEDICINE
(2023)
Article
Psychology, Clinical
Megan Skelton, Ana Catarino, Stephanie Brown, Ewan Carr, Molly R. Davies, Alicia J. Peel, Christopher Rayner, Gerome Breen, Thalia C. Eley
Summary: This study explores the trajectory of patient symptom and functional impairment during one-to-one internet-delivered therapy and finds that they have similar characteristics and are consistent with findings from face-to-face therapy. The results highlight the importance of personalizing therapy in terms of suitability and continuation.
BEHAVIOUR RESEARCH AND THERAPY
(2023)
Article
Neurosciences
Alish B. Palmos, Christopher Hubel, Kai Xiang Lim, Avina K. Hunjan, Jonathan R. I. Coleman, Gerome Breen
Summary: The study found that BMI and childhood trauma have a significant impact on major depressive disorder (MDD) and inflammation, but no correlation was found between inflammation and MDD. Moreover, the results showed a strong causal influence of BMI on inflammation, and a bidirectional influence between childhood trauma and MDD.
BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE
(2023)
Article
Neurosciences
Abigail R. ter Kuile, Christopher Hubel, Rosa Cheesman, Jonathan R. I. Coleman, Alicia J. Peel, Daniel F. Levey, Murray B. Stein, Joel Gelernter, Christopher Rayner, Thalia C. Eley, Gerome Breen
Summary: The research finds that self-reported trauma has a heritable component, and genetic characteristics may influence exposure to and interpretations of environmental factors. By analyzing genetic correlations, the study identifies specific traits related to the genetic factors of childhood maltreatment, which can contribute to improving trauma prevention and intervention strategies.
BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE
(2023)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)