Article
Genetics & Heredity
Marta Landoni, Sara Missaglia, Daniela Tavian, Chiara Ionio, Paola Di Blasio
Summary: This study examined the impact of 5-HTTLPR polymorphism on prenatal and postnatal symptoms of depression and posttraumatic stress in women. The results showed that the SS genotype was associated with a higher risk of cognitive depressive symptoms and postpartum aspects of posttraumatic stress disorder.
PSYCHIATRIC GENETICS
(2022)
Article
Biochemistry & Molecular Biology
Arunabha Majumdar, Preksha Patel, Bogdan Pasaniuc, Roel A. Ophoff
Summary: This study used a machine learning algorithm and GWAS summary statistics to examine the association between 5-HTTLPR genotypes and neurobehavioral traits, finding no significant evidence of association. However, significant evidence was found linking this genotype to human adult height, BMI, and total cholesterol. The summary-statistics-based approach provides a systematic method for investigating the role of VNTRs and related genetic polymorphisms in disease risk and trait susceptibility.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2022)
Article
Clinical Neurology
Pengfei Cheng, Junxiang Zhang, Yu Wu, Wenting Liu, Jiaying Zhu, Ze Chen, Jiarui Zhang, Songwen Guan, Yiming Sun, Jingxia Wang
Summary: This meta-analysis study indicates that the 5-HTTLPR genotype (S/S-Allele) is associated with an increased risk of depression in PD, especially in the recessive model, showing significant correlations in both Caucasian and non-Caucasian subgroups. Therefore, effective measures should be taken to prevent the onset of depression in PD before it occurs.
ACTA NEUROLOGICA BELGICA
(2021)
Article
Clinical Neurology
Linda Garvert, Kevin Kirchner, Hans J. Grabe, Sandra Van der Auwera
Summary: Recent GWAS have found many single nucleotide polymorphisms that affect depressive disorders, suggesting that depression is a heterogeneous disorder influenced by numerous genetic variants with small effect sizes. However, there is limited understanding of the interaction between different genetic risk factors. This study used a genome-wide gene-gene interaction approach and identified a significant interaction effect between the DPF1 gene and the 5-HTTLPR gene on lifetime depression. DPF1, previously not associated with depressive disorders, is expressed exclusively in the brain and plays a major role in neuronal development and neuroplasticity.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2022)
Article
Clinical Neurology
Kanami Tsuno, Sumiyo Okawa, Midori Matsushima, Daisuke Nishi, Yuki Arakawa, Takahiro Tabuchi
Summary: This study revealed that at least 13% of postpartum women in Japan experienced postpartum depressive symptoms during the COVID-19 pandemic. Social restrictions and loss of social support were strongly associated with postpartum depression. Additionally, the loss of maternal autonomy in delivery and breastfeeding was also linked to postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Obstetrics & Gynecology
Beth A. Lewis, Katie Schuver, Shira Dunsiger, Lauren Samson, Amanda L. Frayeh, Carrie A. Terrell, Joseph T. Ciccolo, John Fischer, Melissa D. Avery
Summary: The study suggests that low-cost, brief, easily accessible wellness interventions for high-risk postpartum women can effectively prevent symptoms of depression, especially performing better than usual care at the 6-month mark. Exercise interventions may have a protective effect on perceived stress among high-risk postpartum women.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Clinical Neurology
Satoshi Shinohara, Sayaka Horiuchi, Ryoji Shinohara, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Reiji Kojima, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata
Summary: This study aimed to determine whether Japanese women with multiple pregnancy were at a high risk of developing postpartum depression (PPD) at 1 and 6 months postpartum. The results of a nationwide prospective cohort study found that multiple pregnancy may be associated with an increased risk of PPD at 6 months postpartum compared to singleton pregnancy.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Neurosciences
Shunsuke Tanahashi, Hisashi Tanii, Yoshiaki Konishi, Takeshi Otowa, Tsukasa Sasaki, Mamoru Tochigi, Yuji Okazaki, Hisanobu Kaiya, Motohiro Okada
Summary: This study found a significant interaction between the tri-allelic 5-HTTLPR genotype and comorbid depression and AG in patients with PD. Some anxiety and personality traits in PD may be influenced by the tri-allelic gene effect of 5-HTTLPR, suggesting genetic effects on the comorbidities of PD.
NEUROPSYCHOBIOLOGY
(2021)
Article
Clinical Neurology
Elizabeth C. Aviv, Emma G. Preston, Yael H. Waizman, Aridenne A. Dews, Genesis Flores, Darby E. Saxbe
Summary: This study examined the link between fathers' birth experiences and their postpartum mental health. The results indicated that subjective birth stress significantly predicted depressive symptoms in fathers at six months postpartum. Additionally, an association was found between mode of delivery and paternal subjective stress.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Marie Shigematsu-Locatelli, Takashi Kawano, Kahoko Yasumitsu-Lovell, Fabricio Miguel Locatelli, Masamitsu Eitoku, Narufumi Suganuma, Japan Environment And Children's Study Group
Summary: This study found an association between prenatal pain and postpartum depression, with a dose-dependent effect. Pregnant women experiencing persistent pain are at the highest risk of developing postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Eric M. Schoenfeld, Nishant K. Gupta, Shariful A. Syed, Anna Rozenboym, Sasha L. Fulton, Andrea P. Jackowski, Tarique D. Perera, Jeremy D. Coplan
Summary: The study suggests that bonnet macaques reared under stress, carrying the ?s?-allele and having smaller adolescent hippocampal volume, exhibit reduced neurogenesis in adulthood. The positive impact of ipsilateral hippocampal volume on neurogenesis levels was observed.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Eydie L. Moses-Kolko, Layla Banihashemi, Alison E. Hipwell
Summary: The study found that hippocampal gray matter volume was inversely associated with positive maternal caregiving, while similar findings in the vmPFC did not remain significant after correction for multiple comparisons. ELS, particularly physical assault, was associated with reduced GM volumes, but was unrelated to observed maternal caregiving.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Psychology, Multidisciplinary
Runfang Wang, Yaokun Shan
Summary: This study utilized bibliometric methods to analyze the hotspots and frontiers in postpartum depression research from 2017 to 2021. The results showed that the research hotspots in the field of postpartum depression in the past five years mainly focused on the risk factors for PPD and the impact of the COVID-19 epidemic on PPD. Furthermore, providing various aspects of social and family support to women with PPD is also a research trend. The study provides valuable information for guiding future research topics and development directions.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
Bochao Cheng, Neil Roberts, Yushan Zhou, Xiuli Wang, Yuanyuan Li, Yiming Chen, Yajun Zhao, Pengcheng Deng, Yajing Meng, Wei Deng, Jiaojian Wang
Summary: Post-Partum Depression (PPD) is a common health issue affecting women's emotional well-being and often co-occurs with anxiety (PPD-A). Adequate social support has been shown to protect against PPD and PPD-A, with specific changes in brain functional connectivity strength in different neural circuits associated with these disorders. Perceived social support mediates the relationship between brain connectivity strength in specific regions and symptoms of PPD and PPD-A, highlighting the potential role of social support as a biomarker for these conditions.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Psychology, Clinical
Kathrine Bang Madsen, Xiaoqin Liu, Clara Albinana, Bjarni Johann Vilhjalmsson, Esben Agerbo, Preben Bo Mortensen, David Michael Hougaard, Merete Nordentoft, Thomas Werge, Ole Mors, Anders D. Borglum, Trine Munk-Olsen
Summary: This study investigated whether genetic vulnerability to posttraumatic stress disorder (PTSD) increases the risk of postpartum depression (PPD) and found that genetic vulnerability to PTSD is associated with an increased risk of PPD. However, the genetic vulnerability to PTSD in PPD cases did not exceed that of women with depression at other times.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Developmental
Divya Mehta, Adrian B. Kelly, Kristin R. Laurens, Divna Haslam, Kate E. Williams, Kerryann Walsh, Philip R. A. Baker, Hannah E. Carter, Nigar G. Khawaja, Oksana Zelenko, Ben Mathews
Summary: This review focuses on child maltreatment, highlighting the high prevalence rates and long-term mental health effects. The review also presents five recommendations on measuring trends, studying brain structures and processes, improving teleservices, implementing community-based approaches, and building interdisciplinary alliances.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Psychology, Developmental
Frances L. Doyle, Sophie J. Dickson, Valsamma Eapen, Paul J. Frick, Eva R. Kimonis, David J. Hawes, Caroline Moul, Jenny L. Richmond, Divya Mehta, Mark R. Dadds
Summary: Maternal-infant bonding is crucial for children's positive development, and poor bonding can lead to negative outcomes for both mothers and infants. This study examined predictors of bonding and found that younger maternal age, higher education, and higher levels of depressive symptoms before and after childbirth were associated with poorer bonding. Additionally, lower perceived social support and more difficult infant temperament were also linked to poorer bonding. These findings suggest that interventions targeting maternal psychopathology, lack of social support, and coping with difficult infant temperament may improve maternal-infant bonding.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Oncology
Ashley Weir, Eun-Young Kang, Nicola S. Meagher, Gregg S. Nelson, Prafull Ghatage, Cheng-Han Lee, Marjorie J. Riggan, Aleksandra Gentry-Maharaj, Andy Ryan, Naveena Singh, Martin Widschwendter, Jennifer Alsop, Michael S. Anglesio, Matthias W. Beckmann, Jessica Berger, Christiani Bisinotto, Jessica Boros, Alison H. Brand, James D. Brenton, Angela Brooks-Wilson, Michael E. Carney, Julie M. Cunningham, Kara L. Cushing-Haugen, Cezary Cybulski, Esther Elishaev, Ramona Erber, Sian Fereday, Anna Fischer, Luis Paz-Ares, Javier Gayarre, Blake C. Gilks, Marcel Grube, Paul R. Harnett, Holly R. Harris, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y. Hernandez, Sabine Heublein, Yajue Huang, Tomasz Huzarski, Anna Jakubowska, Mercedes Jimenez-Linan, Catherine J. Kennedy, Felix K. F. Kommoss, Jennifer M. Koziak, Bernhard Kraemer, Nhu D. Le, Jaime Lesnock, Jenny Lester, Jan Lubinski, Janusz Menkiszak, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Robles-Diaz, Matthias Ruebner, Mitul Shah, Raghwa Sharma, Yurii B. Shvetsov, Helen Steed, Aline Talhouk, Sarah E. Taylor, Nadia Traficante, Robert A. Vierkant, Chen Wang, Lynne R. Wilkens, Stacey J. Winham, Javier Benitez, Andrew Berchuck, David D. Bowtell, Francisco J. Candido dos Reis, Linda S. Cook, Anna DeFazio, Jennifer A. Doherty, Peter A. Fasching, Maria J. Garcia, Ellen L. Goode, Marc T. Goodman, Jacek Gronwald, David G. Huntsman, Beth Y. Karlan, Stefan Kommoss, Francesmary Modugno, Joellen M. Schildkraut, Hans-Peter Sinn, Annette Staebler, Linda E. Kelemen, Caroline E. Ford, Usha Menon, Paul D. P. Pharoah, Martin Koebel, Susan J. Ramus, D. Bowtell, A. DeFazio, N. Traficante, S. Fereday, A. Brand, P. Harnett, R. Sharma
Summary: Recently, a study found a positive correlation between protein expression of FOXJ1 and the 5-year survival rate of patients with tubo-ovarian high-grade serous carcinoma (HGSC). However, protein expression of GMNN was not significantly associated with patient survival. This study provides preliminary evidence for the prognostic value of FOXJ1 in HGSC and validates the prior mRNA-based prognostic association through immunohistochemistry.
BRITISH JOURNAL OF CANCER
(2023)
Article
Psychology, Developmental
Melanie Kungl, Pascal Vrticka, Christine Heinisch, Matthias W. Beckmann, Peter A. Fasching, Clara Ziegler, Gottfried Spangler
Summary: Neurophysiological evidence suggests a link between attachment and the neural processing of emotion expressions. This study examines this relationship in middle childhood and investigates the impact of facial familiarity. The results show that attachment deactivation is associated with increased vigilance towards angry faces, while no effect of hyperactivation is found.
ATTACHMENT & HUMAN DEVELOPMENT
(2023)
Article
Medicine, Research & Experimental
Min Huang, Peter A. Fasching, Amin Haiderali, Weiguang Xue, Chelsey Yang, Wilbur Pan, Zheng-Yi Zhou, Peter Hu, Mitashri Chaudhuri, Celine Le Bailly De Tilleghem, Nicolas Cappoen, Joyce O'Shaughnessy
Summary: This study evaluated the cost-effectiveness of adding pembrolizumab to neoadjuvant chemotherapy and continuing it as a single-agent adjuvant treatment for high-risk eTNBC in the USA. The results showed that pembrolizumab in combination with chemotherapy is a cost-effective option for these patients.
ADVANCES IN THERAPY
(2023)
Article
Oncology
Hanna Huebner, Matthias Ruebner, Christian Kurbacher, Peyman Hadji, Andreas D. Hartkopf, Michael P. Lux, Jens Huober, Sabrina Uhrig, Florin-Andrei Taran, Friedrich Overkamp, Hans Tesch, Lothar Haeberle, Diana Lueftner, Markus Wallwiener, Volkmar Mueller, Matthias W. Beckmann, Alexander Hein, Erik Belleville, Michael Untch, Wolfgang Janni, Tanja N. Fehm, Hans-Christian Kolberg, Diethelm Wallwiener, Sara Y. Brucker, Andreas Schneeweiss, Johannes Ettl, Peter A. Fasching, Laura L. Michel
Summary: The PRAEGNANT study is a registry study that analyzed genetic alterations in 37 breast cancer predisposition genes for 396 metastatic breast cancer patients. The study aimed to return genetic results to physicians and evaluate the impact on treatment decisions and patients' quality of life. Evaluation of the study scored 7 out of 10.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Oncology
Eun-Young Kang, Ashley Weir, Nicola S. Meagher, Kyo Farrington, Gregg S. Nelson, Prafull Ghatage, Cheng-Han Lee, Marjorie J. Riggan, Adelyn Bolithon, Gordana Popovic, Betty Leung, Katrina Tang, Neil Lambie, Joshua Millstein, Jennifer Alsop, Michael S. Anglesio, Beyhan Ataseven, Ellen Barlow, Matthias W. Beckmann, Jessica Berger, Christiani Bisinotto, Hans Boesmueller, Jessica Boros, Alison H. Brand, Angela Brooks-Wilson, Sara Y. Brucker, Michael E. Carney, Yovanni Casablanca, Alicia Cazorla-Jimenez, Paul A. Cohen, Thomas P. Conrads, Linda S. Cook, Penny Coulson, Madeleine Courtney-Brooks, Daniel W. Cramer, Philip Crowe, Julie M. Cunningham, Cezary Cybulski, Kathleen M. Darcy, Mona A. El-Bahrawy, Esther Elishaev, Ramona Erber, Rhonda Farrell, Sian Fereday, Anna Fischer, Maria J. Garcia, Simon A. Gayther, Aleksandra Gentry-Maharaj, C. Blake Gilks, Marcel Grube, Paul R. Harnett, Shariska Petersen Harrington, Philipp Harter, Arndt Hartmann, Jonathan L. Hecht, Sebastian Heikaus, Alexander Hein, Florian Heitz, Joy Hendley, Brenda Y. Hernandez, Susanna Hernando Polo, Sabine Heublein, Akira Hirasawa, Estrid Hogdall, Claus K. Hogdall, Hugo M. Horlings, David G. Huntsman, Tomasz Huzarski, Andrea Jewell, Mercedes Jimenez-Linan, Michael E. Jones, Scott H. Kaufmann, Catherine J. Kennedy, Dineo Khabele, Felix K. F. Kommoss, Roy F. P. M. Kruitwagen, Diether Lambrechts, Nhu D. Le, Marcin Lener, Jenny Lester, Yee Leung, Anna Linder, Liselore Loverix, Jan Lubinski, Rashna Madan, G. Larry Maxwell, Francesmary Modugno, Susan L. Neuhausen, Alexander Olawaiye, Siel Olbrecht, Sandra Orsulic, Jose Palacios, Celeste Leigh Pearce, Malcolm C. Pike, Carmel M. Quinn, Ganendra Raj Mohan, Cristina Rodriguez-Antona, Matthias Ruebner, Andy Ryan, Stuart G. Salfinger, Naoko Sasamoto, Joellen M. Schildkraut, Minouk J. Schoemaker, Mitul Shah, Raghwa Sharma, Yurii B. Shvetsov, Naveena Singh, Gabe S. Sonke, Linda Steele, Colin J. R. Stewart, Karin Sundfeldt, Anthony J. Swerdlow, Aline Talhouk, Adeline Tan, Sarah E. Taylor, Kathryn L. Terry, Aleksandra Toloczko, Nadia Traficante, Koen K. Van de Vijver, Maaike A. van der Aa, Toon Van Gorp, Els Van Nieuwenhuysen, Lilian Van-Wagensveld, Ignace Vergote, Robert A. Vierkant, Chen Wang, Lynne R. Wilkens, Stacey J. Winham, Anna H. Wu, Javier Benitez, Andrew Berchuck, Francisco J. Candido Dos Reis, Anna DeFazio, Peter A. Fasching, Ellen L. Goode, Marc T. Goodman, Jacek Gronwald, Beth Y. Karlan, Stefan Kommoss, Usha Menon, Hans-Peter Sinn, Annette Staebler, James D. Brenton, David D. Bowtell, Paul D. P. Pharoah, Susan J. Ramus, Martin Kobel
Summary: This study validates that high-level amplification of CCNE1 is associated with shorter survival in tubo-ovarian high-grade serous carcinoma (HGSC), supporting its use as a prognostic biomarker in this disease.
Article
Genetics & Heredity
Stefanie H. Mueller, Alvina G. Lai, Maria Valkovskaya, Kyriaki Michailidou, Manjeet K. Bolla, Qin Wang, Joe Dennis, Michael Lush, Zomoruda Abu-Ful, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Thais Baert, Laura E. Beane Freeman, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Natalia Bogdanova, Stig E. Bojesen, Bernardo Bonanni, Hermann Brenner, Sara Y. Brucker, Saundra S. Buys, Jose E. Castelao, Tsun L. Chan, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Wendy K. Chung, Sarah Colonna, Sten Cornelissen, Fergus J. Couch, Kamila Czene, Mary B. Daly, Peter Devilee, Thilo Dork, Laure Dossus, Miriam Dwek, Diana M. Eccles, Arif B. Ekici, A. Heather Eliassen, Christoph Engel, D. Gareth Evans, Peter A. Fasching, Olivia Fletcher, Henrik Flyger, Manuela Gago-Dominguez, Yu-Tang Gao, Montserrat Garcia-Closas, Jose A. Garcia-Saenz, Jeanine Genkinger, Aleksandra Gentry-Maharaj, Felix Grassmann, Pascal Guenel, Melanie Gundert, Lothar Haeberle, Eric Hahnen, Christopher A. Haiman, Niclas Hakansson, Per Hall, Elaine F. Harkness, Patricia A. Harrington, Jaana M. Hartikainen, Mikael Hartman, Alexander Hein, Weang-Kee Ho, Maartje J. Hooning, Reiner Hoppe, John L. Hopper, Richard S. Houlston, Anthony Howell, David J. Hunter, Dezheng Huo, Abctb Investigators, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M. John, Michael E. Jones, Audrey Jung, Rudolf Kaaks, Daehee Kang, Elza K. Khusnutdinova, Sung-Won Kim, Cari M. Kitahara, Stella Koutros, Peter Kraft, Vessela N. Kristensen, Katerina Kubelka-Sabit, Allison W. Kurian, Ava Kwong, James Lacey, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Keitaro Matsuo, Dimitrios Mavroudis, Usha Menon, Kenneth Muir, Rachel A. Murphy, Heli Nevanlinna, William G. Newman, Dieter Niederacher, Katie M. O'Brien, Nadia Obi, Kenneth Offit, Olufunmilayo Olopade, Andrew F. Olshan, Hakan Olsson, Sue K. Park, Alpa Patel, Achal Patel, Charles M. Perou, Julian Peto, Paul D. P. Pharoah, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Paolo Radice, Dhanya Ramachandran, Muhammad U. Rashid, Gad Rennert, Atocha Romero, Kathryn J. Ruddy, Matthias Ruebner, Emmanouil Saloustros, Dale P. Sandler, Elinor J. Sawyer, Marjanka K. Schmidt, Rita K. Schmutzler, Michael O. Schneider, Christopher Scott, Mitul Shah, Priyanka Sharma, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Harald Surowy, Rulla M. Tamimi, William J. Tapper, Jack A. Taylor, Soo Hwang Teo, Lauren R. Teras, Amanda E. Toland, Rob A. E. M. Tollenaar, Diana Torres, Gabriela Torres-Mejia, Melissa A. Troester, Therese Truong, Celine M. Vachon, Joseph Vijai, Clarice R. Weinberg, Camilla Wendt, Robert Winqvist, Alicja Wolk, Anna H. Wu, Taiki Yamaji, Xiaohong R. Yang, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, Alison M. Dunning, Douglas F. Easton, Harry Hemingway, Ute Hamann, Karoline B. Kuchenbaecker
Summary: This study identified 14 genes associated with breast cancer using gene-based aggregation analysis, including two newly discovered genes FMNL3 and AC058822.1. Furthermore, associations with established candidate genes like ESR1 were found through the collaboration of multi-ancestral cohorts, highlighting the importance of diversifying study cohorts. These findings provide new insights into the development of breast cancer.
Article
Medicine, General & Internal
Carla E. Schulmeyer, Peter A. Fasching, Lothar Haeberle, Julia Meyer, Michael Schneider, David Wachter, Matthias Ruebner, Patrik Poeschke, Matthias W. Beckmann, Arndt Hartmann, Ramona Erber, Paul Gass
Summary: The study evaluated the prognosis of patients with triple-negative breast cancer (TNBC) and other subtypes by using a biomarker panel including cytokeratin 5 (CK5), cluster of differentiation 117 (CD117), and epidermal growth factor receptor (EGFR). The results showed that the non-TBN subgroup of TNBC lesions with at least one positive biomarker (CK5, CD117, and/or EGFR) had longer disease-free survival (DFS) and overall survival (OS). This highlights the importance of molecular-based subclassifications of breast cancer for treatment options and prognosis stratification.
Article
Pediatrics
Stefan A. Mestermann, Peter A. W. Fasching, Matthias W. Beckmann, Jennifer Gerlach, Oliver H. Kratz, Gunther H. Moll, Johannes Kornhuber, Anna Eichler
Summary: Pregnancy anamnesis is crucial for child and adolescent psychiatry diagnostics. This study aimed to evaluate women's recall of prenatal events and found that retrospective self-reporting was not always accurate. The reliability of self-reporting on prenatal alcohol, smoking, partnership quality, pregnancy satisfaction, and obstetric complications varied.
Article
Clinical Neurology
Leonard P. Wenger, Oliver Hamm, Christiane Muehle, Sabine Hoffmann, Iris Reinhard, Patrick Bach, Johannes Kornhuber, Georg W. Alpers, Falk Kiefer, Tagrid Lemenager, Bernd Lenz
Summary: In this study, it was found that alcohol may affect trust in others not through modulation of oxytocin and androgens, but by inhibiting an increase in dihydrotestosterone. The study also confirmed the effects of alcohol on positive affect and risk-taking. These findings provide novel mechanistic insight into the influence of alcohol on social facilitation.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Chemistry, Medicinal
Nicolas Hoertel, Katayoun Rezaei, Marina Sanchez-Rico, Alfonso Delgado-Alvarez, Johannes Kornhuber, Erich Gulbins, Mark Olfson, Charles Ouazana-Vedrines, Alexander Carpinteiro, Celine Cougoule, Katrin Anne Becker, Jesus M. Alvarado, Frederic Limosin
Summary: The study suggests that the use of medications inhibiting acid sphingomyelinase (FIASMA) can reduce the risk of mortality in patients with SARS-CoV-2 infection. The multicenter retrospective observational study included 72,105 adult patients and found a significant association between FIASMA medication use and reduced 28-day mortality risk.
Article
Health Care Sciences & Services
Stefan Mestermann, Marie A. Arndt, Peter W. Fasching, Matthias Beckmann, Oliver H. Kratz, Gunther Moll, Johannes Kornhuber, Anna Eichler, IMAC Mind Consortium
Summary: This study analyzed paternal contributions to child well-being and found that father psychopathology significantly predicted girls' quality of life, while maternal parenting behavior had a significant influence on boys' quality of life. Fathers face different individual stressors and have different parenting behavior compared to mothers, but their influences are still significant, especially for daughters. Therefore, father-addressed pre- and intervention programs in child psychotherapeutic treatment are of high relevance.
Review
Psychology, Clinical
Monique L. Mefrouche, Eva-Maria Siegmann, Stephanie Boehme, Matthias Berking, Johannes Kornhuber
Summary: This study conducted a systematic review and meta-analysis to investigate the effects of digital-based mindfulness interventions on depressive, anxiety, and stress symptoms during pregnancy. The results indicated that digital mindfulness interventions were effective in reducing depression and anxiety symptoms, but had no significant effect on stress symptoms. The attrition rate and primiparity were found to moderate the intervention effect.
EUROPEAN JOURNAL OF INVESTIGATION IN HEALTH PSYCHOLOGY AND EDUCATION
(2023)
Article
Obstetrics & Gynecology
Michael O. Schneider, Jutta Pretscher, Tamme W. Goecke, Lothar Haeberle, Anne Engel, Johannes Kornhuber, Anna Eichler, Arif B. Ekici, Matthias W. Beckmann, Peter A. Fasching, Eva Schwenke
Summary: This study did not find any association between the candidate haplotypes analyzed in PGR and CYP19A1 genes, as well as single SNPs in ESR1 and COMT genes, with depression scores assessed by EPDS in a cohort of healthy unselected pregnant women.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)