Article
Psychology, Clinical
Eileen P. Stech, Aileen Z. Chen, Maria J. Sharrock, Ashlee B. Grierson, Emily L. Upton, Alison E. J. Mahoney, Jessica R. Grisham, Jill M. Newby
Summary: This study found that internet-delivered exposure therapy is as effective and acceptable as multi-component internet-delivered cognitive behavioral therapy in treating panic disorder, with similar clinical outcomes and treatment satisfaction. Both treatments significantly reduced participants' panic disorder symptom severity, with effects maintained at follow-up assessments.
JOURNAL OF ANXIETY DISORDERS
(2021)
Article
Health Care Sciences & Services
Lara Ebenfeld, Dirk Lehr, David Daniel Ebert, Stefan Kleine Stegemann, Heleen Riper, Burkhardt Funk, Matthias Berking
Summary: This randomized controlled trial demonstrated that a guided hybrid web-based training program based on cognitive behavioral therapy can effectively reduce symptoms of panic disorder in adults, with even stronger effects observed at 3 and 6 months follow-up assessments.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Psychology, Clinical
J. Rubel, J. Quest, L. Pruessner, C. Timm, S. Hartmann, S. Barnow, L. Rittmeyer, D. Rosenbaum, C. Lalk
Summary: This study aims to evaluate the efficacy of an online self-help program for panic disorder and its benefits for the German healthcare system.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2022)
Article
Psychology, Clinical
Martin Polak, Norbert K. Tanzer, Kathrin Bauernhofer, Gerhard Andersson
Summary: The study found that disorder-specific guided self-help iCBT for adult panic disorder sufferers was equally effective as various active CBT interventions in reducing symptoms. Comparing to inactive controls, there were large effect sizes in reducing symptoms and moderate changes in quality of life in the short term. Factors like baseline severity, country of origin, and treatment adherence were identified as significant moderators of iCBT treatment.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2021)
Article
Psychiatry
Bokyoung Shin, Jooyoung Oh, Byung-Hoon Kim, Hesun Erin Kim, Hyunji Kim, Suji Kim, Jae-Jin Kim
Summary: This study investigated the potential of self-guided VR as an alternative to high-cost treatment for panic disorder. The mobile app-based VR intervention was effective in treating panic symptoms and restoring the autonomic nervous system, demonstrating the validity and cost-effectiveness of VR treatment.
JMIR MENTAL HEALTH
(2021)
Article
Psychology, Clinical
Rachel A. Schwartz, Dianne L. Chambless, Jacques P. Barber, Barbara Milrod
Summary: This study evaluated clinicians' beliefs about barriers to progress in cognitive-behavioral therapy (CBT) for panic disorder using data from a randomized controlled trial. The results showed that perceived barriers did not predict poor outcomes, and dissociation during panic attacks was actually associated with greater symptomatic improvement, contrary to clinicians' intuitions. Patients with PTSD or less severe panic disorder changed more rapidly in CBT than in panic-focused psycho dynamic psychotherapy. Overall, clinician agreement was inversely related to the strength of predictors.
Article
Psychiatry
Reoto Kijima, Hirofumi Tesen, Ryohei Igata, Naomichi Okamoto, Reiji Yoshimura
Summary: This study reports a case of a patient with PA presenting with agoraphobia and panic attacks, which improved after treatment with eplerenone.
Review
Psychiatry
Kwang-Yeon Choi
Summary: Anxiety disorders are commonly seen in patients with bipolar disorder, but the management of anxiety symptoms in comorbid conditions remains challenging. This study explores the combination of cognitive behavioral therapy (CBT) with valproate as an adjuvant therapy for patients who failed to respond to standard pharmacotherapy trials. The findings suggest that this combination therapy may be effective in ameliorating agoraphobia and panic symptoms in patients with comorbid bipolar disorder. The study also discusses the background preclinical research and the potential mechanisms underlying this combination therapy.
PSYCHIATRY INVESTIGATION
(2022)
Article
Medicine, Research & Experimental
Jari Planert, Alla Machulska, Anne-Sophie Hildebrand, Kati Roesmann, Esra Otto, Tim Klucken
Summary: This study aims to investigate the efficacy of short-term treatment applications including psychoeducation and self-guided virtual reality exposure therapy (VRET) for patients with panic disorder (PD) and agoraphobia (AG). The study will randomly assign participants to an experimental group receiving self-guided psychoeducation and VRET, or a control group receiving relaxation and stress-reduction training. Multiple assessments will be conducted to compare symptom severity and remission status.
Review
Clinical Neurology
Yuta Takano, Rui Ibata, Naho Machida, Ayaka Ubara, Isa Okajima
Summary: This study systematically reviewed and meta-analyzed the effectiveness of CBT-I in managing insomnia symptoms. The results showed that CBT-I improved the severity of insomnia, sleep onset latency, wakefulness after sleep onset, early morning awakening, and sleep efficiency. Additionally, CBT-I alleviated depressive and anxiety symptoms, as well as fatigue.
SLEEP MEDICINE REVIEWS
(2023)
Article
Medicine, General & Internal
Behzad Salmani, Francesco Mancini, Jafar Hasani, Zahra Zanjani
Summary: The study showed that combining anti-disgust cognitive intervention with CBT significantly reduced OCD severity, disgust propensity/sensitivity, and increased acceptance of disgust in the treatment of C-OCD. Additionally, participation in anti-disgust cognitive intervention was associated with a lower refusal rate for ERP sessions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychology, Clinical
Marit Knapstad, Otto R. F. Smith
Summary: The study found that PMHC effectively alleviated symptoms of social anxiety disorder and agoraphobia, with a significant portion of clients struggling with these symptoms. While caution in interpretation is needed, the results support the scale-up of PMHC and similar initiatives to meet the needs of individuals with SAD and/or agoraphobia.
DEPRESSION AND ANXIETY
(2021)
Article
Clinical Neurology
Ronald C. Petersen, Paul S. Aisen, J. Scott Andrews, Alireza Atri, Brandy R. Matthews, Dorene M. Rentz, Eric R. Siemers, Christopher J. Weber, Maria C. Carrillo
Summary: Alzheimer's disease (AD) clinical trials are designed to detect the impact of therapeutic intervention, and there has been considerable discussion on defining a clinically meaningful change in treatment outcomes. The complexity of AD pathology and the need for early intervention make it crucial to assess meaningful change over the course of clinical trials. The Alzheimer's Association has convened experts to discuss key considerations for interpreting data and re-evaluating the expectations of therapeutic interventions in AD.
ALZHEIMERS & DEMENTIA
(2023)
Article
Chemistry, Multidisciplinary
Oleksandr Sverdlov, Yevgen Ryeznik
Summary: Cognitive behavioral therapy (CBT) is an effective treatment option for various mental health disorders. In this study, the authors investigated the statistical issues in an experimental CBT intervention compared to a control group. They found that analysis of covariance (ANCOVA) and two-sample t-test are appropriate for inference, with ANCOVA producing estimates with lower variance and allowing for treatment comparisons at different levels of engagement. The authors also highlighted the importance of considering uncertainty in engagement patterns during study design.
APPLIED SCIENCES-BASEL
(2022)
Article
Health Care Sciences & Services
Kim Mathiasen, Tonny E. Andersen, Mia Beck Lichtenstein, Lars Holger Ehlers, Heleen Riper, Annet Kleiboer, Kirsten K. Roessler
Summary: This study compared the clinical effectiveness of internet-based cognitive behavioral therapy (iCBT) combined with traditional face-to-face therapy (FtF-CBT) in a blended format (B-CBT) for adult major depressive disorder. The results showed no significant difference in treatment efficacy between B-CBT and FtF-CBT at 6 months' follow-up. These findings suggest that B-CBT may be capable of producing treatment effects similar to FtF-CBT.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)